公开(公告)号：WO2022197778A1

公开(公告)日：2022-09-22

申请号：PCT/US2022/020513

申请日：2022-03-16

Applicant: THE UNIVERSITY OF AKRON ,  SWIMC LLC

Inventor： JOY, Abraham ,  NARAYANAN, Amal ,  KAUSHIK, Mishra ,  SAMARANAYAKE, Gamini ,  KOIS, Adam

IPC: C08F2/26 ,  C08F8/12 ,  C08F220/18 ,  C09D133/08 ,  C07F7/18

Abstract: A water-borne emulsion polymer that comprises one or more dihydroxyphenyl groups pendent to a linear or branched backbone of the polymer as well as structural groups derived from alkyl(meth)acrylate, styrene, (meth)acrylic acid, vinyl acetate, vinyl esters, hydroxyalkyl (meth)acrylate, or combinations thereof. Also disclosed are coating compositions that include the emulsion polymer and methods of making the water-borne emulsion polymer.

公开(公告)号：WO2022031895A1

公开(公告)日：2022-02-10

申请号：PCT/US2021/044616

申请日：2021-08-05

Applicant: THE UNIVERSITY OF AKRON ,  CAMBRIDGE ENTERPRISE LIMITED

Inventor： KENNEDY, Joseph ,  NUGAY, Turgut ,  NUGAY, Nihan ,  DEODHAR, Tejal ,  MOGGRIDGE, Geoff ,  PATEL, Ruhi

IPC: C08G18/40 ,  C08G18/62 ,  A61L27/18 ,  A61L27/34

Abstract: A method of preparing a polyisobutylene-based polyurethane for making heart valves is disclosed, wherein the method includes providing a polyisobutylene (PIB) polymer, freshly distilling a diisocyanate compound to create a freshly distilled diisocyanate and providing a chain extender. When the polyisobutylene polymer, the freshly distilled diisocyanate, and the chain extender are combined together by mixing, the created polyisobutylene-based polyurethane exhibits a higher number average molecular weight, a higher ultimate strength, a higher elongation, and a greater toughness than a polyisobutylene-based polyurethane made without a freshly distilled diisocyanate, which makes the polymer particularly useful as a bioprosthetic heart valve.

公开(公告)号：WO2022015989A1

公开(公告)日：2022-01-20

申请号：PCT/US2021/041837

申请日：2021-07-15

Applicant: THE UNIVERSITY OF AKRON ,  BECKER, Matthew ,  BASS, Garrett Frederic

Inventor： BECKER, Matthew ,  BASS, Garrett Frederic

IPC: A61K31/506 ,  A61K47/14

Abstract: In one or more embodiments, the present invention provides am method of making a poly(propylene fumarate-co-succinate) (PPFS) copolymer containing a random incorporation of succinate groups and targetable reduction profiles without the need for three or more monomer units. To achieve this, a time-dependent sonication-promoted zinc/acetic acid reduction of the PPM unsaturated double bonds has been used to create a random PPMS copolymer which may be isomerized into the PPFS equivalent. By changing the sonication time as well as the ratios of acetic acid, zinc, and PPM unsaturated alkenes, partial reduction of the PPM alkenes has been shown to give PPMS products containing varying compositions of succinic and maleate units, which may then be isomerized to the PPFS product.

公开(公告)号：WO2021163290A1

公开(公告)日：2021-08-19

申请号：PCT/US2021/017609

申请日：2021-02-11

Applicant: THE UNIVERSITY OF AKRON

Inventor： WONG, Shing-Chung Josh

IPC: B01D53/26 ,  B01D53/28 ,  F25D17/06

Abstract: A freshwater harvesting assembly includes a micro-scale component selected from a polymer, a foam, and a membrane; a water-sorption material selected from metal-organic framework (MOF), nanosilica gel, and superabsorbent polymer; wherein the water-sorption material is incorporated within the micro-scale component to thereby provide a water-sorption-material-containing micro-scale component; and a housing carrying the water-sorption-material-containing micro-scale component.

公开(公告)号：WO2020076788A1

公开(公告)日：2020-04-16

申请号：PCT/US2019/055142

申请日：2019-10-08

Applicant: TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC. ,  THE UNIVERSITY OF AKRON

Inventor： NAGAI, Tomoyuki ,  JIA, Hongfei ,  PENG, Zhengmeng ,  SHEN, Xiaochen ,  WU, Dezhen

IPC: H01M4/86 ,  H01M4/92 ,  H01M4/90 ,  H01M8/1018

Abstract: Oxygen reduction reaction (ORR) catalyst have particles of a first ORR catalytic material in interspersed contact with particles of a second ORR catalytic material. The first and second ORR catalytic materials have different d band centers so that oxygen can adsorb rapidly at a first binding site, be partly reduced, and then transfer to a second site at which reduction is completed and water desorption is rapid. This allows the catalyst to avoid limitations of slow reactant binding and/or slow product release.

公开(公告)号：WO2019032541A1

公开(公告)日：2019-02-14

申请号：PCT/US2018/045546

申请日：2018-08-07

Applicant: THE UNIVERSITY OF AKRON ,  BECKER, Matthew ,  PETERSON, Gregory Isaac ,  ABEL, Alexandra

Inventor： BECKER, Matthew ,  PETERSON, Gregory Isaac ,  ABEL, Alexandra

IPC: A61L27/18 ,  A61L27/58 ,  C08G71/02

Abstract: In one or more embodiments, the present invention provide a novel drug loaded amino acid based poly(ester urea) polymers for use in drug delivery having shape memory properties and without the shortcomings of the polymers for drug delivery known in the art, as well as related methods for their synthesis and use.

