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    SYNTHESIS OF 4-AMINO-PYRIMIDINES
    6.
    发明申请
    SYNTHESIS OF 4-AMINO-PYRIMIDINES 审中-公开
    4-氨基吡啶的合成

    公开(公告)号：WO2008087021A1

    公开(公告)日：2008-07-24

    申请号：PCT/EP2008/000320

    申请日：2008-01-17

    Applicant: DSM IP ASSETS B.V. ,  BONRATH, Werner ,  HAERTER, Ralph ,  KARGE, Reinhard ,  LETINOIS, Ulla

    Inventor： BONRATH, Werner ,  HAERTER, Ralph ,  KARGE, Reinhard ,  LETINOIS, Ulla

    IPC: C07D239/42

    CPC classification number: C07D239/42

    Abstract: Process for the manufacture of a compound of the structure (I) with R 1 = hydrogen, alkyl (C1 - C10, linear, cyclic or branched, aliphatic or aromatic), NR'R" (wherein R' and R" are independently selected from H, alkyl [C1 - C10, linear, cyclic or branched, aliphatic or aromatic] and R 2 = CH 2 R 3 wherein R 3 is selected from NHR1"' (with R"' = C(O)H, C(O)CH 3 , C(O)alkyl, CH 2 C 6 H 2 (OMe) 3 or other saponifiable residues), alkyl (C1 - C10, linear, cyclic or branched) aromatic residues, heteroaryl residues, substituted aryl residues, e. g. 3,4,5-trimethoxy-phenyl) wherein 1 equivalent of an α-formyl-propionitrile salt is reacted with 0.75 to 2 equivalents of an acetamidine salt in the presence of a Lewis acid.

    Abstract translation: 制备具有R 1 =氢的结构（I）的化合物的方法，（C1-C10，直链，环状或支链，脂族或芳族）烷基，NR'R“（其中R '和R“独立地选自H，烷基[C1-C10，直链，环状或支链，脂族或芳族]和R 2 = CH 2 3其中R 3选自NHR 1“（R”'= C（O）H，C（O）CH 3 N，C（O ）烷基，CH 2 2 C 6 H 2（OMe）3或其它可皂化残基），烷基（C 1 -C 10，直链，环状或支链）芳族残基，杂芳基残基，取代的芳基残基，例如3,4,5-三甲氧基 - 苯基），其中1当量的α-甲酰基 - 丙腈盐与0.75-2当量的 乙脒盐在路易斯酸存在下反应。

    FORTIFICATION OF SUGAR CUBES
    7.
    发明申请
    FORTIFICATION OF SUGAR CUBES 审中-公开
    糖果的改良

    公开(公告)号：WO2011000827A1

    公开(公告)日：2011-01-06

    申请号：PCT/EP2010/059203

    申请日：2010-06-29

    Applicant: DSM IP Assets B.V. ,  STEIGER, Gearg

    Inventor： STEIGER, Gearg

    IPC: A23L1/00 ,  C13F3/00 ,  C13F5/00

    CPC classification number: C13B50/004 ,  A23L33/15 ,  A23P10/30 ,  A23V2002/00 ,  C13B40/007 ,  C13B50/002 ,  A23V2250/51 ,  A23V2250/5114 ,  A23V2250/702 ,  A23V2200/22 ,  A23V2250/628

    Abstract: Method for preparing sugar cubes comprising the step of adding a sugar pre-form consisting of crystal sugar particles comprising a sugar core which is coated with a mixture of one or more polysaccharides and/or one or more oligosaccharides said coating further containing a stabilized nutrient - preferably Vitamin A esters - to bulk sugar directly before the forming of sugar cubes; and sugar cubes so obtained.

    Abstract translation: 制备糖立方体的方法包括以下步骤：加入由结晶糖颗粒组成的糖预形成物，其包含糖核心，所述糖芯包被一种或多种多糖和/或一种或多种寡糖的混合物，所述寡糖和/或一种或多种寡糖的混合物进一步含有稳定的营养物 - 优选维生素A酯 - 直接形成糖立方体之前的散装糖; 和如此获得的糖立方体。

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