Abstract:
본 발명은 생체적합성 및 저마찰성이 우수한 수술용 봉합사 및 이의 제조방법에 관한 것으로, 본 발명에 따른 봉합사는 생체적합성 및 저마찰성이 우수하여 봉합 시 환자에게 발생할 수 있는 통증을 감소시키고, 봉합 부위의 세포에서 염증 발생을 최소화하면서도 세포와의 접촉성이 우수하여, 다양한 내과용 및 외과용 수술에 활용될 수 있다.
Abstract:
Disclosed herein are compositions to use in biofouling-resistant coatings, biofouling-resistant coatings, methods of making biofouling-resistant coatings, biofouling-resistant devices, and methods of making biofouling-resistant devices.
Abstract:
The present disclosure provides a coating applicator operable to apply a coating of a therapeutic agent upon an object comprising an openable and sealable device compartment, a therapeutic agent positioned in communication with the device compartment, an atomizer operable to atomize the therapeutic agent, and a source of vacuum in communication with the device compartment. The coating applicator may further comprise a drier, and the drier may comprise an arrangement to operate the source of vacuum for a time sufficient to promote drying of applied therapeutic agent. Deposition of the atomized therapeutic agent may be promoted by contacting the atomized therapeutic agent while the object is in a chilled condition and by contacting the object with atomized therapeutic agent while the atomized therapeutic agent is in a heated condition. Related methods are also disclosed.
Abstract:
본 발명은 별도로 제작된 다수의 리테이너가 봉합사의 길이방향으로 삽입되어 봉합사에 고정됨에 따라 인체 내에 삽입된 봉합사가 리테이너 구조를 통해 체내 조직을 보다 견고하게 유지시켜 줄 수 있는 생분해성 봉합사 및 그의 제조방법에 관한 것이다. 리테이너를 갖는 생분해성 봉합사의 제조방법의 일실시예는, 길이방향으로 길게 형성되는 생분해성 봉합사바디를 마련하는 단계와 생분해성 재질의 다수 개의 리테이너의 중앙부를 관통하여 삽입홀을 마련하는 단계와 리테이너를 봉합사바디로 삽입하여 봉합사바디의 외주면을 따라 서로 이격되게 배치하는 단계와 리테이너를 봉합사바디의 외주면에 고정하는 단계를 포함하는 것일 수 있다.
Abstract:
Antimicrobial formulations and coatings for medical devices and processes therefor are disclosed. The formulations include at least one water permeable polymer with at least one antimicrobial agent in a liquid medium and are prepared by wet milling the components and can form antimicrobial coatings having uniformly dispersed particles having an average size of no greater than 50 microns.
Abstract:
A barbed suture and a method of forming a barbed suture are disclosed. The barbed suture includes a core fiber and a sheet, which can be monolithic or formed from a plurality of longitudinally extending fibers, which is placed around the core fiber.
Abstract:
A tissue fixation device includes an elongated body defining a longitudinal axis and including a proximal end and a distal end. At least two barbed segments diverge distally away from the distal end of the elongated body and a pledget is disposed at distal ends of the barbed segments. The elongated body, barbed segments, and pledget are provided in a variety of configurations depending upon the performance requirements desired of the tissue fixation device for the envisaged application of use.
Abstract:
The invention concerns a suture coated with albumin (an albumin-coated suture) for use in introducing cells seeded thereon into a soft tissue of a patient. The suture of the invention advantageously comprises cells seeded thereon. The suture of the invention is advantageously coated with human serum albumin. The cells seeded on the suture of the invention are advantageously non-embryonic stem cells. The present invention further concerns a method for coating a surgical suture with albumin comprising incubating said suture in an albumin containing aqueous solution. The invention further provides a method for seeding cells onto an albumin-coated suture comprising incubating an albumin-coated suture in a cell culture comprised in a liquid cell culture medium. The invention further provides a method for using an albumin-coated suture for introducing cells seeded thereon into a soft tissue of a patient. The invention further concerns a method for introducing cells into a soft tissue of a patient comprising introducing an albumin-coated suture into said soft tissue of said patient, wherein said albumin-coated suture comprises said cells to be introduced seeded thereon.
Abstract:
A medical device for installing sutures to close an incision in tissue or human skin is disclosed. The suturing device may provide first and second arcuate needles. Once properly positioned, the first and second arcuate needles are driven through the sub-dermal layer, or alternatively through a superficial surface, of two sections of skin to be joined. This is done in arcuate fashion and at identical and symmetrical rates of angular displacement. In so doing, the sections of skin are pushed toward one another thus assuring horizontal and vertical alignment of the two sections of skin. During the driving or retraction process of the first and second arcuate needles, a suture is positioned within both the first and second sections of skin and transformed from a planar or a multi-planar serpentine orientation to a helical orientation. The resulting suturing process is thus much faster than conventional or manual suturing and results in superior wound approximation/alignment that will lead to decreased scarring compared to prior art devices.