公开(公告)号：WO2005027753A1

公开(公告)日：2005-03-31

申请号：PCT/US2004/030678

申请日：2004-09-17

Applicant: ST. JUDE MEDICAL, INC. ,  BRENZEL, Michael P. ,  HINDRICHS, Paul J. ,  DALE, Theodore P. ,  KRINKE, Todd A. ,  KRUSE, Steven D. ,  COSTELLO, David M. ,  BERG, Todd A. ,  ROOP, John A.

Inventor： BRENZEL, Michael P. ,  HINDRICHS, Paul J. ,  DALE, Theodore P. ,  KRINKE, Todd A. ,  KRUSE, Steven D. ,  COSTELLO, David M. ,  BERG, Todd A. ,  ROOP, John A.

IPC: A61B17/00

CPC classification number: A61B17/1285 ,  A61B17/0057 ,  A61B17/1227 ,  A61B2017/00349 ,  A61B2017/00575

Abstract: Methods and apparatus are provided that gather a patient's body tissue and then secure the gathered tissue in a reduced area utilizing a securing structure. The securing structure mainly resides on one side of the tissue to minimize or eliminate both foreign material and the amount of manipulation or activity on the other side of the tissue. The securing device is matched to the desired amount of tissue manipulation to minimize the structure. The gathered and secured tissue can surround a septal defect to obstruct or close the defect itself.

Abstract translation: 提供了收集患者身体组织然后利用固定结构将聚集的组织固定在缩小区域中的方法和装置。 固定结构主要位于组织的一侧，以最小化或消除外来物质和组织另一侧的操作或活动量。 固定装置与所需的组织操作量匹配，以最小化结构。 收集和固定的组织可以围绕隔膜缺陷以阻碍或闭合缺陷本身。

公开(公告)号：WO2004082538A3

公开(公告)日：2004-04-14

申请号：PCT/US2004008341

申请日：2004-03-17

Applicant: ST JUDE MEDICAL ,  HINDRICHS PAUL J ,  KRUSE STEVEN D ,  KRINKE TODD A ,  BRENZEL MICHAEL P ,  QUEST MATTHEW M ,  ZEHR KENTON J ,  BERG TODD A ,  LOGAN JOHN ,  KUEHN STEPHEN T

Inventor： HINDRICHS PAUL J ,  KRUSE STEVEN D ,  KRINKE TODD A ,  BRENZEL MICHAEL P ,  QUEST MATTHEW M ,  ZEHR KENTON J ,  BERG TODD A ,  LOGAN JOHN ,  KUEHN STEPHEN T

IPC: A61B17/00 ,  A61B17/04 ,  A61B17/064 ,  A61B17/068 ,  A61F2/06 ,  A61F2/24 ,  A61F2/90

CPC classification number: A61F2/2451 ,  A61B17/00234 ,  A61B17/0401 ,  A61B17/0487 ,  A61B17/064 ,  A61B17/068 ,  A61B2017/00243 ,  A61B2017/00783 ,  A61B2017/0409 ,  A61B2017/0412 ,  A61B2017/0414 ,  A61B2017/0417 ,  A61B2017/0427 ,  A61B2017/0437 ,  A61B2017/0454 ,  A61B2017/0462 ,  A61B2017/0464 ,  A61B2017/0649 ,  A61F2/2487

Abstract: A patient's soft body tissue can be remodelled by implanting first and second anchor structures in the tissue at respective first and second spaced locations. Alinking structure between the anchor structures is then operated to change the distance between the first and second anchor structures. Examples of use are repair of a patient's mitral and/or tricuspid valve(s) and/or remodeling of a patient's left ventricle.

Abstract translation: 可以通过在相应的第一和第二间隔位置处将组织中的第一和第二锚固结构植入而改变病人的软体组织。 然后操作锚结构之间的分解结构以改变第一和第二锚结构之间的距离。 使用的实例是修复患者的二尖瓣和/或三尖瓣和/或重建患者的左心室。

公开(公告)号：WO02094132A8

公开(公告)日：2003-01-30

申请号：PCT/US0216956

申请日：2002-05-24

Applicant: BERG TODD A ,  BERG JAMES

Inventor： BERG TODD A ,  BERG JAMES

IPC: A61B17/00 ,  A61B17/064 ,  A61B17/068 ,  A61B17/072 ,  A61B17/115 ,  A61B17/12 ,  A61F2/00 ,  A61F2/04 ,  A61F2/24

CPC classification number: A61F2/2445 ,  A61B17/064 ,  A61B17/0682 ,  A61B17/072 ,  A61B17/115 ,  A61B2017/00557 ,  A61B2017/00827 ,  A61B2017/0647 ,  A61F2/04 ,  A61F2/91 ,  A61F2/958 ,  A61F2002/8483 ,  A61F2250/0039

