公开(公告)号：WO1998024819A1

公开(公告)日：1998-06-11

申请号：PCT/SE1997002035

申请日：1997-12-05

Applicant: PHARMACIA & UPJOHN AB ,  BRANDT, Ragnhild ,  BECK, Olof ,  HELANDER, Anders ,  JÖNSSON, Rose-Marie ,  UNGER, Eric ,  BORG, Stefan ,  ÅKERBLOM, Eva

Inventor： PHARMACIA & UPJOHN AB

IPC: C07K16/44

CPC classification number: C07H17/02 ,  C07K16/44 ,  Y10T436/14 ,  Y10T436/145555 ,  Y10T436/17 ,  Y10T436/173845 ,  Y10T436/203332 ,  Y10T436/25

Abstract: Antibody specific for a 5-HTOL compound. A glucuronide with 5-hydroxytryptophol (5-HTOL) characterized in that it comprises the structure of the beta -glucuronide between the 5-hydroxy group of 5-HTOL and D-glucopyranosiduronic acid. An immunoassay and a diagnostic method utilizing the immunoassay wherein a 5-hydroxytryptophol (5-HTOL) compound is determined by the use of an antibody specific for a 5-HTOL compound is used.

Abstract translation: 针对5-HTOL化合物的抗体。 具有5-羟基三苯乙醇（5-HTOL）的葡糖苷酸，其特征在于其包含5-羟基5-HTOL和D-吡喃葡萄糖苷二糖酸之间的β-葡萄糖醛酸苷结构。 使用免疫测定法和诊断方法，其中使用5-羟色胺（5-HTOL）化合物通过使用对5-HTOL化合物特异的抗体来测定。