公开(公告)号：WO2010084415A1

公开(公告)日：2010-07-29

申请号：PCT/IB2010/000115

申请日：2010-01-22

Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH ,  WACHTEL, Herbert ,  JUNG, Andree ,  BESSELER, Jens ,  KRAKOWKA, Manuel

Inventor： WACHTEL, Herbert ,  JUNG, Andree ,  BESSELER, Jens ,  KRAKOWKA, Manuel

IPC: A61M15/00

CPC classification number: A61M15/0045 ,  A61M15/0021 ,  A61M15/0035 ,  A61M15/0038 ,  A61M15/0041 ,  A61M15/0051 ,  A61M15/0055 ,  A61M2202/064

Abstract: A passive inhaler for delivery of a powder-form inhalation formulation from a blister strip with a plurality of blister pockets is proposed. The inhaler comprises a metallic piercing member with two piercing elements extending at least essentially in V-shape away from each other and being at least essentially flat. A contact member is arranged between the piercing elements to contact a lid of a blister pocket in an area between separate openings formed by the piercing elements in the lid,

Abstract translation: 提出了一种用于从具有多个泡罩袋的泡罩条输送粉末形式的吸入制剂的被动吸入器。 吸入器包括具有两个刺穿元件的金属刺穿构件，两个刺穿元件至少基本上彼此延伸成V形，至少基本上是平的。 接触构件设置在穿刺元件之间，以在由盖中的穿孔元件形成的分开的开口之间的区域中接触泡罩袋的盖，

公开(公告)号：WO2008145348A3

公开(公告)日：2009-01-29

申请号：PCT/EP2008004228

申请日：2008-05-28

Applicant: BOEHRINGER INGELHEIM INT ,  THOEMMES RALF ,  VON BRUNN TIMO ,  BESSELER JENS ,  FISCHER BASTIAN

Inventor： THOEMMES RALF ,  VON BRUNN TIMO ,  BESSELER JENS ,  FISCHER BASTIAN

IPC: A61M11/02 ,  A61M15/00

CPC classification number: A61M15/0045 ,  A61M11/001 ,  A61M11/02 ,  A61M15/0026 ,  A61M15/0036 ,  A61M15/0041 ,  A61M15/0048 ,  A61M15/005 ,  A61M15/0061 ,  A61M15/0075 ,  A61M15/0081 ,  A61M2016/0021 ,  A61M2016/0039 ,  A61M2202/064 ,  A61M2205/071

Abstract: A dispensing device (1) and a storage device (4) are proposed for dispensing a formulation (2) as a spray (3). The storage device comprises multiple separate and pre-metered doses of the formulation in receptacles or cavities (7). In order to allow a very com pact arrangement, the receptacles or cavities are arranged in a first group and a second group axially offset and preferably forming a double-ring arrangement.

Abstract translation: 提出了一种分配装置（1）和存储装置（4），用于分配作为喷雾剂（3）的制剂（2）。 存储装置包括在容器或空腔（7）中的多个单独的和预定量的制剂剂量。 为了允许非常紧凑的布置，插座或空腔被布置成第一组和第二组轴向偏置并且优选地形成双环布置。

公开(公告)号：WO2008138632A1

公开(公告)日：2008-11-20

申请号：PCT/EP2008/003926

申请日：2008-05-15

Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH ,  ROHRSCHNEIDER, Marc ,  BESSELER, Jens ,  VON BRUNN, Timo ,  REINHOLD, Thomas, Sowden

Inventor： ROHRSCHNEIDER, Marc ,  BESSELER, Jens ,  VON BRUNN, Timo ,  REINHOLD, Thomas, Sowden

IPC: A61M15/00

CPC classification number: A61M15/0045 ,  A61M11/001 ,  A61M15/0008 ,  A61M15/0031 ,  A61M15/0036 ,  A61M15/0041 ,  A61M15/0048 ,  A61M15/0061 ,  A61M15/0075 ,  A61M2016/0039 ,  A61M2202/064 ,  A61M2205/07 ,  A61M2205/8225 ,  A61M2205/8293

Abstract: A dispensing device (1) having a storage device (4) and an air pump (18) for dispensing a medical formulation is proposed. The storage device comprises multiple inserts (6), each insert containing a single dose of the formulation. Each insert is located in a separate and sealed cavity. The cavities can be individually opened for dispensing the respective dose from the respective insert.

