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    SURFACE GRAFTED CONJUGATED POLYMERS
    4.
    发明申请
    SURFACE GRAFTED CONJUGATED POLYMERS 审中-公开
    表面接合聚合物

    公开(公告)号：WO2008143731A2

    公开(公告)日：2008-11-27

    申请号：PCT/US2008002756

    申请日：2008-02-29

    Applicant: UNIV FLORIDA ,  WHITTEN DAVID G ,  CHEMBURU SIREESHA ,  CORBITT THOMAS ,  ISTA LINNEA ,  LOPEZ GABRIEL ,  SCHANZE KIRK S ,  OGAWA MOTOKATSU

    Inventor： WHITTEN DAVID G ,  CHEMBURU SIREESHA ,  CORBITT THOMAS ,  ISTA LINNEA ,  LOPEZ GABRIEL ,  SCHANZE KIRK S ,  OGAWA MOTOKATSU

    IPC: C07K17/08 ,  C12Q1/68 ,  G01N33/53

    CPC classification number: C07K17/08 ,  C07K1/1077 ,  G01N33/542 ,  G01N33/54313 ,  Y10T436/14 ,  Y10T436/141111 ,  Y10T436/142222 ,  Y10T436/143333 ,  Y10T436/144444 ,  Y10T436/145555 ,  Y10T436/146666 ,  Y10T436/147777

    Abstract: A surface grafted conjugated polyelectrolyte (CPE) is formed by coupling a CPE by a coupling moiety to the surface of a substrate. The substrate can be of any shape and size, and for many uses of the surface grafted CPE, it is advantageous that the substrate is a nanoparticle or microparticle. Surface grafted CPEs are presented that use silica particles as the substrate, where a modified silane coupling agent connects the surface to the CPE by a series of covalent bonds. Two methods of preparing the surface grafted CPEs are presented. One method involve the inclusion of the surface is modified by the coupling agent and condensed with monomers that form the CPE in a grafted state to the substrate. A second method involves the formation of a CPE with terminal groups that are complimentary to functionality that has been placed on the surface of the substrate by reaction with a coupling agent. The surface grafted CPEs are also described for use as biosensors and biocides.

    Abstract translation: 表面接枝共轭聚电解质（CPE）通过将CPE通过偶联部分偶联到基材的表面而形成。 衬底可以是任何形状和尺寸，并且对于表面接枝CPE的许多用途，衬底是纳米颗粒或微粒是有利的。 提出了使用二氧化硅颗粒作为底物的表面接枝CPE，其中改性的硅烷偶联剂通过一系列共价键将表面连接到CPE。 提出了两种制备表面接枝CPE的方法。 一种方法是包含表面被偶联剂改性并与接枝状态的形成CPE的单体冷凝。 第二种方法包括形成具有末端基团的CPE，其与通过与偶联剂反应放置在基底表面上的官能度互补。 表面接枝的CPE也被描述为用作生物传感器和杀生物剂。

    PHOTOCHROMIC AND ELECTROCHROMIC COMPOUNDS AND SYNTHESIS AND USE THEREOF
    6.
    发明申请
    PHOTOCHROMIC AND ELECTROCHROMIC COMPOUNDS AND SYNTHESIS AND USE THEREOF 审中-公开
    光致变色和电化学化合物及其合成及其用途

    公开(公告)号：WO2006125317A1

    公开(公告)日：2006-11-30

    申请号：PCT/CA2006/000862

    申请日：2006-05-25

    Applicant: SIMON FRASER UNIVERSITY ,  BRANDA, Neil R. ,  WUESTENBERG, Bettina ,  LEMIEUX, Vincent ,  ADAMS, Michael ,  GAUTHIER, Simon

    Inventor： BRANDA, Neil R. ,  WUESTENBERG, Bettina ,  LEMIEUX, Vincent ,  ADAMS, Michael ,  GAUTHIER, Simon

    IPC: C07D333/06 ,  C07D333/52 ,  C09K9/02

    CPC classification number: C07D333/18 ,  C07D333/22 ,  C07D333/24 ,  C07D333/28 ,  C07D333/78 ,  C07D409/08 ,  C07D409/14 ,  C09K9/02 ,  C09K2211/1007 ,  C09K2211/1092 ,  Y10T436/14 ,  Y10T436/142222

