公开(公告)号：WO02056945A8

公开(公告)日：2002-10-03

申请号：PCT/US0201657

申请日：2002-01-18

Applicant: MEDRAD INC ,  SPOHN MICHAEL A ,  DEDIG JAMES ALBERT ,  BERRY DAVID H ,  WILLIAMS GLEN P

Inventor： SPOHN MICHAEL A ,  DEDIG JAMES ALBERT ,  BERRY DAVID H ,  WILLIAMS GLEN P

IPC: A61M5/145 ,  A61M5/00

CPC classification number: A61M5/1458 ,  A61M5/14546 ,  A61M5/14566

Abstract: A syringe interface or adapter includes a first retaining member that pivots about an axis generally perpendicular to and offset from the axis of an injector piston when the syringe interface is attached to the injector. The first retaining member pivots in a rearward direction to engage a portion of the syringe flange. The syringe interface further includes a second retaining member slideably positioned within a passage in the syringe interface to slide in a direction generally perpendicular to the axis of the piston when the syringe interface is attached to the injector to engage a portion of the syringe flange. The first retaining member and the second retaining member preferably cooperate to engage the syringe flange around the entire perimeter of the syringe flange. The first retaining member is preferably biased toward an open position. The syringe interface can also include a rear portion having an attachment mechanism to attach the syringe interface to the injector.

Abstract translation: 注射器接口或适配器包括第一保持构件，当注射器接口附接到注射器时，第一保持构件围绕大致垂直于和从注射器活塞的轴线偏移的轴线枢转。 第一保持构件沿向后方向枢转以接合注射器凸缘的一部分。 注射器接口还包括第二保持构件，其可滑动地定位在注射器接口中的通道内，以便当注射器接口附接到注射器以与注射器凸缘的一部分接合时，大致垂直于活塞轴线的方向滑动。 第一保持构件和第二保持构件优选地配合以将注射器凸缘接合在注射器凸缘的整个周边周围。 第一保持构件优选地朝向打开位置偏置。 注射器接口还可以包括具有附接机构以将注射器接口附接到注射器的后部。

公开(公告)号：WO2007002154A3

公开(公告)日：2007-04-05

申请号：PCT/US2006024081

申请日：2006-06-21

Applicant: MEDRAD INC ,  GRIFFITHS DAVID M ,  ALMON-MARTIN ROSEMARY ,  HIRSCHMAN ALAN D ,  REILLY DAVID M ,  TROCKI MARK ,  TROMBLEY FREDERICK W ,  WEICH THOMAS R ,  JAECKLEIN WILLIAM J ,  SPOHN MICHAEL A ,  JOYCE THOMAS P

Inventor： GRIFFITHS DAVID M ,  ALMON-MARTIN ROSEMARY ,  HIRSCHMAN ALAN D ,  REILLY DAVID M ,  TROCKI MARK ,  TROMBLEY FREDERICK W ,  WEICH THOMAS R ,  JAECKLEIN WILLIAM J ,  SPOHN MICHAEL A ,  JOYCE THOMAS P

IPC: A61M31/00

CPC classification number: A61M25/10184 ,  A61M5/007 ,  A61M5/14566 ,  A61M5/16827 ,  A61M5/16854 ,  A61M25/007 ,  A61M25/104 ,  A61M2025/102 ,  A61M2025/1022

Abstract: A combined fluid injection and inflation system is disclosed and includes a fluid delivery system including at least one pressurizing device, a fluid path, and a control unit. The fluid path is adapted to connect the pressurizing device to a patient via a catheter including a balloon and inserted in the patient. The control unit is operable to control the fluid delivery system. In operation, the control unit selectively actuates the fluid delivery system to operate in a fluid injection mode or in a balloon inflation mode. In the fluid injection mode the pressurizing device delivers fluid to the fluid path for a fluid injection procedure. In the balloon inflation mode, the pressurizing device delivers fluid to the fluid path for inflating the balloon associated with the catheter. An operator control may be connected to the control unit for controlling the fluid delivery system and may be a handheld device.

