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    NEW COSMETIC COMPOSITIONS COMPRISING AT LEAST ONE PEPTIDE WITH AT LEAST ONE IMMOBILIZED AROMATIC CYCLE
    1.
    发明申请
    NEW COSMETIC COMPOSITIONS COMPRISING AT LEAST ONE PEPTIDE WITH AT LEAST ONE IMMOBILIZED AROMATIC CYCLE 审中-公开
    至少一个固定化的芳香周期的新型化妆品组合物

    公开(公告)号：WO2007129270A2

    公开(公告)日：2007-11-15

    申请号：PCT/IB2007/051677

    申请日：2007-05-04

    Applicant: SEDERMA ,  LINTNER, Karl ,  PESCHARD, Olivier

    Inventor： LINTNER, Karl ,  PESCHARD, Olivier

    IPC: A61K8/00 ,  A61K38/00

    CPC classification number: A61K8/64 ,  A61K38/08 ,  A61Q1/02 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08

    Abstract: Topical cosmetic use as a whitening active ingredient of at least one peptide, comprising at least one immobilized aromatic cycle and having the general formula (I): A-(Xa)m-Xc-(Xb)n-B. The invention also discloses a cosmetic composition comprising at least said peptide and a method of decreasing skin pigmentation, whitening or lightening human skin, comprising a topical application of said composition.

    Abstract translation: 作为至少一种肽的增白活性成分的局部美容用途，包含至少一个固定化的芳族环并具有通式（I）：A-（Xa）m -Xc-（Xb）n-B。 本发明还公开了包含至少所述肽的化妆品组合物和减少皮肤色素沉着，增白或增亮人皮肤的方法，其包括所述组合物的局部施用。

    COMPOUNDS FOR COSMETIC AND DERMOPHARMACEUTICAL
    2.
    发明申请
    COMPOUNDS FOR COSMETIC AND DERMOPHARMACEUTICAL 审中-公开
    化妆品和化妆品的化合物

    公开(公告)号：WO2010082177A3

    公开(公告)日：2012-01-19

    申请号：PCT/IB2010050192

    申请日：2010-01-15

    Applicant: SEDERMA SA ,  FOURNIAL ARNAUD ,  MONDON PHILIPPE ,  PESCHARD OLIVIER

    Inventor： FOURNIAL ARNAUD ,  MONDON PHILIPPE ,  PESCHARD OLIVIER

    IPC: C07K5/08 ,  A61K8/64 ,  A61K8/97 ,  A61K38/06 ,  A61P17/00 ,  A61Q19/08 ,  C07K5/06 ,  C07K5/10

    CPC classification number: C07K5/081 ,  A61K8/64 ,  A61K8/97 ,  A61Q1/06 ,  A61Q5/006 ,  A61Q7/00 ,  A61Q19/00 ,  A61Q19/001 ,  A61Q19/06 ,  A61Q19/08 ,  C07K5/0606 ,  C07K5/06086 ,  C07K5/0815 ,  C07K5/1008 ,  C07K5/1013 ,  C07K5/1019

    Abstract: The present invention relates to the cosmetic and dermopharmaceutical fields. It concerns compounds having the following formula II : R1-(AA)n-R2 (SEQ ID NO 1 to SEQ ID NO 7) wherein: AA is selected from an amino acid, an amino acid derivative and an amino acid analogue; n=1 to 10, when n = 2, the AA can be different and the bonds being of peptidic or peptoidic type; R1 is either an H or a lipophilic chain, R2 is either an OH or a lipophilic chain, characterised in that the AA or when n>l at least one of the AA comprise at least one sulfur atom in an oxygenated form, preferably a dioxygenated form. More preferably, AA is a dioxygenated SO2 methionine. Results on the activity of the compounds are obtained and on the general state of the skin and its appendages, especially via the stimulation of extracellular matrix components.

    Abstract translation: 本发明涉及化妆品和皮肤药物领域。 它涉及具有下式II的化合物：R1-（AA）n-R2（SEQ ID NO：1至SEQ ID NO：7）其中：AA选自氨基酸，氨基酸衍生物和氨基酸类似物; n = 1至10，当n = 2时，AA可以不同，并且键是肽或类肽类型; R1是H或亲脂性链，R2是OH或亲脂性链，其特征在于AA或当n≥1时，至少一个AA包含氧化形式的至少一个硫原子，优选为双加氧 形成。 更优选地，AA是二氧化的SO 2甲硫氨酸。 获得化合物活性的结果，以及皮肤及其附属物的一般状态，特别是通过刺激细胞外基质组分。