Abstract translation: 提出了一种具有储存装置（4）和用于分配医用制剂的空气泵（18）的分配装置（1）。 存储装置包括多个插入物（6），每个插入物含有单剂量的制剂。 每个插入件都位于一个独立且密封的腔中。 可以单独打开空腔以从相应的插入件分配相应的剂量。

公开(公告)号：WO2007134792A1

公开(公告)日：2007-11-29

申请号：PCT/EP2007/004416

申请日：2007-05-16

Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH ,  THOEMMES, Ralf ,  BESSELER, Jens ,  WESTMEIER, Birgit ,  FRENTZEL-BEYME, Jessica

Inventor： THOEMMES, Ralf ,  BESSELER, Jens ,  WESTMEIER, Birgit ,  FRENTZEL-BEYME, Jessica

IPC: A61M15/00

CPC classification number: A61M15/0045 ,  A61M15/0026 ,  A61M15/0035 ,  A61M15/004 ,  A61M15/0051

Abstract: An inhaler is proposed, for delivering a preferably powdered formulation from a blister strip (3) having a plurality of blister pouches (4). In order to achieve a compact simple construction for the inhaler and an easy action for the blister strip, the carrier extends over a circumferential angle of the inhaler of less than 360-. In particular, the carrier is guided between two deflectors (8) with an at least substantially constant curvature and preferably exclusively along an outer wall of the inhaler. A conveying device (5) of the inhaler comprises four drive wheels (12) of the same diameter which are arranged on a common radius and are driven by common drive means in the same direction of rotation.

Abstract translation: 提出了一种用于从具有多个泡罩袋（4）的泡罩条（3）输送优选粉末制剂的吸入器。 为了实现用于吸入器的紧凑的简单结构和用于泡罩条的容易的动作，载体在小于360度的吸入器的圆周角度上延伸。 特别地，载体在两个偏转器（8）之间以至少基本上恒定的曲率被引导，并且优选地仅沿着吸入器的外壁被引导。 吸入器的输送装置（5）包括相同直径的四个驱动轮（12），其布置在共同的半径上并且由相同的旋转方向的公共驱动装置驱动。

公开(公告)号：WO2010094305A1

公开(公告)日：2010-08-26

申请号：PCT/EP2009/005949

申请日：2009-08-17

Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH ,  DUNNE, Stephen T. ,  HOLAKOVSKY, Holger ,  BACH, Alexander ,  BESSELER, Jens ,  KRAKOWKA, Manuel ,  WUTTKE, Gilbert

Inventor： DUNNE, Stephen T. ,  HOLAKOVSKY, Holger ,  BACH, Alexander ,  BESSELER, Jens ,  KRAKOWKA, Manuel ,  WUTTKE, Gilbert

IPC: B05B11/04

CPC classification number: A61M15/009 ,  A61M15/0065 ,  A61M15/0081 ,  A61M2202/0468 ,  B05B11/0037 ,  B05B11/0043 ,  B05B11/0054 ,  B05B11/3091

Abstract: A device, cartridge and method for dispensing a liquid (103), preferably a drug, are proposed. The liquid is pressurized in a cartridge to a first lower pressure and, then, pressurized in doses by a pump (117) to a second higher pressure. A valve (106) arranged between the cartridge (100) and the pump (117) is normally closed and/or opened only temporarily. Thus, evaporation and dripping of liquid can be avoided or minimized.

Abstract translation: 提出了用于分配液体（103），优选药物的装置，盒和方法。 将液体在筒中加压至第一较低压力，然后通过泵（117）以剂量加压至第二较高压力。 布置在盒（100）和泵（117）之间的阀（106）通常仅被暂时关闭和/或打开。 因此，可以避免或最小化液体的蒸发和滴落。

公开(公告)号：WO2010070329A3

公开(公告)日：2010-06-24

申请号：PCT/GB2009/051710

申请日：2009-12-14

Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GmbH ,  VECTURA DELIVERY DEVICES LIMITED ,  BESSELER, Jens ,  DUNNE, Stephen ,  JUNG, Andree ,  KAEMPER, Markus ,  KRAKOWKA, Manuel ,  WACHTEL, Herbert ,  EASON, Stephen

Inventor： BESSELER, Jens ,  DUNNE, Stephen ,  JUNG, Andree ,  KAEMPER, Markus ,  KRAKOWKA, Manuel ,  WACHTEL, Herbert ,  EASON, Stephen

IPC: A61M15/00

Abstract: An inhaler is proposed for delivering a preferably powdered formulation from a blister strip having a plurality of blister pockets. Each blister pockets is pierced such that an inlet opening and an outlet opening is formed in a lid of the respective blister pocket. A sealing is provided between the two openings and/or only around the outlet opening in order to avoid a bypass gas/air stream. Alternatively, a blister strip is proposed which comprises sealings on lids of its blister pockets.

公开(公告)号：WO2009092592A1

公开(公告)日：2009-07-30

申请号：PCT/EP2009/000423

申请日：2009-01-23

Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH ,  THOEMMES, Ralf ,  BESSELER, Jens ,  FRENTZEL-BEYME, Jessica

Inventor： THOEMMES, Ralf ,  BESSELER, Jens ,  FRENTZEL-BEYME, Jessica

IPC: A61M15/00

CPC classification number: A61M15/0045 ,  A61M15/0026 ,  A61M15/0036 ,  A61M15/0051 ,  A61M15/0065 ,  A61M15/0078 ,  A61M15/0081 ,  A61M15/0096 ,  A61M2202/064

Abstract: An inhaler (1) for delivery of a powder-form inhalation formulation from a blister strip (2) with a plurality of blister pockets (3) is proposed. A tape is used for numbering.

