公开(公告)号：WO98045391A1

公开(公告)日：1998-10-15

申请号：PCT/EP1998/001821

申请日：1998-03-27

IPC: C07C303/24 ,  C07C305/06 ,  C07C305/10 ,  C08G65/26 ,  C08G65/334 ,  C08L71/02 ,  C11D1/14 ,  C11D1/16 ,  C11D1/29 ,  C11D3/34 ,  C11D17/00

CPC classification number: A61Q5/02 ,  A61K8/86 ,  C07C303/24 ,  C08G65/2609 ,  C08G65/3344 ,  C08L71/02 ,  C11D1/146 ,  C11D1/16 ,  C11D1/29 ,  C11D3/3409 ,  C07C305/10 ,  C07C305/06 ,  C08L71/00

Abstract: The invention relates to the use of glycerin sulfates of formula (I) as viscosity regulators for concentrated aqueous alkyl(ether) sulfate pastes, wherein Y and Z independently stand for a hydroxyl group pr a SO3M group, M stands for hydrogen, an alkaline metal or alkaline earth metal and the sum of n+m+p is 0 or represents numbers ranging from 1 to 50. Small amounts of said regulators significantly reduce viscosity even in alkyl(ether) sulfate pastes with a 70 wt. % content.

Abstract translation: 提出了使用式（I）的甘油硫酸盐的，独立地在Y彼此的并且Z是羟基或SO 3 M基，M表示氢，碱金属或碱土金属和之和（N + M + p）为0或 号码从1到50，如粘度调节剂为浓缩的水性烷基（醚）硫酸盐糊。 即使是少量的稳压器降低粘度和70％（重量） - 烷基硫酸钠（醚）糊剂显著。

公开(公告)号：WO1997038972A1

公开(公告)日：1997-10-23

申请号：PCT/US1997006338

申请日：1997-04-16

Applicant: THE PROCTER & GAMBLE COMPANY ,  CONNOR, Daniel, Stedman ,  CRIPE, Thomas, Anthony ,  JACOBS, Roger, Craig ,  JENSEN, Michael, Chris

Inventor： THE PROCTER & GAMBLE COMPANY

IPC: C07C303/24

CPC classification number: C11D3/18 ,  C07C303/24 ,  C07C305/06 ,  C07C305/10 ,  C11D1/123 ,  C11D1/126 ,  C11D1/146 ,  C11D1/29 ,  C11D1/521 ,  C11D1/72 ,  C11D3/08 ,  C11D3/128

Abstract: Sulfation methods for producing longer chain length alkyl sulfate and/or alkyl alkoxylated sulfate surfactant compositions. This method utilizes the presence of a significant amount of mid-chain branched alcohol and/or polyoxyalkylene alcohol in the sulfation reaction to significantly reduce the reaction temperature, thereby improving product quality and saving energy.

Abstract translation: 生产长链烷基硫酸盐和/或烷基烷氧基化硫酸盐表面活性剂组合物的硫酸盐法。 该方法利用在硫酸化反应中存在显着量的中链支化醇和/或聚氧化烯醇，以显着降低反应温度，从而提高产品质量并节约能源。

公开(公告)号：WO1996018609A1

公开(公告)日：1996-06-20

申请号：PCT/US1995015651

申请日：1995-11-30

Applicant: PROCEPT, INC.

Inventor： PROCEPT, INC. ,  ROBERTS, John, C. ,  PATCH, Raymond, J.

IPC: C07C303/24

CPC classification number: C07C309/77 ,  C07C303/02 ,  C07C303/28 ,  C07D311/72 ,  C07J31/006 ,  C07J41/0055 ,  Y02P20/55 ,  C07C309/39 ,  C07C309/59 ,  C07C309/74

Abstract: The present invention is a method of protecting a sulfonic acid functional group in an organic molecule as a substituted or unsubstituted neopentyl sulfonate ester. The method allows the conversion of R-SO3-H to R'-SO3-H, wherein R and R' are different organic radicals. Also disclosed is a method of increasing the bioavailability of drugs with a sulfonic acid functional group by protecting the sulfonic acid functional group as a substituted neopentyl sulfonate ester which has a masked heteroatom nucleophile. The masked nucleophile can be liberated in vivo, resulting in removal of the neopentyl protecting group and regeneration of the parent drug.

Abstract translation: 本发明是保护作为取代或未取代的新戊基磺酸酯的有机分子中的磺酸官能团的方法。 该方法允许将R-SO 3 -H转化为R'-SO3-H，其中R和R'是不同的有机基团。 还公开了通过保护磺酸官能团作为具有掩蔽的杂原子亲核试剂的取代的新戊基磺酸酯来提高具有磺酸官能团的药物的生物利用度的方法。 掩蔽的亲核试剂可以在体内释放，导致新戊基保护基的去除和母体药物的再生。

公开(公告)号：WO1995001959A1

公开(公告)日：1995-01-19

申请号：PCT/EP1994002145

申请日：1994-06-30

Applicant: HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN ,  BREUCKER, Christoph ,  KOMP, Horst, Dieter ,  SALZ, Rainer ,  SCHAMBIL, Fred ,  SCHMID, Karl

Inventor： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN

IPC: C07C303/24

CPC classification number: C11D3/0094 ,  C07C303/24 ,  C11D1/146 ,  C07C305/06

Abstract: The invention concerns alkyl sulphates with improved solubility, increased foaming power and a higher degree of sulphonation, the alkyl sulphates being obtained by sulphating, using per se prior art techniques, a mixture of fatty alcohols comprising: 0 to 1 % by wt. of C10 alcohols; 4 to 23 % by wt. of C12 alcohols; 1 to 13 % by wt. of C14 alcohols; 19 to 52 % by wt. of C16 alcohols; 34 to 62 % by wt. of C18 alcohols; 0 to 3 % by wt. of C20+ alcohols with sulphur trioxide or chlorosulphonic acid and subsequently neutralizing with bases. The alkyl sulphates thus obtained are suitable in particular for use in the production of extruded washing agents.