Abstract: A self-retracting body, which may have a bore, may be inserted into a biological passage. A dilating balloon may be used to expand the body toward an inner wall of the passage. The body may include an anchor that may engage the wall. The anchor may include a tip that is within the body before the body expands and extends away from the body during expansion. The body may include an opening that may receive a portion of the wall. The portion may be fixed to the body. The body may retract toward a central portion of the passage after the anchor engages the wall. The wall may be drawn toward the central passage and the diameter of the passage may be reduced. In some embodiments, a liner may be provided for the passage. In some embodiments, a baffle may be provided for the passage.

公开(公告)号：WO2004082538A2

公开(公告)日：2004-09-30

申请号：PCT/US2004/008341

申请日：2004-03-17

Applicant: ST. JUDE MEDICAL, INC. ,  HINDRICHS, Paul, J. ,  KRUSE, Steven, D. ,  KRINKE, Todd, A. ,  BRENZEL, Michael, P. ,  QUEST, Matthew, M. ,  ZEHR, Kenton, J. ,  BERG, Todd, A. ,  LOGAN, John ,  KUEHN, Stephen, T.

Inventor： HINDRICHS, Paul, J. ,  KRUSE, Steven, D. ,  KRINKE, Todd, A. ,  BRENZEL, Michael, P. ,  QUEST, Matthew, M. ,  ZEHR, Kenton, J. ,  BERG, Todd, A. ,  LOGAN, John ,  KUEHN, Stephen, T.

IPC: A61F2/24

CPC classification number: A61F2/2451 ,  A61B17/00234 ,  A61B17/0401 ,  A61B17/0487 ,  A61B17/064 ,  A61B17/068 ,  A61B2017/00243 ,  A61B2017/00783 ,  A61B2017/0409 ,  A61B2017/0412 ,  A61B2017/0414 ,  A61B2017/0417 ,  A61B2017/0427 ,  A61B2017/0437 ,  A61B2017/0454 ,  A61B2017/0462 ,  A61B2017/0464 ,  A61B2017/0649 ,  A61F2/2487

Abstract: A patient's soft body tissue can be remodelled by implanting first and second anchor structures in the tissue at respective first and second spaced locations. Alinking structure between the anchor structures is then operated to change the distance between the first and second anchor structures. Examples of use are repair of a patient's mitral and/or tricuspid valve(s) and/or remodeling of a patient's left ventricle.

Abstract translation: 可以通过在相应的第一和第二间隔位置处将组织中的第一和第二锚固结构植入而改变病人的软体组织。 然后操作锚结构之间的分解结构以改变第一和第二锚结构之间的距离。 使用的实例是修复患者的二尖瓣和/或三尖瓣和/或重建患者的左心室。

公开(公告)号：WO2006020382A1

公开(公告)日：2006-02-23

申请号：PCT/US2005/026469

申请日：2005-07-26

Applicant: TORAX MEDICAL, INC. ,  KUGLER, Chad J. ,  GRUDEM, Jerome K., Jr. ,  BERG, Todd A. ,  SWANSON, William J.

Inventor： KUGLER, Chad J. ,  GRUDEM, Jerome K., Jr. ,  BERG, Todd A. ,  SWANSON, William J.

IPC: A61F2/00

CPC classification number: A61B17/12009 ,  A61B17/12013 ,  A61B2017/00827 ,  A61B2017/00876 ,  A61B2017/12018 ,  A61F2/0036 ,  A61F5/005 ,  A61F5/0069

Abstract: A plurality of structures (20) that resiliently attract one another are provided for implanting in a patient around a body tissue structure of the patient. For example, the body tissue structure may be the esophagus, and the plurality of structures may be implanted in an annulus around the outside of the esophagus, the annulus being substantially coaxial with the esophagus. The attraction may be between annularly adjacent ones of the structures in the annulus, and it may be provided, for example, by magnets or springs. The array of structures is preferably self-limiting with respect to the smallest area that it can encompass, and this smallest area is preferably large enough to prevent the apparatus from applying excessive pressure to tissue passing through that area.

