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    ATTACHMENT OF MATERIAL TO AN IMPLANTABLE FRAME BY CROSS-LINKING
    3.
    发明申请
    ATTACHMENT OF MATERIAL TO AN IMPLANTABLE FRAME BY CROSS-LINKING 审中-公开
    通过交叉连接材料到可植入的框架

    公开(公告)号：WO2007028052B1

    公开(公告)日：2008-01-24

    申请号：PCT/US2006034276

    申请日：2006-09-01

    Applicant: COOK INC ,  RAM PAUL H ,  CASE BRIAN C ,  HOFFMAN GRANT T

    Inventor： RAM PAUL H ,  CASE BRIAN C ,  HOFFMAN GRANT T

    IPC: A61L27/36 ,  A61L27/50

    CPC classification number: A61L27/3633 ,  A61F2/2418 ,  A61F2/2475 ,  A61F2220/0016 ,  A61F2220/0058 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61L27/3629 ,  A61L27/50

    Abstract: Medical devices for implantation in a body vessel, and methods of using and making the same, are provided. A medical device includes a frame and a cross-linkable material having at least one cross-linked region and a non cross-linked region, where the cross-linked region maintains the cross-linkable material in connection to the frame. A method of making an implantable medical device includes providing a frame and covering the frame with a cross-linkable material. The method also includes cross-linking at least one region of the cross-linkable material by joining a first region of the cross-linkable material to a second region of the cross- linkable material to form a point of attachment. A method of treating a subject includes the step of implanting the medical device at a point of treatment.

    Abstract translation: 提供了用于植入体内的医疗装置及其使用和制造方法。 医疗装置包括具有至少一个交联区域和非交联区域的框架和可交联材料，其中交联区域将可交联材料保持在与框架连接的位置。 制造可植入医疗装置的方法包括提供框架并用可交联材料覆盖框架。 该方法还包括通过将可交联材料的第一区域连接到可交联材料的第二区域以形成连接点来交联可交联材料的至少一个区域。 治疗对象的方法包括在治疗点植入医疗装置的步骤。

    SELF-ORIENTING DELIVERY SYSTEM
    5.
    发明申请
    SELF-ORIENTING DELIVERY SYSTEM 审中-公开
    自我定向交付系统

    公开(公告)号：WO2007130614A2

    公开(公告)日：2007-11-15

    申请号：PCT/US2007/010902

    申请日：2007-05-04

    Applicant: COOK INCORPORATED ,  CASE, Brian, C. ,  PAUL, Ram, H., Jr.

    Inventor： CASE, Brian, C. ,  PAUL, Ram, H., Jr.

    CPC classification number: A61M25/01 ,  A61F2/95 ,  A61F2002/30125 ,  A61F2002/30538 ,  A61F2230/0008 ,  A61F2250/0006 ,  A61M25/0074 ,  A61M25/0082

    Abstract: Delivery systems for delivering and deploying expandable intraluminal medical devices within a body vessel are provided. A portion of the delivery system that includes the expandable intraluminal medical device orients itself about an axis based on characteristics of the body vessel, such as the relative orientation of major and minor axes of the vessel. This allows the intraluminal medical device to be deployed in the vessel in a desired orientation relative to the vessel. Embodiments can be used with any suitable intraluminal medical device, including valve devices, stents, drug-coated stents, filters, and other suitable devices. Methods of delivering and deploying intraluminal medical devices are also described.

    Abstract translation: 提供了用于在身体容器内递送和部署可膨胀的管腔内医疗装置的输送系统。 包括可扩张管腔内医疗装置的输送系统的一部分基于身体血管的特征（例如血管的主轴和短轴的相对取向）绕轴线定向。 这允许管腔内医疗装置相对于容器以期望的方向部署在容器中。 实施例可以与任何合适的管腔内医疗装置一起使用，包括瓣膜装置，支架，药物涂层的支架，过滤器和其它合适的装置。 还描述了递送和部署管腔内医疗装置的方法。

    PROTHESIS ADAPTED FOR PLACEMENT UNDER EXTERNAL IMAGING
    9.
    发明申请
    PROTHESIS ADAPTED FOR PLACEMENT UNDER EXTERNAL IMAGING 审中-公开
    适用于外部成像放置的标准

