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    METHODS FOR REDUCING BODY FAT USING VITAMIN D COMPOUNDS
    1.
    发明申请
    METHODS FOR REDUCING BODY FAT USING VITAMIN D COMPOUNDS 审中-公开
    使用维生素D化合物降低身体脂肪的方法

    公开(公告)号：WO2005051396A3

    公开(公告)日：2005-11-17

    申请号：PCT/US2004039524

    申请日：2004-11-24

    Applicant: DELTANOID PHARMACEUTICALS INC ,  DELUCA HECTOR F ,  PLUM LORI A ,  KE HAU ZHE ,  BROWN THOMAS A

    Inventor： DELUCA HECTOR F ,  PLUM LORI A ,  KE HAU ZHE ,  BROWN THOMAS A

    IPC: A61K31/59 ,  A61K31/592 ,  A61K31/593 ,  A61P3/04

    CPC classification number: A61K31/59 ,  A61K31/592 ,  A61K31/593

    Abstract: A treatment for obesity and overweight comprises administering a vitamin D analog. The analog effectively inhibits an increase in body fat to animals at risk and decreases the basal fat content of animals. The treatment has a positive effect on the lean body component such that while there is an overall decrease in body weight, there is also a decrease in percent body fat. This decrease can be proportionally greater than the overall decrease in body weight. In addition, the treatment has a positive effect on bone turnover and osteogeneses making the vitamin D analog a beneficial treatment for the symptoms of menopause. Various exemplary embodiments of the treatment use the 2-alkylidene derivatives of vitamin D3, such as the 2-alkyliden-19-nor derivatives in both the R and S configurations at carbon-20.

    Abstract translation: 肥胖和超重的治疗包括施用维生素D类似物。 模拟物有效地抑制身体脂肪增加到有风险的动物，并降低动物的基础脂肪含量。 治疗对瘦体成分具有积极作用，使体重总体上下降，体脂百分比也降低。 这种减少可以成比例地大于体重的总体下降。 此外，治疗对骨转换和成骨细胞有积极影响，使维生素D类似物成为更年期症状的有益治疗。 处理的各种示例性实施方案使用维生素D3的2-亚烷基衍生物，例如在碳-20的R和S构型中的2-亚烷基-19-衍生物。

    METHODS FOR REDUCING BODY FAT USING VITAMIN D COMPOUNDS
    2.
    发明申请
    METHODS FOR REDUCING BODY FAT USING VITAMIN D COMPOUNDS 审中-公开
    使用维生素D化合物来降低人体脂肪的方法

    公开(公告)号：WO2005051396A2

    公开(公告)日：2005-06-09

    申请号：PCT/US2004/039524

    申请日：2004-11-24

    Applicant: DELTANOID PHARMACEUTICALS, INC. ,  DELUCA, Hector, F. ,  PLUM, Lori, A. ,  KE, Hau, Zhe ,  BROWN, Thomas, A.

    Inventor： DELUCA, Hector, F. ,  PLUM, Lori, A. ,  KE, Hau, Zhe ,  BROWN, Thomas, A.

    IPC: A61K31/539

    CPC classification number: A61K31/59 ,  A61K31/592 ,  A61K31/593

    Abstract: A treatment for obesity and overweight comprises administering a vitamin D analog. The analog effectively inhibits an increase in body fat to animals at risk and decreases the basal fat content of animals. The treatment has a positive effect on the lean body component such that while there is an overall decrease in body weight, there is also a decrease in percent body fat. This decrease can be proportionally greater than the overall decrease in body weight. In addition, the treatment has a positive effect on bone turnover and osteogeneses making the vitamin D analog a beneficial treatment for the symptoms of menopause. Various exemplary embodiments of the treatment use the 2-alkylidene derivatives of vitamin D 3 , such as the 2-alkyliden-19-nor derivatives in both the R and S configurations at carbon-20.