    Abstract: Novel photochromic and electrochromic hexadiene compounds are described. The compounds are reversibly convertible between ring-open and ring-closed isomeric forms as indicated in structures I(o) and I(c) below. (See formula in original abstract of application) The conversion between the different isomeric forms may be induced by light or electricity. In one embodiment the compounds may include a charge transfer moiety including electron donor and acceptor groups. The electron donor and acceptor are linearly conjugated in the ring-open form to enable electron transfer but are electrically insulated in the ring-closed form. Methods for synthesizing the compounds from photochemically and/or electrically inert precursors are also described. For example, the photoresponsive compounds may be synthesized by reacting diene precursors with dienophiles in a condensation reaction. The compounds may be utilized in reactivity-gated photochromic or electrochromic applications. In one embodiment of the invention, compounds of the invention may be used in a method to selectively release a releasable agent, such as a small molecule. According to this method, a photochemically inert precursor compound is reacted with the releasable agent to form a carrier compound comprising a switching moiety, the switching moiety being reversibly convertible between a thermally unstable form and a thermally stable form. The switching moiety may be selectively converted between the first and second forms to cause controlled release of the releasable agent from the carrier compound.

    Abstract translation: 描述了新的光致变色和电致变色己二烯化合物。 如下文结构I（o）和I（c）所示，化合物在开环和闭环异构体形式之间是可逆转化的。 （参见原始应用摘要中的公式）不同异构形式之间的转换可能是由光或电引起的。 在一个实施方案中，化合物可以包括电子转移部分，包括电子给体和受体基团。 电子给体和受体以开环形式线性共轭以使电子转移，但以闭环形式电绝缘。 还描述了从光化学和/或电惰性前体合成化合物的方法。 例如，光响应化合物可以通过二烯前体与缩合反应中的亲二烯体反应来合成。 化合物可用于反应性门控的光致变色或电致变色应用中。 在本发明的一个实施方案中，本发明的化合物可用于选择性释放可释放剂如小分子的方法。 根据该方法，将光化学惰性的前体化合物与可释放试剂反应形成包含切换部分的载体化合物，该切换部分在热不稳定形式和热稳定形式之间可逆地转化。 切换部分可以在第一和第二形式之间选择性地转化以引起可释放试剂从载体化合物的受控释放。

    シガトキシンＣＴＸ３Ｃを検出するサンドイッチ測定キット類
    8.
    发明申请
    シガトキシンＣＴＸ３Ｃを検出するサンドイッチ測定キット類 审中-公开
    用于检测白蛋白CTX3C的三明治测定试剂盒

    公开(公告)号：WO2003076934A1

    公开(公告)日：2003-09-18

    申请号：PCT/JP2003/002782

    申请日：2003-03-10

    Applicant: 科学技術振興事業団 ,  平間 正博 ,  大栗 博毅 ,  藤井 郁雄 ,  円谷 健

    Inventor： 平間 正博 ,  大栗 博毅 ,  藤井 郁雄 ,  円谷 健

    IPC: G01N33/53

    CPC classification number: G01N33/5308 ,  C07D263/58 ,  C07K16/14 ,  C07K16/44 ,  Y10T436/14

    Abstract: Sandwich assay kits for detecting shigatoxins which comprise a combination of a monoclonal antibody reacting specifically with shigatoxin CTX3C produced by a hybridoma 3D11 (ACCESSION NUMBER FERM BP-8293) with another monoclonal antibody reacting specifically with shigatoxin CTX3C produced by a hybridoma 10C9 (ACCESSION NUMBER FERM BP-8292), in particular, a combination wherein one of these monoclonal antibody is bound to a labeling compound to give a labeled monoclonal antibody and then combined with the other monoclonal antibody which is unlabeled.

    Abstract translation: 用于检测志贺毒素的三明治测定试剂盒，其包含由杂交瘤3D11（ACCESSION NUMBER FERM BP-8293）与由杂交瘤10C9（ACCESSION NUMBER FERM）产生的与毒蕈碱CTX3C特异性反应的另一种单克隆抗体特异性地与由俄罗斯的杂交瘤3D11（ACCESSION NUMBER FERM BP-8293）产生的叶黄素CTX3C特异性反应的单克隆抗体的组合 BP-8292），特别是其中这些单克隆抗体之一与标记化合物结合以得到标记的单克隆抗体，然后与未标记的其他单克隆抗体组合的组合。

    FLUOROMETRIC CONTROL OF AROMATIC OXYGEN SCA VENGERS IN A BOILER SYSTEM
    9.
    发明申请
    FLUOROMETRIC CONTROL OF AROMATIC OXYGEN SCA VENGERS IN A BOILER SYSTEM 审中-公开
    锅炉系统中芳烃氧化物过滤器的荧光光度控制

