-
1.发明申请POLYNUCLEOTIDES OF DHA AND ISOFORMS OF EIF-5A AND METHODS OF USING SAME 审中-公开DHA的多核苷酸和EIF-5A的ISOFORMS及其使用方法
公开(公告)号：WO2006060699A9
公开(公告)日：2006-08-24
申请号：PCT/US2005043708
申请日：2005-12-05
Applicant: SENESCO TECHNOLOGIES INC
Inventor： THOMPSON JOHN E
IPC: C12N15/82 , C07K14/415
CPC classification number: C12N15/8261 , C07K14/415 , Y02A40/146
Abstract: The present invention relates to unique isoforms of eukaryotic initiation Factor 5A ("eIF-5A"): senescence-induced eIF-5A; wounding/pathogen induced eIF-5A; stress eIF-5A and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the expression of these factors. The present invention also relates to deoxyhypusine synthase ("DHS"), polynucleotides that encode DHS, and methods involving modulating the expression of DHS.
Abstract translation: 本发明涉及真核起始因子5A（“eIF-5A”）的独特同工型：衰老诱导的eIF-5A; 伤员/病原体诱导eIF-5A; 应激eIF-5A和生长eIF-5A，以及编码这三个因子的多核苷酸。 本发明还涉及涉及调节这些因子的表达的方法。 本发明还涉及脱氧螺旋体合成酶（“DHS”），编码DHS的多核苷酸以及涉及调节DHS表达的方法。
-
公开(公告)号：WO2006060699A3
公开(公告)日：2006-06-08
申请号：PCT/US2005/043708
申请日：2005-12-05
Applicant: SENESCO TECHNOLOGIES, INC.
Inventor： THOMPSON, John, E.
IPC: C12N15/82 , C07K14/415
Abstract: Methods of increasing seed yield in plants using vectors incorporating either an antisense polynucleotide of DHS or a sense polynucleotide of eIF-SA
-
3.发明申请POLYNUCLEOTIDES OF DHA AND ISOFORMS OF EIF-5A AND METHODS OF USING SAME 审中-公开DHA的多核苷酸和EIF-5A的异构体及其使用方法
公开(公告)号：WO2006060699A2
公开(公告)日：2006-06-08
申请号：PCT/US2005043708
申请日：2005-12-05
Applicant: SENESCO TECHNOLOGIES INC
Inventor： THOMPSON JOHN E
CPC classification number: C12N15/8261 , C07K14/415 , Y02A40/146
Abstract: The present invention relates to unique isoforms of eukaryotic initiation Factor 5A ("eIF-5A"): senescence-induced eIF-5A; wounding/pathogen induced eIF-5A; stress eIF-5A and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the expression of these factors. The present invention also relates to deoxyhypusine synthase ("DHS"), polynucleotides that encode DHS, and methods involving modulating the expression of DHS.
Abstract translation: 本发明涉及真核起始因子5A（“eIF-5A”）的独特同种型：衰老诱导的eIF-5A; 创伤/病原体诱导的eIF-5A; 应激eIF-5A和生长eIF-5A，以及编码这三种因子的多核苷酸。 本发明还涉及涉及调节这些因子表达的方法。 本发明还涉及脱氧前苏氨酸合酶（“DHS”），编码DHS的多核苷酸和涉及调节DHS表达的方法。
-
4.发明申请
公开(公告)号：WO2006014752A3
公开(公告)日：2006-02-09
申请号：PCT/US2005/025766
申请日：2005-07-20
Applicant: SENESCO TECHNOLOGIES, INC.
Inventor： THOMPSON, John, E.
IPC: C12N15/11
Abstract: The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis-specific eIF-5A or eIF5-A1, nucleic acids and polypeptides and methods for inhibiting or suppressing apoptosis in cells using antisense nucleotides or siRNAs to inhibit expression of apoptosis-specific eIF-5A. The invention also relates to suppressing or inhibiting expression of pro-inflammatory cytokines or inhibiting activation of NFkB by inhibiting expression of apoptosis-specific eIF-5A.
-
5.发明申请ISOFORMS OF ELF-5A: SENESCENCE-INDUCED ELF5A; WOUNDING-INDUCED ELF-5A; GROWTH ELF-5A; AND DHS 审中-公开ELF-5A的ISOFORMS：敏感性ELF5A; 绕线诱导型ELF-5A; 生长ELF-5A; 和DHS
公开(公告)号：WO2004113528A2
公开(公告)日：2004-12-29
申请号：PCT/US2004/019840
申请日：2004-06-21
Applicant: SENESCO TECHNOLOGIES, INC. , THOMPSON, John, E.
Inventor： THOMPSON, John, E.
IPC: C12N15/00
CPC classification number: C07K14/4705 , C07K14/415 , C12N9/0004 , C12N15/8249 , C12N15/8266 , C12N15/8271
Abstract: The present invention relates to unique isoforms of eukaryotic initiation Factor 5A ("eIF-5A"): senescence-induced eIF-5A; wounding-induced eIF-5A; and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the expression of these factors. The present invention also relates to deoxyhypusine synthase ("DHS"), polynucleotides that encode DHS, and methods involving modulating the expression of DHS.
