公开(公告)号：WO2010085793A2

公开(公告)日：2010-07-29

申请号：PCT/US2010/022081

申请日：2010-01-26

Applicant: SYNTHES USA, LLC ,  SYNTHES GMBH ,  ADAMS, Ray ,  BANKS, David, T. ,  BERTAGNOLI, Rudolf ,  HELFER, Joel ,  LARSEN, Scott ,  LAURENCE, Lawton ,  LEHMAN, Adam ,  MANOS, Jamie ,  MATA, Vinny ,  MESSERLI, Dominique ,  OVERES, Tom ,  SINGHATAT, Wamis ,  TALBOT, James ,  UNDERHILL, Ken ,  VENNARD, Daniel

Inventor： ADAMS, Ray ,  BANKS, David, T. ,  BERTAGNOLI, Rudolf ,  HELFER, Joel ,  LARSEN, Scott ,  LAURENCE, Lawton ,  LEHMAN, Adam ,  MANOS, Jamie ,  MATA, Vinny ,  MESSERLI, Dominique ,  OVERES, Tom ,  SINGHATAT, Wamis ,  TALBOT, James ,  UNDERHILL, Ken ,  VENNARD, Daniel

IPC: A61B17/04 ,  A61B17/00 ,  A61B17/06

CPC classification number: A61B17/0482 ,  A61B17/0469 ,  A61B17/06066 ,  A61B17/0625 ,  A61B2017/00477 ,  A61B2017/00867 ,  A61B2017/0496

Abstract: A bi-directional suture passing instrument configured to approach soft tissues perpendicularly, enables safer and more efficient surgical repairs and minimally invasive techniques to be employed, useful in areas such as annulus repair, meniscal repair, shoulder arthroscopy, hernia repair, laproscopic repair, and wound closure.

Abstract translation: 构造成垂直接近软组织的双向缝合线通过仪器使得能够采用更安全和更有效的外科手术修复和微创技术，在诸如环形修复，半月板修复，肩关节镜检查，疝修补，腹腔镜修复和 伤口闭合。

公开(公告)号：WO2009006432A2

公开(公告)日：2009-01-08

申请号：PCT/US2008/068836

申请日：2008-06-30

Applicant: SYNTHES (U.S.A.) ,  SYNTHES GMBH ,  COMPTON, Curtis ,  CHIEN, Dennis ,  DELURIO, Robert ,  MESSERLI, Dominique

Inventor： COMPTON, Curtis ,  CHIEN, Dennis ,  DELURIO, Robert ,  MESSERLI, Dominique

IPC: A61B17/88 ,  A61B17/70

CPC classification number: A61F2/442 ,  A61B17/7094 ,  A61F2/28 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/30281 ,  A61F2002/30289 ,  A61F2002/30387 ,  A61F2002/30403 ,  A61F2002/30471 ,  A61F2002/30472 ,  A61F2002/30476 ,  A61F2002/30504 ,  A61F2002/30594 ,  A61F2002/4415 ,  A61F2002/444 ,  A61F2002/4627 ,  A61F2220/0025 ,  A61F2220/0041 ,  A61F2220/0091 ,  A61F2230/0086 ,  A61F2230/0091 ,  A61F2310/00359

Abstract: A flexible chain implant for insertion into an interior volume of a vertebral body. The implant may be implanted in an insertion position for sliding through a cannula and is flexible for packing into the interior volume in an implanted configuration. The implant randomly separates in the implanted configuration. The implant includes a top member and a bottom member, wherein the top and bottom members are coupled to one another at a coupled portion. The top and bottom members preferably each include an inner surface such that the inner surfaces include a plurality of alternating projections and recesses so that the projections are received within the recesses in an insertion position. Alternatively, the implant may include a plurality of substantially non- flexible bodies and a plurality of substantially flexible links interconnecting the bodies. The non-flexible bodies include a plurality of facets and/or abutment surfaces.

