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公开(公告)号:WO2023091313A2
公开(公告)日:2023-05-25
申请号:PCT/US2022/048935
申请日:2022-11-04
Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY
Inventor: MASTRO, Michael, A. , GALLAGHER, James , ANDERSON, Travis, J.
IPC: G01N21/95 , G01N21/88 , G01N23/2251 , G01N23/20 , G01R31/26 , G06N3/0442 , G06N3/0464 , H01L21/66
Abstract: A computer-implemented method for evaluating a semiconductor wafer. In accordance with the present invention, using a properly designed neural network, the computer can take image data regarding the wafer at issue, plus image and electrical data regarding a prior wafer and devices fabricated on the prior wafer, to find relations to and between structural features, both known and previously unidentified, that can degrade the performance of devices fabricated on the wafer and/or can reduce the device yield of the wafer.
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公开(公告)号:WO2023009203A1
公开(公告)日:2023-02-02
申请号:PCT/US2022/031019
申请日:2022-05-26
Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY
Inventor: CHRISTOPHERSEN, Marc , PHILIPS, Bernard, F.
Abstract: A conformally metal-coated glass capillary array and method of fabricating same. A glass capillary array is provided. The glass capillary array includes a plurality of glass capillaries, The glass capi llary array includes a plurality of glass capillary array walls. The plurality of glass capillary array walls define a plurality of holes. The plurality of holes includes a plurality of hole peripheries. An electroless metallization catalyst is provided around the plurality of hole peripheries. A first metal is electroless plated on the plurality of glass capillary array walls using the electroless metallization catalyst. A second metal is electroplated on the electroless-plated, first metal, or the second metal is electroless-plated on the electroless-plated, first metal.
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公开(公告)号:WO2022094009A1
公开(公告)日:2022-05-05
申请号:PCT/US2021/056938
申请日:2021-10-28
Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY
Inventor: GOLDMAN, Ellen, R. , ANDERSON, George, P. , LIU, Jinny, L. , ESPARZA, Thomas, J.
IPC: C07K16/10 , G01N33/569
Abstract: A number of single domain antibodies (sdAb, also known as nanobodies or VHH) were developed that bind nucleocapsid protein of the SARS-CoV-2 virus. They are useful for detecting the virus and could also find application in therapeutics.
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公开(公告)号:WO2021216941A2
公开(公告)日:2021-10-28
申请号:PCT/US2021/028746
申请日:2021-04-23
Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY
Inventor: BOERCKER, Janice, E. , BRITTMAN, Sarah, F. , TISCHLER, Joseph, G. , YEE, Patrick, Y. , ELLIS, Chase, T. , CUNNINGHAM, Paul, D. , STROUD, Rhonda, M. , STEWART, Michael, H. , ERWIN, Steven, C.
Abstract: A process for synthesizing Cu2-xS/PbS core/shell nanocrystals. Pb-oleate is mixed with 1-octadecene and heated to 60 °C. Cu2-xS core solution and bis(trimethylsilyl)sulfide stock solution are added and the mixture is stirred at 60 °C for 6 minutes to form the PbS shell around the Cu2-xS nanocrystal cores. The flask is cooled and acetonitrile and toluene is added and the mixture is centrifuged to precipitate and remove the Cu2-xS/PbS core/shell nanocrystals from the reaction mixture. The reaction also produces homogeneously nucleated PbS nanocrystals, which are removed from the Cu2-xS/PbS core/shell reaction mixture via size-selective precipitation. By tailoring the amounts of Pb-oleate and bis(trimethylsilyl)sulfide stock solution in the reaction vessel, while maintaining their molar ratio of 1.5:1 and the number of Cu2-xS cores in the reaction, Cu2-xS/PbS core/shell nanocrystals having a predetermined shell thickness of PbS, and thus a predetermined level of chemical stability, can be obtained.
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公开(公告)号:WO2021188818A1
公开(公告)日:2021-09-23
申请号:PCT/US2021/023002
申请日:2021-03-18
Inventor: BISWAS, Biswajit , BISHOP-LILLY, Kimberly
Abstract: The invention relates to a method of preventing, ameliorating or treating disease caused by coronavirus in a subject in need thereof comprising administering to the subject an immunogenic composition comprising a therapeutically effective amount of one or more bacteriophage displaying on its capsid one or more antigenic coronavirus peptides fused with one or more bacteriophage capsid proteins (PVPs).