Abstract translation: 提出了一种用于从具有多个泡罩袋（3）的泡罩带（2）输送粉末形式的吸入制剂的吸入器（1）。 磁带用于编号。

公开(公告)号：WO2009092551A2

公开(公告)日：2009-07-30

申请号：PCT/EP2009/000294

申请日：2009-01-19

Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH ,  VECTURA DELIVERY DEVICES LIMITED ,  EASON, Stephen William ,  SARKAR, Matthew Neil ,  GIBBINS, Graham Roger ,  THOEMMES, Ralf ,  FRENTZEL-BEYME, Jessica ,  BESSELER, Jens ,  VON BRUNN, Timo

Inventor： EASON, Stephen William ,  SARKAR, Matthew Neil ,  GIBBINS, Graham Roger ,  THOEMMES, Ralf ,  FRENTZEL-BEYME, Jessica ,  BESSELER, Jens ,  VON BRUNN, Timo

IPC: A61M15/00

CPC classification number: A61M15/0045 ,  A61M15/0026 ,  A61M15/0036 ,  A61M15/0041 ,  A61M15/0051 ,  A61M2202/064

Abstract: An inhaler for delivery of a powder-form inhalation formulation from a blister strip with a plurality of blister pockets is proposed. A flexible guiding element receives the used blisters strip.

Abstract translation: 提出了一种用于从具有多个泡罩袋的泡罩条输送粉末形式的吸入制剂的吸入器。 柔性引导元件接收使用过的气泡条。

公开(公告)号：WO2010070329A2

公开(公告)日：2010-06-24

申请号：PCT/GB2009051710

申请日：2009-12-14

Applicant: BOEHRINGER INGELHEIM INT ,  VECTURA DELIVERY DEVICES LTD ,  BESSELER JENS ,  DUNNE STEPHEN ,  JUNG ANDREE ,  KAEMPER MARKUS ,  KRAKOWKA MANUEL ,  WACHTEL HERBERT ,  EASON STEPHEN

Inventor： BESSELER JENS ,  DUNNE STEPHEN ,  JUNG ANDREE ,  KAEMPER MARKUS ,  KRAKOWKA MANUEL ,  WACHTEL HERBERT ,  EASON STEPHEN

IPC: A61M15/00

CPC classification number: A61M15/0045 ,  A61M15/0035 ,  A61M15/0036 ,  A61M15/0041 ,  A61M15/0051 ,  A61M2202/064

Abstract: An inhaler is proposed for delivering a preferably powdered formulation from a blister strip having a plurality of blister pockets. Each blister pockets is pierced such that an inlet opening and an outlet opening is formed in a lid of the respective blister pocket. A sealing is provided between the two openings and/or only around the outlet opening in order to avoid a bypass gas/air stream. Alternatively, a blister strip is proposed which comprises sealings on lids of its blister pockets.

Abstract translation: 提出一种吸入器用于从具有多个泡罩袋的泡罩带输送优选粉末制剂。 每个泡罩袋被刺穿，使得入口开口和出口开口形成在相应泡罩袋的盖子中。 在两个开口之间和/或仅在出口周围设置密封，以避免旁路气体/空气流。 或者，提出了一种泡罩带，其包括在其泡罩袋的盖上的密封。

公开(公告)号：WO2009132791A8

公开(公告)日：2010-02-25

申请号：PCT/EP2009002912

申请日：2009-04-22

Applicant: BOEHRINGER INGELHEIM INT ,  KAEMPER MARKUS ,  BESSELER JENS

Inventor： KAEMPER MARKUS ,  BESSELER JENS

IPC: A61M15/00

CPC classification number: A61M15/0045 ,  A61M11/02 ,  A61M15/0026 ,  A61M15/0035 ,  A61M15/0051 ,  A61M15/0081 ,  A61M2202/064

Abstract: An inhaler (1) is proposed for delivering a preferably powdered formulation from a blister strip (3) having a plurality of blister pockets (4). The inhaler comprises a life span blocking device (31) which blocks opening of a cover (15) of the inhaler in a blocking state by means of locking element (39) interlocking the cover with a housing (19) of the inhaler.

Abstract translation: 提出了一种吸入器（1），用于从具有多个泡罩袋（4）的泡罩条（3）输送优选粉末制剂。 吸入器包括一个使用寿命的阻塞装置（31），其借助于将盖与吸入器的壳体（19）互锁的锁定元件（39）阻挡吸入器的盖（15）的打开状态。