Abstract translation: 用于插入椎体内部体积的柔性链植入物。 植入物可以植入插入位置以滑动通过插管，并且是柔性的，以植入构型包装到内部容积中。 植入物在植入构型中随机分离。 植入物包括顶部构件和底部构件，其中顶部构件和底部构件在联接部分处彼此联接。 顶部和底部构件优选地各自包括内表面，使得内表面包括多个交替的突起和凹部，使得突起在插入位置中容纳在凹部内。 或者，植入物可以包括多个基本上非弹性的主体和互连主体的多个基本上柔性的连杆。 非柔性体包括多个面和/或邻接表面。

公开(公告)号：WO2007028046A2

公开(公告)日：2007-03-08

申请号：PCT/US2006034270

申请日：2006-08-31

Applicant: HFSC CO ,  SYNTHES GMBH ,  BANKOSKI BRIAN R ,  EVANS DAVID E ,  MESSERLI DOMINIQUE

Inventor： BANKOSKI BRIAN R ,  EVANS DAVID E ,  MESSERLI DOMINIQUE

IPC: A61F2/00 ,  B65D25/08 ,  B65D81/32

CPC classification number: B65D77/2024 ,  A61F2/0095 ,  B65D25/082 ,  B65D25/085 ,  B65D81/32 ,  B65D81/3238

Abstract: Packages for the rehydration of implants are described, wherein the package may contain a first chamber containing a rehydration fluid, a second chamber containing an implant, and a barrier configured to be affected without compromising the sterility of the package. The rehydration fluid may engage and rehydrate the implant after the barrier is ruptured. Methods of use are also described.

Abstract translation: 描述了用于植入物再水合的包装，其中包装可以包含含有补液的第一室，包含植入物的第二室和被构造成受影响而不影响包装的无菌性的屏障。 补水液体可能会在屏障破裂后接合并再植入植入物。 还描述了使用方法。

公开(公告)号：WO0170136A9

公开(公告)日：2003-04-03

申请号：PCT/US0109270

申请日：2001-03-22

Applicant: SYNTHES USA ,  SYNTHES AG ,  BOYER MICHAEL L II ,  PAUL DAVID C ,  HIGGINS THOMAS B ,  ANGELUCCI CHRISTOPHER M ,  MESSERLI DOMINIQUE D ,  KOBAYASHI KENNETH I

Inventor： BOYER MICHAEL L II ,  PAUL DAVID C ,  HIGGINS THOMAS B ,  ANGELUCCI CHRISTOPHER M ,  MESSERLI DOMINIQUE D ,  KOBAYASHI KENNETH I

