公开(公告)号：WO2012036836A4

公开(公告)日：2012-03-22

申请号：PCT/US2011/048202

申请日：2011-08-18

Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S. A. ,  CHILDERS, Robert, W. ,  LO, Ying-Cheng ,  HOPPING, Peter

Inventor： CHILDERS, Robert, W. ,  LO, Ying-Cheng ,  HOPPING, Peter

IPC: A61M1/28

Abstract: The present system and method in one embodiment limit a maximum instantaneous peritoneal volume to a comfortable level, while allowing the dialysis machine to advance to fill a prescribed volume whenever the drain ends after a minimum drain percentage has been attained. If a low drain condition occurs, the nominal fill volume is lowered and a therapy cycle is added, so that a prescribed total amount of fresh therapy fluid is used during therapy, maximizing therapeutic benefit. An allowable residual volume at the end of an incomplete drain is increased, thereby lowering the probability of a subsequent low drain condition.

公开(公告)号：WO2010006146A3

公开(公告)日：2010-06-17

申请号：PCT/US2009050073

申请日：2009-07-09

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA ,  CHILDERS ROBERT W ,  YU ANPING ,  CIZMAN BORUT

Inventor： CHILDERS ROBERT W ,  YU ANPING ,  CIZMAN BORUT

IPC: A61M1/28 ,  G06F19/00

CPC classification number: A61M1/287 ,  A61M1/28 ,  A61M1/282 ,  A61M2205/12 ,  A61M2205/3553 ,  A61M2205/3584 ,  A61M2205/52 ,  G06F19/327 ,  G06F19/3437 ,  G06F19/3456 ,  G06F19/3481 ,  G06F19/3487 ,  G06Q10/087 ,  G16H15/00 ,  G16H40/20 ,  G16H50/50

Abstract: A peritoneal dialysis system includes: a plurality of automated peritoneal dialysis ("APD") machines (102); and a server computer (118) in communication with the APD machines, the APD machines programmed to inform the server computer of how much dialysate is consumed over a first delivery period, the server computer configured to use the amounts consumed to determine dialysate delivery amounts for the plurality of APD machines for a second delivery period.

Abstract translation: 腹膜透析系统包括：多个自动腹膜透析（“APD”）机器（102）; 以及与APD机器通信的服务器计算机（118），所述APD机器被编程为通知服务器计算机在第一传送期间消耗多少透析液，所述服务器计算机被配置为使用消耗的量来确定透析液传送量 所述多个APD机器用于第二传送周期。

公开(公告)号：WO2010006131A4

公开(公告)日：2010-04-22

申请号：PCT/US2009050056

申请日：2009-07-09

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA ,  YU ANPING ,  CHILDERS ROBERT W ,  VONESH EDWARD F ,  CIZMAN BORUT

Inventor： YU ANPING ,  CHILDERS ROBERT W ,  VONESH EDWARD F ,  CIZMAN BORUT

IPC: A61M1/28 ,  G06F19/00

CPC classification number: A61M1/28 ,  A61M1/281 ,  A61M1/282 ,  A61M1/287 ,  A61M2205/502 ,  G06F19/3418 ,  G06F19/3481 ,  G16H10/60 ,  G16H50/50 ,  Y10S706/924

Abstract: A peritoneal dialysis system includes a logic implementer configured to: (i) accept at least one therapy target input; (ii) accept at least one patient transport characteristic input; (iii) accept at least one solution input; (iv) accept at least one fluid volume input; (v) accept at least one therapy time input, at least one of the inputs (ii) to (v) including an input range; and (vi) generate each therapy regimen using the inputs of (ii), (iii), (iv) and (v), including each of the possibilities within the at least one input range, that satisfy the at least one therapy target input.

