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公开(公告)号:WO2009092551A3
公开(公告)日:2009-10-01
申请号:PCT/EP2009000294
申请日:2009-01-19
Applicant: BOEHRINGER INGELHEIM INT , VECTURA DELIVERY DEVICES LTD , EASON STEPHEN WILLIAM , SARKAR MATTHEW NEIL , GIBBINS GRAHAM ROGER , THOEMMES RALF , FRENTZEL-BEYME JESSICA , BESSELER JENS , VON BRUNN TIMO
Inventor: EASON STEPHEN WILLIAM , SARKAR MATTHEW NEIL , GIBBINS GRAHAM ROGER , THOEMMES RALF , FRENTZEL-BEYME JESSICA , BESSELER JENS , VON BRUNN TIMO
IPC: A61M15/00
CPC classification number: A61M15/0045 , A61M15/0026 , A61M15/0036 , A61M15/0041 , A61M15/0051 , A61M2202/064
Abstract: An inhaler (1) for delivery of a powder-form inhalation formulation from a blister strip (2) with a plurality of blister pockets (3) is proposed. A flexible guiding element (20) receives the used blisters strip.
Abstract translation: 提出了一种用于从具有多个泡罩袋(3)的泡罩带(2)输送粉末形式的吸入制剂的吸入器(1)。 柔性引导元件(20)容纳所使用的泡罩带。
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公开(公告)号:WO2009007351A2
公开(公告)日:2009-01-15
申请号:PCT/EP2008058808
申请日:2008-07-07
Applicant: VECTURA DELIVERY DEVICES LTD , EASON STEPHEN WILLIAM , SARKAR MATTHEW
Inventor: EASON STEPHEN WILLIAM , SARKAR MATTHEW
IPC: A61M15/00
CPC classification number: A61M15/0045 , A61M15/0051 , A61M15/0055 , A61M15/0056 , A61M15/0078
Abstract: An inhaler is disclosed. It comprises a housing to receive an elongate strip of blisters each containing a dose of medicament and being sequentially movable into alignment with means for breaching a blister to enable a user to inhale said dose contained therein. The device comprises an unused and a used blister compartment separated by a wall which may be moulded integrally with the housing of the device.
Abstract translation: 公开了一种吸入器。 它包括一个容纳细长带状泡罩的外壳,每个泡罩含有一定剂量的药剂,并顺序地与用于破坏泡罩的装置对齐,以使使用者能够吸入包含在其中的所述剂量。 该装置包括未被使用的和被使用的泡罩隔室,该隔室被可以与该装置的壳体一体模制的壁分开。
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公开(公告)号:WO2009007067A2
公开(公告)日:2009-01-15
申请号:PCT/EP2008005492
申请日:2008-07-04
Applicant: BOEHRINGER INGELHEIM INT , VECTURA DELIVERY DEVICES LTD , VON BRUNN TIMO
Inventor: VON BRUNN TIMO
IPC: A61M15/00
CPC classification number: A61M15/0045 , A61M15/0026 , A61M15/0035 , A61M15/0051 , A61M15/0055 , A61M15/0091 , A61M2202/064
Abstract: An inhaler for delivery of a powder-form inhalation formulation from a blister strip with a plurality of blister pockets is proposed. The used part of the blister strip is wound up and/or kept taut and/or free of loops by means of a spring.
