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    BALLOON-TIPPED CATHETER FOR CONTINUOUS NERVE BLOCKS
    1.
    发明申请
    BALLOON-TIPPED CATHETER FOR CONTINUOUS NERVE BLOCKS 审中-公开
    用于连续神经阻滞的气囊导管

    公开(公告)号：WO2016150448A1

    公开(公告)日：2016-09-29

    申请号：PCT/DK2016/050089

    申请日：2016-03-22

    Applicant: RIGSHOSPITALET COPENHAGEN UNIVERSITY HOSPITAL

    Inventor： HESSELBJERG, Lars

    IPC: A61M25/00 ,  A61M19/00 ,  A61M29/02 ,  A61M25/06

    CPC classification number: A61M25/0074 ,  A61M19/00 ,  A61M25/0075 ,  A61M25/065 ,  A61M25/10 ,  A61M29/02 ,  A61M2025/105

    Abstract: The invention relates to a catheter (1) for administering anaesthetics to a peripheral nerve site in a patient. The catheter (1) comprises a hollow, flexible catheter tube (2) having a first inner lumen (3) extending along a longitudinal axis of the catheter tube (2) from a proximal end (4) to a distal end (5) where a balloon (6) is arranged. The balloon (6) is adapted to be inflated from a collapsed state to an inflated state by a fluid fed through the catheter tube (2) into an inner cavity (7) of the balloon (6). The inflated balloon (6) is used to ensure that the distal end of the catheter (1) stays at the desired position at the peripheral nerve site. The catheter (1) may comprise a second lumen (10), so that the balloon (6) is inflated via one lumen and the anaesthetics is administered via the other lumen. The invention further relates to a needle-catheter kit and for a method of administering anaesthetics by use of such a catheter.

    Abstract translation: 本发明涉及一种用于向患者的周围神经部位施用麻醉剂的导管（1）。 导管（1）包括中空的柔性导管（2），其具有沿着导管（2）的纵向轴线从近端（4）延伸到远端（5）的第一内腔（3） 设置气球（6）。 气球（6）适于通过通过导管（2）供给到气囊（6）的内腔（7）中的流体从收缩状态膨胀至膨胀状态。 充气气球（6）用于确保导管（1）的远端停留在周围神经部位的期望位置。 导管（1）可以包括第二腔（10），使得球囊（6）经由一个腔膨胀，并且麻醉剂经由另一个内腔施用。 本发明还涉及一种针导管试剂盒以及使用这种导管给药麻醉药的方法。

    SYSTEM AND METHOD FOR INJECTING A SUBSTANCE INTO A HUMAN BODY
    4.
    发明申请
    SYSTEM AND METHOD FOR INJECTING A SUBSTANCE INTO A HUMAN BODY 审中-公开
    将物质注入人体内的系统和方法

    公开(公告)号：WO2012139593A3

    公开(公告)日：2013-01-17

    申请号：PCT/DK2012050129

    申请日：2012-04-16

    Applicant: RIGSHOSPITALET COPENHAGEN UNIVERSITY HOSPITAL ,  LUMHOLT PAVIA CHRISTOFFER

    Inventor： LUMHOLT PAVIA CHRISTOFFER

    IPC: A61M5/46

    CPC classification number: A61M5/46 ,  A61M5/142 ,  A61M5/14216 ,  A61M5/14228 ,  A61M5/1452 ,  A61M2202/08 ,  A61M2205/50 ,  A61M2206/22 ,  A61M2210/1007

    Abstract: A system for injecting a substance into a human body comprises a tubular member (1105) with an outlet opening for injecting the substance, a pump with an inlet connectable to a supply of the substance and to receive the substance from the supply, and an outlet connectable to the tubular member for delivering the substance to the tubular member, means (1106) for sensing a movement and/or a position of the tubular member relative to the body, and control means for controlling the pumpto deliver the substance at a rate related to the sensed movement and/or position of the tubular member relative to the body. The system is particularly useful for injecting a filler substance such as adipose tissue cells or a synthetic filling substance for cosmetic, reconstructive or otherwise therapeutic purposes.