Abstract translation: 腹膜透析系统包括逻辑实现器，其被配置成：（i）接受至少一个治疗目标输入; （ii）接受至少一个患者运输特征输入; （iii）接受至少一个解决方案输入; （iv）接受至少一个流体体积输入; （v）接受至少一个治疗时间输入，输入（ii）至（v）中的至少一个包括输入范围; 以及（vi）使用（ii），（iii），（iv）和（v）的输入生成每个治疗方案，所述输入包括所述至少一个输入范围内的每个可能性，以满足所述至少一个治疗目标输入 。

公开(公告)号：WO2010006131A3

公开(公告)日：2010-03-04

申请号：PCT/US2009050056

申请日：2009-07-09

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA ,  YU ANPING ,  CHILDERS ROBERT W ,  VONESH EDWARD F ,  CIZMAN BORUT

Inventor： YU ANPING ,  CHILDERS ROBERT W ,  VONESH EDWARD F ,  CIZMAN BORUT

IPC: A61M1/28 ,  G06F19/00

CPC classification number: A61M1/28 ,  A61M1/281 ,  A61M1/282 ,  A61M1/287 ,  A61M2205/502 ,  G06F19/3418 ,  G06F19/3481 ,  G16H10/60 ,  G16H50/50 ,  Y10S706/924

Abstract: A peritoneal dialysis system includes a logic implementer configured to: (i) accept at least one therapy target input; (ii) accept at least one patient transport characteristic input; (iii) accept at least one solution input; (iv) accept at least one fluid volume input; (v) accept at least one therapy time input, at least one of the inputs (ii) to (v) including an input range; and (vi) generate each therapy regimen using the inputs of (ii), (iii), (iv) and (v), including each of the possibilities within the at least one input range, that satisfy the at least one therapy target input.

公开(公告)号：WO2010006137A1

公开(公告)日：2010-01-14

申请号：PCT/US2009/050062

申请日：2009-07-09

Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A. ,  YU, Anping ,  CHILDERS, Robert, W. ,  CIZMAN, Borut

Inventor： YU, Anping ,  CHILDERS, Robert, W. ,  CIZMAN, Borut

IPC: A61M1/28 ,  G06F19/00

CPC classification number: G06F19/3456 ,  A61M1/1601 ,  A61M1/28 ,  A61M1/281 ,  A61M1/282 ,  A61M1/287 ,  A61M2205/3553 ,  A61M2205/3584 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2209/01 ,  B01D61/32 ,  G06F19/00 ,  G06F19/3418

Abstract: In one embodiment an automated peritoneal dialysis ("APD") machine (104) includes: at least one pump; a logic implementer storing a plurality of therapy prescriptions by which to operate the at least one pump, each therapy prescription pre-approved for a particular patient; and an input device (160) operating with the logic implementer to allow the patient to select one of the therapy prescriptions for a particular therapy. In another embodiment, the input device operating with the logic implementer allows a doctor/clinician to select or approve one of the therapy prescriptions to be run on the APD machine. In a further embodiment, the logic implementer is programmed to select or suggest one of the therapy prescriptions to be run on the is APD machine.

Abstract translation: 在一个实施例中，自动腹膜透析（“APD”）机器（104）包括：至少一个泵; 存储多个用于操作所述至少一个泵的治疗处方的逻辑实现器，为特定患者预先批准的每个治疗处方; 以及与逻辑实现者一起操作的输入设备（160），以允许患者选择用于特定治疗的治疗处方之一。 在另一个实施例中，与逻辑实施器一起操作的输入设备允许医生/临床医生选择或批准在APD机器上运行的治疗处方之一。 在另一实施例中，逻辑实现器被编程为选择或建议要在APD机器上运行的治疗处方之一。

公开(公告)号：WO2008100670A1

公开(公告)日：2008-08-21

申请号：PCT/US2008/051260

申请日：2008-01-17

Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A. ,  ROGER, Rodolfo G. ,  TEJEDOR, Joel ,  CHILDERS, Robert W.

Inventor： ROGER, Rodolfo G. ,  TEJEDOR, Joel ,  CHILDERS, Robert W.

