PROCEDIMIENTO, PROGRAMA INFORMÁTICO, SISTEMA Y SISTEMA INFORMÁTICO PARA ELIMINACIÓN DE RUIDO EN UNA SECUENCIA DE IMÁGENES

    公开(公告)号:WO2021229129A1

    公开(公告)日:2021-11-18

    申请号:PCT/ES2021/070336

    申请日:2021-05-12

    Abstract: Se proporcionan procedimientos, programas y sistemas para eliminación de ruido en una secuencia de imágenes producida por un procedimiento de generación de imágenes con datos volumétricos utilizando un algoritmo de trazado de caminos de rayos de luz en medios participativos. Cada imagen de la secuencia comprende píxeles y el algoritmo de trazado de caminos produce muestras de camino para cada píxel. Estos procedimientos comprenden para cada píxel de una imagen actual de la secuencia: re-proyectar temporalmente el píxel dependiendo de un vector de movimiento para obtener un color promedio acumulado y un modelo predictivo del píxel; promediar un color del píxel con el color promedio acumulado para obtener un color promedio acumulado actualizado; incluir el color promedio acumulado actualizado en un vector de características; y determinar un color final del píxel actualizando el modelo predictivo dependiendo del vector de características actualizado y obteniendo dicho color final del modelo predictivo actualizado.

    METHOD FOR IN VITRO DIAGNOSIS OF DEMENTIA WITH LEWY BODIES USING ALPHASYNUCLEIN GENE TRANSCRIPTS
    4.
    发明申请
    METHOD FOR IN VITRO DIAGNOSIS OF DEMENTIA WITH LEWY BODIES USING ALPHASYNUCLEIN GENE TRANSCRIPTS 审中-公开
    使用碱性磷酸酶基因转录物进行体外诊断的方法

    公开(公告)号:WO2016180726A1

    公开(公告)日:2016-11-17

    申请号:PCT/EP2016/060177

    申请日:2016-05-06

    CPC classification number: C12Q1/6883 C12Q2600/106 C12Q2600/158

    Abstract: The present invention provides a method for the in vitro diagnosis of dementia with Lewy bodies in a human patient comprising the step of determining the amount of transcripts SNCAtv3 (SEQ ID NO: 3) and SNCAtv2 (SEQ ID NO: 2) of the human alpha-synuclein gene (SNCA) in a biological sample obtained from the patient, wherein when the amount of both transcripts determined for the patient is reduced with respect to a reference value, this is indicative of the presence of dementia with Lewy bodies in the patient. The invention further provides means to determine the amount of said transcripts, as well as a method to stablish the response of a patient which has been diagnosed with dementia with Lewy bodies to a medical regime for its treatment by determining the amount of transcripts SNCAtv3 and SNCAtv2 in a biological sample from the patient before and after the treatment.

    Abstract translation: 本发明提供了一种用于人类患者路易体痴呆体外诊断的方法,其包括测定人α的转录物SNCAtv3(SEQ ID NO:3)和SNCAtv2(SEQ ID NO:2)的量的步骤 - 来自患者的生物样品中的突触核蛋白基因(SNCA),其中当相对于参考值减少为患者确定的两个转录物的量减少时,这表明患者中路易体的痴呆的存在。 本发明还提供了确定所述转录物的量的方法,以及通过确定转录物量SNCAtv3和SNCAtv2来确定已被诊断患有路易体性痴呆的患者对其治疗的医疗方案的反应的方法 在患者治疗前后的生物样品中。

    DIAGNOSIS OF DEMENTIA WITH LEWY BODIES
    5.
    发明申请
    DIAGNOSIS OF DEMENTIA WITH LEWY BODIES 审中-公开
    诊断与虚弱的身体的DEMENTIA

    公开(公告)号:WO2016180725A1

    公开(公告)日:2016-11-17

    申请号:PCT/EP2016/060176

    申请日:2016-05-06

    CPC classification number: C12Q1/6883 C12Q2600/106 C12Q2600/112 C12Q2600/156

    Abstract: The invention provides an in vitro method for the diagnosis of dementia with Lewy bodies comprising detecting, in a biological sample from a subject, at least one variation in SEQ ID NO: 14, or alternatively at least one variation in SEQ ID NO: 15, or alternatively at least one variation in SEQ ID NO: 16, wherein SEQ ID NO: 14, SEQ ID NO: 15 and SEQ ID NO: 16 are comprised within position 175.989.261 to position 176.003.107 in Homo sapiens chromosome 5 according to HapMap data release 28 (SEQ ID NO: 1). The invention also provides means for detecting the above variations and a method for recommending to initiate a medical regime for the treatment of DLB in a subject based on detecting the above variations. In particular, the provided method is for the in vitro diagnosis of pure dementia with Lewy bodies.

    Abstract translation: 本发明提供了用于诊断路易体痴呆症的体外方法,包括在来自受试者的生物样品中检测SEQ ID NO:14中的至少一个变体,或者SEQ ID NO:14中至少一个变体, 或者可选地,SEQ ID NO:16中的至少一个变体,其中SEQ ID NO:14,SEQ ID NO:15和SEQ ID NO:16包含在位置175.989.261中,以在智人5号染色体中位置176.003.107根据 HapMap数据版本28(SEQ ID NO:1)。 本发明还提供了用于检测上述变化的方法以及用于基于检测上述变化来推荐用于开始用于治疗受试者的DLB的医疗方案的方法。 特别地,所提供的方法是用路易体纯体痴呆的体外诊断。

    METHOD FOR DETECTING DEFECTS ON YARNS
    7.
    发明申请
    METHOD FOR DETECTING DEFECTS ON YARNS 审中-公开
    检测缺陷的方法

    公开(公告)号:WO2012152336A1

    公开(公告)日:2012-11-15

    申请号:PCT/EP2011/057719

    申请日:2011-05-12

    Abstract: In a first aspect, the present invention provides a method for detecting defects on yarns arranged substantially in parallel from a grey scale image (10) of the yarns, said grey scale image being divided into one or more image sections; the method comprising for each image section (10): calculating a restrictive threshold and a less restrictive threshold from the image section (10); obtaining a restrictive image section (11) by applying the restrictive threshold to the image section (10); obtaining a less restrictive image section (12) by applying the less restrictive threshold to the image section (10). Said method further comprises: obtaining a differential image (13) from the obtained restrictive image sections (11) and the obtained less restrictive image sections (12); and detecting defects on the yarns by comparing (15) the pixels (16) of the differential image (13) representing existence of difference with predetermined defect patterns (14).

    Abstract translation: 在第一方面,本发明提供了一种用于检测从纱线的灰度图像(10)基本平行布置的纱线上的缺陷的方法,所述灰度图像被分成一个或多个图像部分; 所述方法包括对于每个图像部分(10):从所述图像部分(10)计算限制性阈值和较少限制性阈值; 通过对图像部分(10)应用限制性阈值来获得限制性图像部分(11); 通过对图像部分(10)应用较少限制的阈值来获得较少限制的图像部分(12)。 所述方法还包括:从获得的限制图像部分(11)和获得的较少限制的图像部分(12)获得差分图像(13); 并且通过将代表差异图像(13)的差分图像的像素(16)与预定缺陷图案(14)进行比较来检测纱线上的缺陷。

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