Abstract translation: 提出了一种用于从具有多个泡罩袋的泡罩条输送粉末形式的吸入制剂的吸入器。 通过弹簧将泡罩带的使用部分卷起和/或保持拉紧和/或没有环。
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公开(公告)号:WO2010086285A3
公开(公告)日:2011-12-29
申请号:PCT/EP2010050790
申请日:2010-01-25
Applicant: VECTURA DELIVERY DEVICES LTD , WRIGHT MATTHEW PAUL , SHELDON MICHAEL , SARKAR MATTHEW , MILIVOJEVIC IVAN , CLARKE ROGER WILLIAM , WILLIAMSON EMMA LESLEY
Inventor: WRIGHT MATTHEW PAUL , SHELDON MICHAEL , SARKAR MATTHEW , MILIVOJEVIC IVAN , CLARKE ROGER WILLIAM , WILLIAMSON EMMA LESLEY
IPC: A61M15/00
CPC classification number: A61M15/0028 , A61M15/0026 , A61M15/0038 , A61M15/0091 , A61M15/0093 , A61M2202/064 , A61M2206/16
Abstract: An inhalation device (1) comprising a base having a slot for insertion of a single blister containing a dose of medicament to be inhaled into the base is disclosed. The inhaler has a mouthpiece (2) pivotally mounted to the base which carries a blister piercing element (14, 15) operable to pierce a blister received in said slot when th mouthpiece is pivoted relative to the base. When a user inhales on the mouthpiece, the dose is entrained in an airflow and flows out of the blister through the mouthpiece and into the user's airway.
Abstract translation: 公开了一种吸入装置(1),其包括具有用于插入含有一定剂量的待吸入基底的药物的单个泡罩的狭槽的底座。 吸入器具有枢转地安装到基座的接口管(2),所述接口管(2)枢转地安装到所述基座,所述接口管(2)枢转地安装在所述接口件相对于所述基座枢转 当用户吸入口腔时,剂量被夹带在气流中,并通过吸嘴流出泡罩并进入使用者的气道。
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公开(公告)号:WO2010070329A2
公开(公告)日:2010-06-24
申请号:PCT/GB2009051710
申请日:2009-12-14
Applicant: BOEHRINGER INGELHEIM INT , VECTURA DELIVERY DEVICES LTD , BESSELER JENS , DUNNE STEPHEN , JUNG ANDREE , KAEMPER MARKUS , KRAKOWKA MANUEL , WACHTEL HERBERT , EASON STEPHEN
Inventor: BESSELER JENS , DUNNE STEPHEN , JUNG ANDREE , KAEMPER MARKUS , KRAKOWKA MANUEL , WACHTEL HERBERT , EASON STEPHEN
IPC: A61M15/00
CPC classification number: A61M15/0045 , A61M15/0035 , A61M15/0036 , A61M15/0041 , A61M15/0051 , A61M2202/064
Abstract: An inhaler is proposed for delivering a preferably powdered formulation from a blister strip having a plurality of blister pockets. Each blister pockets is pierced such that an inlet opening and an outlet opening is formed in a lid of the respective blister pocket. A sealing is provided between the two openings and/or only around the outlet opening in order to avoid a bypass gas/air stream. Alternatively, a blister strip is proposed which comprises sealings on lids of its blister pockets.
Abstract translation: 提出一种吸入器用于从具有多个泡罩袋的泡罩带输送优选粉末制剂。 每个泡罩袋被刺穿,使得入口开口和出口开口形成在相应泡罩袋的盖子中。 在两个开口之间和/或仅在出口周围设置密封,以避免旁路气体/空气流。 或者,提出了一种泡罩带,其包括在其泡罩袋的盖上的密封。
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公开(公告)号:WO2009092434A3
公开(公告)日:2009-11-05
申请号:PCT/EP2008011126
申请日:2008-12-29
Applicant: BOEHRINGER INGELHEIM INT , VECTURA DELIVERY DEVICES LTD , WACHTEL HERBERT , HARMER QUENTIN JOHN , SARKAR MATTHEW NEIL , MILIVOJEVIC IVAN
Inventor: WACHTEL HERBERT , HARMER QUENTIN JOHN , SARKAR MATTHEW NEIL , MILIVOJEVIC IVAN
IPC: A61M15/00
CPC classification number: A61M15/0005 , A61M11/002 , A61M15/0008 , A61M15/0026 , A61M15/0045 , A61M15/0051 , A61M15/0055 , A61M15/0058 , A61M15/0085 , A61M15/009 , A61M2202/064 , A61M2206/16
Abstract: A passive inhaler (1) for delivery of a powder-form inhalation formulation from a blister strip (2) with a plurality of blister pockets (3) is proposed. The inhaler comprises an impaction element (31) onto which the air stream can impact together with entrained inhalation formulation for better deagglomeration. Alternatively, the inhaler comprises an oscillating and/or vibrating device (35) for better de- agglomeration of the inhalation formulation. Alternatively or additionally, the inhaler comprises one or two mixing means for generating swirls, preferably with opposite rotation directions.