Abstract translation: 具有改善的溶解度的烷基硫酸盐，增加起泡力和更高的磺化度可以通过将组合物0的脂肪醇反应，以1重量％的C10获得; 4至23重量％C12; 1至13重量％C14; 19-52重量％的C16; 34重量％至62 C18; 以已知的方式0至3重量％C20 +硫酸化用气态三氧化硫或氯磺酸，然后用碱中和。 烷基硫酸盐是特别适合于生产Waschmittelextrudaten的。

公开(公告)号：WO1994013632A1

公开(公告)日：1994-06-23

申请号：PCT/EP1993003557

申请日：1993-12-13

Applicant: SHELL CANADA LIMITED ,  SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

Inventor： SHELL CANADA LIMITED ,  SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. ,  SCHISLA, David, Karl ,  TOMASKOVIC, Robert, Stephen ,  LUTZ, Eugene, Frederick ,  ARBORE, Charles, Michael

IPC: C07C303/24

CPC classification number: C07C303/44 ,  C07C303/24 ,  C11D1/146 ,  C11D3/128 ,  C11D11/04 ,  C07C305/06

Abstract: A process for preparing a surfactant composition comprising a secondary (C8 to C22) alkyl sulphate, which process comprises: a) sulphating a (C8 to C22) olefin and/or a (C8 to C22) secondary alcohol, optionally containing a primary alcohol, with a sulphating agent, b) neutralising the sulphation product comprising alkyl sulphuric acid and dialkyl sulphate produced in step a) with a base in aqueous solution, c) heating the product of step b) to saponify the dialkyl sulphate and to remove substantially all of the water from the mixture, d) cooling the product of step c) in the presence of a nonionic organic liquid diluent to ambient temperature whereby a crystallised solid composition separates, and e) recovering and drying the crystallised solid composition of step d), wherein the nonionic organic liquid diluent is added at some point prior to step d), characterized in that a zeolite is added in step c) and/or step d), and the surfactant composition so prepared.

Abstract translation: 一种制备包含仲（C 8 -C 22）烷基硫酸盐的表面活性剂组合物的方法，该方法包括：a）（C 8 -C 22）烯烃和/或（C 8至C 22）仲醇的硫酸化，任选地含有伯醇， 使用硫酸盐化剂，b）使碱在水溶液中与步骤a）中产生的包含烷基硫酸和二烷基硫酸盐的硫酸化产物中和，c）加热步骤b）的产物以皂化二烷基硫酸盐并将基本上全部的 来自混合物的水，d）在非离子有机液体稀释剂存在下将步骤c）的产物冷却至环境温度，由此结晶的固体组合物分离并e）回收和干燥步骤d）的结晶固体组合物，其中 在步骤d）之前的某一点加入非离子有机液体稀释剂，其特征在于在步骤c）和/或步骤d）中加入沸石，如此制备表面活性剂组合物。

公开(公告)号：WO1993024452A1

公开(公告)日：1993-12-09

申请号：PCT/EP1993001339

申请日：1993-05-26

Applicant: SHELL CANADA LIMITED ,  SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

Inventor： SHELL CANADA LIMITED ,  SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. ,  LUTZ, Eugene, Frederick ,  SCHISLA, David, Karl ,  TOMASKOVIC, Robert, Stephen ,  HOEWING, Timothy, Dee

IPC: C07C303/24

CPC classification number: C07C303/24 ,  C07C303/44 ,  C11D1/146 ,  C07C305/06

Abstract: This invention relates to a process for preparing a surfactant composition comprising a secondary (C8 to C22) alkyl sulfate, which process comprises: a) sulfating a (C8 to C22) olefin and/or a (C8 to C22) secondary alcohol, optionally containing a primary alcohol, with a sulfating agent, b) neutralizing the sulfation product comprising alkyl sulfuric acid and dialkyl sulfate produced in step a) with a base in aqueous solution, c) heating the product of step b) to saponify the dialkyl sulfate and to remove substantially all of the water from the mixture, followed by either d) cooling the product of step c) in the presence of a nonionic organic liquid diluent to ambient temperature whereby a crystallized solid composition separates, and e) recovering and drying the crystallized solid composition of step d), or by f) contacting and mixing the product of step c) with a glycol in the presence of a nonionic organic liquid diluent, g) phase separating the lower phase from the mixture formed in step f) which contains the glycol and the composition; and the surfactant composition so prepared.

Abstract translation: 本发明涉及一种制备包含仲（C 8 -C 22）烷基硫酸盐的表面活性剂组合物的方法，该方法包括：a）将（C 8至C 22）烯烃和/或（C 8至C 22）仲醇硫酸化，任选地包含 具有硫酸化剂的伯醇，b）将碱在水溶液中的步骤a）中产生的包含烷基硫酸和二烷基硫酸盐的硫酸化产物中和，c）加热步骤b）的产物以皂化二烷基硫酸盐，并将 从混合物中基本上除去所有的水，然后d）在非离子有机液体稀释剂存在下将步骤c）的产物冷却至环境温度，由此结晶的固体组合物分离，e）回收和干燥结晶的固体 步骤d）的组合物，或f）在非离子有机液体稀释剂存在下，将步骤c）的产物与二元醇接触和混合，g）将下层与形成的混合物相分离 n步骤f）其中含有二醇和组成; 和如此制备的表面活性剂组合物。