公开(公告)号：WO2013043449A1

公开(公告)日：2013-03-28

申请号：PCT/US2012/055053

申请日：2012-09-13

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  CHRISTENSEN, Leif

Inventor： CHRISTENSEN, Leif

IPC: H01M4/13 ,  H01M4/505 ,  H01M4/525 ,  H01M4/38 ,  H01M10/0525

CPC classification number: H01M4/04 ,  H01M4/366 ,  H01M4/382 ,  H01M4/386 ,  H01M4/387 ,  H01M4/505 ,  H01M4/525 ,  H01M10/0525 ,  H01M2004/028 ,  Y10T29/49108

Abstract: High capacity lithium-ion electrochemical cells and methods of making the same are provided that include a positive electrode that includes a lithium mixed metal oxide having a first irreversible capacity and a negative electrode that includes an alloy anode material having a first irreversible capacity when the anode is delithiated to 0.9 V vs. Li/Li + . The lithium mixed metal oxide includes at least one of nickel, cobalt, and manganese. The alloy anode compound includes at least one of silicon and tin. The first cycle irreversible capacity of the positive electrode is greater than or equal to the first cycle irreversible capacity loss of the negative electrode.

Abstract translation: 提供了高容量锂离子电化学电池及其制造方法，其包括正极，其包括具有第一不可逆容量的锂复合金属氧化物和负极，其包含当阳极为第一不可逆容量的合金阳极材料 相对于Li / Li +释放到0.9V。 锂复合金属氧化物包括镍，钴和锰中的至少一种。 合金阳极化合物包括硅和锡中的至少一种。 正极的第一循环不可逆容量大于或等于负极的第一循环不可逆容量损失。

公开(公告)号：WO2012112316A1

公开(公告)日：2012-08-23

申请号：PCT/US2012/023750

申请日：2012-02-03

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  CHRISTENSEN, Leif

Inventor： CHRISTENSEN, Leif

IPC: H01M4/04 ,  H01M10/0525 ,  H01M4/485 ,  H01M4/505 ,  H01M4/525 ,  H01M4/1391

CPC classification number: H01M4/52 ,  C01G53/50 ,  C01P2004/03 ,  C01P2004/84 ,  C01P2006/40 ,  H01M4/0471 ,  H01M4/1391 ,  H01M4/366 ,  H01M4/485 ,  H01M4/505 ,  H01M4/525 ,  H01M10/0525 ,  H01M2004/028

Abstract: Composite particles include a core comprising a layered lithium metal oxide having an O3 crystal structure. A shell layer having an O3 crystal structure encloses the core. The shell layer includes an oxygen-loss, layered lithium metal oxide. The core comprises from 30 to 85 mole percent of the composite particles. A cathode and a lithium-ion battery including the composite particles, and methods of making the foregoing are also disclosed.

Abstract translation: 复合颗粒包括包含具有O 3晶体结构的层状锂金属氧化物的芯。 具有O 3晶体结构的壳层包围芯。 壳层包括氧损失层状锂金属氧化物。 核心包含30至85摩尔％的复合颗粒。 还公开了包括复合颗粒的阴极和锂离子电池及其制备方法。

公开(公告)号：WO2010069312A1

公开(公告)日：2010-06-24

申请号：PCT/DK2008/050311

申请日：2008-12-16

Applicant: WIDEX A/S ,  YU, Yihua ,  CHRISTENSEN, Leif Hojslet ,  VESTERGAARD, Jorn Eiler ,  OLSEN, Jorgen Mejner ,  LARSEN, Tina Ahlberg

Inventor： YU, Yihua ,  CHRISTENSEN, Leif Hojslet ,  VESTERGAARD, Jorn Eiler ,  OLSEN, Jorgen Mejner ,  LARSEN, Tina Ahlberg

IPC: H04R25/00 ,  C09D5/00 ,  C09D7/12 ,  C09D133/18

CPC classification number: H04R25/658 ,  C08K3/04 ,  C08K9/04 ,  C09D7/70 ,  C09D133/20 ,  C09D135/06 ,  H04R25/65 ,  H04R25/654

Abstract: A method for coating a hearing aid component, which comprises providing a hearing aid component; providing organic nanoparticles, such as polymeric particles or carbon nanotubes; optionally functionalisingthe organic nanoparticles with perfluoro moieties; suspending the optionally functionalised nanoparticles in a volatile solvent; applying the suspension of the optionally functionalised nanoparticles to the hearing aid component; and evaporating the volatile solvent to form a coating. The invention also relates to a coating for a hearing aid component produced in the method of the invention, and a hearing aid component provided with the coating. The invention also relates to a hearing aid comprising the component.

