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公开(公告)号：WO2011022690A3
公开(公告)日：2011-02-24
申请号：PCT/US2010/046220
申请日：2010-08-20
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY , SCHERER, Axel , RAJAGOPAL, Aditya , KIM, Seheon , HOMYK, Andrew, P.
Inventor： SCHERER, Axel , RAJAGOPAL, Aditya , KIM, Seheon , HOMYK, Andrew, P.
IPC: H01L31/04
Abstract: The present disclosure describes an optically powered transducer with a photovoltaic collector. An optical fiber power delivery method and system and a free space power delivery method are also provided. A fabrication process for making an optically powered transducer is further described, together with an implantable transducer system based on optical power delivery.
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公开(公告)号：WO2012145301A3
公开(公告)日：2012-12-27
申请号：PCT/US2012033914
申请日：2012-04-17
Applicant: CALIFORNIA INST OF TECHN , CHEN SAMSON , RAJAGOPAL ADITYA , SCHERER AXEL
Inventor： CHEN SAMSON , RAJAGOPAL ADITYA , SCHERER AXEL
CPC classification number: H05K3/10 , B01L3/502707 , B01L3/502715 , B01L2300/0645 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , H01L23/473 , H01L2924/0002 , H05K1/0272 , H05K3/284 , H05K2201/10189 , H05K2203/1327 , Y10T29/49 , Y10T29/49002 , Y10T29/49155 , Y10T29/49165 , Y10T137/85938 , Y10T436/11 , Y10T436/25 , Y10T436/2575 , H01L2924/00
Abstract: A printed circuit board structure is coated with an encapsulant within which microfluidic channels have been formed. The microfluidic channels are formed by soldering fluidic connections to metal traces on a surface of the printed circuit board structure prior to encapsulation. The metal traces are removed by etching after encapsulation to form microchannels within the encapsulant.
Abstract translation: 印刷电路板结构涂覆有密封剂，在密封剂内已经形成微流体通道。 微流体通道通过在封装之前将流体连接焊接到印刷电路板结构的表面上的金属迹线而形成。 在封装后通过蚀刻去除金属迹线以在密封剂内形成微通道。
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3.发明申请
公开(公告)号：WO2012129157A2
公开(公告)日：2012-09-27
申请号：PCT/US2012/029631
申请日：2012-03-19
Inventor： WALKER, Christopher I. , RAJAGOPAL, Aditya
CPC classification number: B01L3/502707 , B01L7/52 , B01L2200/16 , B01L2300/0816 , B01L2300/0887 , B01L2300/1827
Abstract: A printed circuit structure containing a fluidic chamber configured to receive an aqueous solution containing a sample to be analyzed and fluorophore for polymerase chain reaction analysis. The printed circuit structure also contains a heating element that provides for temperature cycling of the fluidic chamber to support polymerase chain reaction analysis.
Abstract translation: 包含流体室的印刷电路结构，所述流体室被配置为接收含有待分析样品的水溶液和用于聚合酶链式反应分析的荧光团。 印刷电路结构还包含加热元件，其提供流体室的温度循环以支持聚合酶链式反应分析。
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4.发明申请
公开(公告)号：WO2007027663A3
公开(公告)日：2007-06-21
申请号：PCT/US2006033653
申请日：2006-08-28
Applicant: CALIFORNIA INST OF TECHN , MALTEZOS GEORGE , RAJAGOPAL ADITYA , SCHERER AXEL
Inventor： MALTEZOS GEORGE , RAJAGOPAL ADITYA , SCHERER AXEL
IPC: H01L23/427 , B81C1/00 , F28D15/04 , H01L23/473
CPC classification number: H01L23/427 , F25B19/00 , F28C3/08 , F28D5/00 , F28D15/0233 , F28D2021/0052 , F28F2260/02 , H01L23/473 , H01L2924/0002 , H01L2924/00
Abstract: Evaporative cooling is an effective and efficient method for rapidly removing heat from a system device. In accordance with the disclosure herein, a microfluidic Y-junction apparatus is provided which can produce low temperatures and can be integrated into microdevices.
