医療用縫合糸
    2.
    发明申请
    医療用縫合糸 审中-公开

    公开(公告)号:WO2021117514A1

    公开(公告)日:2021-06-17

    申请号:PCT/JP2020/044309

    申请日:2020-11-27

    Inventor: 松田 純平

    Abstract: 巻き癖がつき難いまたはついた巻き癖が容易に解消される医療用縫合糸を提供する。 医療用縫合糸100は、芯糸110と外層糸120とで構成されている。芯糸110は、複数の極細糸111を撚って構成されており、医療用縫合糸100の中心部に配置されている。極細糸111は、線材111aの外表面に2-メタクリロイルオキシエチルホスホリルコリン(MPC)からなる内線カバー層112が形成されている。外層糸120は、複数の極細糸121で編んで構成されており、芯糸110の外表面を覆っている。極細糸121は、線材121aの外表面にMPCからなる外線カバー層122が形成されている。内線カバー層112および外線カバー層122は、線材111a,121aの各総重量の0.05%以上かつ0.3%未満の重量の範囲内で線材111a,121aの外表面上に形成されている。 図2

    OPERATING ROOM COATING APPLICATOR AND METHOD

    公开(公告)号:WO2020110030A2

    公开(公告)日:2020-06-04

    申请号:PCT/IB2019/060231

    申请日:2019-11-27

    Applicant: ETHICON, INC.

    Abstract: The present disclosure provides a coating applicator operable to apply a coating of a therapeutic agent upon an object comprising an openable and sealable device compartment, a therapeutic agent positioned in communication with the device compartment, an atomizer operable to atomize the therapeutic agent, and a source of vacuum in communication with the device compartment. The coating applicator may further comprise a drier, and the drier may comprise an arrangement to operate the source of vacuum for a time sufficient to promote drying of applied therapeutic agent. Deposition of the atomized therapeutic agent may be promoted by contacting the atomized therapeutic agent while the object is in a chilled condition and by contacting the object with atomized therapeutic agent while the atomized therapeutic agent is in a heated condition. Related methods are also disclosed.

    리테이너를 갖는 생분해성 봉합사 및 그의 제조방법

    公开(公告)号:WO2019054565A1

    公开(公告)日:2019-03-21

    申请号:PCT/KR2017/013637

    申请日:2017-11-28

    Inventor: 유재원 신미향

    CPC classification number: A61B17/00 A61B17/06 A61L17/14 D02G3/44 D02J3/02

    Abstract: 본 발명은 별도로 제작된 다수의 리테이너가 봉합사의 길이방향으로 삽입되어 봉합사에 고정됨에 따라 인체 내에 삽입된 봉합사가 리테이너 구조를 통해 체내 조직을 보다 견고하게 유지시켜 줄 수 있는 생분해성 봉합사 및 그의 제조방법에 관한 것이다. 리테이너를 갖는 생분해성 봉합사의 제조방법의 일실시예는, 길이방향으로 길게 형성되는 생분해성 봉합사바디를 마련하는 단계와 생분해성 재질의 다수 개의 리테이너의 중앙부를 관통하여 삽입홀을 마련하는 단계와 리테이너를 봉합사바디로 삽입하여 봉합사바디의 외주면을 따라 서로 이격되게 배치하는 단계와 리테이너를 봉합사바디의 외주면에 고정하는 단계를 포함하는 것일 수 있다.

    PROTEIN COATED BIOACTIVE SUTURE FOR CELL TRANSPLANTATION AND METHOD FOR PRODUCING THEREOF
    9.
    发明申请
    PROTEIN COATED BIOACTIVE SUTURE FOR CELL TRANSPLANTATION AND METHOD FOR PRODUCING THEREOF 审中-公开
    用于细胞移植的蛋白质包衣生物活性剂及其生产方法