Abstract translation: 公开了组合的流体注入和充气系统，并且包括包括至少一个加压装置，流体路径和控制单元的流体递送系统。 流体路径适于经由包括球囊并且插入患者体内的导管将加压装置连接到患者。 控制单元可操作以控制流体输送系统。 在操作中，控制单元选择性地致动流体输送系统以流体注射模式或气球充气模式操作。 在流体注射模式中，加压装置将流体输送到流体路径用于流体注射程序。 在球囊膨胀模式中，加压装置将流体输送到流体路径，用于使与导管相关联的球囊膨胀。 操作员控制可以连接到控制单元以控制流体输送系统，并且可以是手持装置。

公开(公告)号：WO2005097252A3

公开(公告)日：2005-12-29

申请号：PCT/US2005011560

申请日：2005-04-05

Applicant: MEDRAD INC ,  SCHRIVER RALPH H ,  SPOHN MICHAEL A ,  JOYCE THOMAS P ,  GRUBIC HERBERT M ,  CRITCHLOW RICHARD G

Inventor： SCHRIVER RALPH H ,  SPOHN MICHAEL A ,  JOYCE THOMAS P ,  GRUBIC HERBERT M ,  CRITCHLOW RICHARD G

IPC: A61M1/00 ,  A61M5/00 ,  A61M5/145 ,  A61M5/20 ,  A61M25/00 ,  A61M37/00

CPC classification number: A61M5/14546 ,  A61M5/007 ,  A61M5/14566 ,  A61M5/1458 ,  A61M2205/14 ,  A61M2205/587

Abstract: The fluid injection apparatus (10) is adapted for use with a syringe (24) and includes an injector (12) and a pressure jacket (32) associated with the injector (12). The injector (12) includes a housing defining an opening for a drive piston (22) extendable from the housing. The pressure jacket secures the syringe (24) during an injection (12) procedure. The pressure jacket (32) has a distal end defining a syringe (24) receiving opening for receiving the syringe (24), and a proximal end associated with the housing and generally aligned with the opening. The apparatus includes a syringe sensor adapted for engagement by the syringe when loaded into the pressure jacket (32). The housing may have an engagement tab adapted to engage an engagement recess in the pressure jacket (32) to removably engage the pressure jacket (32) with the housing.

Abstract translation: 流体注射装置（10）适于与注射器（24）一起使用，并且包括与注射器（12）相关联的注射器（12）和压力套（32）。 注射器（12）包括限定用于可从壳体延伸的驱动活塞（22）的开口的壳体。 在注射（12）程序期间，压力护套固定注射器（24）。 压力套（32）具有限定用于接收注射器（24）的注射器（24）接收开口的远端，以及与壳体相关联并且与开口大致对准的近端。 该装置包括适于在装入压力套（32）时由注射器接合的注射器传感器。 壳体可以具有适于接合压力套（32）中的接合凹部以将压力套（32）与壳体可拆卸地接合的接合突片。

公开(公告)号：WO2009051995A1

公开(公告)日：2009-04-23

申请号：PCT/US2008/079160

申请日：2008-10-08

Applicant: MEDRAD, INC. ,  JOYCE, Thomas, P. ,  SPOHN, Michael, A.

Inventor： JOYCE, Thomas, P. ,  SPOHN, Michael, A.

IPC: A61M31/00 ,  A61M37/00

CPC classification number: A61M5/14212 ,  A61M5/1452 ,  A61M5/14566 ,  A61M2005/14208 ,  A61M2205/3362

Abstract: A method of capacitance volume correction in fluid-containing expandable bodies and associated fluid pathways is disclosed for application in fluid delivery systems used to supply fluids to patients during radiographic imaging procedures including angiography. One embodiment is directed to a method of controlling delivery of fluid to a downstream process, including providing a fluid-containing expandable body, including a pressurizing element and in fluid communication with the downstream process, pressurizing the expandable body by moving the pressurizing element forward in the expandable body to reduce volume therein, and ceasing movement of the pressurizing element after allowing the pressurizing element to over-travel a sufficient distance to compensate for expansion of the expandable body under pressure. The expandable body may be a syringe and the pressurizing element may be a plunger disposed within the syringe. Movement of the pressurizing element is controlled by an algoπthm associated with a computer.