    Abstract translation: 用于将物质注入人体的系统包括具有用于注射物质的出口的管状构件（1105），具有可连接到物质供应并从供应物接收物质的入口的泵，以及出口 可连接到用于将物质输送到管状构件的管状构件，用于感测管状构件相对于身体的移动和/或位置的装置（1106），以及用于控制泵以相关速率输送物质的控制装置 相对于管状构件相对于身体感测到的移动和/或位置。 该系统特别可用于注射诸如脂肪组织细胞或合成填充物质的填充物质用于化妆品，重建或其它治疗目的。

    ACTIVE VITAMIN D OR ANALOGS THEREOF FOR USE IN IN VIVO OR IN VITRO FERTILIZATION
    6.
    发明申请
    ACTIVE VITAMIN D OR ANALOGS THEREOF FOR USE IN IN VIVO OR IN VITRO FERTILIZATION 审中-公开
    活体维生素D或其用于体外或体外培养的模拟物

    公开(公告)号：WO2012116699A1

    公开(公告)日：2012-09-07

    申请号：PCT/DK2012/050040

    申请日：2012-01-31

    Applicant: RIGSHOSPITALET COPENHAGEN UNIVERSITY HOSPITAL ,  JENSEN, Martin Blomberg

    Inventor： JENSEN, Martin Blomberg

    IPC: C12N5/076

    CPC classification number: A61K31/59 ,  A61K35/52 ,  C12N5/061 ,  C12N2500/38 ,  C12N2517/10

    Abstract: The present invention relates to methods for improving the ability of spermatozoa to fertilize an egg in vitro and/or vivo, said method comprising providing a medium comprising active vitamin D (calcitriol) or analogs thereof, providing a sample of spermatozoa, and incubating said sample of spermatozoa with said medium. In addition, the invention relates to compositions comprising active vitamin D or analogs thereof for use in the treatment of infertility in a male or female subject.

    Abstract translation: 本发明涉及提高精子在体外和/或体内施肥卵的能力的方法，所述方法包括提供包含活性维生素D（骨化三醇）或其类似物的培养基，提供精子样品，并将所述样品 的精子与所述培养基。 此外，本发明涉及包含活性维生素D或其类似物的组合物，其用于治疗男性或女性受试者的不育症。

    TEST FOR MALE FERTILITY
    7.
    发明申请
    TEST FOR MALE FERTILITY 审中-公开
    男性性欲测试

    公开(公告)号：WO2011137906A1

    公开(公告)日：2011-11-10

    申请号：PCT/DK2011/050150

    申请日：2011-05-03

    Applicant: RIGSHOSPITALET COPENHAGEN UNIVERSITY HOSPITAL ,  JENSEN, Martin, Blomberg ,  NIELSEN, John, Erik ,  JØRGENSEN, Niels ,  ALMSTRUP, Kristian ,  LEFFERS, Henrik

    Inventor： JENSEN, Martin, Blomberg ,  NIELSEN, John, Erik ,  JØRGENSEN, Niels ,  ALMSTRUP, Kristian ,  LEFFERS, Henrik

    IPC: G01N33/68

    CPC classification number: G01N33/689 ,  G01N33/82

    Abstract: The present invention relates generally to a method for predicting the fertility potential in a male mammal. In particular it relates to a method for predicting the fertility potential in a male mammal by determining the expression of at least one protein of the vitamin D metabolising machinery in a semen sample. The expression level of the at least one protein of the vitamin D metabolising machinery is then indicative of the fertility potential of the subject. An object of the present invention relates to a method, which can predict whether the semen quality is sufficient to achieve pregnancy spontaneously or if the couple should proceed to assisted reproduction or further investigation.

