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1.发明申请3-(4-HETEROARYLCYCLOHEXYLAMINO) CYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS 审中-公开作为化合物受体的调节剂的3-（4-异丙基环己基氨基）环戊烷羧酸
公开(公告)号：WO2005115392A8
公开(公告)日：2006-10-05
申请号：PCT/US2005016318
申请日：2005-05-10
Applicant: INCYTE CORP , XUE CHU-BIAO , ZHENG CHANGSHENG , CAO GANFENG , FENG HAO , XIA MICHAEL , ANAND RAJAN , GLENN JOSEPH , METCALF BRIAN
Inventor： XUE CHU-BIAO , ZHENG CHANGSHENG , CAO GANFENG , FENG HAO , XIA MICHAEL , ANAND RAJAN , GLENN JOSEPH , METCALF BRIAN
IPC: A61K31/47 , A61K31/4745 , C07D217/00 , C07D217/06 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/12 , C07D471/02 , C07D471/04
CPC classification number: C07D471/04 , C07D217/06 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/12
Abstract: The present invention is directed to compounds of Formula (I) which are modulators of chemokine receptors. The compounds of the invention, and compositions thereof, are useful in the treatment of diseases related to chemokine receptor expression and/or activity.
Abstract translation: 本发明涉及作为趋化因子受体调节剂的式（I）化合物。 本发明的化合物及其组合物可用于治疗与趋化因子受体表达和/或活性相关的疾病。
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2.发明申请FLAME RESISTANT FABRICS HAVING HIGH RESISTANCE TO PILLING, AND METHODS OF MAKING SAME 审中-公开具有高抗药性的耐火织物及其制造方法
公开(公告)号：WO2005040469A3
公开(公告)日：2006-06-29
申请号：PCT/US2004025948
申请日：2004-08-11
Applicant: MILLIKEN & CO , CAMPBELL PAUL C , DEMOTT PHILLIP R , GLENN JOSEPH B , SASSER KIMILA C
Inventor： CAMPBELL PAUL C , DEMOTT PHILLIP R , GLENN JOSEPH B , SASSER KIMILA C
CPC classification number: D03D15/12 , A41D31/0022 , Y10T442/30
Abstract: A flame resistant fabric having a high level of pilling resistance and good strength characteristics is described. In addition, a method of making the fabric is also described.
Abstract translation: 描述了具有高水平的起球抗性和良好强度特性的阻燃织物。 此外，还描述了制造织物的方法。
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3.发明申请3-(4-HETEROARYLCYCLOHEXZLAMINO) CZCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS 审中-公开作为化合物受体的调节剂的3-（4-异丙基环己基）氨基苯甲酰胺
公开(公告)号：WO2005115392A3
公开(公告)日：2006-02-02
申请号：PCT/US2005016318
申请日：2005-05-10
Applicant: INCYTE CORP , XUE CHU-BIAO , ZHENG CHANGSHENG , CAO GANFENG , FENG HAO , XIA MICHAEL , ANAND RAJAN , GLENN JOSEPH , METCALF BRIAN
Inventor： XUE CHU-BIAO , ZHENG CHANGSHENG , CAO GANFENG , FENG HAO , XIA MICHAEL , ANAND RAJAN , GLENN JOSEPH , METCALF BRIAN
IPC: A61K31/47 , A61K31/4745 , C07D217/06 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/12 , C07D471/02 , C07D471/04 , C07D217/00
CPC classification number: C07D471/04 , C07D217/06 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/12
Abstract: The present invention is directed to compounds of Formula (I) which are modulators of chemokine receptors. The compounds of the invention, and compositions thereof, are useful in the treatment of diseases related to chemokine receptor expression and/or activity.
Abstract translation: 本发明涉及作为趋化因子受体调节剂的式（I）化合物。 本发明的化合物及其组合物可用于治疗与趋化因子受体表达和/或活性相关的疾病。
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4.发明申请FLAME RESISTANT FABRICS HAVING HIGH RESISTANCE TO PILLING, AND METHODS OF MAKING SAME 审中-公开具有高抗药性的耐火织物及其制造方法
公开(公告)号：WO2005040469A2
公开(公告)日：2005-05-06
申请号：PCT/US2004/025948
申请日：2004-08-11
Applicant: MILLIKEN & COMPANY , CAMPBELL, Paul, C. , DEMOTT, Phillip, R. , GLENN, Joseph, B. , SASSER, Kimila, C.