IPC: A61B17/88 ,  A61F2/00 ,  A61F2/02 ,  A61F2/28 ,  A61F2/30 ,  A61F2/44 ,  A61F2/46 ,  B29C33/26 ,  B29C43/00

CPC classification number: A61F2/30744 ,  A61B17/8875 ,  A61F2/28 ,  A61F2/30724 ,  A61F2/3094 ,  A61F2/30942 ,  A61F2/30965 ,  A61F2/44 ,  A61F2/442 ,  A61F2/4455 ,  A61F2/4465 ,  A61F2/4611 ,  A61F2/4644 ,  A61F2002/2817 ,  A61F2002/2825 ,  A61F2002/2835 ,  A61F2002/2839 ,  A61F2002/2853 ,  A61F2002/30011 ,  A61F2002/30057 ,  A61F2002/30062 ,  A61F2002/30075 ,  A61F2002/30112 ,  A61F2002/30115 ,  A61F2002/30126 ,  A61F2002/30131 ,  A61F2002/30133 ,  A61F2002/30138 ,  A61F2002/30148 ,  A61F2002/30151 ,  A61F2002/30153 ,  A61F2002/30154 ,  A61F2002/30158 ,  A61F2002/30166 ,  A61F2002/30168 ,  A61F2002/30179 ,  A61F2002/302 ,  A61F2002/3021 ,  A61F2002/30212 ,  A61F2002/30224 ,  A61F2002/30225 ,  A61F2002/30228 ,  A61F2002/3023 ,  A61F2002/30232 ,  A61F2002/30233 ,  A61F2002/30235 ,  A61F2002/30237 ,  A61F2002/30238 ,  A61F2002/3024 ,  A61F2002/30261 ,  A61F2002/3028 ,  A61F2002/30299 ,  A61F2002/30322 ,  A61F2002/30324 ,  A61F2002/30327 ,  A61F2002/30329 ,  A61F2002/30331 ,  A61F2002/30332 ,  A61F2002/30354 ,  A61F2002/30367 ,  A61F2002/30377 ,  A61F2002/3038 ,  A61F2002/30382 ,  A61F2002/30383 ,  A61F2002/30387 ,  A61F2002/30405 ,  A61F2002/30411 ,  A61F2002/30426 ,  A61F2002/30433 ,  A61F2002/30434 ,  A61F2002/30436 ,  A61F2002/30441 ,  A61F2002/30443 ,  A61F2002/30448 ,  A61F2002/30459 ,  A61F2002/30462 ,  A61F2002/30472 ,  A61F2002/30477 ,  A61F2002/30481 ,  A61F2002/30484 ,  A61F2002/30487 ,  A61F2002/30492 ,  A61F2002/30494 ,  A61F2002/305 ,  A61F2002/30502 ,  A61F2002/30507 ,  A61F2002/3051 ,  A61F2002/30515 ,  A61F2002/30538 ,  A61F2002/3054 ,  A61F2002/30543 ,  A61F2002/3055 ,  A61F2002/30565 ,  A61F2002/30579 ,  A61F2002/30593 ,  A61F2002/30594 ,  A61F2002/30596 ,  A61F2002/30599 ,  A61F2002/30604 ,  A61F2002/30616 ,  A61F2002/30617 ,  A61F2002/30714 ,  A61F2002/30733 ,  A61F2002/30746 ,  A61F2002/30772 ,  A61F2002/30782 ,  A61F2002/30785 ,  A61F2002/30787 ,  A61F2002/30789 ,  A61F2002/3079 ,  A61F2002/30797 ,  A61F2002/30805 ,  A61F2002/30808 ,  A61F2002/3081 ,  A61F2002/30812 ,  A61F2002/3082 ,  A61F2002/30822 ,  A61F2002/30828 ,  A61F2002/30831 ,  A61F2002/30841 ,  A61F2002/30843 ,  A61F2002/3085 ,  A61F2002/30879 ,  A61F2002/30892 ,  A61F2002/30894 ,  A61F2002/30904 ,  A61F2002/30909 ,  A61F2002/30957 ,  A61F2002/30971 ,  A61F2002/30975 ,  A61F2002/4475 ,  A61F2002/4635 ,  A61F2002/4638 ,  A61F2002/4649 ,  A61F2210/0004 ,  A61F2210/0061 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2220/0041 ,  A61F2220/005 ,  A61F2220/0066 ,  A61F2220/0075 ,  A61F2230/0004 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/0013 ,  A61F2230/0015 ,  A61F2230/0017 ,  A61F2230/0019 ,  A61F2230/0021 ,  A61F2230/0026 ,  A61F2230/0028 ,  A61F2230/0043 ,  A61F2230/0058 ,  A61F2230/0063 ,  A61F2230/0065 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0082 ,  A61F2230/0093 ,  A61F2250/0006 ,  A61F2250/0023 ,  A61F2250/0026 ,  A61F2250/0036 ,  A61F2250/0039 ,  A61F2250/0063 ,  A61F2250/0089 ,  A61F2250/0097 ,  A61F2310/00011 ,  A61F2310/00023 ,  A61F2310/00179 ,  A61F2310/00293 ,  A61F2310/00353 ,  B29C33/26 ,  B29C43/006 ,  B29L2031/3041

Abstract: The present invention relates to plugs (10,560) for filling vacancies in bone tissue. The plugs (10,560) include a body (12,566) and at least one endcap (14,16,562,564) that are coupled together and may be formed from bone. The body (12,566) of the plug (10,560) may be a sleeve (202,566), and the plug (10,560) may further include an insert (572) configured and dimensioned to be received in the sleeve (202,566).

