公开(公告)号：WO2009014259A1

公开(公告)日：2009-01-29

申请号：PCT/JP2008/063722

申请日：2008-07-24

Applicant: AJINOMOTO CO., INC. ,  SAMSONOV, Valery, Vasilievich ,  GORBACHEVA, Lubov, Yurievna ,  AKHVERDIAN, Valeriy, Zavenovich ,  VOROSHILOVA, Elvira, Borisovna

Inventor： SAMSONOV, Valery, Vasilievich ,  GORBACHEVA, Lubov, Yurievna ,  AKHVERDIAN, Valeriy, Zavenovich ,  VOROSHILOVA, Elvira, Borisovna

IPC: C12P13/08 ,  C07K14/245

CPC classification number: C12P13/222 ,  C07K14/245 ,  C12P13/04 ,  C12P13/06 ,  C12P13/08 ,  C12P13/10 ,  C12P13/12 ,  C12P13/14 ,  C12P13/20 ,  C12P13/225 ,  C12P13/227 ,  C12P13/24

Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea , which has been modified to attenuate expression of the yncD gene.

Abstract translation: 本发明提供了使用肠杆菌科的细菌，特别是属于埃希氏杆菌属或泛菌属的细菌来生产L-氨基酸的方法，其已被修饰以减弱yncD基因的表达。

公开(公告)号：WO2008096837A1

公开(公告)日：2008-08-14

申请号：PCT/JP2008/052092

申请日：2008-02-04

Applicant: AJINOMOTO CO., INC. ,  SAMSONOV, Valery, Vasilievich ,  KAPLAN, Alla, Markovna ,  AKHVERDIAN, Valeriy, Zavenovich ,  VOROSHILOVA, Elvira, Borisovna ,  GUSYATINER, Mikhail, Markovich

Inventor： SAMSONOV, Valery, Vasilievich ,  KAPLAN, Alla, Markovna ,  AKHVERDIAN, Valeriy, Zavenovich ,  VOROSHILOVA, Elvira, Borisovna ,  GUSYATINER, Mikhail, Markovich

IPC: C12P13/08 ,  C07K14/245

CPC classification number: C07K14/245 ,  C12P13/04 ,  C12P13/06 ,  C12P13/08 ,  C12P13/10 ,  C12P13/12 ,  C12P13/14 ,  C12P13/222 ,  C12P13/227 ,  C12P13/24

Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea , which has been modified to attenuate expression of the tolC gene.

Abstract translation: 本发明提供一种利用肠杆菌科的细菌，特别是属于埃希氏杆菌属或泛菌属的细菌来生产L-氨基酸的方法，该方法已被修饰以减弱tolC基因的表达。

公开(公告)号：WO2006043730A1

公开(公告)日：2006-04-27

申请号：PCT/JP2005/019840

申请日：2005-10-21

Applicant: AJINOMOTO CO., INC. ,  RYBAK, Konstantin, Vyacheslavovich ,  SLIVINSKAYA, Ekaterina, Aleksandrovna ,  SAVRASOVA, Ekaterina, Alekseevna ,  AKHVERDIAN, Valeriy, Zavenovich ,  KLYACHKO, Elena, Vitalievna ,  MASHKO, Sergei, Vladimirovich ,  DOROSHENKO, Vera, Georgievna ,  AIRIKH, Larisa, Gotlibovna ,  LEONOVA, Tatyana, Viktorovba ,  GUSYATINER, Mikhail, Markovich ,  VOROSHILOVA, Elvira, Borisovna ,  KOZLOV, Yury, Ivanovich ,  HARA, Yoshihiko ,  UEDA, Takuji

Inventor： RYBAK, Konstantin, Vyacheslavovich ,  SLIVINSKAYA, Ekaterina, Aleksandrovna ,  SAVRASOVA, Ekaterina, Alekseevna ,  AKHVERDIAN, Valeriy, Zavenovich ,  KLYACHKO, Elena, Vitalievna ,  MASHKO, Sergei, Vladimirovich ,  DOROSHENKO, Vera, Georgievna ,  AIRIKH, Larisa, Gotlibovna ,  LEONOVA, Tatyana, Viktorovba ,  GUSYATINER, Mikhail, Markovich ,  VOROSHILOVA, Elvira, Borisovna ,  KOZLOV, Yury, Ivanovich ,  HARA, Yoshihiko ,  UEDA, Takuji

IPC: C07K14/245 ,  C12P13/04

CPC classification number: C12P13/08 ,  C12P13/10 ,  C12P13/14 ,  C12P13/222 ,  C12P13/24

Abstract: There is disclosed a method for producing L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of D-xylose permease.

Abstract translation: 公开了使用肠杆菌科的细菌生产L-氨基酸的方法，例如L-苏氨酸，L-赖氨酸，L-组氨酸，L-苯丙氨酸，L-精氨酸或L-谷氨酸，其中细菌 已被修饰以增强D-木糖通透酶的活性。