    公开(公告)号:WO2013027189A1

    公开(公告)日:2013-02-28

    申请号:PCT/IB2012/054271

    申请日:2012-08-23

    CPC classification number: A61L17/145 A61L17/005 A61L2430/34

    Abstract: The invention concerns a suture coated with albumin (an albumin-coated suture) for use in introducing cells seeded thereon into a soft tissue of a patient. The suture of the invention advantageously comprises cells seeded thereon. The suture of the invention is advantageously coated with human serum albumin. The cells seeded on the suture of the invention are advantageously non-embryonic stem cells. The present invention further concerns a method for coating a surgical suture with albumin comprising incubating said suture in an albumin containing aqueous solution. The invention further provides a method for seeding cells onto an albumin-coated suture comprising incubating an albumin-coated suture in a cell culture comprised in a liquid cell culture medium. The invention further provides a method for using an albumin-coated suture for introducing cells seeded thereon into a soft tissue of a patient. The invention further concerns a method for introducing cells into a soft tissue of a patient comprising introducing an albumin-coated suture into said soft tissue of said patient, wherein said albumin-coated suture comprises said cells to be introduced seeded thereon.

    Abstract translation: 本发明涉及一种涂有白蛋白的缝合线(一种白蛋白包被的缝合线),用于将接种于其上的细胞引入患者的软组织中。 本发明的缝线有利地包括接种在其上的细胞。 本发明的缝线有利地用人血清白蛋白包被。 接种在本发明的缝合线上的细胞有利地是非胚胎干细胞。 本发明还涉及用白蛋白涂覆外科缝合线的方法,包括在含白蛋白的水溶液中孵育所述缝线。 本发明还提供了将细胞接种到白蛋白包被的缝合线上的方法,包括在包含在液体细胞培养基中的细胞培养物中孵育白蛋白包被的缝合线。 本发明还提供了一种使用白蛋白包被的缝合线将其上接种细胞的细胞导入患者的软组织中的方法。 本发明还涉及将细胞引入患者的软组织中的方法,包括将白蛋白包被的缝合线引入所述患者的所述软组织中,其中所述白蛋白包被的缝合线包含要引入的所述细胞接种于其上。

    SKIN SUTURING DEVICE USING ROTATING NEEDLES
    10.
    发明申请
    SKIN SUTURING DEVICE USING ROTATING NEEDLES 审中-公开
    使用旋转针的皮肤切割装置

    公开(公告)号:WO2012088232A3

    公开(公告)日:2012-10-11

    申请号:PCT/US2011066401

    申请日:2011-12-21

    Abstract: A medical device for installing sutures to close an incision in tissue or human skin is disclosed. The suturing device may provide first and second arcuate needles. Once properly positioned, the first and second arcuate needles are driven through the sub-dermal layer, or alternatively through a superficial surface, of two sections of skin to be joined. This is done in arcuate fashion and at identical and symmetrical rates of angular displacement. In so doing, the sections of skin are pushed toward one another thus assuring horizontal and vertical alignment of the two sections of skin. During the driving or retraction process of the first and second arcuate needles, a suture is positioned within both the first and second sections of skin and transformed from a planar or a multi-planar serpentine orientation to a helical orientation. The resulting suturing process is thus much faster than conventional or manual suturing and results in superior wound approximation/alignment that will lead to decreased scarring compared to prior art devices.

    Abstract translation: 公开了一种用于安装缝合线以封闭组织或人体皮肤中的切口的医疗装置。 缝合装置可以提供第一和第二弓形针。 一旦适当地定位,第一和第二弓形针被驱动穿过待被连接的两部分皮肤的次真皮层,或者可选地通过表面。 这是以弓形方式并以相同和对称的角位移速率完成的。 在此过程中,皮肤部分被推向彼此,从而确保两部分皮肤的水平和垂直对齐。 在第一和第二弓形针的驱动或回缩过程中,将缝合线定位在皮肤的第一和第二部分内并且从平面或多平面蛇形取向变换为螺旋取向。 由此产生的缝合过程因此比传统或手动缝合快得多,并且导致与现有技术装置相比将导致疤痕减少的优越伤口近似/对准。

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