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1.发明申请USE OF BENZOPHENONE-4 AND ITS SALTS TO QUENCH THE FLUORESCENCE OF DISODIUM PHENYL DIBENZIMIDAZOLE TETRASULFONATE 审中-公开苯并噻吩4及其盐的使用来研究二苯基二苯胺唑酮四氢呋喃的荧光
公开(公告)号：WO2007135197A2
公开(公告)日：2007-11-29
申请号：PCT/EP2007056997
申请日：2007-07-09
Applicant: SYMRISE GMBH & CO KG , JOHNCOCK WILLIAM , CLAUS JUERGEN
Inventor： JOHNCOCK WILLIAM , CLAUS JUERGEN
CPC classification number: A61Q17/04 , A61K8/466 , A61K8/4946
Abstract: The present invention relates to cosmetic preparations for protection of the human skin and human hair against the harmful effects of ultraviolet solar radiation containing the water soluble UVA absorbing substance disodium phenyl dibenzimidazole tetrasulfonate [2,2'-(1,4-Phenylene)bis(1H-benzimidazole-4,6- disulfonic acid, monosodium salt); 1H-Benzimidazole-4,6-Disulfonic Acid, 2,2'- (1,4-Phenylene)Bis-, Disodium Salt] together with Benzophenone-4 (2-Hydroxy- 4-methoxybenzophenone-5-sulfonic acid) and its salts to quench the fluorescence of disodium phenyl dibenzimidazole tetrasulfonate.
Abstract translation: 本发明涉及用于保护人体皮肤和人体毛发免受含有水溶性UVA吸收物质苯基二苯并咪唑四磺酸二钠[2,2' - （1,4-亚苯基）双（ 1H-苯并咪唑-4,6-二磺酸，单钠盐）; 1H-苯并咪唑-4,6-二磺酸，2,2'-（1,4-亚苯基）双 - ，二钠盐]与二苯甲酮-4（2-羟基-4-甲氧基二苯甲酮-5-磺酸）及其 盐以猝灭苯基二苯并咪唑四磺酸二钠的荧光。
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2.发明申请USE OF TROXERUTIN TO QUENCH THE FLUORESCENCE OF DISODIUM PHENYL DIBENZIMIDAZOLE TETRASULFONATE 审中-公开使用三羟甲基纤维素来研究二苯甲基二苯胺唑酮四氢呋喃的荧光
公开(公告)号：WO2007128840A3
公开(公告)日：2008-07-03
申请号：PCT/EP2007058208
申请日：2007-08-07
Applicant: SYMRISE GMBH & CO KG , JOHNCOCK WILLIAM , CLAUS JUERGEN
Inventor： JOHNCOCK WILLIAM , CLAUS JUERGEN
CPC classification number: A61K8/602 , A61K8/4946 , A61K31/00 , A61K2800/434 , A61K2800/522 , A61Q17/04
Abstract: The present invention relates to cosmetic preparations for protection of the human skin and human hair against the harmful effects of ultraviolet solar radiation containing the water soluble UVA absorbing substance disodium phenyl dibenzimidazole tetrasulfonate together with troxerutin to quench the fluorescence of disodium phenyl dibenzimidazole tetrasulfonate, and corresponding methods of manufacturing such preparations and uses of troxerutin and disodium phenyl dibenzimidazole tetrasulfonate.