Inventor： CAMPBELL, Paul, C. , DEMOTT, Phillip, R. , GLENN, Joseph, B. , SASSER, Kimila, C.
IPC: D03D
CPC classification number: D03D15/12 , A41D31/0022 , Y10T442/30
Abstract: A flame resistant fabric having a high level of pilling resistance and good strength characteristics is described. In addition, a method of making the fabric is also described.
Abstract translation: 描述了具有高水平的起球抗性和良好强度特性的阻燃织物。 此外，还描述了制造织物的方法。
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公开(公告)号：WO2003078118A1
公开(公告)日：2003-09-25
申请号：PCT/US2003/007777
申请日：2003-03-12
Applicant: GLENN, Joseph, K.
Inventor： GLENN, Joseph, K.
IPC: B27F7/00
CPC classification number: B27F7/003 , B27M3/0073
Abstract: A portable roof panel structure assembly mechanism (100) that may be transported to a construction site and that is used to automatically assemble roof panel structures at the site. The assembly mechanism includes a purlin feeder (102), subpurlin clamping mechanisms (106) and feeders (104), and a diaphragm feeder (108). The purlin feeder (102) lifts a purlin into position, and advances the purlin into an assembly station (110). The subpurlin feeders (104) insert a subpurlin into each of a plurality of subpurlin clamping mechanisms, and the clamping mechanisms advance into the assembly station (110) and hold the subpurlins against the section of the purlin that has been advanced. The diaphragm feeder (108) places a diaphragm onto the subpurlins and the purlin at the assembly station (110). The components are attached by automatic nailers.
Abstract translation: 一种便携式屋顶板结构组装机构（100），其可以运输到施工现场并用于在现场自动组装屋顶板结构。 组装机构包括pur条进料器（102），亚螺旋夹紧机构（106）和进料器（104）以及隔膜进料器（108）。 pur条进料器（102）将pur条提升到适当的位置，并将pur条推进装配站（110）。 脊髓输送器（104）将亚急性髓鞘插入到多个亚型螺钉夹持机构中的每一个中，并且夹紧机构前进到组装工位（110）中，并且将该副螺旋束紧靠在已经前进的pur条部分。 隔膜进料器（108）将膜片放置在装配站（110）上的子纸浆和pur条上。 组件通过自动钉枪连接。
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Patent Agency Ranking6.发明申请HETEROCYCLIC-SUBSTITUTED PYRROLOPYRIDINES AND PYRROLOPYRIMIDINES AS JAK INHIBITORS 审中-公开作为JAK抑制剂的杂环取代的吡咯烷酮和吡咯烷酮
公开(公告)号：WO2012068440A1
公开(公告)日：2012-05-24
申请号：PCT/US2011/061351
申请日：2011-11-18
Applicant: INCYTE CORPORATION , RODGERS, James, D. , ZHU, Wenyu , GLENN, Joseph
Inventor： RODGERS, James, D. , ZHU, Wenyu , GLENN, Joseph
IPC: C07D487/04
CPC classification number: C07D487/04
Abstract: The present invention provides heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines of Formula I: wherein X, Y, Z, L, A, R 5 , n, m, and r are defined above, as well as their compositions and methods of use, that modulate the activity of Janus kinases (JAKs) and are useful in the treatment of diseases related to the activity of JAKs including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.
Abstract translation: 本发明提供式I的杂环取代的吡咯并吡啶和吡咯并嘧啶：其中X，Y，Z，L，A，R 5，n，m和r如上所定义，以及它们的组合物和使用方法， Janus激酶（JAKs）的活性，并且可用于治疗与JAK的活性相关的疾病，包括例如炎症性疾病，自身免疫性疾病，癌症和其它疾病。
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7.发明申请
公开(公告)号：WO2006004684A3
公开(公告)日：2006-10-05
申请号：PCT/US2005022793
申请日：2005-06-27
Applicant: INCYTE CORP , XUE CHU-BIAO , ZHENG CHANGSHENG , FENG HAO , XIA MICHAEL , GLENN JOSEPH , CAO GANFENG , METCALF BRIAN W
Inventor： XUE CHU-BIAO , ZHENG CHANGSHENG , FENG HAO , XIA MICHAEL , GLENN JOSEPH , CAO GANFENG , METCALF BRIAN W
IPC: A61K31/497 , A61K31/44 , A61K31/445 , C07D241/04 , C07D401/10 , C07D403/14
CPC classification number: C07D405/14 , C07D309/14 , C07D405/12
Abstract: The present invention is directed to compounds of Formula (I): which are modulators of chemokine receptors. The compounds of the invention, and compositions thereof, are useful in the treatment of diseases related to chemokine receptor expression and/or activity.