Abstract translation: 蒸发冷却是快速从系统设备中去除热量的有效和有效的方法。 根据本文的公开内容，提供了可以产生低温并且可以集成到微器件中的微流控Y接合装置。
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公开(公告)号：WO2020264051A1
公开(公告)日：2020-12-30
申请号：PCT/US2020/039457
申请日：2020-06-24
Applicant: CHROMACODE, INC. , MACDONALD, Christopher , JACKY, Lucien , RAJAGOPAL, Aditya
Inventor： MACDONALD, Christopher , JACKY, Lucien , RAJAGOPAL, Aditya
IPC: C12Q1/68
Abstract: Methods for differentially quantifying nucleic acids in a biological sample using differentially methylated loci include forming a digested biological sample in a solution of a methylation- sensitive restriction enzyme to cleave an unmethylated group of nucleic acids, forming a reaction mixture, amplifying the reaction mixture to generate a first signal from the a group of detection probes and a second signal from a second group of detection probes, determining a ratio comprising a first value derived from the first signal to a second value derived from the second signal, and identifying the proportion of nucleic acid in the biological sample originating from the first plurality of nucleic acids.
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Patent Agency Ranking6.发明申请
公开(公告)号：WO2012129157A3
公开(公告)日：2012-12-27
申请号：PCT/US2012029631
申请日：2012-03-19
Applicant: CALIFORNIA INST OF TECHN , WALKER CHRISTOPHER I , RAJAGOPAL ADITYA
Inventor： WALKER CHRISTOPHER I , RAJAGOPAL ADITYA
CPC classification number: B01L3/502707 , B01L7/52 , B01L2200/16 , B01L2300/0816 , B01L2300/0887 , B01L2300/1827
Abstract: A printed circuit structure containing a fluidic chamber configured to receive an aqueous solution containing a sample to be analyzed and fluorophore for polymerase chain reaction analysis. The printed circuit structure also contains a heating element that provides for temperature cycling of the fluidic chamber to support polymerase chain reaction analysis.
Abstract translation: 一种包含流化室的印刷电路结构，其配置为接收含有待分析样品的水溶液和用于聚合酶链式反应分析的荧光团。 印刷电路结构还包含加热元件，其提供流体室的温度循环以支持聚合酶链式反应分析。
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公开(公告)号：WO2012145301A2
公开(公告)日：2012-10-26
申请号：PCT/US2012/033914
申请日：2012-04-17
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY , CHEN, Samson , RAJAGOPAL, Aditya , SCHERER, Axel
Inventor： CHEN, Samson , RAJAGOPAL, Aditya , SCHERER, Axel
CPC classification number: H05K3/10 , B01L3/502707 , B01L3/502715 , B01L2300/0645 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , H01L23/473 , H01L2924/0002 , H05K1/0272 , H05K3/284 , H05K2201/10189 , H05K2203/1327 , Y10T29/49 , Y10T29/49002 , Y10T29/49155 , Y10T29/49165 , Y10T137/85938 , Y10T436/11 , Y10T436/25 , Y10T436/2575 , H01L2924/00
Abstract: A printed circuit board structure is coated with an encapsulant within which microfluidic channels have been formed. The microfluidic channels are formed by soldering fluidic connections to metal traces on a surface of the printed circuit board structure prior to encapsulation. The metal traces are removed by etching after encapsulation to form microchannels within the encapsulant.