    COMPOSITIONS CONTAINING KXK TYPE PEPTIDES
    4.
    发明申请
    COMPOSITIONS CONTAINING KXK TYPE PEPTIDES 审中-公开
    含有KXK型胶原蛋白的组合物

    公开(公告)号：WO2010082176A3

    公开(公告)日：2010-10-07

    申请号：PCT/IB2010050191

    申请日：2010-01-15

    Applicant: SEDERMA SA ,  FOURNIAL ARNAUD ,  MONDON PHILIPPE ,  PESCHARD OLIVIER

    Inventor： FOURNIAL ARNAUD ,  MONDON PHILIPPE ,  PESCHARD OLIVIER

    IPC: C07K5/08 ,  A61K8/64 ,  A61K38/06 ,  A61P17/00

    CPC classification number: C07K5/0815 ,  A61K8/64 ,  A61K38/06 ,  A61Q1/06 ,  A61Q5/006 ,  A61Q5/02 ,  A61Q7/00 ,  A61Q19/00 ,  A61Q19/001 ,  A61Q19/06 ,  A61Q19/08

    Abstract: The invention proposes a cosmetic composition comprising: -a peptide of formula R1 -K-AA-K-R2, in which K represents a lysine and AA an amino acid incorporating a ring, at least two of the atoms of which belonging to the peptide skeleton, R1 being either H or a lipophilic chain and R2 being either OH, or a lipophilic chain; and -an acceptable physiological medium. In a preferred peptide the amino acid AA is either a proline P, a ß-proline or a proline derivative Results on the activity of the compounds are obtained and on the general state of the skin and its appendages, in particularvia the stimulation of extracellular matrix components.

    Abstract translation: 本发明提出了一种化妆品组合物，其包含： - 式R 1 -K-AA-K-R 2的肽，其中K代表赖氨酸，AA是掺入环的氨基酸，其至少两个原子属于肽 骨架，R1是H或亲脂链，R2是OH或亲脂链; 和 - 可接受的生理介质。 在优选的肽中，氨基酸AA是脯氨酸P，ß-脯氨酸或脯氨酸衍生物获得化合物的活性的结果，并且在皮肤及其附属物的一般状态下，特别是通过刺激细胞外基质 组件。

    NEW COMPOUNDS, IN PARTICULAR PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMOPHARMACEUTICAL USES
    7.
    发明申请
    NEW COMPOUNDS, IN PARTICULAR PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMOPHARMACEUTICAL USES 审中-公开
    新化合物，特别是肽，包括它们的化合物和化学和非机械性用途的组合物

    公开(公告)号：WO2010082177A2

    公开(公告)日：2010-07-22

    申请号：PCT/IB2010/050192

    申请日：2010-01-15

    Applicant: SEDERMA ,  FOURNIAL, Arnaud ,  MONDON, Philippe ,  PESCHARD, Olivier

    Inventor： FOURNIAL, Arnaud ,  MONDON, Philippe ,  PESCHARD, Olivier

    IPC: C07K5/08 ,  A61K38/06 ,  A61P17/00 ,  A61K8/64 ,  C07K5/09 ,  A61Q19/00

    CPC classification number: C07K5/081 ,  A61K8/64 ,  A61K8/97 ,  A61Q1/06 ,  A61Q5/006 ,  A61Q7/00 ,  A61Q19/00 ,  A61Q19/001 ,  A61Q19/06 ,  A61Q19/08 ,  C07K5/0606 ,  C07K5/06086 ,  C07K5/0815 ,  C07K5/1008 ,  C07K5/1013 ,  C07K5/1019

    Abstract: The present invention relates to the cosmetic and dermopharmaceutical fields. It concerns compounds having the following formula II : R 1 -(AA) n -R 2 (SEQ ID NO 1 to SEQ ID NO 7) wherein: AA is selected from an amino acid, an amino acid derivative and an amino acid analogue; n=1 to 10, when n ≥ 2, the AA can be different and the bonds being of peptidic or peptoidic type; R 1 is either an H or a lipophilic chain, R 2 is either an OH or a lipophilic chain, characterised in that the AA or when n>l at least one of the AA comprise at least one sulfur atom in an oxygenated form, preferably a dioxygenated form. More preferably, AA is a dioxygenated SO2 methionine. Results on the activity of the compounds are obtained and on the general state of the skin and its appendages, especially via the stimulation of extracellular matrix components.