    Abstract translation: 本发明一般涉及一种用于预测男性哺乳动物中的生殖能力的方法。 特别地，本发明涉及一种通过测定精液样品中至少一种维生素D代谢机制蛋白质的表达来预测男性哺乳动物的生殖能力的方法。 维生素D代谢机制的至少一种蛋白质的表达水平然后指示受试者的生殖能力。 本发明的目的在于一种方法，其可以预测精液质量是否足以自发实现怀孕，或者夫妇是否应进行辅助生殖或进一步调查。

    THERMAL SHIELD FOR A NEWBORN INFANT
    8.
    发明申请
    THERMAL SHIELD FOR A NEWBORN INFANT 审中-公开
    新生婴儿的热屏蔽

    公开(公告)号：WO2011134475A1

    公开(公告)日：2011-11-03

    申请号：PCT/DK2011/050138

    申请日：2011-04-28

    Applicant: RIGSHOSPITALET COPENHAGEN UNIVERSITY HOSPITAL ,  BREINDAHL, Morten ,  WEISENFELD, Berit, Bay

    Inventor： BREINDAHL, Morten ,  WEISENFELD, Berit, Bay

    IPC: A41B13/06 ,  A41D13/12 ,  G01K1/14 ,  A61F7/02

    CPC classification number: A41B13/06 ,  A41B2400/52 ,  A41D13/1272 ,  A41D2400/10 ,  A41D2400/422 ,  G01K13/00 ,  G01K2217/00

    Abstract: The present invention relates to a thermal shield 1 for at least partly surrounding a newborn infant by the shield 1 to protect it from undesired cooling or heating. The shield 1 comprises a first layer 3 and a second layer 4 both of a transparent material, which layers 3,4 are joined so that there is at least one air containing pocket 5 between the layers 3,4. When the thermal shield 1 is in use, the mutual arrangement of the first and second layers 3,4 allows the at least one pocket to be deformable to an amount necessary for establishment of acoustic contact between the skin of the infant 10 and an acoustic transducer 11 placed on an outer surface of the second layer 4. In some embodiments of the thermal shield, the at least one air containg pocket 5 is air tight, and acoustic contact can be established over an area of at least 1 cm 2 . In other embodiments, there is at least one open passage 13 from the surroundings and into each of the at least one air pocket 5 between the first and second layers 3,4, and the compliance of the first layer 3 is higher than the complicance of the second layer 4 so that when an infant is placed in the shield 1, the first layer 3 clings around the infant while the second layer 4 deforms to a lesser extent than the first layer 3 so that air from the surroundings flows into the at least one air pocket 5 via the open passage 13.

    Abstract translation: 本发明涉及一种用于通过屏蔽件1至少部分地围绕新生儿以防止不期望的冷却或加热的热屏蔽1。 屏蔽层1包括第一层3和第二层4，两者都是透明材料，层3,4连接成使得在层3,4之间存在至少一个包含袋5的空气。 当使用热屏蔽1时，第一和第二层3,4的相互排列允许至少一个口袋可变形到建立婴儿10的皮肤和声学换能器之间的声学​​接触所需的量 11放置在第二层4的外表面上。在热屏蔽的​​一些实施例中，至少一个包含空气的口袋5是气密的，并且可以在至少1cm 2的面积上建立声学接触。 在其它实施例中，从周围至少有一个开放通道13和在第一和第二层3,4之间的至少一个气穴5中的每一个中，并且第一层3的顺应性高于 第二层4使得当婴儿被放置在护罩1中时，第一层3附着在婴儿周围，而第二层4变形到比第一层3更小的程度，使得来自周围的空气流入至少 一个气囊5经由开放通道13。

    SYSTEM AND METHOD FOR INJECTING A SUBSTANCE INTO A HUMAN BODY
    9.
    发明申请
    SYSTEM AND METHOD FOR INJECTING A SUBSTANCE INTO A HUMAN BODY 审中-公开
    将物质注入人体内的系统和方法

    公开(公告)号：WO2012139593A2

    公开(公告)日：2012-10-18

    申请号：PCT/DK2012/050129

    申请日：2012-04-16

    Applicant: RIGSHOSPITALET COPENHAGEN UNIVERSITY HOSPITAL ,  LUMHOLT, Pavia Christoffer

