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    IMPLANTABLE INTEGRATED CIRCUIT
    1.
    发明申请
    IMPLANTABLE INTEGRATED CIRCUIT 审中-公开
    可嵌入式集成电路

    公开(公告)号：WO2007075974A2

    公开(公告)日：2007-07-05

    申请号：PCT/US2006048944

    申请日：2006-12-22

    Applicant: PROTEUS BIOMEDICAL INC ,  ZDEBLICK MARK ,  LEICHNER ROBERT ,  ARIA BEHARD ,  JANI NILAY ,  LI HAIFENG ,  THOMPSON TODD ,  ARNE LAWRENCE ,  ROBERTSON TIMOTHY ,  BI YAFEI ,  GELFANDBEIN VLADIMIER

    Inventor： ZDEBLICK MARK ,  LEICHNER ROBERT ,  ARIA BEHARD ,  JANI NILAY ,  LI HAIFENG ,  THOMPSON TODD ,  ARNE LAWRENCE ,  ROBERTSON TIMOTHY ,  BI YAFEI ,  GELFANDBEIN VLADIMIER

    IPC: A61N1/00

    CPC classification number: A61N1/056 ,  A61B5/0422 ,  A61N1/025 ,  A61N1/362 ,  A61N1/3686 ,  A61N1/372 ,  A61N1/37205 ,  A61N1/37276 ,  A61N1/37288 ,  A61N1/3756

    Abstract: Embodiments of the present invention enable robust, reliable control functionality for effectors present on intraluminal, e.g., vascular leads, as well as other types of implantable devices. Embodiments of the invention enable the required functionality for accurate long term control of effectors units, even ones present on multiplex carrier configurations, while provide for low power consumption. Aspects of the invention include implantable integrated circuits that have power extraction; energy storage; communication; and device configuration functional blocks, where these functional blocks are all present in a single integrated circuit on an intraluminal-sized support. Also provided by the invention are effector assemblies that include the integrated circuits, as well as implantable medical devices, e.g., pulse generators that include the same, as well as systems and kits thereof and methods of using the same, e.g., in pacing applications, including cardiac resynchronization therapy (CRT) applications.

    Abstract translation: 本发明的实施例对存在于管腔内（例如血管引线）以及其它类型的可植入装置的效果器提供了鲁棒，可靠的控制功能。 本发明的实施例能够实现对效果器单元的准确的长期控制所需的功能，即使存在于多路载波配置上的单元也能提供低功耗。 本发明的方面包括具有功率提取的可植入集成电路; 储能; 通讯; 以及器件配置功能块，其中这些功能块都存在于腔内尺寸支持体上的单个集成电路中。 本发明还提供了包括集成电路的效应器组件以及可植入的医疗装置，例如包括其的脉冲发生器，以及其系统和套件，以及使用该装置的方法，例如在起搏应用中， 包括心脏再同步治疗（CRT）应用。

    POWER MANAGEMENT FOR INTEGRATED TOUCH SCREENS
    3.
    发明申请
    POWER MANAGEMENT FOR INTEGRATED TOUCH SCREENS 审中-公开
    集成触摸屏电源管理

    公开(公告)号：WO2013043337A1

    公开(公告)日：2013-03-28

    申请号：PCT/US2012/052934

    申请日：2012-08-29

    Applicant: APPLE INC. ,  KRAH, Christoph, Horst ,  WHITE, Kevin, J. ,  BI, Yafei

    Inventor： KRAH, Christoph, Horst ,  WHITE, Kevin, J. ,  BI, Yafei

    IPC: G06F3/041 ,  G06F3/044

    CPC classification number: G06F3/0412 ,  G06F3/0418 ,  G06F3/044

    Abstract: Reducing or eliminating the effects of noise that can be generated by a power system of a touch screen device, such as a gate line voltage system that applies voltage to gate lines of the touch screen, is provided. In one example, a power supply, such as a charge pump, can be disabled during active touch sensing, such that noise from the charge pump is not generated during touch sensing. In some examples, a voltage regulator can help to maintain the gate voltage level at or above a desired threshold. In some cases, noise entering the touch sensing system can have a lasting effect on noise- sensitive components, even after the noise source is disabled. In these cases, a post-noise stabilizing system can be included to stabilize, reset, etc., noise-sensitive components of the touch sensing system, which can help to reduce or eliminate the lasting effect of noise.