Abstract translation: 公开了一种用于含流体的可膨胀体和相关流体通路中的电容体积校正的方法，用于在用于在包括血管造影的放射照相成像程序期间向患者供应流体的流体输送系统中。 一个实施例涉及一种控制流体向下游过程输送的方法，包括提供含流体的可膨胀体，包括加压元件并且与下游流体流体连通，通过将加压元件向前移动来对可膨胀体进行加压 所述可膨胀体减小其中的体积，并且在允许加压元件过度行进足够的距离之后停止加压元件的运动，以补偿在膨胀的主体在压力下的膨胀。 可膨胀体可以是注射器，并且加压元件可以是设置在注射器内的柱塞。 加压元件的移动由与计算机相关联的算术控制。

公开(公告)号：WO2005105196A2

公开(公告)日：2005-11-10

申请号：PCT/US2005/011681

申请日：2005-04-05

Applicant: MEDRAD, INC. ,  SPOHN, Michael, A. ,  HAURY, John, A. ,  DEDIG, James Albert ,  FELIX, Susan Lynn ,  MCCOPPIN, Anthony, S. ,  EHRENBERGER, Michael, J. ,  GIMBEL, James, M. ,  SUNDAY, Jared, A.

Inventor： SPOHN, Michael, A. ,  HAURY, John, A. ,  DEDIG, James Albert ,  FELIX, Susan Lynn ,  MCCOPPIN, Anthony, S. ,  EHRENBERGER, Michael, J. ,  GIMBEL, James, M. ,  SUNDAY, Jared, A.

IPC: A61M25/16

CPC classification number: A61M39/24 ,  A61M5/007 ,  A61M5/1408 ,  A61M5/14546 ,  A61M5/16831 ,  A61M5/1684 ,  A61M5/16881 ,  A61M5/365 ,  A61M2005/1403 ,  A61M2005/14553 ,  A61M2039/242 ,  A61M2039/2473 ,  A61M2039/2486 ,  A61M2039/2493 ,  A61M2205/3306 ,  A61M2205/581 ,  A61M2205/583

Abstract: The fluid path set is intended for use in a fluid delivery system. The fluid path set includes a multi-patient use section adapted for connection to a pressurizing device used in the fluid delivery system, and to a source of fluid, such as contrast media, to be loaded into the syringe. The fluid path set further includes a per-patient use section that is removably connected to the multi-patient use section. One or more connectors removably connects the multi-patient use section and the per-patient use section. A drip chamber is provided between the source of fluid and the syringe, and includes a projection window for determining fluid levels in the drip chamber. The per-patient use section includes a pressure isolation mechanism. The pressure isolation mechanism includes a lumen, a pressure isolation port, and a valve member with a biasing portion that biases the valve member to a normally open position.

Abstract translation: 流体路径组用于流体输送系统。 流体路径组包括适于连接到在流体输送系统中使用的加压装置的多用户使用部分，以及要装载到注射器中的流体源（例如造影剂）。 流体路径组还包括可拆卸地连接到多用户使用部分的每个患者使用部分。 一个或多个连接器可拆卸地连接多用户使用部分和每个患者使用部分。 在流体源和注射器之间提供滴水室，并且包括用于确定滴液室中的液体水平的投影窗口。 患者使用部分包括压力隔离机构。 压力隔离机构包括管腔，压力隔离端口和具有将阀构件偏压到常开位置的偏置部分的阀构件。

