Abstract:
Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by application of an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The methods may further be performed by application of an initiation energy to a subject in situ to activate a pharmaceutical agent directly or via an energy modulation agent, optionally in the presence of one or more plasmonics active agents, thus producing an effect on or change to the target structure. Kits containing products or compositions formulated or configured and systems for use in practicing these methods.
Abstract:
A system and method are disclosed for harmonic modulation of standing wavefields for spatial focusing, manipulation, and patterning of particles, cells, powders, aerosols, colloids, and solids using a multifrequency wave source (1302), a chamber (1304) a control module (1306) and an analysis module (1308) to generate standard wavefields useful for tissue engineering, micro fabrication, therapeutic treatment, and diagnostic tests. A method for tissue engineering is also disclosed.
Abstract:
Novel systems for delivering therapeutic agents to target tissues are disclosed. The guidewire (520) and cannula (500) configurations enable rapid and repeated treatments of the target tissue without the need for subsequent imaging. The cannula is coupled to a source of ultrasound, radiation, radiofrequency energy, or chemotherapeutic agents which can then be delivered to from the cannula the target tissue. The system can be used to treat tumors that are small or surgically inoperable. In addition the system can be used to treat lymphatic tissue that may contain metastases from the tumors.
Abstract:
Изобретение относится области антенной техники и может использоваться для эффективной концентрации излучения распределенного источника на объект, расположенный в фокальной зоне. Техническим результатом заявленного изобретения является повышение эффективности передачи излучения от источника объекту за счет повышения концентрации излучения в фокальной зоне. Универсальное устройство для передачи излучения от источника объекту содержит две антенны, каждая из которых выполнена в виде усеченного сегмента сферической поверхности, источник излучения, размещенный в плоскости раскрыва одной из антенн, и объект, размещенный в совмещенной фокальной зоне обоих антенн. Антенны установлены друг против друга на расстоянии, превышающем радиус сферической поверхности на величину, составляющую не менее 0,01 от радиуса сферической поверхности, а источник излучения выполнен распределенным. Устройство дополнительно может быть снабжено второй парой таких антенн с фокальной зоной в виде объемного креста или третьей парой антенн с возможностью создания объемной совместной фокальной зоны в виде трехкоординатного креста. Кроме того, устройство может быть дополнительно снабжено вторым источником излучения, размещенным в плоскости раскрыва второй антенны, а сами антенны могут являться элементами камеры.
Abstract:
The present invention relates to a system with temperature control in a target area within a body. The system comprises a device, such as an electrode or reflector, configured to be fixated to the target area within the body; a first antenna element; a control unit configured to generate a first RF- signal to be transmitted from the first antenna element; and a plurality of external antenna elements, each external antenna element being configured to receive a reception signal originating from said RF- signal. The control unit determines electrical properties of tissue within the body based on the reception signals; calculates and generates transmission signals based on the determined electrical properties of tissue; and transmits the transmission signals from the external antenna elements to transfer energy to a point within the target area to increase the temperature in the target area.
Abstract:
Systems, methods and devices for creating an effect using microwave energy to specified tissue are disclosed herein. A system for the application of microwave energy to a tissue can include, in some embodiments, a signal generator adapted to generate a microwave signal having predetermined characteristics, an applicator connected to the generator and adapted to apply microwave energy to tissue, the applicator comprising one or more microwave antennas and a tissue interface, a vacuum source connected to the tissue interface, a cooling source connected to said tissue interface, and a controller adapted to control the signal generator, the vacuum source, and the coolant source. The tissue may include a first layer and a second layer, the second layer below the first layer, and the controller is configured such that the system delivers energy such that a peak power loss density profile is created in the second layer.
Abstract:
Provided are systems and methods that employ microwave energy to selectively destroy damaged or diseased tissue such as tumors in the prostate, brain, breast, and other anatomical locations.
Abstract:
Изобретение относится к области медицины. Устройство для физиотерапевтического воздействия содержит аппарат физиотерапевтического воздействия, блок управления и блок локализации воздействия, соединенный с зоной локализации воздействия, а также жесткое основание и блок перемещения по координатам х, у, z, при этом аппарат физиотерапевтического воздействия выполнен в виде рамы, установленной на жестком основании с возможностью перемещения в линейных координатах х, у, z и п источников физиотерапевтического воздействия, расположенных по периметру рамы, соединенной механически с соответствующими выходами блока перемещения по координатам х, у, z, входы которого подключены к соответствующим выходам по координатам х, у, z блока управления, соответствующие входы которого соединены с дополнительными выходами блока перемещения по координатам х, у, z, при этом управляющий вход блока управления соединен с выходом блока локализации воздействия.
Abstract:
The invention relates to a lens which concentrates or focuses the near field generated by an electromagnetic wave source. The focusing process produces an image of the source with a spatial resolution less than the wavelength. The inventive lens is particularly suitable for use in medical microwave hyperthermia therapy.Said therapy is based on increasing the temperature experienced by organic tissues upon absorption of microwave radiation. Given that the lens can concentrate the electromagnetic microwave field within a very specific region of space, it can be used to raise the temperature of a determined region of tissue without affecting the surrounding tissue. The lens can also be used more generally for any process that requires localised heating with the application of microwaves or any other means. The invention can also be used to focus fields at the megahertz or terazertz frequency.
Abstract:
Neoplastic tissue, viral and bacterial infections, and other physiological disorders and conditions are treated by irradiation of the host with electromagnetic radiation at a wavelength that is differentially absorbed by the offending tissue or cells. Radiation with differential absorption is also used in the sterilization of articles and packing made from synthetic polymers and for the treatment of food stuffs.