Abstract translation: 提供弹性地彼此吸引的多个结构（20），用于植入患者身体组织结构周围的患者体内。 例如，身体组织结构可以是食管，并且多个结构可以被植入食管外部周围的环状物中，该环状物与食管基本上同轴。 吸引力可以在环形结构中环形相邻的结构之间，并且其可以例如由磁体或弹簧提供。 该结构阵列相对于其可包含的最小区域优选是自限性的，并且该最小区域优选足够大以防止该装置向通过该区域的组织施加过大的压力。

公开(公告)号：WO2005082279A1

公开(公告)日：2005-09-09

申请号：PCT/US2005/005826

申请日：2005-02-23

Applicant: TORAX MEDICAL, INC. ,  KUGLER, Chad, J. ,  GRUDEM, Jerome, K., Jr. ,  BERG, Todd, A.

Inventor： KUGLER, Chad, J. ,  GRUDEM, Jerome, K., Jr. ,  BERG, Todd, A.

IPC: A61F2/02

CPC classification number: A61F2/02 ,  A61B17/0401 ,  A61B17/0469 ,  A61B17/0644 ,  A61B17/12022 ,  A61B17/12099 ,  A61B17/12131 ,  A61B2017/00818 ,  A61B2017/00827 ,  A61B2017/00876 ,  A61B2017/00893 ,  A61B2017/0419 ,  A61B2017/0641 ,  A61F2/04 ,  A61F2002/044 ,  A61F2210/009 ,  A61F2220/0016 ,  A61F2250/0067 ,  A61N2/06

Abstract: Implantable devices for use in a non-sterile environment of a patient's anatomy are medicated or include medication. For example, the housing of the device and/or members for securing the device to the pateint's anatomy (e.g., the muscular esophageal wall) may be medicated to, among other things, prevent a rejection mechanism from being triggered, to prevent or reduce bacterial infection, or to promote tissue ingrowth. The medication may be for medicating tissue at the implant site, or for medicating some other portion of the patient's anatomy.

Abstract translation: 用于患者解剖结构的非无菌环境的植入式装置被药物化或包括药物治疗。 例如，用于将装置固定到便利解剖结构（例如，肌肉食管壁）的装置和/或构件的壳体可被用于防止被排除机制被触发，以防止或减少细菌 感染或促进组织向内生长。 药物可以是用于在植入部位处理组织，或用于治疗患者解剖结构的某些其他部分。

公开(公告)号：WO2002094132A2

公开(公告)日：2002-11-28

申请号：PCT/US2002/016956

申请日：2002-05-24

Applicant: BERG, Todd, A. ,  BERG, James

Inventor： BERG, Todd, A. ,  BERG, James

IPC: A61F2/00

CPC classification number: A61F2/2445 ,  A61B17/064 ,  A61B17/0682 ,  A61B17/072 ,  A61B17/115 ,  A61B2017/00557 ,  A61B2017/00827 ,  A61B2017/0647 ,  A61F2/04 ,  A61F2/91 ,  A61F2/958 ,  A61F2002/8483 ,  A61F2250/0039

Abstract: A self-retracting body, which may have a bore, may be inserted into a biological passage. A dilating balloon may be used to expand the body toward an inner wall of the passage. The body may include an anchor that may engage the wall. The anchor may include a tip that is within the body before the body expands and extends away from the body during expansion. The body may include an opening that may receive a portion of the wall. The portion may be fixed to the body. The body may retract toward a central portion of the passage after the anchor engages the wall. The wall may be drawn toward the central passage and the diameter of the passage may be reduced. In some embodiments, a liner may be provided for the passage. In some embodiments, a baffle may be provided for the passage.

Abstract translation: 可以具有孔的自回缩体可插入生物通道中。 可以使用扩张气囊来朝向通道的内壁扩张身体。 主体可以包括可以接合壁的锚。 锚固体可以包括在体部膨胀之前在体内的尖端，并且在膨胀期间远离身体延伸。 主体可以包括可以接收壁的一部分的开口。 该部分可以固定在身体上。 在锚固器接合墙壁之后，主体可以朝向通道的中心部分缩回。 可以将壁拉向中央通道并且可以减小通道的直径。 在一些实施例中，可以为通道提供衬垫。 在一些实施例中，可以为通道提供挡板。

公开(公告)号：WO2009029228A3

公开(公告)日：2009-03-05

申请号：PCT/US2008/010019

申请日：2008-08-22

Applicant: TORAX MEDICAL, INC. ,  BERG, Todd A. ,  KRUSE, Steven D. ,  GRUDEM, JR., Jerome K. ,  ST. GERMAIN, Jon ,  STAINBROOK, Eric

Inventor： BERG, Todd A. ,  KRUSE, Steven D. ,  GRUDEM, JR., Jerome K. ,  ST. GERMAIN, Jon ,  STAINBROOK, Eric