    Abstract translation: 本发明涉及化妆品和皮肤药物领域。 它涉及具有下式II的化合物：R1-（AA）n-R2（SEQ ID NO：1至SEQ ID NO：7）其中：AA选自氨基酸，氨基酸衍生物和氨基酸类似物; n = 1至10，当n = 2时，AA可以不同，并且键是肽或类肽类型; R1是H或亲脂性链，R2是OH或亲脂性链，其特征在于AA或当n≥1时，至少一个AA包含氧化形式的至少一个硫原子，优选为双加氧 形成。 更优选地，AA是二氧化的SO 2甲硫氨酸。 获得化合物活性的结果，以及皮肤及其附属物的一般状态，特别是通过刺激细胞外基质组分。

    COSMETIC COMPOSITION CONTAINING KXK TYPE PEPTIDES AND USES
    8.
    发明申请
    COSMETIC COMPOSITION CONTAINING KXK TYPE PEPTIDES AND USES 审中-公开
    含有KXK型胶囊和使用的化妆品组合物

    公开(公告)号：WO2010082176A2

    公开(公告)日：2010-07-22

    申请号：PCT/IB2010/050191

    申请日：2010-01-15

    Applicant: SEDERMA ,  FOURNIAL, Arnaud ,  MONDON, Philippe ,  PESCHARD, Olivier

    Inventor： FOURNIAL, Arnaud ,  MONDON, Philippe ,  PESCHARD, Olivier

    IPC: C07K5/08 ,  A61K38/06 ,  A61P17/00 ,  A61K8/64 ,  C07K5/09 ,  A61Q19/00

    CPC classification number: C07K5/0815 ,  A61K8/64 ,  A61K38/06 ,  A61Q1/06 ,  A61Q5/006 ,  A61Q5/02 ,  A61Q7/00 ,  A61Q19/00 ,  A61Q19/001 ,  A61Q19/06 ,  A61Q19/08

    Abstract: The invention proposes a cosmetic composition comprising: -a peptide of formula R 1 -K-AA-K-R 2 , in which K represents a lysine and AA an amino acid incorporating a ring, at least two of the atoms of which belonging to the peptide skeleton, R 1 being either H or a lipophilic chain and R 2 being either OH, or a lipophilic chain; and -an acceptable physiological medium. In a preferred peptide the amino acid AA is either a proline P, a β-proline or a proline derivative Results on the activity of the compounds are obtained and on the general state of the skin and its appendages, in particularvia the stimulation of extracellular matrix components.

    Abstract translation: 本发明提出了一种化妆品组合物，其包含： - 式R 1 -K-AA-K-R 2的肽，其中K代表赖氨酸，AA是掺入环的氨基酸，其至少两个原子属于肽 骨架，R1是H或亲脂链，R2是OH或亲脂链; 和 - 可接受的生理介质。 在优选的肽中，氨基酸AA是脯氨酸P，ß-脯氨酸或脯氨酸衍生物获得化合物的活性的结果，并且在皮肤及其附属物的一般状态下，特别是通过刺激细胞外基质 组件。

    COSMETIC USE OF GERANYLGERANYL-2-PROPANOL
    10.
    发明申请
    COSMETIC USE OF GERANYLGERANYL-2-PROPANOL 审中-公开
    GERANYLGERANYL-2-PROPANOL的化妆品用途

    公开(公告)号：WO2011125039A3

    公开(公告)日：2012-03-22

    申请号：PCT/IB2011051498

    申请日：2011-04-07

    Applicant: SEDERMA SA ,  FOURNIAL ARNAUD ,  MONDON PHILIPPE ,  PESCHARD OLIVIER

    Inventor： FOURNIAL ARNAUD ,  MONDON PHILIPPE ,  PESCHARD OLIVIER

    IPC: A61K8/34 ,  A61Q19/08

    CPC classification number: A61Q17/04 ,  A61K8/342 ,  A61Q19/08

    Abstract: Geranylgeranyl-2-propanol compound (GGP) having the following formula (I) is proposed for use according to the present invention as a cosmetic active compound for the prevention and treatment of aging of skin and its appendages. The GGP has a protective action against oxidative stress and free radical, on telomeres and on mitochondria and its activity. In particular, GGP can be used for the treatment of wrinkles, fine lines and visible discontinuities of skin, for the treatment pigmentation disorders.

    Abstract translation: 提出具有下式（I）的香叶基香叶基-2-丙醇化合物（GGP）用作根据本发明用作预防和治疗皮肤老化及其附属物的化妆品活性化合物。 GGP具有抗氧化应激和自由基，端粒和线粒体及其活性的保护作用。 特别地，GGP可用于治疗皱纹，细纹和可见的皮肤不连续性，用于治疗色素沉着障碍。

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