IPC: A61M1/36

CPC classification number: A61M1/30 ,  A61M1/3653 ,  A61M1/3656 ,  A61M1/3661 ,  A61M2205/13 ,  A61M2205/15 ,  A61M2205/17 ,  A61M2205/3313 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/8206 ,  A61M2230/65

Abstract: An access disconnection system (80) includes: a material (82) capable of absorbing blood from a patient upon an arterial or venous line disconnection; a light emitter (92) positioned to emit light onto the material; a light receiver (92) positioned to receive light reflected off of the material; and electronic circuitry (90) operably coupled to at least one of the light emitter and receiver, the circuitry configured to provide an output (i) when light received by the receiver reaches a particular level or (ii) indicative of an amount of light received by the light receiver.

Abstract translation: 进入断开系统（80）包括：能够在动脉或静脉线路断开时从患者吸收血液的材料（82）; 定位成将光发射到所述材料上的光发射器（92） 定位成接收从材料反射的光的光接收器（92） 以及可操作地耦合到所述光发射器和接收器中的至少一个的电子电路（90），所述电路被配置为当由所述接收器接收的光达到特定水平时提供输出（i），或（ii）指示所接收的光的量 由光接收器。

公开(公告)号：WO2010006140A4

公开(公告)日：2010-08-26

申请号：PCT/US2009050066

申请日：2009-07-09

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA ,  YU ANPING ,  GRAYSON JAMES ,  CHILDERS ROBERT W

Inventor： YU ANPING ,  GRAYSON JAMES ,  CHILDERS ROBERT W

IPC: A61M1/28 ,  G06F19/00

CPC classification number: A61M1/282 ,  A61M1/28 ,  A61M1/281 ,  A61M1/287 ,  A61M2205/18 ,  A61M2205/3303 ,  A61M2205/3327 ,  A61M2205/3553 ,  A61M2205/3592 ,  A61M2205/502 ,  A61M2230/005 ,  A61M2230/30

Abstract: A peritoneal dialysis system includes: an automated peritoneal dialysis ("APD") machine (102a) configured to remove ultraf iltrate ("UF") from a patient and record how much UF has been removed; and a logic implementer configured to (i) form a first moving average UF removed trend, (ii) determine a trending range around the first moving average UF removed trend, (iii) determine at least one of an upper and lower UF removed limit from the trending range, (iv) form a second moving average UF removed trend, and (v) alert if the second moving average UF removed trend moves outside of the at least one UF removed limit.

Abstract translation: 腹膜透析系统包括：自动腹膜透析（“APD”）机器（102a），被配置为从患者移除超滤（“UF”）并记录已经去除了多少UF; 以及逻辑实现器，被配置为（i）形成第一移动平均UF去除趋势，（ii）确定围绕所述第一移动平均UF移除趋势的趋势范围，（iii）确定从UF移除的上限和下限移除限制中的至少一个 趋势范围，（iv）形成第二移动平均UF去除趋势，以及（v）如果第二移动平均UF移除趋势移动到至少一个UF移除限制之外，则警告。

公开(公告)号：WO2010006140A3

公开(公告)日：2010-06-17

申请号：PCT/US2009050066

申请日：2009-07-09

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA ,  YU ANPING ,  GRAYSON JAMES ,  CHILDERS ROBERT W

Inventor： YU ANPING ,  GRAYSON JAMES ,  CHILDERS ROBERT W

IPC: A61M1/28 ,  G06F19/00

CPC classification number: A61M1/282 ,  A61M1/28 ,  A61M1/281 ,  A61M1/287 ,  A61M2205/18 ,  A61M2205/3303 ,  A61M2205/3327 ,  A61M2205/3553 ,  A61M2205/3592 ,  A61M2205/502 ,  A61M2230/005 ,  A61M2230/30

Abstract: A peritoneal dialysis system includes: an automated peritoneal dialysis ("APD") machine (102a) configured to remove ultraf iltrate ("UF") from a patient and record how much UF has been removed; and a logic implementer configured to (i) form a first moving average UF removed trend, (ii) determine a trending range around the first moving average UF removed trend, (iii) determine at least one of an upper and lower UF removed limit from the trending range, (iv) form a second moving average UF removed trend, and (v) alert if the second moving average UF removed trend moves outside of the at least one UF removed limit.