    Abstract translation: 提供了减少或消除由触摸屏装置的电力系统产生的噪声的影响，诸如对触摸屏的栅极线施加电压的栅极线电压系统。 在一个示例中，可以在主动触摸感测期间禁用诸如电荷泵的电源，使得在触摸感测期间不产生来自电荷泵的噪声。 在一些示例中，电压调节器可以帮助将栅极电压电平维持在等于或高于所需阈值。 在某些情况下，甚至在噪声源被禁用之后，进入触摸感应系统的噪声也会对噪声敏感元件产生持久的影响。 在这些情况下，可以包括一个噪声后稳定系统来稳定，复位等触摸感应系统的噪声敏感部件，这有助于减少或消除噪音的持久影响。

    SELF-REFERENCING COMMUNICATION IN IMPLANTABLE DEVICES
    4.
    发明申请
    SELF-REFERENCING COMMUNICATION IN IMPLANTABLE DEVICES 审中-公开
    可插入设备中的自助通信

    公开(公告)号：WO2009029894A1

    公开(公告)日：2009-03-05

    申请号：PCT/US2008/074922

    申请日：2008-08-29

    Applicant: PROTEUS BIOMEDICAL, INC. ,  LI, Haifeng ,  ZDEBLICK, Mark J. ,  ARNE, Lawrence ,  BI, Yafei ,  JANI, Nilay ,  WITHRIGHTON, Jonathan

    Inventor： LI, Haifeng ,  ZDEBLICK, Mark J. ,  ARNE, Lawrence ,  BI, Yafei ,  JANI, Nilay ,  WITHRIGHTON, Jonathan

    IPC: A61N1/08

    CPC classification number: A61N1/37288 ,  A61N1/025

    Abstract: Various aspects of the present invention enable robust, reliable control functionality for effectors present on intraluminal, e.g., vascular leads, as well as other types of implantable devices. Aspects of the invention include implantable integrated circuits that have self-referencing and self-clocking signal encoding, and are capable of bidirectional communication. Also provided by the invention are effector assemblies that include the integrated circuits, as well as implantable medical devices, e.g., pulse generators that include the same, as well as systems and kits thereof and methods of using the same, e.g., in pacing applications, including cardiac resynchronization therapy (CRT) applications.

    Abstract translation: 本发明的各个方面对存在于管腔内（例如血管引线）以及其它类型的可植入装置的效果器提供了鲁棒且可靠的控制功能。 本发明的方面包括具有自参考和自时钟信号编码并且能够进行双向通信的可植入集成电路。 本发明还提供了包括集成电路的效应器组件以及可植入的医疗装置，例如包括其的脉冲发生器，以及其系统和套件，以及使用它们的方法，例如在起搏应用中， 包括心脏再同步治疗（CRT）应用。

    INTEGRATED CIRCUIT IMPLEMENTATION AND FAULT CONTROL SYSTEM, DEVICE, AND METHOD
    5.
    发明申请
    INTEGRATED CIRCUIT IMPLEMENTATION AND FAULT CONTROL SYSTEM, DEVICE, AND METHOD 审中-公开
    集成电路实现和故障控制系统，设备和方法

