OXIME DERIVATIVES AND THE USE THEROF AS LATENT ACIDS
    1.
    发明申请
    OXIME DERIVATIVES AND THE USE THEROF AS LATENT ACIDS 审中-公开
    OXIME衍生物及其作为有用的酸的用途

    公开(公告)号:WO2006008250A2

    公开(公告)日:2006-01-26

    申请号:PCT/EP2005/053296

    申请日:2005-07-11

    IPC分类号: C07C309/65

    摘要: The invention pertain to novel photoacid generator compounds of the formula (I, II or III), Wherein R 1 is for example C 1 -C 18 alkylsulfonyl or phenylsulfonyl, phenyl-C 1 -C 3 alkylsulfonyl, , naphthylsulfonyl, anthracylsulfonyl or phenanthrylsulfonyl, all optionally substituted, or R 1 is a group (a, b or c); X 1 , X 2 and X 3 independently of each other are O or S; R' 1 is e.g. phenylenedisulfonyl, naphthylenedisulfonyl, diphenylenedisulfonyl, or oxydiphenylenedisulfonyl, all optionally substituted; R 2 is halogen or C 1 -C 10 haloalkyl; X is halogen; Ar 1 is for example biphenylyl or fluorenyl, or is substituted naphthyl; Ar' 1 is heteroarylene, optionally substituted; R 8 , R 9 , R 10 and R 11 for example are C 1 -C 6 alkyl which is unsubstituted or substituted by halogen; or R 8 , R 9 and R 10 are phenyl which is unsubstituted or substituted by C 1 -C 4 alkyl or halogen; or R 10 and R 11 together are 1,2-phenylene or C 2 -C 6 alkylene which is unsubstituted or substituted by C 1 -C 4 alkyl or halogen.

    摘要翻译: 本发明涉及式(I,II或III)的新型光致酸产生剂化合物,其中R 1是例如C 1 -C 18 烷基磺酰基或苯基磺酰基,苯基-C 1 -C 3烷基磺酰基,全部任意取代的萘磺酰基,蒽磺酰基或菲基磺酰基,或R 1是 一组(a,b或c); X 1,X 2和X 3彼此独立地为O或S; R 1'是例如。 亚苯基二磺酰基,亚苯基二磺酰基,二苯基二磺酰基或氧基二苯基二磺酰基,全部任选被取代; R 2是卤素或C 1 -C 10卤代烷基; X是卤素; Ar 1是例如联苯基或芴基,或者是取代的萘基; Ar'1'是亚杂芳基,任选被取代; R 8,R 9,R 10和R 11是例如C 1〜N 未取代或被卤素取代的C 1 -C 6烷基; 或R 8,R 9和R 10是未被取代或被C 1 -C 3烷基取代的苯基, 烷基或卤素; 或R 10和R 11一起是1,2-亚苯基或C 2 -C 6 -C 6亚烷基,其是 未取代或被C 1 -C 4烷基或卤素取代。

    ALCOHOL-ESTER SEPARATION BY RECRYSTALLIZATION
    2.
    发明申请
    ALCOHOL-ESTER SEPARATION BY RECRYSTALLIZATION 审中-公开
    酒精分离由重结晶

    公开(公告)号:WO1991015472A1

    公开(公告)日:1991-10-17

    申请号:PCT/US1991002114

    申请日:1991-03-28

    IPC分类号: C07C309/73

    摘要: A process is disclosed for the separation of an enantiomerically enriched 1-tosyloxy-2-acyloxy-3-butene and an enantiomerically enriched 1-tosyloxy-2-hydroxy-3-butene from a first mixture containing both compounds. The process includes the steps of: (a) forming a solution of the mixture in an organic solvent; (b) bringing the solution formed in (a) to a temperature wherein most of the enantiomerically enriched 1-tosyloxy-2-hydroxy-3-butene precipitates, leaving in solution most of the enantiomerically enriched 1-tosyloxy-2-acyloxy-3-butene; and (c) separating the precipitate formed in (b) from the solution.

