公开(公告)号：WO2007122210A2

公开(公告)日：2007-11-01

申请号：PCT/EP2007/053940

申请日：2007-04-23

Applicant: DSM IP Assets B.V. ,  EDENS, Luppo ,  BECKHOVEN, VAN, Rudolf Franciscus Wilhelmus Cornelis ,  TABELING, Michael Dennis

Inventor： EDENS, Luppo ,  BECKHOVEN, VAN, Rudolf Franciscus Wilhelmus Cornelis ,  TABELING, Michael Dennis

IPC: C12N9/62 ,  A23J3/34 ,  C12P21/06 ,  C12C5/00

CPC classification number: C12N9/48 ,  A23J3/34 ,  A23L2/84 ,  C12C5/004 ,  C12N9/62

Abstract: The invention relates to a proline-specific protease preparation free from amylolytic activity and a purification method for obtaining the enzyme preparation according to the invention.

Abstract translation: 本发明涉及不含淀粉分解活性的脯氨酸特异性蛋白酶制剂和获得本发明酶制剂的纯化方法。

公开(公告)号：WO2003100048A1

公开(公告)日：2003-12-04

申请号：PCT/EP2003/005724

申请日：2003-05-28

Applicant: DSM IP ASSETS B.V. ,  BECKHOVEN, VAN, Rudolf, Franciscus, Wilhelmus, Cornelis ,  NAEYE, Thierry, Jean-Bernard

Inventor： BECKHOVEN, VAN, Rudolf, Franciscus, Wilhelmus, Cornelis ,  NAEYE, Thierry, Jean-Bernard

IPC: C12N9/58

CPC classification number: C07K1/20 ,  C07K1/22 ,  C12N9/58

Abstract: The invention disclose a method for purifying microbial protease, comprising:(i) providing an aqueous liquid sample containing a microbial protease, and a separation medium comprising a base matrix and a plurality of attached ligands that are capable of binding to microbial protease;(ii) contacting separation medium with the sample under conditions permitting binding of microbial protease to the separation medium; and (iii) desorbing microbial protease from the separation medium,wherein the base matrix is hydrophilic and the plurality of ligands are hydrocarbon groups in which all carbon atoms are sp3-hybridised.

Abstract translation: 本发明公开了一种纯化微生物蛋白酶的方法，包括：（i）提供含有微生物蛋白酶的水性液体样品，以及包含能够结合微生物蛋白酶的基础基质和多个连接的配体的分离培养基;（ii） ）使分离介质与样品在允许微生物蛋白酶与分离介质结合的条件下接触; 和（iii）从分离介质中解吸微生物蛋白酶，其中基础基质是亲水性的，并且多个配体是其中所有碳原子都被sp3杂交的烃基。

公开(公告)号：WO2002081673A1

公开(公告)日：2002-10-17

申请号：PCT/EP2002/003680

申请日：2002-04-03

Applicant: DSM N.V. ,  BECKHOVEN, VAN, Rudolf, Franciscus, Wilhelmus, Cornelis ,  PARIDON, VAN, Petrus, Andreas

Inventor： BECKHOVEN, VAN, Rudolf, Franciscus, Wilhelmus, Cornelis ,  PARIDON, VAN, Petrus, Andreas

IPC: C12N9/38

CPC classification number: A23C9/1206 ,  A23C2210/208 ,  C12N9/2402 ,  C12N9/2471 ,  C12Y302/01023 ,  C12Y302/01108

Abstract: The present invention relates to a lactase solution comprising a lactase solution comprising less than 10 g/kg of poly and oligosaccharides, a process for the production of such a lactase solution from an untreated lactase solution, a sterilized lactase solution and to a process for the production of milk containing sterilized lactase, whereby such lactose is filter sterilized in-line with the milk production process.

Abstract translation: 本发明涉及含有少于10g / kg聚低聚糖的乳糖酶溶液的乳糖酶溶液，从未处理的乳糖酶溶液生产这种乳糖酶溶液的方法，灭菌的乳糖酶溶液以及用于 生产含有灭菌乳糖酶的牛奶，由此将这种乳糖与牛奶生产过程一并过滤灭菌。

公开(公告)号：WO2008052995A1

公开(公告)日：2008-05-08

申请号：PCT/EP2007/061701

申请日：2007-10-30

Applicant: DSM IP ASSETS B.V. ,  ROOS, DE, Andre Leonardus ,  EDENS, Luppo ,  BECKHOVEN, VAN, Rudolf Franciscus Wilhelmus Cornelis ,  DUCHATEAU, Alexander Lucia Leonardus ,  KLOEK, Joris

Inventor： ROOS, DE, Andre Leonardus ,  EDENS, Luppo ,  BECKHOVEN, VAN, Rudolf Franciscus Wilhelmus Cornelis ,  DUCHATEAU, Alexander Lucia Leonardus ,  KLOEK, Joris

IPC: C12P21/06 ,  C12P13/22 ,  A61P1/14

CPC classification number: A61K38/06 ,  A23K20/147 ,  A23L33/18 ,  A61K38/05 ,  C12P13/22 ,  C12P21/06

Abstract: The present invention relates to a process to produce a composition comprising water-soluble peptides and having a Trp/LNAA ratio of more than 0.15, which comprises hydrolyzing lysozyme, preferably hen eggs lysozyme, to prepare a hydrolysate having a DH of between 5 and 45.

Abstract translation: 本发明涉及一种制备包含水溶性肽并且Trp / LNAA比大于0.15的组合物的方法，其包括水解溶菌酶，优选鸡蛋溶菌酶，以制备DH为5至45的水解产物 。