公开(公告)号：WO2004079002A8

公开(公告)日：2005-12-01

申请号：PCT/CN0300328

申请日：2003-05-06

Applicant: UNIV TSINGHUA ,  CAPITAL BIOCHIP CO LTD ,  TAO SHENGE ,  CHENG JING ,  MAX XUMEI ,  ZHOU YUXIANG

Inventor： TAO SHENGE ,  CHENG JING ,  MAX XUMEI ,  ZHANG QIONG ,  ZHOU YUXIANG

IPC: B01L3/00 ,  B01L7/00 ,  C12Q1/68 ,  C40B40/06 ,  C40B60/14

CPC classification number: B01L3/508 ,  B01J2219/00385 ,  B01J2219/00527 ,  B01J2219/00608 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00626 ,  B01J2219/0063 ,  B01J2219/00722 ,  B01L7/52 ,  B01L2300/0636 ,  B01L2300/0822 ,  B01L2300/163 ,  C12Q1/6837 ,  C40B40/06 ,  C40B60/14 ,  C12Q2547/101 ,  C12Q2531/131

Abstract: This invention relates generally to the field of nucleic acid detection. In particular, the invention provides a lab-on-chip system for analyzing a nucleic acid, which system comprises, inter alia, controllably closed space, and a target nucleic acid can be prepared and/or amplified, and hybridized to a nucleic acid probe, and the hybridization signal can be acquired if desirable, in the controllably closed space without any material exchange between the controllably closed space and the outside environment. Methods for analyzing a nucleic acid using the lab-on-chip system is also provided.

Abstract translation: 本发明一般涉及核酸检测领域。 特别地，本发明提供了用于分析核酸的片上实验室系统，该系统尤其包括可控制的封闭空间，并且靶核酸可以制备和/或扩增，并与核酸探针杂交 ，并且如果需要，可以在可控制的封闭空间中获取杂交信号，而在可控制的封闭空间和外部环境之间没有任何物质交换。 还提供了使用片上实验室系统分析核酸的方法。

公开(公告)号：WO2004079002A1

公开(公告)日：2004-09-16

申请号：PCT/CN2003/000328

申请日：2003-05-06

Applicant: TSINGHUA UNIVERSITY ,  CAPITAL BIOCHIP COMPANY, LTD. ,  ZHANG, Qiong ,  TAO, Shenge ,  CHENG, Jing ,  MAX, Xumei ,  ZHOU, Yuxiang

Inventor： TAO, Shenge ,  CHENG, Jing ,  MAX, Xumei ,  ZHOU, Yuxiang

IPC: C12Q1/68

CPC classification number: B01L3/508 ,  B01J2219/00385 ,  B01J2219/00527 ,  B01J2219/00608 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00626 ,  B01J2219/0063 ,  B01J2219/00722 ,  B01L7/52 ,  B01L2300/0636 ,  B01L2300/0822 ,  B01L2300/163 ,  C12Q1/6837 ,  C40B40/06 ,  C40B60/14 ,  C12Q2547/101 ,  C12Q2531/131

Abstract: This invention relates generally to the field of nucleic acid detection. In particular, the invention provides a lab-on-chip system for analyzing a nucleic acid, which system comprises, inter alia , controllably closed space, and a target nucleic acid can be prepared and/or amplified, and hybridized to a nucleic acid probe, and the hybridization signal can be acquired if desirable, in the controllably closed space without any material exchange between the controllably closed space and the outside environment. Methods for analyzing a nucleic acid using the lab-on-chip system is also provided.

Abstract translation: 本发明一般涉及核酸检测领域。 特别地，本发明提供了用于分析核酸的片上实验室系统，该系统尤其包括可控制的封闭空间，并且靶核酸可以制备和/或扩增，并与核酸探针杂交 ，并且如果需要，可以在可控制的封闭空间中获取杂交信号，而在可控制的封闭空间和外部环境之间没有任何物质交换。 还提供了使用片上实验室系统分析核酸的方法。