    Inventor： LUMHOLT, Pavia Christoffer

    IPC: A61M5/46

    CPC classification number: A61M5/46 ,  A61M5/142 ,  A61M5/14216 ,  A61M5/14228 ,  A61M5/1452 ,  A61M2202/08 ,  A61M2205/50 ,  A61M2206/22 ,  A61M2210/1007

    Abstract: A system for injecting a substance into a human body comprises a tubular member with an outlet opening for injecting the substance, a pump with an inlet connectable to a supply of the substance and to receive the substance from the supply, and an outlet connectable to the tubular member for delivering the substance to the tubular member, means for sensing a movement and/or a position of the tubular member relative to the body, and control means for controlling the pumpto deliver the substance at a rate related to the sensed movement and/or position of the tubular member relative to the body. The system is particularly useful for injecting a filler substance such as adipose tissue cells or a synthetic filling substance for cosmetic, reconstructive or otherwise therapeutic purposes.

    Abstract translation: 用于将物质注入人体的系统包括具有用于注射物质的出口的管状构件，具有可连接到物质供应并可从供应物接收物质的入口的泵，以及可连接到物体的出口 用于将物质输送到管状构件的管状构件，用于感测管状构件相对于身体的运动和/或位置的装置，以及用于控制泵以与感测到的移动相关的速率和/ 或管状构件相对于主体的位置。 该系统特别可用于注射诸如脂肪组织细胞的填充物质或用于化妆品，重建或其它治疗目的的合成填充物质。

    WOUND CARE PRODUCTS
    10.
    发明申请
    WOUND CARE PRODUCTS 审中-公开
    创伤护理产品

    公开(公告)号：WO2011076216A2

    公开(公告)日：2011-06-30

    申请号：PCT/DK2010050352

    申请日：2010-12-21

    Applicant: RIGSHOSPITALET COPENHAGEN UNIVERSITY HOSPITAL ,  UNIV DANMARKS TEKNISKE ,  BISPEBJERG HOSPITAL ,  GIVSKOV MICHAEL CHRISTIAN ,  BJARNSHOLT THOMAS ,  KIRKETERP-MOELLER KLAUS

    Inventor： GIVSKOV MICHAEL CHRISTIAN ,  BJARNSHOLT THOMAS ,  KIRKETERP-MOELLER KLAUS

    IPC: A61K9/08 ,  A61K9/00 ,  A61K47/12

    CPC classification number: A61K9/0014 ,  A61F13/00068 ,  A61L15/46 ,  A61L26/0066 ,  A61L26/0076 ,  A61L2300/404 ,  A61L2300/406 ,  A61M1/0088 ,  A61M27/00

    Abstract: The present invention relates to wound care products, devices and methods incorporating acetic acid for the treatment of bacterial infections, in particular bacterial biofilm infections. In particular it relates to a wound care product comprising acetic acid, wherein the product comprises at least one further antibacterial compound; a delivery system comprising a container connected to a means of delivery which is connected to a pad, wherein said container comprises a composition comprising acetic acid and said pad comprises a self-adhesive material; a kit comprising a dressing and an adhesive membrane, wherein the dressing comprises a composition comprising acetic acid; a method of treating a wound comprising a) applying acetic acid to the wound and b) applying a negative pressure to the wound.

    Abstract translation: 本发明涉及包含乙酸用于治疗细菌感染，特别是细菌生物膜感染的伤口护理产品，装置和方法。 特别地，其涉及包含乙酸的伤口护理产品，其中该产品包含至少一种其它抗菌化合物; 输送系统，包括连接到输送装置的容器，所述容器连接到垫，其中所述容器包括包含乙酸的组合物，所述垫包括自粘合材料; 包括敷料和粘合剂膜的试剂盒，其中所述敷料包含包含乙酸的组合物; 一种治疗伤口的方法，包括：a）向伤口施用乙酸，b）向伤口施加负压。

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