公开(公告)号：WO2005104687A2

公开(公告)日：2005-11-10

申请号：PCT/US2005012562

申请日：2005-04-14

Applicant: MEDRAD INC ,  SPOHN MICHAEL A ,  JOYCE THOMAS P ,  EHRENBERGER MICHAEL J ,  DEDIG JAMES A ,  HAURY JOHN A ,  FELIX SUSAN L ,  CALLAN GERALD W ,  SHEARER JOHN D JR ,  SPEICHER JONATHAN R ,  SCUTT CHRISTOPHER M ,  GRUBIC HERB ,  KOPACKO RALPH ,  BARLOW WILLIAM D ,  STOKES JERRY A JR ,  CRITCHLOW RICHARD G ,  ZELENSKI KAREN M ,  HUSSAIN MIRZA H ,  O'MEARA LINDA M ,  BEAULIEU RODERICK H ,  KWO JENNIE ,  PEDRAZA LUIS A

Inventor： SPOHN MICHAEL A ,  JOYCE THOMAS P ,  EHRENBERGER MICHAEL J ,  DEDIG JAMES A ,  HAURY JOHN A ,  FELIX SUSAN L ,  CALLAN GERALD W ,  SHEARER JOHN D JR ,  SPEICHER JONATHAN R ,  SCUTT CHRISTOPHER M ,  GRUBIC HERB ,  KOPACKO RALPH ,  BARLOW WILLIAM D ,  STOKES JERRY A JR ,  CRITCHLOW RICHARD G ,  ZELENSKI KAREN M ,  HUSSAIN MIRZA H ,  O'MEARA LINDA M ,  BEAULIEU RODERICK H ,  KWO JENNIE ,  PEDRAZA LUIS A

IPC: A61G7/05 ,  A61M5/00 ,  A61M5/14 ,  A61M5/142 ,  A61M5/168 ,  A61M5/36 ,  A61M39/10 ,  F16M11/00

CPC classification number: A61M39/10 ,  A61G7/0503 ,  A61M5/007 ,  A61M5/1413 ,  A61M5/142 ,  A61M5/14228 ,  A61M5/1424 ,  A61M5/16881 ,  A61M5/31 ,  A61M5/36 ,  A61M2005/1402 ,  A61M2005/14553 ,  A61M2005/3128 ,  A61M2039/0009 ,  A61M2039/1033 ,  A61M2205/11

Abstract: The fluid delivery system generally includes a source of injection fluid, a pump device a fluid path set disposed between the source of injection fluid and the pump device, and a fluid control device. The fluid path set includes a multi-position valve. The fluid control device is operatively associated with the fluid path set and includes a valve actuator adapted to operate the multi-position valve. The valve actuator is adapted to close the multi-position valve to isolate the pump device from a patient and stop flow of the injection fluid to the patient at substantially any pressure or flow rate generated by the pump device for delivering a sharp bolus of the injection fluid to the patient. The valve actuator is generally adapted to selectively place the pump device in fluid communication with the source of injection fluid for supplying the injection fluid to the pump device and the patient.

Abstract translation: 流体输送系统通常包括注射流体源，泵装置，设置在注射流体源和泵装置之间的流体路径组和流体控制装置。 流体路径组包括多位置阀。 流体控制装置与流体路径组合操作地相关联并且包括适于操作多位置阀的阀致动器。 阀致动器适于关闭多位置阀，以将泵装置与患者隔离，并以基本上由泵装置产生的任何压力或流速停止注射流体到达患者的流动，用于递送喷射的尖锐推注 流体到患者。 阀致动器通常适于选择性地将泵装置与注射流体源流体连通，以将注射流体供应到泵装置和患者。

公开(公告)号：WO2005097252A2

公开(公告)日：2005-10-20

申请号：PCT/US2005/011560

申请日：2005-04-05

Applicant: MEDRAD, INC. ,  SCHRIVER, Ralph, H. ,  SPOHN, Michael, A. ,  JOYCE, Thomas, P. ,  GRUBIC, Herbert, M. ,  CRITCHLOW, Richard, G.

Inventor： SCHRIVER, Ralph, H. ,  SPOHN, Michael, A. ,  JOYCE, Thomas, P. ,  GRUBIC, Herbert, M. ,  CRITCHLOW, Richard, G.