    摘要翻译: 公开了从含有两种化合物的第一混合物分离对映体富集的1-甲氧基-2-酰氧基-3-丁烯和对映体富集的1-甲苯氧基-2-羟基-3-丁烯的方法。 该方法包括以下步骤:(a)在有机溶剂中形成混合物的溶液; (b)使(a)中形成的溶液达到大部分对映体富集的1-甲氧基-2-羟基-3-丁烯沉淀的温度,在溶液中留下大部分对映异构体富集的1-甲氧基-2-酰氧基-3 丁烯; 和(c)将(b)中形成的沉淀物与溶液分离。

    METHOD AND AGENT FOR DETERMINING AN ENZYMATIC ACTIVITY SUCH AS DEAMINASE
    7.
    发明申请
    METHOD AND AGENT FOR DETERMINING AN ENZYMATIC ACTIVITY SUCH AS DEAMINASE 审中-公开
    用于测定酶活性的方法和试剂如杀虫剂

    公开(公告)号:WO99024604A1

    公开(公告)日:1999-05-20

    申请号:PCT/FR1998/002380

    申请日:1998-11-06

    摘要: The invention concerns a method for detecting and identifying and/or quantifying an enzymatic activity such as deaminase of a micro-organism, which consists in contacting an inoculum capable of containing a micro-organism with a deaminase activity with a culture medium for micro-organisms. The invention is characterised in that the culture medium comprises at least a detecting agent for determining, by forming a coloured product with a colour reagent, an enzymatic activity such as deaminase, said detecting agent comprising at least one compound of general formula (I): said detecting agent is an L-amino acid of general formula (I) in which R represents a cyclic amino acid radical, substituted by 1 to 3 groups X, identical or different; X represents a group limiting diffusion of alpha -keto acid produced by the deamination of the cyclic amino acid; the compound of formula (I) capable of being substituted by different groups not interfering with the function of group X. The invention also concerns a detection agent and a culture medium comprising at least a detecting agent.

    摘要翻译: 本发明涉及用于检测和/或定量酶活性的方法,例如微生物的脱氨酶,其包括将能含有微生物的接种物与脱氨酶活性与微生物培养基接触 。 本发明的特征在于,所述培养基至少包含用于通过与着色试剂形成着色产物来测定酶活性如脱氨酶的检测剂,所述检测剂包含至少一种通式(I)的化合物: 所述检测剂是通式(I)的L-氨基酸,其中R表示相同或不同的1〜3个X基团取代的环状氨基酸基团; X表示限制由环状氨基酸脱氨生成的α-酮酸扩散的基团; 能够被不影响组X的功能的不同基团取代的式(I)化合物。本发明还涉及至少包含检测剂的检测剂和培养基。

    PROTECTED HYDROXY METHOD FOR ALCOHOL-ESTER SEPARATION
    8.
    发明申请
    PROTECTED HYDROXY METHOD FOR ALCOHOL-ESTER SEPARATION 审中-公开
    用于酒精分离的保护性羟基方法

    公开(公告)号:WO1991015471A1

    公开(公告)日:1991-10-17

    申请号:PCT/US1991002113

    申请日:1991-03-28

    IPC分类号: C07C309/73

    摘要: A process is disclosed for the isolation of an enantiomerically enriched alcohol from a first mixture of an enantiomerically enriched alcohol and an enantiomerically enriched ester. The process includes the steps of: (a) contacting the mixture with a reagent capable of reacting with the hydroxy function of the alcohol, without the loss of optical purity, so as to produce a second mixture containing a base-stable derivative of the enantiomerically enriched alcohol and the unreacted ester; (b) contacting the second mixture with a base capable of reacting with the ester so as to produce a third mixture containing a compound more volatile than the base-stable derivative of the alcohol; (c) removing the volatile compound from the third mixture; and (d) converting the base-stable derivative of the alcohol back to the enantiomerically enriched alcohol, without the loss of optical purity.

    摘要翻译: 公开了从对映体富集的醇和对映异构体富集的酯的第一混合物中分离对映体富集的醇的方法。 该方法包括以下步骤:(a)使混合物与能够与醇的羟基官能团反应的试剂接触,而不损失光学纯度,从而产生含有对映异构体的碱稳定衍生物的第二混合物 富醇和未反应的酯; (b)使第二混合物与能够与酯反应的碱接触,以产生含有比醇稳定的碱稳定的衍生物更易挥发的化合物的第三混合物; (c)从第三混合物中除去挥发性化合物; 和(d)将醇的碱稳定衍生物转化为对映体富集的醇,而不会损失光学纯度。