IPC: A61F2/00

Abstract: A structure, that can be used as a gastric band (and that may also have other uses as an implant elsewhere in a patient) includes a plurality of magnetic elements (20) in a serial array that can be implanted so that the array extends in a circumferential direction around the patient's stomach (or other body tissue structure (30) in the patient). Circumferentially adjacent magnetic elements magnetically attract one another to apply radial pressure to the tissue structure encompassed by the array, but those elements can also move apart in response to sufficient outward pressure from the encompassed tissue structure and/or the contents of (e.g., food in) that tissue structure. When used as a gastric band, the device can provide resistance to excessive food intake, which can help promote weight loss.

公开(公告)号：WO2009029228A2

公开(公告)日：2009-03-05

申请号：PCT/US2008010019

申请日：2008-08-22

Applicant: TORAX MEDICAL INC ,  BERG TODD A ,  KRUSE STEVEN D ,  GRUDEM JR JEROME K ,  ST GERMAIN JON ,  STAINBROOK ERIC

Inventor： BERG TODD A ,  KRUSE STEVEN D ,  GRUDEM JR JEROME K ,  ST GERMAIN JON ,  STAINBROOK ERIC

IPC: A61F2/00

CPC classification number: A61F5/005 ,  A61B2017/00818 ,  A61B2017/00876 ,  A61F2/0018 ,  A61F2/0036 ,  A61F5/0066 ,  A61F2210/009

Abstract: A structure that can be used as a gastric band (and that may also have other uses as an implant elsewhere in a patient) includes a plurality of magnetic elements in a serial array that can be implanted so that the array extends in a circumferential direction around the patient's stomach (or other body tissue structure in the patient). Circumferentially adjacent magnetic elements magnetically attract one another to apply radial pressure to the tissue structure encompassed by the array, but those elements can also move apart in response to sufficient outward pressure from the encompassed tissue structure and/or the contents of (e.g., food in) that tissue structure. When used as a gastric band, the device can provide resistance to excessive food intake, which can help promote weight loss.

Abstract translation: 可以用作胃带（并且还可以作为其他用途在医院其他地方的其他用途）的结构包括可以植入的串联阵列中的多个磁性元件，使得阵列沿圆周方向延伸 患者的胃（或患者的其他身体组织结构）。 周向相邻的磁性元件相互磁吸引，以向阵列所包围的组织结构施加径向压力，但是这些元件也可以响应于来自包围的组织结构的足够的向外压力和/或（例如， ）组织结构。 当用作胃带时，该装置可以提供抵抗过量食物摄取，这可以帮助促进减肥。

公开(公告)号：WO2006020382A9

公开(公告)日：2006-04-27

申请号：PCT/US2005026469

申请日：2005-07-26

Applicant: TORAX MEDICAL INC ,  KUGLER CHAD J ,  GRUDEM JEROME K JR ,  BERG TODD A ,  SWANSON WILLIAM J

Inventor： KUGLER CHAD J ,  GRUDEM JEROME K JR ,  BERG TODD A ,  SWANSON WILLIAM J

IPC: A61F2/00 ,  A61B17/12 ,  A61F2/04

CPC classification number: A61B17/12009 ,  A61B17/12013 ,  A61B2017/00827 ,  A61B2017/00876 ,  A61B2017/12018 ,  A61F2/0036 ,  A61F5/005 ,  A61F5/0069

Abstract: A plurality of structures (20) that resiliently attract one another are provided for implanting in a patient around a body tissue structure of the patient. For example, the body tissue structure may be the esophagus, and the plurality of structures may be implanted in an annulus around the outside of the esophagus, the annulus being substantially coaxial with the esophagus. The attraction may be between annularly adjacent ones of the structures in the annulus, and it may be provided, for example, by magnets or springs. The array of structures is preferably self-limiting with respect to the smallest area that it can encompass, and this smallest area is preferably large enough to prevent the apparatus from applying excessive pressure to tissue passing through that area.

Abstract translation: 提供弹性地彼此吸引的多个结构（20），用于将患者周围的身体组织结构植入患者体内。 例如，身体组织结构可以是食道，并且多个结构可以被植入在食道外部的环形区域中，环形空间与食道基本上同轴。 吸引物可以在环形结构中的环形相邻结构之间，并且其可以例如由磁体或弹簧提供。 结构的阵列优选地相对于其可以包围的最小面积是自限制的，并且该最小面积优选地足够大以防止装置对通过该区域的组织施加过大的压力。