IPC: A61M37/00

CPC classification number: A61M5/14546 ,  A61M5/007 ,  A61M5/14566 ,  A61M5/1458 ,  A61M2205/14 ,  A61M2205/587

Abstract: The fluid injection apparatus is adapted for use with a syringe and includes an injector and a pressure jacket associated with the injector. The injector includes a housing defining an opening for a drive piston extendable from the housing. The pressure jacket secures the syringe during an injection procedure. The pressure jacket has a distal end defining a syringe receiving opening for receiving the syringe, and a proximal end associated with the housing and generally aligned with the opening. The apparatus includes a syringe sensor adapted for engagement by the syringe when loaded into the pressure jacket. The housing may have an engagement tab adapted to engage an engagement recess in the pressure jacket to removably engage the pressure jacket with the housing. The apparatus may have one or more light sources associated with the housing for illuminating the syringe received in the pressure jacket.

Abstract translation: 流体注射装置适于与注射器一起使用，并且包括与注射器相关联的注射器和压力护套。 注射器包括限定用于可从壳体延伸的驱动活塞的开口的壳体。 压力套管在注射过程中固定注射器。 压力护套具有限定用于接收注射器的注射器接收开口的远端，以及与壳体相关联并且与开口大致对准的近端。 该装置包括一个注射器传感器，适用于在装入压力套时由注射器接合。 壳体可以具有适于接合压力套中的接合凹部的接合突片，以将压力套与壳体可拆卸地接合。 该装置可以具有与壳体相关联的一个或多个光源，用于照射在压力套中接收的注射器。

公开(公告)号：WO2007002154A2

公开(公告)日：2007-01-04

申请号：PCT/US2006/024081

申请日：2006-06-21

Applicant: MEDRAD, INC. ,  GRIFFITHS, David, M. ,  ALMON-MARTIN, Rosemary ,  HIRSCHMAN, Alan, D. ,  REILLY, David, M. ,  TROCKI, Mark ,  TROMBLEY, Frederick, W. ,  WEICH, Thomas, R. ,  JAECKLEIN, William, J. ,  SPOHN, Michael, A. ,  JOYCE, Thomas, P.

Inventor： GRIFFITHS, David, M. ,  ALMON-MARTIN, Rosemary ,  HIRSCHMAN, Alan, D. ,  REILLY, David, M. ,  TROCKI, Mark ,  TROMBLEY, Frederick, W. ,  WEICH, Thomas, R. ,  JAECKLEIN, William, J. ,  SPOHN, Michael, A. ,  JOYCE, Thomas, P.

IPC: A61M29/00

CPC classification number: A61M25/10184 ,  A61M5/007 ,  A61M5/14566 ,  A61M5/16827 ,  A61M5/16854 ,  A61M25/007 ,  A61M25/104 ,  A61M2025/102 ,  A61M2025/1022

Abstract: A combined fluid injection and inflation system is disclosed and includes a fluid delivery system including at least one pressurizing device, a fluid path, and a control unit. The fluid path is adapted to connect the pressurizing device to a patient via a catheter including a balloon and inserted in the patient. The control unit is operable to control the fluid delivery system. In operation, the control unit selectively actuates the fluid delivery system to operate in a fluid injection mode or in a balloon inflation mode. In the fluid injection mode the pressurizing device delivers fluid to the fluid path for a fluid injection procedure. In the balloon inflation mode, the pressurizing device delivers fluid to the fluid path for inflating the balloon associated with the catheter. An operator control may be connected to the control unit for controlling the fluid delivery system and may be a handheld device.

Abstract translation: 公开了一种组合的流体注射和充气系统，其包括流体输送系统，该流体输送系统包括至少一个加压装置，流体路径和控制单元。 流体路径适于经由包括气囊的导管将加压装置连接至患者，并插入患者体内。 控制单元可操作以控制流体输送系统。 在操作中，控制单元选择性地致动流体输送系统以流体注射模式或气囊充气模式操作。 在流体注入模式中，加压装置将流体输送到流体路径以进行流体注入程序。 在球囊充气模式中，加压装置将流体输送到流体路径以使与导管相关联的球囊膨胀。 操作员控制器可以连接到控制单元以控制流体输送系统，并且可以是手持设备。