    Abstract translation: 治疗肥胖和超重包括施用维生素D类似物。 该类似物有效抑制危险动物体内脂肪的增加，并降低动物的基础脂肪含量。 该治疗对瘦体组分具有积极作用，从而尽管体重总体下降，但体脂百分比也降低。 这种下降可以按比例大于体重总体下降。 此外，该治疗对骨转换和骨生成具有积极作用，使维生素D类似物成为更年期症状的有益治疗。 治疗的各种示例性实施方案在碳-20的R和S构型中均使用维生素D 3的2-亚烷基衍生物，例如2-亚烷基-19-去甲衍生物。

    APPARATUS AND METHODS FOR SELECTIVE INTERFERENCE MITIGATION
    3.
    发明申请
    APPARATUS AND METHODS FOR SELECTIVE INTERFERENCE MITIGATION 审中-公开
    选择干扰减缓的装置和方法

    公开(公告)号：WO0173956A3

    公开(公告)日：2002-01-03

    申请号：PCT/US0109035

    申请日：2001-03-21

    Applicant: ERICSSON TELEFON AB L M ,  BROWN THOMAS A

    Inventor： BROWN THOMAS A

    IPC: H04B1/10

    CPC classification number: H04B1/1027

    Abstract: Selective compensation for interference in a communications system, such as a piconet or scatternet using an Industrial-Scientific-Medical (ISM) frequency band, may be achieved, according to embodiments of the present invention, by adapting the interference mitigation scheme applied in a communications system based on comparison with known patterns associated with particular types of interference, such as interference generated by microwave ovens, medical equipment, industrial equipment and wireless communications devices. According to embodiments of the present invention, a communications system, such as wireless communications system, detects interference and changes from a first interference mitigation scheme to a second interference mitigation scheme if the detected interference exhibits a pattern sufficiently correlated with predetermined pattern associated with a predetermined type of interference, such as the half-cycle pulsed pattern typical of a microwave oven.

    Abstract translation: 根据本发明的实施例，通过适应通信中应用的干扰减轻方案，可以实现使用工业科学 - 医学（ISM）频带的诸如微微网或分散网络之类的通信系统中的干扰的选择性补偿 基于与特定类型的干扰相关联的已知模式的比较，例如由微波炉，医疗设备，工业设备和无线通信设备产生的干扰。 根据本发明的实施例，诸如无线通信系统的通信系统如果检测到的干扰表现出与预定的相关联的预定模式充分相关的模式，则将干扰和从第一干扰减轻方案的改变检测到第二干扰减轻方案 干扰类型，如微波炉典型的半周期脉冲模式。

    CAM STYLE LOCKS AND SYSTEMS AND METHODS INCLUDING THE SAME
    4.
    发明申请
    CAM STYLE LOCKS AND SYSTEMS AND METHODS INCLUDING THE SAME 审中-公开
    CAM风格的锁定和系统以及包括其中的方法

    公开(公告)号：WO2013062641A1

    公开(公告)日：2013-05-02

    申请号：PCT/US2012/045595

    申请日：2012-07-05

    Applicant: DIRTT ENVIRONMENTAL SOLUTIONS INC. ,  GOSLING, Geoff ,  SMED, Mogens, F. ,  BROWN, Thomas, A.

    Inventor： GOSLING, Geoff ,  SMED, Mogens, F. ,  BROWN, Thomas, A.

    IPC: E05B15/00 ,  E05B15/10

    CPC classification number: E05C3/12 ,  E05B15/00 ,  E05B15/10 ,  E05B63/00 ,  E05B63/0013 ,  E05C3/00 ,  E05C3/045 ,  F16H25/14 ,  Y10T74/2101 ,  Y10T292/1077

    Abstract: The present invention includes door locks having a cam having three lobes, and to systems including such door locks. The outer lobes of the cam can limit the rotation of the cam. By limiting the rotation of the cam, the outer lobes can ensure that the cam is always ready for immediate activation. The outer lobes can also strike against outer pins of a locking mechanism to cause the cam to rotate with the locking mechanism when the locking mechanism is activated from the opposite side of the locking mechanism. The present invention also extends to methods of installing and using a door lock including three lobes.

    Abstract translation: 本发明包括具有三个凸角的凸轮的门锁和包括这种门锁的系统。 凸轮的外凸角可以限制凸轮的旋转。 通过限制凸轮的旋转，外凸角可以确保凸轮始终准备好立即激活。 当锁定机构从锁定机构的相对侧被致动时，外部凸角也可以抵靠锁定机构的外部销，使其与锁定机构一起转动。 本发明还涉及安装和使用包括三个叶片的门锁的方法。

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