Abstract translation: 本发明涉及用于填充骨组织中的空位的塞子（10,560）。 塞子（10,560）包括主体（12,566）和至少一个端盖（14,16,562,564），其连接在一起并且可以由骨形成。 插头（10,560）的主体（12,566）可以是套筒（202,566），并且插头（10,560）还可以包括被配置和尺寸设置成被接收在套筒（202,566）中的插入件（572）。

公开(公告)号：WO2010085793A3

公开(公告)日：2010-09-10

申请号：PCT/US2010022081

申请日：2010-01-26

Applicant: SYNTHES USA LLC ,  SYNTHES GMBH ,  ADAMS RAY ,  BANKS DAVID T ,  BERTAGNOLI RUDOLF ,  HELFER JOEL ,  LARSEN SCOTT ,  LAURENCE LAWTON ,  LEHMAN ADAM ,  MANOS JAMIE ,  MATA VINNY ,  MESSERLI DOMINIQUE ,  OVERES TOM ,  SINGHATAT WAMIS ,  TALBOT JAMES ,  UNDERHILL KEN ,  VENNARD DANIEL

Inventor： ADAMS RAY ,  BANKS DAVID T ,  BERTAGNOLI RUDOLF ,  HELFER JOEL ,  LARSEN SCOTT ,  LAURENCE LAWTON ,  LEHMAN ADAM ,  MANOS JAMIE ,  MATA VINNY ,  MESSERLI DOMINIQUE ,  OVERES TOM ,  SINGHATAT WAMIS ,  TALBOT JAMES ,  UNDERHILL KEN ,  VENNARD DANIEL

IPC: A61B17/04 ,  A61B17/00 ,  A61B17/06

CPC classification number: A61B17/0482 ,  A61B17/0469 ,  A61B17/06066 ,  A61B17/0625 ,  A61B2017/00477 ,  A61B2017/00867 ,  A61B2017/0496

Abstract: A bi-directional suture passing instrument configured to approach soft tissues perpendicularly, enables safer and more efficient surgical repairs and minimally invasive techniques to be employed, useful in areas such as annulus repair, meniscal repair, shoulder arthroscopy, hernia repair, laproscopic repair, and wound closure.

Abstract translation: 被配置为垂直接近软组织的双向缝合线穿过器械使得能够使用更安全和更有效的手术修复和微创技术，可用于诸如环状修复，半月板修复，肩关节镜检查，疝修复，腹腔镜修复以及 伤口闭合。

公开(公告)号：WO2007098288A2

公开(公告)日：2007-08-30

申请号：PCT/US2007/005098

申请日：2007-02-27

Applicant: SYNTHES (U.S.A.) ,  SYNTHES GMBH ,  MESSERLI, Dominique ,  WALSH, Ryan, T. ,  RANDALL, Brandon, L. ,  EVANS, David, E. ,  MEYERS, Jackie ,  KOCH, David ,  HUNZIKER, Markus

Inventor： MESSERLI, Dominique ,  WALSH, Ryan, T. ,  RANDALL, Brandon, L. ,  EVANS, David, E. ,  MEYERS, Jackie ,  KOCH, David ,  HUNZIKER, Markus

IPC: A61F2/44

CPC classification number: A61F2/447 ,  A61B17/86 ,  A61F2/28 ,  A61F2/442 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/2835 ,  A61F2002/30004 ,  A61F2002/30187 ,  A61F2002/30387 ,  A61F2002/30507 ,  A61F2002/30578 ,  A61F2002/30579 ,  A61F2002/30604 ,  A61F2002/30784 ,  A61F2002/30843 ,  A61F2002/30845 ,  A61F2002/30884 ,  A61F2002/30904 ,  A61F2002/4475 ,  A61F2220/0025 ,  A61F2250/0014 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00179 ,  A61F2310/00359

Abstract: An intervertebral spacer implant is provided with a retention mechanism to help alleviate expulsion and movement of the implant when placed in the spine while providing an implant that is easier to insert in the spine. In one embodiment the retention mechanism comprises a keel on at least one of the inferior or superior faces of the spacer implant preferably extending in an anterior-posterior direction. In another embodiment the implant comprises a spacer and a plate, the plate comprising a supplemental or alternative retention mechanism. In one embodiment the retention mechanism comprises one or more holes in the anterior end of the plate that are directed toward the superior, inferior or both endplates of adjacent vertebrae. In yet another embodiment, the retention mechanism comprises one or more blades that are in a first position when inserted and are preferably rotated to a second position that engages the superior and inferior vertebrae.