Abstract translation: 一种用于涂覆助听器组件的方法，其包括提供助听器组件; 提供有机纳米颗粒，例如聚合物颗粒或碳纳米管; 任选地用全氟部分官能化有机纳米颗粒; 将任选的官能化纳米颗粒悬浮在挥发性溶剂中; 将任选官能化的纳米颗粒的悬浮液施加到助听器组件; 并蒸发挥发性溶剂以形成涂层。 本发明还涉及在本发明的方法中制备的助听器组件的涂层和设置有涂层的助听器组件。 本发明还涉及包括该组件的助听器。

公开(公告)号：WO2009004057A3

公开(公告)日：2009-01-08

申请号：PCT/EP2008/058589

申请日：2008-07-03

Applicant: NOVO NORDISK A/S ,  LINGYUN, Wang ,  JINCHAO, Zhang ,  CHRISTENSEN, Leif

Inventor： LINGYUN, Wang ,  JINCHAO, Zhang ,  CHRISTENSEN, Leif

IPC: A61K38/22 ,  A61K47/22 ,  A61P35/00 ,  A61K38/27

Abstract: The patent application relates to antagonistic dimers of prolactin molecules and their use in treating cancer.

公开(公告)号：WO2008055972A3

公开(公告)日：2008-08-14

申请号：PCT/EP2007062127

申请日：2007-11-09

Applicant: NOVO NORDISK AS ,  PESCHKE BERND ,  CHRISTENSEN LEIF ,  PERSSON EGON

Inventor： PESCHKE BERND ,  CHRISTENSEN LEIF ,  PERSSON EGON

IPC: A61K47/48 ,  C07K14/575

CPC classification number: C07K14/57554 ,  A61K47/60

Abstract: The invention is concerned with N-terminally pegylated polypeptides capable of binding to the prolactin receptor. Such polypeptides may for instance be N-terminally pegylated antagonists of the prolactin receptor, such as for instance prolactin variants.

Abstract translation: 本发明涉及能结合催乳素受体的N-末端聚乙二醇化多肽。 这样的多肽可以例如是催乳素受体的N-末端聚乙二醇化拮抗剂，例如催乳素变体。

公开(公告)号：WO2008025355A1

公开(公告)日：2008-03-06

申请号：PCT/DK2006/000470

申请日：2006-08-31

Applicant: WIDEX A/S ,  VESTERGAARD, Jom Eiler ,  OLSEN, Jorgen Mejner ,  CHRISTENSEN, Leif Hojslet ,  HAUGSHOJ, Kenneth B.

Inventor： VESTERGAARD, Jom Eiler ,  OLSEN, Jorgen Mejner ,  CHRISTENSEN, Leif Hojslet ,  HAUGSHOJ, Kenneth B.

IPC: H04R25/00

CPC classification number: H04R25/654

Abstract: A hearing aid (1) comprises a receiver (19), an output port (6), a conduit (13) for conveying sound to the port and a barrier element (39) adapted for baffling entry of ear wax and moisture and for being acoustically transparent. The invention further provides a barrier element (39) for a hearing aid comprising a slab having an exterior surface and through openings for transverse transmission of sound, wherein the exterior surface is super-hydrophobic.

Abstract translation: 助听器（1）包括接收器（19），输出端口（6），用于将声音传送到端口的导管（13）和适于阻挡耳塞和水分进入的屏障元件（39） 声学透明。 本发明还提供了一种用于助听器的屏障元件（39），其包括具有外表面的平板和通过用于横向传播声音的开口，其中所述外表面是超疏水的。

公开(公告)号：WO2007009894A2

公开(公告)日：2007-01-25

申请号：PCT/EP2006/064027

申请日：2006-07-07

Applicant: NOVO NORDISK A/S ,  SENSFUSS, Ulrich ,  CHRISTENSEN, Leif ,  SPETZLER, Jane ,  FRIEBOES, Kilian Waldemar Conde ,  THØGERSEN, Henning

Inventor： SENSFUSS, Ulrich ,  CHRISTENSEN, Leif ,  SPETZLER, Jane ,  FRIEBOES, Kilian Waldemar Conde ,  THØGERSEN, Henning

IPC: A61K47/48 ,  C07K7/06 ,  C07K7/08

CPC classification number: C07K14/685 ,  A61K47/542 ,  A61K47/545

Abstract: The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.

Abstract translation: 本发明涉及有效调节一种或多种黑皮质素受体类型的新型肽化合物，治疗中化合物的用途，包括向有需要的患者施用化合物的治疗方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。

公开(公告)号：WO1997032888A1

公开(公告)日：1997-09-12

申请号：PCT/US1997003584

申请日：1997-03-07

Applicant: ISIS PHARMACEUTICALS, INC. ,  NIELSEN, Peter, E. ,  CHRISTENSEN, Leif ,  HANSEN, Henrik, Frydenlund

Inventor： ISIS PHARMACEUTICALS, INC.

IPC: C07H21/00

CPC classification number: C07H21/00

Abstract: Compositions and methods are provided for the nucleic acid mimic determination of nucleic acids. The compositions and methods may be used in the diagnosis and treatment of diseases amenable through modulation of nucleic acids which encode proteins that are implicated in disease states. In accordance with preferred embodiments, mimics are comprised of non-naturally occurring backbones to which are appended modified heterocyclics bases. Such bases preferably have sterically balky substituents 1, 2, or 3 atoms removed from the sites of attachment to the backbone.