    公开(公告)号：WO2004075789A2

    公开(公告)日：2004-09-10

    申请号：PCT/US2004005750

    申请日：2004-02-26

    Applicant: COOK INC ,  CASE BRIAN C ,  FLAGLE JACOB A ,  GARRISON MICHAEL L ,  HOFFA ANDREW K ,  LEONARD RAY II

    Inventor： CASE BRIAN C ,  FLAGLE JACOB A ,  GARRISON MICHAEL L ,  HOFFA ANDREW K ,  LEONARD RAY II

    IPC: A61B19/00 ,  A61F2/00 ,  A61F2/06 ,  A61F2/24 ,  A61F2/02

    CPC classification number: A61F2/2475 ,  A61B90/39 ,  A61F2/2418 ,  A61F2230/0026 ,  A61F2230/0095 ,  A61F2250/0098

    Abstract: A expandable prosthesis having an imageable structure comprising one or more elements visually distinguishable by an external (e.g., radiographic or ultrasonic) imaging system, the structure being located about a first axis that corresponds to a structural feature of the prosthesis that is configured to perform a specific function particular to that axis. The imageable structure is configured to assist in the rotational orientation of the prosthesis during placement within the implantation site. In one embodiment the prosthesis comprises a venous valve that includes imageable elements or structure, such as a pair of radiopaque markers, that defines the orifice of the valve structure such that the orifice can be oriented with a particular anatomical feature under imaging, such as to align the orifice with the long axis of the vessel. In another embodiment, the imageable structure is configured to permit an aperture located about a stent graft to be oriented with a anatomical feature of the vessel, such as a branch vessel opening. The invention includes a method for using imageable structure to confirm that the orientation of the prosthesis within a delivery apparatus is consistent the desired delivery approach to be used.

    Abstract translation: 一种具有可成像结构的可扩张假体，其包括可由外部（例如，射线照相或超声）成像系统在视觉上区分的一个或多个元件，所述结构围绕与假体的结构特征对应的第一轴定位，所述第一轴被配置为执行 特定于该轴的特定功能。 可成像结构构造成在放置在植入部位期间有助于假体的旋转取向。 在一个实施例中，假体包括静脉瓣，其包括可成像元件或结构，例如一对不透射线的标记，其限定瓣结构的孔，使得孔可以在成像下具有特定的解剖特征，诸如 将孔与容器的长轴对齐。 在另一个实施例中，可成像结构被配置为允许围绕支架移植物定位的孔与容器的解剖特征（例如分支血管开口）定向。 本发明包括一种使用可成像结构来确认假体在输送装置内的取向与所要使用的输送方法一致的方法。

    MEDICAL DEVICE DELIVERY SYSTEM WITH SHEATH SEPARATION
    10.
    发明申请
    MEDICAL DEVICE DELIVERY SYSTEM WITH SHEATH SEPARATION 审中-公开
    医疗器械输送系统与分离

    公开(公告)号：WO2008121380A1

    公开(公告)日：2008-10-09

    申请号：PCT/US2008/004157

    申请日：2008-03-31

    Applicant: COOK INCORPORATED ,  HOFFMAN, Grant, T. ,  CASE, Brian, C.

    Inventor： HOFFMAN, Grant, T. ,  CASE, Brian, C.

    IPC: A61F2/84

    CPC classification number: A61F2/95 ,  A61F2/958 ,  A61F2/97

    Abstract: Medical device delivery systems and associated methods are provided. Delivery systems according to the invention include an elongated tubular member and a body member, such as a dilator, disposed therein. An intraluminal medical device is disposed on the dilator and within the tubular member prior to deployment. The delivery system includes a means for separating two or more portions of the distal end of the tubular member that aids in deploying the intraluminal medical device from the delivery system by separating two or more portions of the tubular member from each other to facilitate release of the intraluminal medical device from the body member. Various structures can be used for means for separating, including a cutting ring, activateable material on the tubular member, or other suitable structure. The provided devices and methods reduce friction occuring from relative movement between the sheath and dilator during deployment.

    Abstract translation: 提供医疗器械输送系统及相关方法。 根据本发明的递送系统包括细长管状构件和布置在其中的诸如扩张器的主体构件。 在展开之前，将管腔内医疗装置设置在扩张器上并在管状构件内。 递送系统包括用于分离管状构件的远端的两个或更多个部分的装置，其通过将管状构件的两个或更多个部分彼此分离来有助于将管腔内医疗装置从输送系统展开以便于释放 管腔内医疗器械从身体成员。 各种结构可以用于分离的装置，包括切割环，管状构件上的可激活材料或其他合适的结构。 所提供的装置和方法减少在展开期间由护套和扩张器之间的相对运动发生的摩擦力。

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