Abstract translation: 提出了一种用于从具有多个泡罩袋(3)的泡罩条(2)输送粉末形式的吸入制剂的被动吸入器(1)。 吸入器包括冲击元件(31),空气流可以与夹带的吸入制剂一起冲击到冲击元件(31)上以便更好的解聚。 或者,吸入器包括用于更好地吸收制剂团聚的振荡和/或振动装置(35)。 或者或另外,吸入器包括用于产生涡流的一个或两个混合装置,优选地具有相反的旋转方向。
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公开(公告)号:WO2009007352A2
公开(公告)日:2009-01-15
申请号:PCT/EP2008058810
申请日:2008-07-07
Applicant: VECTURA DELIVERY DEVICES LTD , EASON STEPHEN WILLILAM , SARKAR MATTHEW , GIBBINS GRAHAM , CAMPLING NICHOLAS JOHN , BIDDLE HOWARD WILLIAM , THORNHILL TRISTIAN ROGER , BRADLEY DUNCAN JAMES
Inventor: EASON STEPHEN WILLILAM , SARKAR MATTHEW , GIBBINS GRAHAM , CAMPLING NICHOLAS JOHN , BIDDLE HOWARD WILLIAM , THORNHILL TRISTIAN ROGER , BRADLEY DUNCAN JAMES
IPC: A61M15/00
CPC classification number: A61M15/0045 , A61M15/0035 , A61M15/0041 , A61M15/0051 , A61M15/0055 , A61M15/0056 , A61M15/0058 , A61M15/0081 , A61M2202/064
Abstract: An inhaler is disclosed. It comprises a housing to receive an elongate strip of blisters each containing a dose of medicament and being sequentially movable into alignment with means for breaching a blister to enable a user to inhale said dose contained therein. The device comprises a spiral wound element within the housing that receives and coils said strip of blisters that have been breached.
Abstract translation: 公开了一种吸入器。 它包括一个容纳一个细长条状的泡罩的外壳,每一个都含有一定剂量的药物,并且可以顺序地移动到与破坏泡罩的装置对准,以使使用者能够吸入其中所含的所述剂量。 该装置包括壳体内的螺旋缠绕元件,其接收并卷绕已被破坏的所述水泡条。
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公开(公告)号:WO2012069854A3
公开(公告)日:2012-07-19
申请号:PCT/GB2011052338
申请日:2011-11-25
Applicant: VECTURA DELIVERY DEVICES LTD , MELINIOTIS ANDREAS , EASON STEPHEN , CLARKE ROGER , MCGUINNESS LIAM
Inventor: MELINIOTIS ANDREAS , EASON STEPHEN , CLARKE ROGER , MCGUINNESS LIAM
IPC: A61M15/00
CPC classification number: A61M15/0058 , A61M15/0021 , A61M15/0026 , A61M15/0033 , A61M15/0045 , A61M15/0051 , A61M15/0056 , A61M15/0081 , A61M15/08
Abstract: An inhaler comprising a housing defining a chamber to receive a strip having a plurality of blisters each containing a dose of medicament for inhalation by a user is disclosed. It comprises an actuating lever (14) and a blister strip drive member rotatably mounted in the chamber to sequentially move each blister into a blister opening position. The blister strip drive member and the actuating lever comprise a drive gear (16) and a drive gear element (28), respectively, that cooperate to effect rotation of the blister strip drive member in response to rotation of the actuating lever. The drive gear and drive gear element are disposed on the outside of the housing remote from the chamber.