Abstract translation: 椎间间隔植入物设置有保持机构，以在放置在脊柱中时有助于减轻植入物的排出和移动，同时提供更容易插入到脊柱中的植入物。 在一个实施例中，保持机构包括在间隔件植入件的下表面或上表面中的至少一个上的龙骨，优选地在前后方向上延伸。 在另一个实施例中，植入物包括间隔物和板，该板包括补充或替代的保持机构。 在一个实施例中，保持机构包括板的前端中的一个或多个孔，其指向相邻椎骨的上，下或两个端板。 在另一个实施例中，保持机构包括一个或多个在插入时处于第一位置的叶片，并且优选地旋转到与上下椎骨接合的第二位置。

公开(公告)号：WO2007076049A2

公开(公告)日：2007-07-05

申请号：PCT/US2006049105

申请日：2006-12-20

Applicant: SYNTHES USA ,  SYNTHES GMBH ,  MESSERLI DOMINIQUE

Inventor： MESSERLI DOMINIQUE

IPC: A61B17/56

CPC classification number: A61F2/441 ,  A61B17/68 ,  A61B17/7094 ,  A61B2017/00004 ,  A61B2017/00526 ,  A61F2/3609 ,  A61F2/44 ,  A61F2/442 ,  A61F2/4455 ,  A61F2/4465 ,  A61F2/447 ,  A61F2002/4415 ,  A61F2002/4475 ,  A61F2210/0004 ,  A61F2250/0003

Abstract: Implants and methods for augmentation, preferably by minimally invasive procedures and means, of body tissue, including in some embodiments repositioning of body tissue, for example, bone and, preferably vertebrae are described. The implant may comprise one or more chain linked bodies inserted into the interior of body tissue. As linked bodies are inserted into body tissue, they may fill a central portion thereof and for example in bone can push against the inner sides of the cortical exterior surface layer, for example the end plates of a vertebral body, thereby providing structural support and tending to restore the body tissue to its original or desired treatment height. A bone cement or other filler can be added to further augment and stabilize the body tissue. The preferred implant comprises a single flexible monolithic chain formed of allograft cortical bone having a plurality of substantially non-flexible bodies connected by substantially flexible links.

Abstract translation: 描述了用于增加身体组织的植入物和方法，优选通过微创手术和手段，包括在一些实施例中，重新定位身体组织，例如骨和优选椎骨。 植入物可以包括插入到身体组织内部的一个或多个链接体。 当连接体插入体组织中时，它们可以填充其中心部分，例如在骨骼中可以推靠在皮质外表面层的内侧，例如椎体的端板，由此提供结构支撑和抚平 将身体组织恢复到其原始或期望的治疗高度。 可以加入骨水泥或其他填充物以进一步增加和稳定身体组织。 优选的植入物包括由同种异体移植皮质骨形成的单个柔性整体链，其具有通过基本上柔性的连接连接的多个基本上非柔性的主体。

公开(公告)号：WO2005097004A3

公开(公告)日：2007-04-26

申请号：PCT/US2005010255

申请日：2005-03-28

Applicant: SYNTHES USA ,  RANDALL BRANDON L ,  GOODWIN ROGER D ,  MESSERLI DOMINIQUE ,  MYER JACQUELINE ,  DELURIO ROBERT J ,  BOYER MICHAEL L II ,  ANGELUCCI CHRISTOPHER M

Inventor： RANDALL BRANDON L ,  GOODWIN ROGER D ,  MESSERLI DOMINIQUE ,  MYER JACQUELINE ,  DELURIO ROBERT J ,  BOYER MICHAEL L II ,  ANGELUCCI CHRISTOPHER M

