IL-8 RECEPTOR ANTAGONISTS
    1.
    发明申请
    IL-8 RECEPTOR ANTAGONISTS 审中-公开
    IL-8受体拮抗剂

    公开(公告)号:WO1997049680A1

    公开(公告)日:1997-12-31

    申请号:PCT/US1997010903

    申请日:1997-06-24

    CPC classification number: C07C275/34 C07C311/21

    Abstract: This invention relates to the use of phenyl ureas of formulas (I) and (II) in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8). The variables of (I) and (II) are defined herein.

    Abstract translation: 本发明涉及式(I)和(II)的苯基脲在治疗由趋化因子介导的疾病状态白细胞介素-8(IL-8)中的应用。 本文定义(I)和(II)的变量。

    PESTICIDALLY ACTIVE OXIME AND HYDRAZONE DERIVATIVES
    4.
    发明申请
    PESTICIDALLY ACTIVE OXIME AND HYDRAZONE DERIVATIVES 审中-公开
    杀虫活性氧化物和氢氯化物衍生物

    公开(公告)号:WO2016193284A1

    公开(公告)日:2016-12-08

    申请号:PCT/EP2016/062335

    申请日:2016-06-01

    Abstract: The present invention relates to compounds of formula (I) as defined herein, to processes for preparing them, to pesticidal, in particular insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to methods of using them to combat and control pests such as insect, acarine, mollusc and nematode pests.

    Abstract translation: 本发明涉及本文定义的式(I)化合物,其制备方法,包括它们的杀虫剂,特别是杀虫,杀螨,杀软体动物和杀线虫剂的组合物以及使用它们来对抗和控制害虫如昆虫的方法 ,螨虫,软体动物和线虫害虫。

    THE SELECTIVE AND SPECIFIC PREPARATION OF DISCRETE PEG COMPOUNDS

    公开(公告)号:WO2004073620A3

    公开(公告)日:2004-09-02

    申请号:PCT/US2004/004274

    申请日:2004-02-13

    Abstract: Aspects of the present invention are directed to novel methods for making discrete polyethylene compounds selectively and specifically to a predetermined number of ethylene oxide units. Methods which can be used to build up larger dPEG compounds (a) containing a wider range of utility to make useful homoand heterofunctional and branched species, and (b) under reaction configurations and conditions that are milder, more efficient, more diverse in terms of incorporating useful functionality, more controllable, and more versatile then any conventional method reported in the art to date. In addition, the embodiments of the invention allow for processes that allow for significantly improving the ability to purify the intermediates or final product mixtures, making these methods useful for commerial manufacturing dPEGs. Protecting groups and functional groups can be designed to make purification at large scale a practical reality. The novel dPEG products form the compositional and material basis for making other novel compounds of valuable application in the fields of diagnostics and therapeutics, amongst others.

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