    公开(公告)号：WO0247455A2

    公开(公告)日：2002-06-20

    申请号：PCT/US0146369

    申请日：2001-12-04

    Applicant: ONDEO NALCO CO

    Inventor： DAVIS BARBARA H ,  LINK LINDA M ,  HOOTS JOHN E

    IPC: C02F1/58 ,  F22B37/56 ,  G01N21/64 ,  G01N

    CPC classification number: G01N21/643 ,  C02F2103/023 ,  C02F2303/08 ,  G01N21/64 ,  Y10T436/12 ,  Y10T436/14 ,  Y10T436/209163

    Abstract: A method of automatically controlling the addition rate of Fresh Oxygen Scavenger Product and Ultimate Oxygen Scavenger Product to a Boiler System is described and claimed. The method is based on the inherent fluorometric properties of certain Fresh Oxygen Scavenger Products and certain Ultimate Oxygen Scavengers in their reduced (unreacted) form and also, for the Ultimate Oxygen Scavengers, in their oxidized (reacted) form. It has also been found possible to enhance the fluorescent signal of certain Oxygen Scavengers by adding a borate buffer to the sample stream. By using the method of the instant claimed invention it is now possible to improve the overall control of Boiler Systems using certain Fresh Oxygen Scavenger Products and certain Ultimate Oxygen Scavenger Products.

    Abstract translation: 描述并要求保护一种自动控制新鲜除氧剂产物和最终除氧剂产物在锅炉系统中的添加速率的方法。 该方法基于某些新鲜除氧剂产品和某些最终除氧剂以其还原（未反应）形式以及对于最终除氧剂以其氧化（反应）形式存在的固有荧光性质。 还发现通过向样品流中加入硼酸盐缓冲剂可以增强某些除氧剂的荧光信号。 通过使用本发明的方法，现在可以改进使用某些新鲜除氧剂产品和某些最终除氧剂产品的锅炉系统的整体控制。

    SYSTEM AND METHOD OF INFRARED MATRIX-ASSISTED LASER DESORPTION/IONIZATION MASS SPECTROMETRY IN POLYACRYLAMIDE GELS
    10.
    发明申请
    SYSTEM AND METHOD OF INFRARED MATRIX-ASSISTED LASER DESORPTION/IONIZATION MASS SPECTROMETRY IN POLYACRYLAMIDE GELS 审中-公开
    红外线辅助激光吸收/离子质谱法在聚丙烯酰胺凝胶中的体系和方法

    公开(公告)号：WO02014849A1

    公开(公告)日：2002-02-21

    申请号：PCT/US2001/025658

    申请日：2001-08-16

    IPC: G01N1/00 ,  G01N19/06 ,  G01N27/447 ,  H01J49/04 ,  H01J49/16 ,  G01N24/00

    CPC classification number: H01J49/164 ,  G01N1/22 ,  G01N19/06 ,  G01N27/44717 ,  H01J49/0468 ,  Y10T436/14 ,  Y10T436/141111 ,  Y10T436/142222 ,  Y10T436/143333 ,  Y10T436/24 ,  Y10T436/25 ,  Y10T436/25125 ,  Y10T436/2525 ,  Y10T436/25875

    Abstract: A system and method for desorption and ionization of analytes in an ablation medium. In one embodiment, the method includes the steps of preparing a sample having analytes in a medium including at least one component, freezing the sample at a sufficiently low temperature so that at least part of the sample has a phase transition, and irradiating the frozen sample with short-pulse radiation to cause medium ablation and desorption and ionization of the analytes. The method further includes the steps of selecting a resonant vibrational mode of at least one component of the medium and selecting an energy source tuned to emit radiation substantially at the wavelength of the selected resonant vibrational mode. The medium is an electrophoresis medium having polyacrylamide. In one embodiment, the energy source is a laser, where the laser can be a free electron laser tunable to generate short-pulse radiation. Alternatively, the laser can be a solid state laser tunable to generate short-pulse radiation. The laser can emit light at various ranges of wavelength.

    Abstract translation: 一种消融介质中分析物解吸和电离的系统和方法。 在一个实施方案中，该方法包括以下步骤：制备在包含至少一种组分的培养基中具有分析物的样品，在足够低的温度下冷冻样品，使得至少部分样品具有相变，并照射冷冻样品 用短脉冲辐射引起分析物的中等消融和解吸和电离。 该方法还包括以下步骤：选择介质的至少一个分量的谐振振动模式，并且选择被调谐以发射基本上在所选共振振动模式的波长处的辐射的能量源。 该介质是具有聚丙烯酰胺的电泳介质。 在一个实施例中，能量源是激光器，其中激光器可以是可调谐的自由电子激光器以产生短脉冲辐射。 或者，激光器可以是可调谐的固态激光器，以产生短脉冲辐射。 激光器可以发射各种波长范围的光。

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