Abstract translation: 腹膜透析系统包括：自动腹膜透析（“APD”）机器（102a），其被配置为从患者移除超滤液（“UF”）并记录已移除了多少UF; 以及逻辑实现器，其被配置为（i）形成第一移动平均UF移除趋势，（ii）确定围绕所述第一移动平均UF移除趋势的趋势范围，（iii）确定从UF移除的上限和下限中的至少一个 趋势范围，（iv）形成第二移动平均UF移除趋势，以及（v）如果第二移动平均UF移除趋势移动超出至少一个UF移除限制，则发出警报。

公开(公告)号：WO2010006147A1

公开(公告)日：2010-01-14

申请号：PCT/US2009/050074

申请日：2009-07-09

Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A. ,  YU, Anping ,  VONESH, Edward, F. ,  KELLAM, Benjamin ,  CHILDERS, Robert, W. ,  CIZMAN, Borut

Inventor： YU, Anping ,  VONESH, Edward, F. ,  KELLAM, Benjamin ,  CHILDERS, Robert, W. ,  CIZMAN, Borut

IPC: A61M1/28 ,  G06F19/00

CPC classification number: G06F19/3481 ,  A61M1/28 ,  A61M1/282 ,  A61M1/287 ,  A61M2205/12 ,  A61M2205/3553 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/52 ,  G06F19/00 ,  G16H15/00 ,  G16H40/20 ,  G16H50/50

Abstract: An ultrafiltration ("UF") evaluation method includes: (i) determining an amount of UF removed from a patient over a first dwell time; (ii) determine an amount of UF removed from the patient over a second, different dwell time; (iii) determining an amount of UF removed from the patient over a third, different dwell time; and (iv) fitting a curve to the UF removal amounts for the first, second and third dwell time. A peritoneal dialysis therapy generation method using the curve determined according to the "UF" evaluation method to generate at least one peritoneal dialysis therapy regimen.

Abstract translation: 超滤（“UF”）评估方法包括：（i）确定在第一停留时间内从患者移除的UF的量; （ii）确定在第二个不同的停留时间内从患者移除的UF的量; （iii）确定在三分之一不同的停留时间内从患者移除的UF的量; 和（iv）将曲线拟合到第一，第二和第三停留时间的UF去除量。 使用根据“UF”评估方法确定的曲线产生至少一个腹膜透析治疗方案的腹膜透析治疗产生方法。

公开(公告)号：WO2010006131A2

公开(公告)日：2010-01-14

申请号：PCT/US2009/050056

申请日：2009-07-09

Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A. ,  YU, Anping ,  CHILDERS, Robert W. ,  VONESH, Edward F. ,  CIZMAN, Borut

Inventor： YU, Anping ,  CHILDERS, Robert W. ,  VONESH, Edward F. ,  CIZMAN, Borut

IPC: A61M1/28 ,  G06F19/00

CPC classification number: A61M1/28 ,  A61M1/281 ,  A61M1/282 ,  A61M1/287 ,  A61M2205/502 ,  G06F19/00 ,  G06F19/3418 ,  G06F19/3481 ,  G16H10/60 ,  G16H50/50 ,  Y10S706/924

Abstract: A peritoneal dialysis system includes a logic implementer configured to: (i) accept at least one therapy target input; (ii) accept at least one patient transport characteristic input; (iii) accept at least one solution input; (iv) accept at least one fluid volume input; (v) accept at least one therapy time input, at least one of the inputs (ii) to (v) including an input range; and (vi) generate each therapy regimen using the inputs of (ii), (iii), (iv) and (v), including each of the possibilities within the at least one input range, that satisfy the at least one therapy target input.

Abstract translation: 腹膜透析系统包括逻辑实现器，其被配置为：（i）接受至少一个治疗目标输入; （ii）接受至少一个患者运输特征输入; （iii）接受至少一个解决方案输入; （iv）接受至少一个流体体积输入; （v）接受至少一个治疗时间输入，所述输入（ii）至（v）中的至少一个包括输入范围; 和（vi）使用（ii），（iii），（iv）和（v）的输入产生每种治疗方案，包括满足至少一种治疗目标输入的至少一个输入范围内的每种可能性 。