METABOLIC METHOD TO IDENTIFY COMPOUNDS
    5.
    发明申请
    METABOLIC METHOD TO IDENTIFY COMPOUNDS 审中-公开
    代谢化合物的代谢方法

    公开(公告)号:WO2006007751A2

    公开(公告)日:2006-01-26

    申请号:PCT/CH2005000411

    申请日:2005-07-15

    Inventor: SCHILLING BORIS

    Abstract: The invention is concerned with the identification of compounds as flavours or fragrances, their precursors, or as modulators of the perception of fragrances or flavours. The method comprises a reaction of a compound with a metabolic enzyme expressed in the nose, mouth or respiratory tract, followed by a method of identification of the compound or its metabolites as a fragrance or flavour, their precursor, or a modulator of their perception or of the perception of their respective leads.

    Abstract translation: 本发明涉及将化合物鉴定为香料或香料,其前体,或作为香料或调味剂感觉的调节剂。 该方法包括化合物与在鼻,口或呼吸道中表达的代谢酶的反应,随后是将化合物或其代谢物鉴定为香料或调味剂,其前体或其感知或调节剂的方法 对各自领导的看法。

    METABOLIC METHOD TO IDENTIFY FLAVOURS AND/OR FRAGRANCES

    公开(公告)号:WO2006007751A3

    公开(公告)日:2006-01-26

    申请号:PCT/CH2005/000411

    申请日:2005-07-15

    Inventor: SCHILLING, Boris

    Abstract: The invention is concerned with the identification of compounds as flavours or fragrances, their precursors, or as modulators of the perception of fragrances or flavours. The method comprises a reaction of a compound with a metabolic enzyme expressed in the nose, mouth or respiratory tract, followed by the identification of the compound or its metabolites as a fragrance or flavour by means of a chemorecector assay, their precursor, or a modulator of their perception or of the perception of their respective leads.

    ORGANIC COMPOUNDS
    8.
    发明申请
    ORGANIC COMPOUNDS 审中-公开
    有机化合物

    公开(公告)号:WO2010037244A2

    公开(公告)日:2010-04-08

    申请号:PCT/CH2009/000311

    申请日:2009-09-29

    CPC classification number: C07D213/40 A61L9/01 C07D233/61

    Abstract: Disclosed are compounds having the ability to modulate, namely to improve, enhance and/or modify fragrance compositions due to their ability to inhibit cytochrome P450 enzymes, e.g. CYP2A, e.g. 2A13 and 2A6, and CYP2B6.

    Abstract translation: 公开了具有调节,即改善,增强和/或改善香料组合物的能力的化合物,因为它们抑制细胞色素P450酶的能力,例如, CYP2A,例如 2A13和2A6,以及CYP2B6。

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