公开(公告)号：WO2006070376A1

公开(公告)日：2006-07-06

申请号：PCT/IL2006/000005

申请日：2006-01-01

Applicant: HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD. ,  YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM ,  DOMB, Abraham J. ,  WEISS, Ervin I. ,  BEYTH, Nurit ,  FARBER, Ira ,  PEREZ DAVIDI, Michael

Inventor： DOMB, Abraham J. ,  WEISS, Ervin I. ,  BEYTH, Nurit ,  FARBER, Ira ,  PEREZ DAVIDI, Michael

IPC: A01N25/12 ,  A01N33/12 ,  A01N37/12 ,  A61L27/34 ,  A61L29/08 ,  A61L31/10 ,  A61L27/16 ,  A61Q11/00 ,  A61K6/08 ,  A61L29/04 ,  A01P1/00

CPC classification number: A61K6/083 ,  A01N25/12 ,  A01N33/12 ,  A01N37/12 ,  A61K6/0008 ,  A61K6/0023 ,  A61K6/0032 ,  A61K6/0067 ,  A61L27/34 ,  A61L27/54 ,  A61L29/085 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/208 ,  A61L2300/404 ,  A61L2300/408 ,  A61L2300/624 ,  C08L39/02 ,  C08L33/08 ,  C08L5/08

Abstract: The present invention provides a particle comprising at least one aliphatic polymer having anti-microbially active quaternary ammonium groups chemically bound thereto. The particle of the invention may be used to inhibit populations of microorganisms and biofilms. Also provided are methods for the preparation of such particles and uses thereof for the inhibition of microorganisms.

Abstract translation: 本发明提供一种包含至少一种具有与其结合的抗微生物活性季铵基团的脂族聚合物的颗粒。 本发明的颗粒可用于抑制微生物和生物膜的种群。 还提供了制备这种颗粒的方法及其用于抑制微生物的用途。

公开(公告)号：WO2008029386A3

公开(公告)日：2008-03-13

申请号：PCT/IL2007/001024

申请日：2007-08-15

Applicant: DENTAL BIOTECHNOLOGY LTD. ,  PEREZ-DAVIDI, Michael Moshe ,  STERER, Nir ,  WEISS, Ervin Itzchak ,  DOMB, Avraham Jacob

Inventor： PEREZ-DAVIDI, Michael Moshe ,  STERER, Nir ,  WEISS, Ervin Itzchak ,  DOMB, Avraham Jacob

IPC: A61K9/14

Abstract: Devices and methods for a palatal patch include a tablet or strip having a bioadhesive component and an active component. The bioadhesive component allows for the palatal patch to be attached to an upper palate, and for the active component to be released into the oral cavity and/or GI tract. Compositions for the active component include compositions for treatment of halitosis, anti-acids, vitamins, anti-smoking agents, and others. A composition for treatment of halitosis includes at least one of Echinacea, Lavender, Mastic Gum and Sage. A device for delivery of the palatal patch to the upper palate includes a housing and a piston, the piston having a holder for the palatal patch, and wherein the piston may be configured to move distally so as to delivery the palatal patch to the upper palate.

公开(公告)号：WO2008029386A2

公开(公告)日：2008-03-13

申请号：PCT/IL2007001024

申请日：2007-08-15

Applicant: DENTAL BIOTECHNOLOGY LTD ,  PEREZ-DAVIDI MICHAEL MOSHE ,  STERER NIR ,  WEISS ERVIN ITZCHAK ,  DOMB AVRAHAM JACOB

Inventor： PEREZ-DAVIDI MICHAEL MOSHE ,  STERER NIR ,  WEISS ERVIN ITZCHAK ,  DOMB AVRAHAM JACOB

IPC: A61K8/97

CPC classification number: A61Q11/00 ,  A61K8/0208 ,  A61K8/97 ,  A61K9/006 ,  A61K36/22 ,  A61K36/28 ,  A61K36/53 ,  A61K36/537 ,  A61K2300/00

Abstract: Devices and methods for a palatal patch include a tablet or strip having a bioadhesive component and an active component. The bioadhesive component allows for the palatal patch to be attached to an upper palate, and for the active component to be released into the oral cavity and/or GI tract. Compositions for the active component include compositions for treatment of halitosis, anti-acids, vitamins, anti-smoking agents, and others. A composition for treatment of halitosis includes at least one of Echinacea, Lavender, Mastic Gum and Sage. A device for delivery of the palatal patch to the upper palate includes a housing and a piston, the piston having a holder for the palatal patch, and wherein the piston may be configured to move distally so as to delivery the palatal patch to the upper palate.

Abstract translation: 用于腭贴片的装置和方法包括具有生物粘附成分和活性成分的片剂或条带。 生物粘附组分允许腭贴附接到上腭，并且活性成分被释放到口腔和/或胃肠道中。 活性组分的组合物包括用于治疗口臭，抗酸，维生素，抗吸烟剂等的组合物。 用于治疗口臭的组合物包括紫锥花，薰衣草，乳香和圣人中的至少一种。 用于将腭贴片递送到上腭的装置包括壳体和活塞，活塞具有用于腭部贴片的保持器，并且其中活塞可以被配置为向远侧移动，以将腭贴片输送到上腭 。