Abstract:
The invention is about an occluder device which is used for treatment through transcatheter in order to occlude congenital heart defects, vascular abnormalities or left atrial appendage and about production process of the device. The device contains biocompatible wire cage made of either a memory metal, or an alloy, or a polymeric material. The device also contains a thread mesh retained to the wire cage and an artificial or natural acellular dermal matrix. The distal retention zone is designed as a hollow "whirling dervish's skirt", and can be circular, oval, triangular according to the type of defect it will occlude. The device may comprise a marker. This special designed device is lighter, and has lower metal loadings than its counterparts. The production process is simpler, and the dermal matrix it contains enables a faster recovery and high complete occlusion success rate. The devices for occluding the left atrial appendage have been designed for narrow or broad defects, and the surfaces of the proximal retention area facing the left atrium has been coated with biocompatible and antifibrin material so that its nickel-titanium alloy content cannot lead to new thrombus formation.
Abstract:
A device that, when implanted in the heart, closes the wound and complies with wall motion (i.e., expands and contracts with the myocardium).
Abstract:
A medical device (100) includes a balloon member (102), a port (108) that couples a compartment interior (106) of the balloon member to a region exterior of the balloon member, and a tubular member (104) that defines a lumen (105). A distal end (114) of the tubular member is attached to an internal surface (112) of the balloon member within the compartment so that a portion of the internal surface of the balloon member provides a seal (115) at a distal end (118) of the lumen. The tubular member passes through the port, and the proximal (end 122) of the tubular member is configured to remain exterior of the compartment. A delivery of a sufficient amount of a filling material into the lumen of the tubular member causes a length of the tubular member to pass through the port and into the balloon compartment.
Abstract:
An occlusion device and method for occluding an undesirable vascular structure, such as a septal defect or left atrial appendage. The occlusion device includes a lattice structure that expands from a contracted catheter-deliverable state to an expanded state that occludes the vascular structure. The lattice structure has one or more braided layers, with structural braided layers that provide structural support to the device, and occlusive layers that provide a lattice braiding or pore sizes that promote further occlusion by a biological process, such as tissue ingrowth that further occludes the affected vascular structure.
Abstract:
An occlusive device (100) includes a frame element (102) having a distal end (112) and a proximal end (110), and a delivery configuration and a deployed configuration. The occlusive device also includes an occlusive face (106) having a peripheral edge (114), where the occlusive face positioned toward the proximal end of the frame element. The occlusive device also includes at least one anchor (50) positioned at the peripheral edge of the occlusive face, where the at least one anchor extends at an acute angle to the peripheral edge of the occlusive face.
Abstract:
An implantable medical device (100) includes a frame that includes at least one elongate member (120). The implantable medical device also includes a fixation member (200) comprising a first cuff (210), a second cuff (220), a tissue engagement member (230) configured to anchor to tissue at an implant site to thereby hold the implantable medical device in a position at the implant site, and a cuff (240) joining member comprising an arcuate shape and connected at a first end to the first cuff and at a second end to the second cuff. The first cuff substantially surrounds a perimeter of a first portion of the at least one elongate member, the second cuff substantially surrounds a perimeter of a second portion of the at least one elongate member, and the cuff joining member does not substantially surround a perimeter of any portion of the at least one elongate member.
Abstract:
An occlusion device and method for occluding an undesirable passage through tissue, such as a septal defect, that provides an expandable cylinder or other structure that occludes the passage internally or by covering one or more openings to the passage. The occlusion device includes a wire lattice or mesh that expands from a contracted catheter-deliverable state to an expanded state that occludes the passage. The lattice or mesh has one or more layers, with layers that provide structural support to the device, and layers that provide a lattice braiding or pore sizes that promote further occlusion by a biological process, such as tissue ingrowth that further occludes the affected passage.
Abstract:
Systems and methods for occluding a left atrial appendage are disclosed. A left atrial appendage may be covered with a first occluder device to obstruct the passage of blood out of the left atrial appendage. The first occluder device may include an expandable member, a cover attached to and covering an end of the expandable member, and a one-way valve disposed in the cover. The cover may form a flexible pocket between the cover and the expandable member. The cover may be made of bioprosthetic material. A second occluder device may also be disposed within the left atrial appendage by inserting the second occluder device through the one-way valve in the cover of the first occluder device. The second occluder device may be used to stretch the left atrial appendage to obliterate the left atrial appendage.
Abstract:
An implant device for a heart having a first chamber and a second chamber and a native valve between the chambers, the device having an elongate body having opposing ends, the body being configured to be implanted within the heart and extend through the native valve with a first end in the first chamber and a second end in the second chamber; a first resiliently compressible part of the body being adapted to be compressively engaged by the heart within the first chamber; and a second resiliently compressible part of the body being adapted to be compressively engaged by the heart within the second chamber; so that the first and second parts hold the elongate body in a desired position within the heart by said compressive engagement. The device can be employed as a prosthetic device replace or supplement a native valve such as the mitral valve.
Abstract:
Devices and methods for modifying stomach volume include the formation of intragastric slots for wrapping one or more portions of the fundus therethrough with minimal interference with nerves and vasculature flow. Intragastric space occupying devices expand with environmental changes brought about by natural conditions inherent to the digestive cycle such as with changes in pH. Extragastric volume occupying balloons are placed into folded stomach sections. The balloons are fluidly coupled to external gastric filling devices. In yet another set of embodiments, methods and devices provide adjustable gastric volume reduction fundal wraps. In one embodiment, a device is placed in the fundus for Nissen fundoplication and permits postoperative adjustment to reach desired weight loss. Intragastric and extragastric balloons are optionally incorporated.