IPC: A61F2/28 ,  A61B17/88 ,  A61B17/92 ,  A61F2/00 ,  A61F2/30 ,  A61F2/44 ,  A61F2/46

CPC classification number: A61F2/44 ,  A61F2/28 ,  A61F2/3094 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/2835 ,  A61F2002/30057 ,  A61F2002/30266 ,  A61F2002/30383 ,  A61F2002/30387 ,  A61F2002/30492 ,  A61F2002/30507 ,  A61F2002/30571 ,  A61F2002/30604 ,  A61F2002/30617 ,  A61F2002/30782 ,  A61F2002/30795 ,  A61F2002/3082 ,  A61F2002/30843 ,  A61F2002/30904 ,  A61F2002/4622 ,  A61F2002/4628 ,  A61F2002/4629 ,  A61F2220/0025 ,  A61F2230/0082 ,  A61F2250/0097 ,  A61F2310/00359

Abstract: An allogenic implant for use in intervertebral fusion is formed from one or more two pieces. The pieces are made from bone, and are joined together to form an implant having sufficient strength and stability to maintain a desired distance between first and second vertebrae in a spinal fusion procedure. The implant pieces may be formed of cortical bone and connected by dovetail joints, and at least one cortical bone pin may be provided to lock the pieces together and to add strength to the implant. Teeth are formed on the vertebra engaging surfaces of the implant prevent short-term slippage of the implant.

Abstract translation: 用于椎间融合的同种异体植入物由一个或多个两片形成。 这些片由骨制成，并且连接在一起以形成具有足够的强度和稳定性的植入物，以在脊柱融合程序中保持第一和第二椎骨之间的期望距离。 植入物片可以由皮质骨形成并且通​​过燕尾关节连接，并且可以提供至少一个皮质骨针将锁定在一起并增加植入物的强度。 牙齿形成在植入物的椎骨接合表面上，防止植入物的短期滑动。

公开(公告)号：WO2007028046A3

公开(公告)日：2007-03-08

申请号：PCT/US2006/034270

申请日：2006-08-31

Applicant: HFSC COMPANY ,  SYNTHES GMBH ,  BANKOSKI, Brian, R. ,  EVANS, David, E. ,  MESSERLI, Dominique

Inventor： BANKOSKI, Brian, R. ,  EVANS, David, E. ,  MESSERLI, Dominique

IPC: A61F2/00 ,  B65D25/08 ,  B65D81/32 ,  B65D77/20

Abstract: Packages for the rehydration of implants are described, wherein the package (10) may contain a first chamber (20) containing a rehydration fluid (24) , a second chamber (22) containing an implant (26) , and a barrier (30) configured to be affected without compromising the sterility of the package. The rehydration fluid (24) may engage and rehydrate the implant (26) after the barrier (30) is ruptured. Methods of use are also described.

公开(公告)号：WO2006116306A3

公开(公告)日：2006-11-02

申请号：PCT/US2006/015465

申请日：2006-04-24

Applicant: HFSC COMPANY ,  SYNTHES GMBH ,  RANDALL, Brandon ,  KOBAYASHI, Kenneth ,  MESSERLI, Dominique

Inventor： RANDALL, Brandon ,  KOBAYASHI, Kenneth ,  MESSERLI, Dominique

IPC: A61F2/44

Abstract: The present application is directed to a spinal implant (10) , preferably a bioresorbable spinal implant, for insertion between vertebrae bodies. The implant preferably includes an anterior surface (12) , a posterior surface (14) , first and second lateral surfaces (16,18) extending therebetween, a superior surface (20) for engaging one of the vertebrae bodies, an inferior surface (22) for engaging the other vertebrae body, and a central bore (30) which extends from the superior surface to the inferior surface. The central bore preferably has a generally lobe- shaped footprint. The anterior surface of the implant preferably includes a pair of vertical channels (40) sized and configured to engage an insertion instrument and the superior surface preferably has a convexly curved surface extending substantially from the anterior surface to the posterior surface while the inferior surface preferably has a substantially constant taper extending from the anterior surface to the posterior surface.