公开(公告)号：WO02056945A3

公开(公告)日：2002-12-12

申请号：PCT/US0201657

申请日：2002-01-18

Applicant: MEDRAD INC ,  SPOHN MICHAEL A ,  DEDIG JAMES ALBERT ,  BERRY DAVID H ,  WILLIAMS GLEN P

Inventor： SPOHN MICHAEL A ,  DEDIG JAMES ALBERT ,  BERRY DAVID H ,  WILLIAMS GLEN P

IPC: A61M5/145

CPC classification number: A61M5/1458 ,  A61M5/14546 ,  A61M5/14566

Abstract: A syringe interface or adapter (700) includes a first retaining member (730) that pivots about an axis generally perpendicular to and offset from the axis (A") of an injector piston when the syringe interface is attached to the injector. The first retaining member (720) pivots in a rearward direction to engage a portion of the syringe flange (220). The syringe interface further includes a second retaining member slideably positioned within a passage in the syringe interface to slide in a direction generally perpendicular to the axis of the piston when the syringe interface is attached to the injector to engage a portion of the syringe flange. The first retaining member and the second retaining member preferably cooperate to engage the syringe flange around the entire perimeter of the syringe flange. The first retaining member is preferably biased toward an open position. The syringe interface can also include a rear portion having an attachment mechanism to attach the syringe interface to the injector.

Abstract translation: 注射器接口或适配器（700）包括第一保持构件（730），当第一保持构件（730）附接到注射器时，第一保持构件（730）绕着大致垂直于和从该注射器活塞的轴线（A“）偏移的轴线枢转， 所述注射器接口还包括可滑动地定位在所述注射器接口中的通道内的第二保持构件，以沿着大致垂直于所述注射器凸缘的轴线的方向滑动 当所述注射器接口附接到所述注射器以接合所述注射器凸缘的一部分时，所述活塞优选地配合以使所述注射器凸缘接合所述注射器凸缘的整个周边，所述第一保持构件 优选地朝向打开位置偏压。注射器接口还可以包括具有附接机构以附接注射器接口的后部 到注射器。

公开(公告)号：WO2012155035A1

公开(公告)日：2012-11-15

申请号：PCT/US2012/037491

申请日：2012-05-11

Applicant: MEDRAD, INC. ,  SHEARER, John, D., Jr ,  SCUTT, Christopher, M. ,  GRUMSKI, Walter, J. ,  SPOHN, Michael, A. ,  MCWILLIAMS, Jarrell, T. ,  LONG, Arlie, D. ,  MORTON, Richard, C.

Inventor： SHEARER, John, D., Jr ,  SCUTT, Christopher, M. ,  GRUMSKI, Walter, J. ,  SPOHN, Michael, A. ,  MCWILLIAMS, Jarrell, T. ,  LONG, Arlie, D. ,  MORTON, Richard, C.

IPC: A61M1/00

CPC classification number: A61M5/16831 ,  A61M5/00 ,  A61M5/007 ,  A61M5/14546 ,  A61M2005/14553 ,  A61M2205/215 ,  A61M2205/50 ,  A61M2205/502

Abstract: A fluid injection system that includes an injector head having a syringe for delivering a fluid to a patient; a mounting structure pivotally connected to the injector head and configured to support the injector head above a surface; and a control system operationally coupled to the injector head for controlling an injection procedure is disclosed. The fluid injection system is provided with various sensors to control various aspects of the fluid injection system, such as the establishment of a reference plane, the determination of a tilt angle of the injector head, and the determination of a temperature of an actuation system of the injector head.

Abstract translation: 一种流体注射系统，其包括具有用于将流体输送给患者的注射器的注射器头部; 安装结构，其枢转地连接到所述注射器头部并且构造成将所述注射器头部支撑在表面上方; 并且公开了一种可操作地耦合到喷射头的用于控制喷射程序的控制系统。 流体注射系统设置有各种传感器以控制流体喷射系统的各个方面，例如建立参考平面，确定喷射器头部的倾斜角度以及确定致动系统的温度 注射头。