Abstract translation: 本发明涉及用于保护人体皮肤和人体毛发的抗紫外线辐射的有害影响的化妆品制剂，其含有水溶性UVA吸收剂苯基二苯并咪唑四磺酸二钠与troxerutin二苯醚以猝灭苯基二苯并咪唑四磺酸二钠的荧光，以及相应的 制备此类制剂的方法和曲妥单钠和苯基二苯并咪唑四磺酸二钠的用途。
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3.发明申请STABLE SOLUBLE SALTS OF PHENYLBENZIMIDAZOLE SULFONIC ACID AT PHS AT OR BELOW 7.0 审中-公开苄基苯并咪唑硫酸钠稳定溶解度在下列PHS下7.0
公开(公告)号：WO2007135196A2
公开(公告)日：2007-11-29
申请号：PCT/EP2007/056995
申请日：2007-07-09
Applicant: SYMRISE GMBH & CO. KG , JOHNCOCK, William , CLAUS, Jürgen
Inventor： JOHNCOCK, William , CLAUS, Jürgen
CPC classification number: A61K8/4946 , A61K8/44 , A61Q17/04
Abstract: The invention concerns preparations, particularly cosmetic or pharmaceutical/dermatological preparations, containing phenylbenzimidazole sulfonic acid (i.e. 2-phenylbenzimidazole-5-sulfonic acid) neutralised with basic amino acids such as arginine, lysine, ornithine and histidine so that the pH of the preparation can be at or below 7.0 without incurring crystallisation of the phenylbenzimidazole sulfonic acid.
Abstract translation: 本发明涉及包含用碱性氨基酸如精氨酸，赖氨酸，鸟氨酸和组氨酸中和的苯基苯并咪唑磺酸（即2-苯基苯并咪唑-5-磺酸）的制剂，特别是化妆品或药物/皮肤病学制剂，使得制剂的pH值 处于或低于7.0，而不引起苯基苯并咪唑磺酸的结晶。
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公开(公告)号：WO2003092643A1
公开(公告)日：2003-11-13
申请号：PCT/EP2003/004479
申请日：2003-04-30
Applicant: SYMRISE GMBH & CO. KG , DILK, Erich , KOCH, Oskar , LANGNER, Roland , JOHNCOCK, William
Inventor： DILK, Erich , KOCH, Oskar , LANGNER, Roland , JOHNCOCK, William
IPC: A61K7/42
CPC classification number: A61K8/492 , A61K8/4906 , A61K8/4926 , A61Q17/04 , C07D209/06 , C07D209/08 , C07D209/86 , C07D215/06
Abstract: Kosmetische Zubereitungen, die Acrylnitril-Derivate enthalten, schützen die menschliche Haut und die Haare vor der UV-Strahlung.
Abstract translation: 含有保护免受UV辐射的人的皮肤和头发的丙烯腈衍生物的化妆品制剂。
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5.发明申请
公开(公告)号：WO2006015954A1
公开(公告)日：2006-02-16
申请号：PCT/EP2005/053725
申请日：2005-07-29
Applicant: SYMRISE GMBH & CO. KG , KOCH, Oskar , JOHNCOCK, William
Inventor： KOCH, Oskar , JOHNCOCK, William
IPC: A61K7/42
CPC classification number: C07C255/40 , A61K8/40 , A61Q17/04
Abstract: Beschrieben wird die Verwendung einer Verbindung der Formel (I) als UV-Filter in kosmetischen Formulierungen, insbesondere in Kombination mit UV-Filtern aus der Gruppe der Methoxycinnamat-Derivate und/oder Dibenzoylmethan-Derivate.
Abstract translation: 使用式（I）的化合物的将结合选自甲氧基肉桂酸酯衍生物和/或二苯甲酰甲烷衍生物的描述为在化妆品制剂中的UV过滤剂，特别是用UV滤波器。
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Patent Agency Ranking
公开(公告)号：WO2003084496A1
公开(公告)日：2003-10-16
申请号：PCT/EP2003/002908
申请日：2003-03-20
Applicant: SYMRISE GMBH & CO. KG , LANGNER, Roland , JOHNCOCK, William
Inventor： LANGNER, Roland , JOHNCOCK, William
IPC: A61K7/42
CPC classification number: A61K8/4946 , A61K8/35 , A61K8/37 , A61K2800/52 , A61Q5/00 , A61Q17/04
Abstract: Die vorliegende Erfindung betrifft lichtstabile kosmetische oder dermatologische Lichtschutzzubereitungen mit mindestens einer Lipidphase und mindestens einer wässrigen Phase dadurch gekennzeichnet, dass diese a) mindestens einen auf Dibenzoylmethanderivaten basierenden UV-A Sonnenschutzfilter, b) mindestens einen ein- oder mehrfach sulfonierten und als Salz wasserlöslichen UV-A Sonnenschutzfilter und c) mindestens ein Naphthalindicarbonsäurederivat enthalten, ein Verfahren zur Stabilisierung von Dibenzoylmethanderivaten sowie die Verwendung der Lichtschutzzubereitungen zum Schutz der Haut und der Haare vor UV-Strahlen.