Abstract translation: 本发明涉及真核起始因子5A（“eIF-5A”）的独特同工型：衰老诱导的eIF-5A; 伤员诱导的eIF-5A; 和生长eIF-5A，以及编码这三个因子的多核苷酸。 本发明还涉及涉及调节这些因子的表达的方法。 本发明还涉及脱氧螺旋体合成酶（“DHS”），编码DHS的多核苷酸以及涉及调节DHS表达的方法。
-
Patent Agency Ranking6.发明申请DNA ENCODING A PLANT DEOXYHYPUSINE SYNTHASE, A PLANT EUKARYOTIC INITIATION FACTOR 5A, TRANSGENIC PLANTS AND A METHOD FOR CONTROLLING SENESCENCE PROGRAMMED AND CELL DEATH IN PLANTS 审中-公开编码植物脱氧胞嘧啶合成酶的DNA，植物真核起始因子5A，转基因植物以及用于控制植物中的衰老程序化和细胞死亡的方法
公开(公告)号：WO0244392A9
公开(公告)日：2003-10-02
申请号：PCT/US0144505
申请日：2001-11-29
Applicant: SENESCO TECHNOLOGIES INC , THOMPSON JOHN E , WANG TZANN-WEI , LU DONGEN LILY
Inventor： THOMPSON JOHN E , WANG TZANN-WEI , LU DONGEN LILY
CPC classification number: C12N9/0004 , C12N15/8249 , C12N15/8266
Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced eIF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhpusine synthase and senescence-induced elF-5A are identified and the nucleotide sequences of each, aon and in combination are used to modify senescence in transgenic plants
Abstract translation: 通过将编码衰老诱导的eIF-5A或两者的基因或基因片段以反义方向整合到植物基因组中实现对植物中程序性细胞死亡（包括衰老）的表达的调节。 鉴定了编码衰老诱导的脱氧合成酶和衰老诱导的eIF-5A的植物基因，并且使用每个aon和其组合中的核苷酸序列来修饰转基因植物中的衰老
-
公开(公告)号：WO2011133866A3
公开(公告)日：2012-02-23
申请号：PCT/US2011033585
申请日：2011-04-22
Applicant: SENESCO TECHNOLOGIES INC , LOUCAS HOLLY , WANG TZANN-WEI , THOMPSON JOHN
Inventor： LOUCAS HOLLY , WANG TZANN-WEI , THOMPSON JOHN
CPC classification number: C12P7/649 , C11B1/04 , C12N9/0004 , C12N15/8247 , C12P7/6463 , Y02E50/13
Abstract: The present invention provides transgenic algal cells that produce an increased amount of oil, methods of making transgenic algal cells, and methods of obtaining biofuel from the transgenic algal cells.
Abstract translation: 本发明提供了产生增加量的油的转基因藻细胞，制备转基因藻类细胞的方法以及从转基因藻细胞获得生物燃料的方法。
-
公开(公告)号：WO2009114487A2
公开(公告)日：2009-09-17
申请号：PCT/US2009036583
申请日：2009-03-09
Applicant: SENESCO TECHNOLOGIES INC , DONDERO RICHARD S , THOMPSON JOHN E , TAYLOR CATHERINE A
Inventor： DONDERO RICHARD S , TAYLOR CATHERINE A
IPC: A61K48/00 , C07H21/02 , C12N15/113 , C12N15/63
CPC classification number: C12N15/113 , A61K48/0008 , C07K14/4702 , C12N15/85 , C12N15/88 , C12N2310/14 , C12N2320/31
Abstract: The present invention relates to the combinatorial use of an siRNA targeted against an endogenous gene to knock out or knock down expression of the endogenous gene in a host and a delivery of a polynucleotide encoding the gene in a delivery vehicle/expression vector to the host to provide expression in the host of the protein encoded by the polynucleotide.
-
9.发明申请
公开(公告)号：WO2007109677A3
公开(公告)日：2008-04-24
申请号：PCT/US2007064424
申请日：2007-03-20
Applicant: SENESCO TECHNOLOGIES INC
Inventor： THOMPSON JOHN E , DINARELLO CHARLES A
IPC: A61K31/7088 , C07K14/47 , C12N5/071 , C12N15/113
CPC classification number: A61K31/7088 , C12N5/0676 , C12N15/113 , C12N2310/14
Abstract: The present invention relates to methods for improving the viability and recovery of islets that are separated from a donor organ for subsequent transplantation and more particularly relates to the use of eIF5A siRNAs to enhance the viability of islets.
Abstract translation: 本发明涉及用于改善从用于随后移植的供体器官分离的胰岛的活力和恢复的方法，更具体地涉及使用eIF5A siRNA来增强胰岛的活力。
-
10.发明申请
公开(公告)号：WO2007109677A2
公开(公告)日：2007-09-27
申请号：PCT/US2007/064424
申请日：2007-03-20
Applicant: SENESCO TECHNOLOGIES, INC.
Inventor： THOMPSON, John E. , DINARELLO, Charles A.
CPC classification number: A61K31/7088 , C12N5/0676 , C12N15/113 , C12N2310/14
Abstract: The present invention relates to methods for improving the viability and recovery of islets that are separated from a donor organ for subsequent transplantation and more particularly relates to the use of eIF5A siRNAs to enhance the viability of islets.
Abstract translation: 本发明涉及用于改善从用于随后移植的供体器官分离的胰岛的活力和恢复的方法，更具体地涉及使用eIF5A siRNA来增强胰岛的活力。
-
-
-
-
-
-
-
-
-
Search Results
41
records
(took 0.016 seconds)