    公开(公告)号：WO2009131749A3

    公开(公告)日：2010-01-07

    申请号：PCT/US2009035586

    申请日：2009-02-27

    Applicant: PROTEUS BIOMEDICAL INC ,  BI YAFEI ,  LI HAIFENG ,  ZDEBLICK MARK ,  THOMPSON TODD ,  LEICHNER ROBERT

    Inventor： BI YAFEI ,  LI HAIFENG ,  ZDEBLICK MARK ,  THOMPSON TODD ,  LEICHNER ROBERT

    IPC: A61N1/372 ,  A61N1/36 ,  A61N1/365 ,  A61N1/375 ,  A61N1/378

    CPC classification number: A61N1/05 ,  A61N1/025 ,  A61N1/37 ,  A61N1/378

    Abstract: Apparatus and methods enable robust, reliable control for implantable medical devices, including cardiac pacemakers, defibrillators and cardiac resynchronization devices. Integrated circuits in the devices have minimized interfaces, can derive power from the interface signals, and have high voltage and latch-up protection. A device lead has a power generation circuit and a switching circuit using cascaded PMOS transistors for operating with a stable voltage despite fluctuations in the supplied voltage. The lead has control electronics that provide a very low impedance between an electrode and a lead conductor during most of the duration of a pacing pulse, but during a brief initial portion of the pacing pulse, provide a very high impedance to permit charging up a power supply that is local to the control electronics. A method of stabilizing the external impedance and a system for fault detection and fault recovery for an implantable device are also provided.

    Abstract translation: 装置和方法能够对可植入医疗装置（包括心脏起搏器，除颤器和心脏再同步装置）进行可靠的，可靠的控制。 器件中的集成电路具有最小化的接口，可以从接口信号中获取功率，并具有高电压和闭锁保护。 器件引线具有发电电路和使用级联PMOS晶体管的开关电路，用于尽管工作电压的波动，以稳定的电压工作。 引线具有控制电子学，其在起搏脉冲的大部分持续时间期间在电极和引线导体之间提供非常低的阻抗，但是在起搏脉冲的短暂初始部分期间，提供非常高的阻抗以允许充电电力 供应是本地控制电子产品。 还提供了稳定外部阻抗的方法和用于可植入装置的故障检测和故障恢复的系统。

    INTEGRATED CIRCUIT IMPLEMENTATION AND FAULT CONTROL SYSTEM, DEVICE, AND METHOD
    8.
    发明申请
    INTEGRATED CIRCUIT IMPLEMENTATION AND FAULT CONTROL SYSTEM, DEVICE, AND METHOD 审中-公开
    集成电路实现和故障控制系统，设备和方法

    公开(公告)号：WO2009131749A2

    公开(公告)日：2009-10-29

    申请号：PCT/US2009/035586

    申请日：2009-02-27

    Applicant: PROTEUS BIOMEDICAL, INC. ,  BI, Yafei ,  LI, Haifeng ,  ZDEBLICK, Mark ,  THOMPSON, Todd ,  LEICHNER, Robert

    Inventor： BI, Yafei ,  LI, Haifeng ,  ZDEBLICK, Mark ,  THOMPSON, Todd ,  LEICHNER, Robert

    CPC classification number: A61N1/05 ,  A61N1/025 ,  A61N1/37 ,  A61N1/378

    Abstract: Apparatus and methods enable robust, reliable control for implantable medical devices, including cardiac pacemakers, defibrillators and cardiac resynchronization devices. Integrated circuits in the devices have minimized interfaces, can derive power from the interface signals, and have high voltage and latch-up protection. A device lead has a power generation circuit and a switching circuit using cascaded PMOS transistors for operating with a stable voltage despite fluctuations in the supplied voltage. The lead has control electronics that provide a very low impedance between an electrode and a lead conductor during most of the duration of a pacing pulse, but during a brief initial portion of the pacing pulse, provide a very high impedance to permit charging up a power supply that is local to the control electronics. A method of stabilizing the external impedance and a system for fault detection and fault recovery for an implantable device are also provided.

    Abstract translation: 装置和方法能够对可植入医疗装置（包括心脏起搏器，除颤器和心脏再同步装置）进行可靠的，可靠的控制。 器件中的集成电路具有最小化的接口，可以从接口信号中获取功率，并具有高电压和闭锁保护。 器件引线具有发电电路和使用级联PMOS晶体管的开关电路，用于尽管工作电压的波动，以稳定的电压工作。 引线具有控制电子学，其在起搏脉冲的大部分持续时间期间在电极和引线导体之间提供非常低的阻抗，但是在起搏脉冲的短暂初始部分期间，提供非常高的阻抗以允许充电电力 供应是本地控制电子产品。 还提供了稳定外部阻抗的方法和用于可植入装置的故障检测和故障恢复的系统。

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