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1.发明申请DNA SEQUENCING BY SYNTHESIS USING MODIFIED NUCLEOTIDES AND NANOPORE DETECTION 审中-公开通过使用修饰的核苷酸和纳米RNA检测合成DNA
公开(公告)号：WO2012083249A2
公开(公告)日：2012-06-21
申请号：PCT/US2011065640
申请日：2011-12-16
Applicant: UNIV COLUMBIA , JU JINGYUE , KUMAR SHIV , LI ZENGMIN , TAO CHUANJUAN , CHIEN MINCHEN , RUSSO JAMES J , KALACHIKOV SERGEY , SHEPARD KEN , ROSENSTEIN JACOB KARL
Inventor： JU JINGYUE , KUMAR SHIV , LI ZENGMIN , TAO CHUANJUAN , CHIEN MINCHEN , RUSSO JAMES J , KALACHIKOV SERGEY , SHEPARD KEN , ROSENSTEIN JACOB KARL
CPC classification number: C12Q1/6869 , C07H19/10 , C07H21/00 , G01N33/48721 , C12Q2525/113 , C12Q2525/117 , C12Q2565/518 , C12Q2565/631
Abstract: This disclosure is related to a method of sequencing a single- stranded DNA using deoxynucleotide polyphosphate analogues and translocation of tags from incorporated deoxynucleotide polyphosphate analogues through a nanopore.
Abstract translation: 本公开涉及使用脱氧核苷酸多磷酸酯类似物测序单链DNA的方法和通过纳米孔从掺入的脱氧核苷酸多磷酸酯类似物转移标签的方法。
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公开(公告)号：WO2012083249A3
公开(公告)日：2012-06-21
申请号：PCT/US2011/065640
申请日：2011-12-16
Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK , JU, Jingyue , KUMAR, Shiv , LI, Zengmin , TAO, Chuanjuan , CHIEN, Minchen , RUSSO, James, J. , KALACHIKOV, Sergey , SHEPARD, Ken , ROSENSTEIN, Jacob, Karl
Inventor： JU, Jingyue , KUMAR, Shiv , LI, Zengmin , TAO, Chuanjuan , CHIEN, Minchen , RUSSO, James, J. , KALACHIKOV, Sergey , SHEPARD, Ken , ROSENSTEIN, Jacob, Karl
IPC: C12Q1/68
Abstract: This disclosure is related to a method of sequencing a single- stranded DNA using deoxynucleotide polyphosphate analogues and translocation of tags from incorporated deoxynucleotide polyphosphate analogues through a nanopore.
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