摘要:
The specification relates to a self-pipelining workflow management system. The system can receive a request to run a bioinformatics analysis and automatically create a workflow by accessing a knowledge structure. The knowledge structure can include a plurality of predicates describing computational relationships between at least one bioinformatics data file and at least two bioinformatics programs. The workflow contains a dynamic set of predicates specific to the request based upon initial input data, general request parameters and the knowledge structure. The workflow is initiated based on a first predicate of the dynamic set of predicates and after a new unprocessed input data is obtained, the dynamic set of predicates is updated. The workflow continues until no more predicates can be associated with the unprocessed input data or no more unprocessed data can be obtained.
摘要:
Processes and systems for facilitating communications in a health care environment are provided. In one example, a process includes receiving a trigger from a wearable computer device to communicate with a medical application interface. The trigger may include detecting a hand gesture of a user of a wearable computer device (e.g., via a camera device or motion sensing device associated with the wearable computer device). The process may then display information associated with the medical application interface on the wearable computer device, and receive input from a user via the wearable computer device for interacting with the medical application interface. Displayed information may include patient information, medical records, test results, and so on. Further, a user may initiate and communicate with a remote user, the communication synchronizing information between two or more users (e.g., to synchronously view medical records, medical image files, and so on).
摘要:
The present technology is directed to apparatuses, machines and methods for determining the level of expression of creatine kinase enzyme in cancerous tissues, as well as for determining malignancy and providing a cancer prognosis. The method is based on overexpression of creatine kinase in cancer tissue and enhanced transformation of injected phosphocreatine substrate into creatine as detectable by NMR.
摘要:
Processes and systems for monitoring hand hygiene events (e.g., hand washing or sanitizing) are provided. In one example, a process includes receiving data associated with the initiation and completion of a hand hygiene event. The data may include image data captured by a camera included with a wearable computer device (e.g., a head mounted device or augmented reality glasses). The process may further determine a location and/or time associated with the initiation and completion of the hand hygiene event and monitor compliance and technique. A process may further include detecting a location (e.g., via a proximity beacon) of a wearable computer device and triggering a notification to initiate a hand hygiene event. Additionally, data from hand hygiene events, including compliance data, can be used to motivate or incentivize individuals to increase their compliance with hand hygiene practices (e.g., through various gamification strategies).
摘要:
The present disclosure relates to magnetic resonance imaging (MRI) methods comprising (i) obtaining a baseline chemical exchange saturation transfer (CEST) MRI image of a patient, (ii) administering an effective amount of a non-nutritive sweetener to the patient, and (iii) obtaining one or more test CEST MRI image of the patient subsequent to the administering step (ii); wherein the step (i) and (iii) acquisition parameters are substantially the same. The non- nutritive sweetener may include a natural or artificial sugar alcohol, polyol, or combinations or derivatives thereof.
摘要:
The present disclosure provides DPP-4 inhibitors for use in treating a bone fracture, for use in preventing non-union of a bone fracture or preventing healing complications following bone fracture, for use in reducing the inhibitory effects of marrow adipose tissue (MAT) on fracture healing, or for use in preventing loss of bone mineral density (BMD) in a subject in need thereof. The disclosure also provides methods of preparing cells for transplantation comprising providing a cell culture comprising osteogenic progenitor cells (OPCs) and/or mesenchymal stem cells, and contacting the cells with a DPP-4 inhibitor. The disclosure further provides methods of preparing cells for transplantation comprising providing a cell culture comprising CD45-CD31 - Sca1 + CD24 + multipotent cells, and treating the cell culture to promote lineage commitment and/or differentiation into osteogenic progenitor cells (OPCs) and/or mature cells of the osteogenic lineage/bone tissues.