Abstract translation: 本发明涉及式（I）化合物：其是趋化因子受体的调节剂。 本发明的化合物及其组合物可用于治疗与趋化因子受体表达和/或活性相关的疾病。
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公开(公告)号：WO2007015744A1
公开(公告)日：2007-02-08
申请号：PCT/US2006/027333
申请日：2006-07-14
Applicant: INCYTE CORPORATION , CAO, Ganfeng , XUE, Chu-Biao , ANAND, Rajan , HUANG, Taisheng , KONG, Ling , GLENN, Joseph , FENG, Hao
Inventor： CAO, Ganfeng , XUE, Chu-Biao , ANAND, Rajan , HUANG, Taisheng , KONG, Ling , GLENN, Joseph , FENG, Hao
IPC: C07D333/10 , C07D409/12 , A61K31/381 , A61K31/506 , A61K31/4436
CPC classification number: C07D333/38 , C07D409/12 , C07D413/12 , C07D417/12
Abstract: The present invention relates to modulators of HM74a receptor, and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with HM74a receptor.
Abstract translation: 本发明涉及HM74a受体的调节剂及其药物组合物。 本发明的化合物可用于治疗与HM74a受体相关的各种疾病。
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9.发明申请
公开(公告)号：WO2005101838A8
公开(公告)日：2006-05-11
申请号：PCT/US2005012265
申请日：2005-04-12
Applicant: XUE CHU-BIAO , CAO GANFENG , HUANG TAISHENG , CHEN LIHUA , ZHANG KE , WANG ANLAI , MELONI DAVID , ANAND RAJAN , GLENN JOSEPH , METCALF BRIAN , INCYTE CORP
Inventor： XUE CHU-BIAO , CAO GANFENG , HUANG TAISHENG , CHEN LIHUA , ZHANG KE , WANG ANLAI , MELONI DAVID , ANAND RAJAN , GLENN JOSEPH , METCALE BRIAN
IPC: A61K31/496 , A61K45/06 , C07D401/06 , C07D401/14 , C07D417/14 , C07D471/04
CPC classification number: C07D401/14 , A61K31/496 , A61K31/502 , A61K31/506 , A61K45/06 , C07D401/06 , C07D417/14 , C07D471/04 , A61K2300/00
Abstract: The present invention relates to compounds of Formula (I): wherein variable substituents are defined herein, that modulate the activity of or bind to chemokine receptors such as CCR5. In some embodiments, the compounds of the invention are selective for CCR5. The compounds can be used, for example, to treat diseases associated with chemokine receptor expression or activity such as inflammatory diseases, immune diseases and viral infections.
Abstract translation: 本发明涉及式（I）的化合物：其中可变取代基在本文中定义，其调节趋化因子受体如CCR5的活性或与其结合。 在一些实施方案中，本发明的化合物对CCR5是选择性的。 该化合物可用于例如治疗与趋化因子受体表达或活性相关的疾病，例如炎性疾病，免疫疾病和病毒感染。
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10.发明申请
公开(公告)号：WO2006004741A3
公开(公告)日：2006-05-04
申请号：PCT/US2005022909
申请日：2005-06-27
Applicant: INCYTE CORP , XUE CHU-BIAO , ZHENG CHANGSHENG , FENG HAO , XIA MICHAEL , GLENN JOSEPH , CAO GANFENG , METCALF BRIAN W
Inventor： XUE CHU-BIAO , ZHENG CHANGSHENG , FENG HAO , XIA MICHAEL , GLENN JOSEPH , CAO GANFENG , METCALF BRIAN W
IPC: A61K31/4433 , A61K31/453 , A61K31/496 , C07D405/12 , C07D405/14
CPC classification number: C07D309/14 , C07D405/12 , C07D405/14
Abstract: The present invention is directed to compounds of Formula (I) : which are modulators of chemokine receptors. The compounds of the invention, and compositions thereof, are useful in the treatment of diseases related to chemokine receptor expression and/or activity.
Abstract translation: 本发明涉及式（I）的化合物：其是趋化因子受体的调节剂。 本发明的化合物及其组合物可用于治疗与趋化因子受体表达和/或活性相关的疾病。
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