Abstract translation: 本发明涉及包含至少一种脂质相和至少一个水相的光稳定的化妆品或皮肤病学的光保护配制剂，其特征在于它：a）至少一个基于二苯甲酰基甲烷UV-A防晒剂，b）至少一种单 - 或聚磺化和水溶性作为盐UV- 一遮光剂，和c）至少一种Naphthalindicarbonsäurederivat，对二苯甲酰甲烷衍生物的稳定和用于保护免受紫外线伤害的皮肤和毛发上使用防晒准备的过程。
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公开(公告)号：WO0162208A3
公开(公告)日：2001-12-27
申请号：PCT/EP0101563
申请日：2001-02-13
Applicant: HAARMANN & REIMER GMBH , LEY JAKOB PETER , JOHNCOCK WILLIAM , LANGNER ROLAND
Inventor： LEY JAKOB PETER , JOHNCOCK WILLIAM , LANGNER ROLAND
IPC: A61K8/00 , A61K8/49 , A61K8/55 , A61K8/69 , A61Q5/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61K7/48 , A61K7/42
CPC classification number: A61Q19/02 , A61K8/49 , A61K8/4946 , A61K8/55 , A61K8/69 , A61K2800/782 , A61Q5/00 , A61Q17/04 , A61Q19/08
Abstract: The inventive 2-hydrazino-1,3-heteroazoles or salts thereof are, as very good tyrosinase inhibitors, active constituents in topical cosmetic agents, especially in cosmetic or dermatological skin brightening agents.
Abstract translation: 2-肼基-1,3-杂唑或其盐在局部用化妆品中，特别是在化妆品或皮肤用皮肤美白剂中作为非常好的酪氨酸酶抑制剂活性成分是有效的。
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8.发明申请STABLE SOLUBLE SALTS OF PHENYLBENZIMIDAZOLE SULFONIC ACID AT PHS AT OR BELOW 7.0 审中-公开苄基苯并咪唑硫酸钠稳定溶解度在下列PHS下7.0
公开(公告)号：WO2007135196A3
公开(公告)日：2008-05-02
申请号：PCT/EP2007056995
申请日：2007-07-09
Applicant: SYMRISE GMBH & CO KG , JOHNCOCK WILLIAM , CLAUS JUERGEN
Inventor： JOHNCOCK WILLIAM , CLAUS JUERGEN
CPC classification number: A61K8/4946 , A61K8/44 , A61Q17/04
Abstract: The invention concerns preparations, particularly cosmetic or pharmaceutical/dermatological preparations, containing phenylbenzimidazole sulfonic acid (i.e. 2-phenylbenzimidazole-5-sulfonic acid) neutralised with basic amino acids such as arginine, lysine, ornithine and histidine so that the pH of the preparation can be at or below 7.0 without incurring crystallisation of the phenylbenzimidazole sulfonic acid.