Abstract translation: 一种吸入器,其包括限定腔室的壳体,以容纳具有多个泡罩的条带,每个泡罩包含一定剂量的用户吸入的药物。 其包括致动杆(14)和可旋转地安装在腔室中的泡罩条驱动构件,以顺序地将每个泡罩移动到泡罩打开位置。 泡罩带驱动构件和致动杆分别包括驱动齿轮(16)和驱动齿轮元件(28),所述驱动齿轮(16)和驱动齿轮元件(28)协作以响应于致动杆的旋转而实现泡罩带驱动构件的旋转。 驱动齿轮和驱动齿轮元件设置在远离腔室的外壳的外侧。
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公开(公告)号:WO2010040779A3
公开(公告)日:2010-07-01
申请号:PCT/EP2009063038
申请日:2009-10-07
Applicant: VECTURA DELIVERY DEVICES LTD , SARKAR MATTHEW , MAY ROBERT , TWEEDIE ALAN , HARDMAN PAUL
Inventor: SARKAR MATTHEW , MAY ROBERT , TWEEDIE ALAN , HARDMAN PAUL
IPC: A61M15/00
CPC classification number: A61M15/0045 , A61M11/003 , A61M15/0021 , A61M15/0036 , A61M15/0051 , A61M2202/064 , A61M2206/16
Abstract: An inhaler (1) for producing an inhalable aerosol of powdered medicament is disclosed. The inhaler (1) comprises an aerosolising device having a cyclone chamber (45) of substantially circular cross-section, inlet (24) and outlet (25) ports at opposite ends of the chamber (45) for the flow of drug laden air through the chamber (45) between said ports (24, 25) and, a bypass air inlet (46) for the flow of clean air into the chamber (45). The bypass air inlets (46) are configured so that air entering the chamber (45) through said inlet (46) forms a cyclone in the chamber (45) that interacts with the drug laden air flowing between the inlet (24) and outlet (25) ports. The inhaler (1) may have a tapered drug laden air flow conduit (70) to accelerate the flow prior to entry into the chamber (45) and/or an impaction element (81, 84, 92, 105) to deagglomerate drug particles.
Abstract translation: 公开了一种用于产生粉末状药物的吸入性气溶胶的吸入器(1)。 吸入器(1)包括雾化装置,其具有基本上圆形横截面的旋风室(45),在室(45)的相对端处的入口(24)和出口(25)端口,用于使载满载货的空气流过 在所述端口(24,25)之间的所述腔室(45)和用于将清洁空气流入所述腔室(45)的旁路空气入口(46)。 旁路空气入口(46)构造成使得通过所述入口(46)进入腔室(45)的空气在腔室(45)中形成旋流器,其与在入口(24)和出口(24)之间流动的载药空气相互作用, 25)端口。 吸入器(1)可以具有锥形药物负载空气流动管道(70),以在进入腔室(45)和/或冲击元件(81,84,92,105)之间加速流动以使药物颗粒解聚。
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公开(公告)号:WO2009092651A2
公开(公告)日:2009-07-30
申请号:PCT/EP2009050343
申请日:2009-01-14
Applicant: VECTURA DELIVERY DEVICES LTD , GIBBINS GRAHAM , EVANS PETER , SARKAR MATTHEW
Inventor: GIBBINS GRAHAM , EVANS PETER , SARKAR MATTHEW
IPC: A61M15/00
CPC classification number: A61M15/0045 , A61M15/0041 , A61M15/0051 , A61M2202/064
Abstract: A method of coiling a strip of blisters for insertion into an inhalation device is disclosed. The method includes the steps of taking a preformed strip of blisters in which each blister contains a dose of medicament for inhalation by a user, manipulating the strip to impart a continuous curvature or a series of discrete creases to the strip; that allow the strip to form into a coiled shape. A strip which has been coiled according to the method is also disclosed, as is an inhalation device incorporating means for coiling a strip of blisters according to the invention.
Abstract translation: 公开了一种盘绕泡罩条以插入吸入装置的方法。 该方法包括以下步骤:取出预成型的泡罩条,其中每个泡罩包含一定剂量的药物以供使用者吸入,操纵条带以赋予条带连续的曲率或一系列离散的折痕; 这允许条形成卷曲形状。 还公开了根据该方法盘绕的条带,以及包含用于卷绕根据本发明的泡罩条带的装置的吸入装置。
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