利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

21 条记录 (耗时 0.02 秒)

    ANTIGEN ARRAYS PRESENTING IL-5, IL-3 OR EOTAXIN FOR TREATMENT OF ALLERGIC EOSINOPHILIC DISEASES
    3.
    发明申请
    ANTIGEN ARRAYS PRESENTING IL-5, IL-3 OR EOTAXIN FOR TREATMENT OF ALLERGIC EOSINOPHILIC DISEASES 审中-公开

    公开(公告)号：WO2003040164A3

    公开(公告)日：2003-05-15

    申请号：PCT/EP2002/012455

    申请日：2002-11-07

    申请人： CYTOS BIOTECHNOLOGY AG ,  BACHMANN, Martin ,  JENNINGS, Gary ,  SONDEREGGER, Ivo

    发明人： BACHMANN, Martin ,  JENNINGS, Gary ,  SONDEREGGER, Ivo

    IPC分类号： A61K39/39

    摘要： The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular an array comprising a protein or peptide of IL-5, IL-13 or eotaxin. More specifically, the invention provides a composition comprising a virus-like particle and at least one protein, or peptide of IL-5, IL-13 and/or eotaxin bound thereto. The invention also provides a process for producing the conjugates and the ordered and repetitive arrays, respectively. The compositions of the invention are useful in the production of vaccines for the treatment of allergic diseases with an eosinophilic component and as a pharmaccine to prevent or cure allergic diseases with an eosinophilic component and to efficiently induce immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune responses within the indicated context.

    CARRIER CONJUGATES OF GNRH-PEPTIDES
    4.
    发明申请
    CARRIER CONJUGATES OF GNRH-PEPTIDES 审中-公开
    GNRH-PEPTIDES的载体结合物

    公开(公告)号：WO2006027300A2

    公开(公告)日：2006-03-16

    申请号：PCT/EP2005/053858

    申请日：2005-08-04

    申请人： CYTOS BIOTECHNOLOGY AG ,  BACHMANN, Martin ,  FULURIJA, Alma ,  JENNINGS, Gary ,  MEIJERINK, Edwin

    发明人： BACHMANN, Martin ,  FULURIJA, Alma ,  JENNINGS, Gary ,  MEIJERINK, Edwin

    IPC分类号： A61K39/385

    CPC分类号： C07K7/06 ,  A61K39/0006 ,  A61K39/0011 ,  A61K39/39 ,  A61K2039/5258 ,  A61K2039/55516 ,  A61K2039/6075 ,  C07K7/08 ,  C07K7/23

    摘要： The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising a virus like particle (VLP) and at least one GnRH peptide or fragment or variant thereof linked thereto. The invention also provides a process for producing the composition. The compositions of the invention are useful in the production of vaccines for the treatment of GnRH-related diseases and conditions and to efficiently induce immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self- specific immune responses within the indicated context.

    摘要翻译： 本发明涉及分子生物学，病毒学，免疫学和医学领域。 本发明提供包含病毒样颗粒（VLP）和至少一种与其连接的GnRH肽或其片段或变体的组合物。 本发明还提供了一种制备该组合物的方法。 本发明的组合物可用于生产用于治疗GnRH相关疾病和病症并有效诱导免疫应答，特别是抗体应答的疫苗。 此外，本发明的组合物特别可用于在指定的上下文中有效诱导自身特异性免疫应答。

    NERVE GROWTH FACTOR CONJUGATES AND USES THEREOF
    5.
    发明申请
    NERVE GROWTH FACTOR CONJUGATES AND USES THEREOF 审中-公开

    公开(公告)号：WO2009080823A3

    公开(公告)日：2009-07-02

    申请号：PCT/EP2008/068209

    申请日：2008-12-22

    申请人： CYTOS BIOTECHNOLOGY AG ,  BACHMANN, Martin ,  JENNINGS, Gary ,  RÖHN, Till

    发明人： BACHMANN, Martin ,  JENNINGS, Gary ,  RÖHN, Till

    IPC分类号： A61K38/18 ,  C07K14/48

    摘要： The present invention is in the fields of medicine, public health, immunology, molecular biology and virology. The invention provides composition comprising a virus-like particle (VLP) linked to at least one antigen, wherein said antigen is NGF antigen. The invention also provides a process for producing the composition. The compositions of this invention are useful in the production of vaccines, in particular, for the treatment of pain. Moreover, the compositions of the invention induce efficient immune responses, in particular antibody responses.

    MEANS AND METHODS FOR THE TREATMENT AND PREVENTION OF ALLERGIC DISEASES
    6.
    发明申请
    MEANS AND METHODS FOR THE TREATMENT AND PREVENTION OF ALLERGIC DISEASES 审中-公开
    治疗和预防过敏性疾病的方法和方法

    公开(公告)号：WO2007071402A1

    公开(公告)日：2007-06-28

    申请号：PCT/EP2006/012322

    申请日：2006-12-20

    申请人： JADO TECHNOLOGIES GMBH ,  BRAXMEIER, Tobias ,  FRIEDRICHSON, Tim ,  JENNINGS, Gary

    发明人： BRAXMEIER, Tobias ,  FRIEDRICHSON, Tim ,  JENNINGS, Gary

    IPC分类号： A61K31/14

    CPC分类号： A61K31/14

    摘要： The present invention relates of the use of certain inner ionic (zwitter ionic) phospholipids, phosphonolipids and phosphate derivatives for the preparation of a pharmaceutical composition for the treatment, prevention and/or amelioration of an immunological disorder related to mast cell sensitization and/or activation. Preferred in this context are Edelfosine, Miltefosine and Perifosine. In a particularly preferred embodiment, the present invention relates to the use of Miltefosine for the preparation of a pharmaceutical composition for the treatment, prevention and/or amelioration of allergic diseases, in particular acute hyperallergic diseases, like asthma, atopic dermatitis and mastocytosis.

    摘要翻译： 本发明涉及某些内离子（两性离子）磷脂，磷脂酰脂和磷酸酯衍生物在制备用于治疗，预防和/或改善与肥大细胞致敏和/或激活相关的免疫学障碍的药物组合物中的用途 。 在本文中优选的是Edelfosine，Miltefosine和Perifosine。 在特别优选的实施方案中，本发明涉及用于制备用于治疗，预防和/或改善过敏性疾病，特别是急性高过敏性疾病如哮喘，特应性皮炎和肥大细胞增多症的药物组合物的用途。