公开(公告)号：WO2006090365A3

公开(公告)日：2007-02-22

申请号：PCT/IL2006000216

申请日：2006-02-21

Applicant: YISSUM RES DEV CO ,  DOMB ABRAHAM J ,  KATZ EHUD ,  YUDOVIN-FARBER IRA ,  TARABOULOS ALBERT

Inventor： DOMB ABRAHAM J ,  KATZ EHUD ,  YUDOVIN-FARBER IRA ,  TARABOULOS ALBERT

IPC: A61K47/48

CPC classification number: A61K47/61

Abstract: The invention provides the use of polysaccharide-oligoamine conjugates, compositions comprising thereof and methods of prophylaxis and/or treatment of viral diseases and diseases and disorders associated with accumulation of amyloid fibrils (amyloidoses).

Abstract translation: 本发明提供了多糖 - 低聚木糖共轭物的使用，其组合物及其与预防和/或治疗与淀粉样蛋白原纤维（淀粉样变性）积累相关的疾病和病症的方法。

公开(公告)号：WO2006070376A1

公开(公告)日：2006-07-06

申请号：PCT/IL2006/000005

申请日：2006-01-01

Applicant: HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD. ,  YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM ,  DOMB, Abraham J. ,  WEISS, Ervin I. ,  BEYTH, Nurit ,  FARBER, Ira ,  PEREZ DAVIDI, Michael

Inventor： DOMB, Abraham J. ,  WEISS, Ervin I. ,  BEYTH, Nurit ,  FARBER, Ira ,  PEREZ DAVIDI, Michael

IPC: A01N25/12 ,  A01N33/12 ,  A01N37/12 ,  A61L27/34 ,  A61L29/08 ,  A61L31/10 ,  A61L27/16 ,  A61Q11/00 ,  A61K6/08 ,  A61L29/04 ,  A01P1/00

CPC classification number: A61K6/083 ,  A01N25/12 ,  A01N33/12 ,  A01N37/12 ,  A61K6/0008 ,  A61K6/0023 ,  A61K6/0032 ,  A61K6/0067 ,  A61L27/34 ,  A61L27/54 ,  A61L29/085 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/208 ,  A61L2300/404 ,  A61L2300/408 ,  A61L2300/624 ,  C08L39/02 ,  C08L33/08 ,  C08L5/08

Abstract: The present invention provides a particle comprising at least one aliphatic polymer having anti-microbially active quaternary ammonium groups chemically bound thereto. The particle of the invention may be used to inhibit populations of microorganisms and biofilms. Also provided are methods for the preparation of such particles and uses thereof for the inhibition of microorganisms.

Abstract translation: 本发明提供一种包含至少一种具有与其结合的抗微生物活性季铵基团的脂族聚合物的颗粒。 本发明的颗粒可用于抑制微生物和生物膜的种群。 还提供了制备这种颗粒的方法及其用于抑制微生物的用途。

公开(公告)号：WO2006090365A2

公开(公告)日：2006-08-31

申请号：PCT/IL2006/000216

申请日：2006-02-21

Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY ,  DOMB, Abraham J. ,  KATZ, Ehud ,  YUDOVIN-FARBER, Ira ,  TARABOULOS, Albert

Inventor： DOMB, Abraham J. ,  KATZ, Ehud ,  YUDOVIN-FARBER, Ira ,  TARABOULOS, Albert

IPC: A61K47/48

CPC classification number: A61K47/61

Abstract: The invention provides the use of polysaccharide-oligoamine conjugates, compositions comprising thereof and methods of prophylaxis and/or treatment of viral diseases and diseases and disorders associated with accumulation of amyloid fibrils (amyloidoses).

Abstract translation: 本发明提供了多糖 - 寡聚胺缀合物的使用，其组合物及其与预防和/或治疗与淀粉样蛋白原纤维（淀粉样变性）积累相关的疾病和病症的方法。