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公开(公告)号:WO2021168039A1
公开(公告)日:2021-08-26
申请号:PCT/US2021/018460
申请日:2021-02-18
Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY , THE CHARLES STARK DRAPER LABORATORY, INC.
Inventor: GLAVEN, Sarah , ONDERKO, Elizabeth , MAYGAR, Andrew , YATES, Matthew
Abstract: Described herein are biofilm bioreactors for synthesis at the interface between two liquids, and methods of using such bioreactors for the biotransformation of feedstocks into chemical products. Also contemplated is the extraction of such products.
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公开(公告)号:WO2021113510A1
公开(公告)日:2021-06-10
申请号:PCT/US2020/063107
申请日:2020-12-03
Applicant: THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE , THE GOVERNMENT OF THE UNITED STATES, as represented by THE SECRETARY OF THE ARMY , THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY
Inventor: BRADLEY, Matthew, J. , ELSTER, Eric, A. , KHATRI, Vivek , OH, John, S. , SCHOBEL, Seth, A.
Abstract: The present disclosure describes methods and systems for predicting if a subject has an increased risk of having or developing venous thromboembolism, including prior to the detection of symptoms thereof and/or prior to onset of any detectable symptoms thereof. The present disclosure also describes a method of generating a model for predicting venous thromboembolism.
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公开(公告)号:WO2021113458A1
公开(公告)日:2021-06-10
申请号:PCT/US2020/063034
申请日:2020-12-03
Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY
Inventor: BOYD, Darryl, A. , MYERS, Jason, D. , NGUYEN, Vinh, Q. , GIBSON, Daniel, J. , BAKER, Colin, C. , KIM, Woohong , SANGHERA, Jasbinder, S.
Abstract: A method for bonding infrared transparent materials by placing a polymer comprising at least one chalcogenide element and crosslinking moieties between infrared-transparent optical elements and applying heat, pressure, or both. The crosslinking moieties may be organic, inorganic, or both. Also disclosed is the related bonded assembly comprising infrared transparent optical elements.
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公开(公告)号:WO2021080697A1
公开(公告)日:2021-04-29
申请号:PCT/US2020/049800
申请日:2020-09-09
Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY
Inventor: SIMPKINS, Blake , DUNKELBERGER, Adam , OWRUTSKY, Jeffrey C. , SHAW, L. Brandon , FEARS, Kenan P. , PIETRON, Jeremy J.
IPC: H04B10/516 , H01S3/11 , H01S3/10 , H01S3/08
Abstract: An apparatus including an optical resonator, and a method of using same. The optical limiter includes an optically absorbent material. The optical resonator supports a plurality of resonant transmission peaks at resonant frequencies defined by the cavity length. The optically absorbent material exhibits a saturable absorption response at a fundamental absorption peak located spectrally at a fundamental absorption peak frequency of the plurality of resonant transmission peaks. The optically absorbent material includes an absorptivity sufficient for strong cavity coupling, such that the fundamental absorption peak splits into a first upper vibration polariton transmission peak and a second lower polariton transmission peak separated by a Rabi splitting. The Rabi splitting is proportional to a square root of the absorptivity. The absorptivity varies with optical excitation of the optically absorbent: material. The absorptivity is maximized at a photon-unsaturated ground state, and the absorptivity is minimized at an optically excited state.
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公开(公告)号:WO2021034873A2
公开(公告)日:2021-02-25
申请号:PCT/US2020/046880
申请日:2020-08-19
Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY
Inventor: GATTASS, Rafael, R. , BAKER, Colin, C. , CARLSON, Augustus, Xavier , SHAW, Brandon, L. , JASBINDER, Sanghera, S.
Abstract: An apparatus includes an amplified spontaneous emission source, which in turn includes an optical fiber. The optical, fiber includes a solid core and a first end. The solid core includes a silica matrix. The silica matrix includes a rare-earth element and a glass co-dopant. The rate-earth element includes dysprosium or neodymium. The glass co-dopant includes AI2O3. The apparatus further includes a laser pump diode coupled to the first end of the optical fiber. The laser pump diode and the optical fiber cooperate to generate a spontaneous spectral emission confined to the solid core. The spontaneous spectral emission includes a simultaneous plurality of spectral regions.
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