公开(公告)号：WO2018200640A1

公开(公告)日：2018-11-01

申请号：PCT/US2018/029307

申请日：2018-04-25

Applicant: THE UNIVERSITY OF AKRON

Inventor： CHASE, George ,  BANDEKAR, Ashish ,  GADHAVE, Ashish

IPC: B01D17/02 ,  B01D17/025 ,  B01D17/032 ,  B01D17/04 ,  B01D17/06 ,  B01D27/08 ,  C10G33/02

Abstract: An electrowetting coalescing device for coalescing droplets of a dispersed phase within a continuous phase includes an inlet in fluid communication with a first porous layer and a second porous layer. The first porous layer is employed as a first electrode and the second porous layer is employed as a second electrode, and a voltage difference exists between the first porous layer and the second porous layer to thereby create an electric field between the first porous layer and the second porous layer. The electrowetting coalescing device includes an outlet for receiving a fluid having passed through the first porous layer and the second porous layer.

公开(公告)号：WO2018144849A1

公开(公告)日：2018-08-09

申请号：PCT/US2018/016627

申请日：2018-02-02

Applicant: BECKER, Matthew ,  WILSON, Alexander ,  CHEN, Yusheng ,  THE UNIVERSITY OF AKRON

Inventor： BECKER, Matthew ,  WILSON, Alexander ,  CHEN, Yusheng

IPC: A61L27/18 ,  C08G63/52 ,  C08G63/78 ,  C08G63/90 ,  C08G63/91 ,  C08G63/676 ,  C08L63/10

Abstract: In one or more embodiments, the present invention is directed to poly(propylene fumarate) polymers and polymer structures made therefrom (and related methods) that have been end and/or monomer functionalized to add functional groups for post-polymerization modification with bioactive materials or other functional species, preferably through one of many facile "click" reactions. In some embodiments, end-group functionalization is accomplished via a functionalized initiating alcohol used during polymerization. In some embodiments, functionalization of these poly(propylene fumarate) polymers is accomplished via the functionalization of the propylene oxide monomer precursors, which then form functionalized side-chains on the resulting poly(propylene fumarate) polymers.

公开(公告)号：WO2017075370A2

公开(公告)日：2017-05-04

申请号：PCT/US2016/059350

申请日：2016-10-28

Applicant: THE UNIVERSITY OF AKRON ,  CHOI, Jae-Won ,  YUN, Yang H.

Inventor： CHOI, Jae-Won ,  YUN, Yang H.

IPC: B41J2/07 ,  B33Y30/00

CPC classification number: B33Y30/00 ,  B29C64/124 ,  B29C64/264 ,  B33Y10/00

Abstract: An additive printing apparatus includes a light transmissive substrate, a light source adapted to direct light through the light transmissive substrate, a photopolymerizable material source providing photopolymerizable material, and a fluid path from the photopolymerizable material source to a delivery position proximate the light transmissive substrate. Material is delivered through the fluid path the delivery position to form a liquid bridge of the photopolymerizable material, the liquid bridge having an area of contact with the light transmissive substrate, such that, in a method of additive printing, photopolymerizing light can be shone through the light transmissive substrate to polymerize the photopolymerizable material.

Abstract translation: 一种添加印刷设备包括透光衬底，适于引导光通过透光衬底的光源，提供可光聚合材料的可光聚合材料源以及从可光聚合材料源到 输送位置靠近透光衬底。 材料通过输送位置的流体路径输送，以形成可光聚合材料的液桥，液桥具有与透光基材接触的区域，使得在添加印刷的方法中，光聚合光可以透过 透光衬底聚合可光聚合材料。

公开(公告)号：WO2016133887A1

公开(公告)日：2016-08-25

申请号：PCT/US2016/018043

申请日：2016-02-16

Applicant: THE UNIVERSITY OF AKRON ,  BECKER, Matthew L. ,  ZANDER, Zachary K. ,  WADE, Mary E.

Inventor： BECKER, Matthew L. ,  ZANDER, Zachary K. ,  WADE, Mary E.

IPC: A61K9/52 ,  A61K47/42

CPC classification number: A61L15/40 ,  A61L15/26 ,  C08L71/02

Abstract: A wound dressing includes decellularized tissue and fibers at least partially surrounded by a PEG hydrogel, wherein the PEG hydrogel is structured by covalent bonds formed via an oxime ligation reaction of a polyethylene glycol (PEG) containing component and a cross-linking component. A method of making a hydrogel includes mixing a polyethylene glycol (PEG) component with a cross-linking component in a buffer solution, the PEG component having multiple arms with terminal functionality selected from ketone functionality and aldehyde functionality, and the cross-linking component having multiple arms with terminal aminooxy functionality, the hydrogel forming in the buffer solution by oxime ligation reaction, wherein the pH of the buffer solution used to make the hydrogel has a pH range of from 1.5 to 7.6, and the concentration of the buffer solution is from about 10 mM to about 100 mM

Abstract translation: 伤口敷料包括脱细胞组织和至少部分被PEG水凝胶包围的纤维，其中PEG水凝胶由通过含聚乙二醇（PEG）组分和交联组分的肟连接反应形成的共价键构成。 制备水凝胶的方法包括将聚乙二醇（PEG）组分与缓冲溶液中的交联组分混合，所述PEG组分具有多个臂，末端官能团选自酮官能团和醛官能团，并且所述交联组分具有 具有末端氨氧基官能团的多臂，通过肟连接反应在缓冲溶液中形成水凝胶，其中用于制备水凝胶的缓冲溶液的pH具有1.5至7.6的pH范围，并且缓冲溶液的浓度来自 约10mM至约100mM