Abstract translation: 本发明涉及包含用碱性氨基酸如精氨酸，赖氨酸，鸟氨酸和组氨酸中和的苯基苯并咪唑磺酸（即2-苯基苯并咪唑-5-磺酸）的制剂，特别是化妆品或药物/皮肤病学制剂，使得制剂的pH值 处于或低于7.0，而不引起苯基苯并咪唑磺酸的结晶。
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9.发明申请
公开(公告)号：WO2007135197A3
公开(公告)日：2007-11-29
申请号：PCT/EP2007/056997
申请日：2007-07-09
Applicant: SYMRISE GMBH & CO. KG , JOHNCOCK, William , CLAUS, Jürgen
Inventor： JOHNCOCK, William , CLAUS, Jürgen
Abstract: The present invention relates to cosmetic preparations for protection of the human skin and human hair against the harmful effects of ultraviolet solar radiation containing the water soluble UVA absorbing substance disodium phenyl dibenzimidazole tetrasulfonate [2,2'-(1,4-Phenylene)bis(1H-benzimidazole-4,6- disulfonic acid, monosodium salt); 1H-Benzimidazole-4,6-Disulfonic Acid, 2,2'- (1,4-Phenylene)Bis-, Disodium Salt] together with Benzophenone-4 (2-Hydroxy- 4-methoxybenzophenone-5-sulfonic acid) and its salts to quench the fluorescence of disodium phenyl dibenzimidazole tetrasulfonate.
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10.发明申请3,4-DIHYDROXYBENZYL-SUBSTITUTED CARBONIC ACID DERIVATIVES AND THE USE THEREOF AS ANTIOXIDANTS 审中-公开3,4-二羟基 - 取代二氧化碳衍生物及其抗氧化剂
公开(公告)号：WO0198235A3
公开(公告)日：2002-05-23
申请号：PCT/EP0106568
申请日：2001-06-11
Applicant: HAARMANN & REIMER GMBH , LEY JAKOB PETER , JOHNCOCK WILLIAM , LANGNER ROLAND
Inventor： LEY JAKOB PETER , JOHNCOCK WILLIAM , LANGNER ROLAND
IPC: A01N1/00 , A23L33/10 , A61K8/00 , A61K8/30 , A61K8/33 , A61K8/41 , A61K8/44 , A61K8/46 , A61K8/49 , A61K31/17 , A61K31/27 , A61K31/325 , A61K47/08 , A61K47/16 , A61K47/18 , A61K47/20 , A61Q3/00 , A61Q3/02 , A61Q5/00 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/08 , C07C269/04 , C07C271/06 , C07C271/16 , C07C271/34 , C07C275/10 , C07C279/08 , C07C279/10 , C07C327/00 , C07C333/04 , C07C333/20 , C07C335/00 , C07C335/12 , C09K15/04 , C09K15/20 , C09K15/24 , C09K15/26 , C09K15/28 , A61K7/00
CPC classification number: A61K8/44 , A23L33/10 , A61K8/46 , A61K9/0014 , A61K47/18 , A61K2800/522 , A61Q17/00 , A61Q17/04 , C07C271/16 , C07C271/34 , C07C335/12 , C09K15/20 , C09K15/26
Abstract: The invention relates to 3,4-dihydroxybenzyl-substituted carbonic acid derivatives, to their production, and to their use as antioxidants or free-radical scavengers, especially in cosmetic and pharmaceutical preparations and in foodstuffs and stimulants, to protect cells and tissues from the harmful effects of radicals and reactive oxygen compounds that accelerate aging. The invention further relates to cosmetic and pharmaceutical preparations and to foodstuffs and stimulants that comprises the inventive 3,4-dihydroxybenzyl-substituted carbonic acid derivatives.
Abstract translation: 本发明涉及在化妆品和药物制剂和食品中的3,4-二羟基苄基取代的碳酸衍生物，它们的制备，它们作为抗氧化剂或自由基清除剂的用途，特别用于保护细胞和组织免受自由基老化加速有害影响 和活性氧。 本发明还涉及化妆品和药物制剂以及食品和饮料，其包含这些3,4-二羟基苄基取代的碳酸衍生物。
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