公开(公告)号：WO2012051287A1

公开(公告)日：2012-04-19

申请号：PCT/US2011/055950

申请日：2011-10-12

Applicant: KRAFT FOODS GLOBAL BRANDS LLC ,  CHU, Yi-Fang ,  CHEN, Yumin ,  BROWN, Peter H. ,  LYLE, Barbara J.

Inventor： CHU, Yi-Fang ,  CHEN, Yumin ,  BROWN, Peter H. ,  LYLE, Barbara J.

IPC: A23L1/30 ,  A61K8/97 ,  A61K31/35 ,  A61K36/74

CPC classification number: A61K31/05 ,  A23L33/105 ,  A23V2002/00 ,  A61K8/347 ,  A61K8/4953 ,  A61K8/97 ,  A61K31/35 ,  A61K31/522 ,  A61K45/06 ,  A61K2800/10 ,  A61Q19/00 ,  A61K2300/00 ,  A23V2200/302 ,  A23V2200/322 ,  A23V2200/324 ,  A23V2200/328 ,  A23V2250/2108 ,  A23V2250/2132

Abstract: Embodiments are related to compositions of matter comprising a food, drug, cosmetic, dietary supplement, or biologic product, said product comprised of a phytochemical fraction recovered from a crude caffeine, said phytochemical fraction having a ratio of polyphenols to caffeine of about 20, 10-30 or 40, or greater than 10. In related embodiments, said phytochemical fraction is a retentate of a filtration process of a water suspension of crude caffeine, and wherein said crude caffeine is a product of a green coffee bean decaffeination process. In other related embodiments, said compositions of matter are useful for facilitating neuroprotection, inhibiting COX-2, or stimulating glucose uptake.

Abstract translation: 实施方案涉及包含食品，药物，化妆品，膳食补充剂或生物制品的物质的组合物，所述产物由从粗咖啡因回收的植物化学级分组成，所述植物化学级分的多酚与咖啡因的比例为约20,10 -30或40，或大于10.在相关实施方案中，所述植物化学级分是粗咖啡因的水悬浮液的过滤方法的滞留物，并且其中所述粗咖啡因是生咖啡豆脱咖啡因方法的产物。 在其它相关实施方案中，所述物质组合物可用于促进神经保护作用，抑制COX-2或刺激葡萄糖摄取。