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    FUNCTIONAL OPTICAL COHERENT IMAGING
    1.
    发明申请
    FUNCTIONAL OPTICAL COHERENT IMAGING 审中-公开
    功能光学相干成像

    公开(公告)号：WO2010004365A1

    公开(公告)日：2010-01-14

    申请号：PCT/IB2008/052787

    申请日：2008-07-10

    Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) ,  LASSER, Theo ,  VAN DE VILLE, Dimitri ,  MARTIN-WILLIAMS, Erica ,  LEUTENEGGER, Marcel ,  MAERKI, Iwan ,  FRIEDRICH, Michael ,  VILLIGER, Martin

    Inventor： LASSER, Theo ,  VAN DE VILLE, Dimitri ,  MARTIN-WILLIAMS, Erica ,  LEUTENEGGER, Marcel ,  MAERKI, Iwan ,  FRIEDRICH, Michael ,  VILLIGER, Martin

    IPC: A61B5/00 ,  A61B5/026 ,  A61B3/12

    CPC classification number: A61B5/0066 ,  A61B3/102 ,  A61B3/1233 ,  A61B5/0048 ,  A61B5/0059 ,  A61B5/02028 ,  A61B5/413 ,  A61B5/7203 ,  A61B5/726 ,  A61B5/7278 ,  A61B5/742

    Abstract: The present invention relates to a functional optical coherent imaging (fOCI) platform comprising at least one active camera unit (ACU) comprising a coherent and/or a partially coherent light source, and means for spectral filtering and imaging a selected body area of interest; an image processing unit (IPU) for pre-processing data received from an ACU; at least one stimulation unit (STU) transmitting a stimulation to a subject; at least one body function reference measurement unit (BFMU); a central clock and processing unit (CCU), with interconnections to the ACU, the IPU, the STU, for collecting pre-processed data from the IPU, stimuli from the STU body function reference data from the BFMU in a synchronized manner; a post-processing unit (statistical analysis unit, SAU); and an operator interface (HOI). Further the invention relates to a process for acquiring stimuli activated subject data comprising the steps of aligning a body function unit at a subject and monitoring pre-selected body function; selecting a stimulus or stimuli; imaging a body area of interest; exerting one or a series of stimuli on the subject; imaging the body area of interest synchronous with said stimuli and the preselected body functions; and transferring said synchronized image, stimuli and body function data to a statistical analysis unit (SAU) and performing calculations to generate results pertaining to body functions.

    Abstract translation: 功能性光学相干成像（fOCI）平台本发明涉及包括至少一个包括相干和/或部分相干光源的有源相机单元（ACU）的功能性光学相干成像（fOCI）平台，以及用于对感兴趣的所选择的身体区域进行频谱滤波和成像的装置; 用于预处理从ACU接收的数据的图像处理单元（IPU）; 向受试者传送刺激的至少一个刺激单元（STU）; 至少一个身体功能参考测量单元（BFMU）; 中央时钟和处理单元（CCU），与ACU，IPU，STU的互连，用于从IPU收集预处理的数据，以同步方式从BFMU的STU主体功能参考数据的刺激; 后处理单位（统计分析单位，SAU）; 和操作界面（HOI）。 此外，本发明涉及一种用于获取刺激激活的受试者数据的方法，包括以下步骤：对准受试者的身体功能单元并监测预先选择的身体功能; 选择刺激或刺激; 成像感兴趣的身体区域; 在该主题上施加一个或一系列刺激; 对与所述刺激同步的感兴趣的身体区域和预选的身体功能进行成像; 以及将所述同步图像，刺激和身体功能数据传送到统计分析单元（SAU）并执行计算以产生与身体功能有关的结果。

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