Abstract translation: 印刷电路板结构涂覆有已经形成微流体通道的密封剂。 在封装之前，通过将流体连接焊接到印刷电路板结构的表面上的金属迹线来形成微流体通道。 在封装后通过蚀刻去除金属迹线，以在密封剂内形成微通道。
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公开(公告)号：WO2012045016A3
公开(公告)日：2012-07-12
申请号：PCT/US2011054366
申请日：2011-09-30
Applicant: CALIFORNIA INST OF TECHN , WALAVALKAR SAMEER , RAJAGOPAL ADITYA , SCHERER AXEL , TOMBRELLO THOMAS A
Inventor： WALAVALKAR SAMEER , RAJAGOPAL ADITYA , SCHERER AXEL , TOMBRELLO THOMAS A
CPC classification number: B01D67/0062 , B01D61/027 , B01D61/145 , B01D69/06 , B01D71/027 , B07B1/00 , B07B1/4618 , B81C1/00031 , B81C1/00111 , B81C1/00119 , B81C1/00158 , B81C1/00531 , B81C1/00539 , B82Y40/00 , G01N33/48721 , H01L21/0331
Abstract: Methods and devices for isolating and sorting nanoparticles are disclosed herein. Nanopores of a desired size can be formed in silicon dioxide membranes and used as filters to separate nanoparticles. Devices are also provided herein for sorting nanoparticles with multiple filters having various sized nanopores.
Abstract translation: 本文公开了用于分离和分选纳米颗粒的方法和装置。 所需尺寸的纳米孔可以在二氧化硅膜中形成并用作分离纳米颗粒的过滤器。 本文还提供了用于对具有各种尺寸的纳米孔的多个过滤器分选纳米颗粒的装置。
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公开(公告)号：WO2012045016A2
公开(公告)日：2012-04-05
申请号：PCT/US2011/054366
申请日：2011-09-30
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY , WALAVALKAR, Sameer , RAJAGOPAL, Aditya , SCHERER, Axel , TOMBRELLO, Thomas, A.
Inventor： WALAVALKAR, Sameer , RAJAGOPAL, Aditya , SCHERER, Axel , TOMBRELLO, Thomas, A.
CPC classification number: B01D67/0062 , B01D61/027 , B01D61/145 , B01D69/06 , B01D71/027 , B07B1/00 , B07B1/4618 , B81C1/00031 , B81C1/00111 , B81C1/00119 , B81C1/00158 , B81C1/00531 , B81C1/00539 , B82Y40/00 , G01N33/48721 , H01L21/0331
Abstract: Methods and devices for isolating and sorting nanoparticles are disclosed herein. Nanopores of a desired size can be formed in silicon dioxide membranes and used as filters to separate nanoparticles. Devices are also provided herein for sorting nanoparticles with multiple filters having various sized nanopores.
Abstract translation: 本文公开了用于分离和分选纳米粒子的方法和装置。 所需尺寸的纳米孔可以在二氧化硅膜中形成并用作过滤器以分离纳米粒子。 本文还提供了用于利用具有各种尺寸的纳米孔的多个过滤器对纳米颗粒进行分选的装置。
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公开(公告)号：WO2012044857A3
公开(公告)日：2012-07-19
申请号：PCT/US2011054074
申请日：2011-09-29
Applicant: CALIFORNIA INST OF TECHN , RAJAGOPAL ADITYA , SCHERER AXEL , TOMBRELLO THOMAS A , WALAVALKAR SAMEER , HOMYK ANDREW P , GARCIA ERIKA
Inventor： RAJAGOPAL ADITYA , SCHERER AXEL , TOMBRELLO THOMAS A , WALAVALKAR SAMEER , HOMYK ANDREW P , GARCIA ERIKA
CPC classification number: G01N27/447 , B82Y30/00 , C12Q1/6869 , G01N33/48721 , C12Q2563/116 , C12Q2565/631
Abstract: Methods and devices for sequencing nucleic acids are disclosed herein. Devices are also provided herein for measuring DNA with nano-pores sized to allow DNA to pass through the nano-pore. The capacitance can be measured for the DNA molecule passing through the nano-pore. The capacitance measurements can be correlated to determine the sequence of base pairs passing through the nano-pore to sequence the DNA.
Abstract translation: 本文公开了用于测序核酸的方法和装置。 本文还提供了用于测量具有大小允许DNA穿过纳米孔的纳米孔的DNA的装置。 可以测量通过纳米孔的DNA分子的电容。 电容测量可以相关，以确定通过纳米孔的碱基对序列来对DNA进行排序。
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