Abstract translation: 提供了用于核酸的核酸模拟测定的组合物和方法。 组合物和方法可以用于诊断和治疗通过调节编码与疾病状态有关的蛋白质的核酸而适应的疾病。 根据优选实施方案，模拟物由非天然存在的骨架组成，其中是经修饰的杂环基团。 这样的碱优选具有从与主链连接的位点去除的空间上具有取代基的1,2或3个原子。

公开(公告)号：WO2013070298A3

公开(公告)日：2014-03-20

申请号：PCT/US2012051644

申请日：2012-08-21

Applicant: 3M INNOVATIVE PROPERTIES CO ,  CHRISTENSEN LEIF ,  SCANLAN JEROME E ,  LINDERT ANTHONY P

Inventor： CHRISTENSEN LEIF ,  SCANLAN JEROME E ,  LINDERT ANTHONY P

IPC: C01G45/12 ,  C01G51/00 ,  C01G53/00 ,  H01M4/131 ,  H01M4/1391 ,  H01M4/36 ,  H01M4/505 ,  H01M4/525 ,  H01M10/0525

CPC classification number: H01M4/505 ,  C01G53/50 ,  C01P2006/40 ,  H01M4/0471 ,  H01M4/131 ,  H01M4/1391 ,  H01M4/364 ,  H01M4/366 ,  H01M4/525 ,  H01M10/0525 ,  H01M2004/028 ,  Y02E60/122 ,  Y02P70/54

Abstract: Positive electrode for lithium-ion electrochemical cells are provided that have capacity retentions of greater than about 95% after 50 charge-discharge cycles when comparing the capacity after cycle 52 with the capacity after cycle 2 when cycled between 2.5 V and 4.7 V vs. Li/Li+ at 30°C. Compositions useful in the provided positive electrodes can have the formula, Li1+x(NiaMnbCoc)1-x O2, wherein 0.05 ≤ x ≤ 0.10, a + b + c = 1, 0.6 ≤ b/a ≤ 1.1, c/(a + b)

Abstract translation: 提供了用于锂离子电化学电池的正极，当比较循环52之后的容量与循环2之间的容量在2.5V与4.7V之间的循环时相比，在50次充放电循环之后具有大于约95％的容量保持 / Li +在30℃。 在所提供的正电极中有用的组合物可以具有式Li1 + x（NiaMnbCoc）1-xO2，其中0.05≤x≤0.10，a + b + c =1,0.6≤b/a≤1.1，c /（a + b）<0.25，a，b和c都大于零。 制造这些正电极的过程包括在850℃至925℃下烧制组合物。

公开(公告)号：WO2013007256A1

公开(公告)日：2013-01-17

申请号：PCT/DK2011/000082

申请日：2011-07-13

Applicant: WIDEX A/S ,  LUND-OLESEN, Torsten ,  KALLESØE, Christian ,  HALES, Jan, Harry ,  CHRISTENSEN, Leif, Højslet

Inventor： LUND-OLESEN, Torsten ,  KALLESØE, Christian ,  HALES, Jan, Harry ,  CHRISTENSEN, Leif, Højslet

IPC: H01M8/04 ,  H01M8/10 ,  H01M8/00

CPC classification number: H01M8/1002 ,  H01M8/04186 ,  H01M8/04201 ,  H01M8/04402 ,  H01M8/1007 ,  H01M8/1009 ,  H01M8/1011 ,  H01M8/1013 ,  H01M2008/1095 ,  H01M2250/30 ,  Y02B90/18 ,  Y02E60/522 ,  Y02E60/523 ,  Y02P70/56

Abstract: A fuel cell for a portable electronic device having a liquid fuel reservoir (100) wherein at least a part of the inner surface (103) and a part of an outer surface (104) of the fuel reservoir wall (102) are gas permeable, wherein said wall is adapted such that the area of the open parts of the inner surface (103) of the wall is larger than the area of the open parts of said outer surface (104) of the wall, wherein said wall is porous and adapted to allow gas to enter said wall and to be transported along said wall in a direction substantially parallel with the plane of the wall and to leave said wall, and wherein said wall is adapted such that the inner surface is hydrophobic. The invention further provides a portable electronic device and a method of manufacturing a liquid fuel reservoir.

Abstract translation: 一种用于具有液体燃料储存器（100）的便携式电子装置的燃料电池，其中所述内表面（103）的至少一部分和所述燃料储存器壁（102）的外表面（104）的一部分是透气的， 其中所述壁适于使得所述壁的内表面（103）的开口部分的面积大于所述壁的所述外表面（104）的开口部分的面积，其中所述壁是多孔的并且适于 以允许气体进入所述壁并且沿着基本上平行于壁的平面的方向沿所述壁传送并且离开所述壁，并且其中所述壁适于使得内表面是疏水性的。 本发明还提供一种便携式电子设备和制造液体燃料储存器的方法。