公开(公告)号：WO2012017227A1

公开(公告)日：2012-02-09

申请号：PCT/GB2011/051413

申请日：2011-07-25

Applicant: THE UNIVERSITY OF WARWICK ,  WARD, Peter ,  MAWBY, Philip ,  WESTMORELAND, Martin

Inventor： WARD, Peter ,  MAWBY, Philip ,  WESTMORELAND, Martin

IPC: H01L29/739 ,  H01L21/331 ,  H01L29/06

CPC classification number: H01L29/7802 ,  H01L29/0634 ,  H01L29/47 ,  H01L29/66053 ,  H01L29/66325 ,  H01L29/7393 ,  H01L29/7395 ,  H01L29/7803 ,  H01L29/7806

Abstract: A semiconductor device operable as a vertical metal oxide semiconductor field effect transistor and a vertical or lateral insulated gate bipolar transistor is disclosed. The device has a Schottky-biased p-n junction.

Abstract translation: 公开了可操作为垂直金属氧化物半导体场效应晶体管和垂直或横向绝缘栅双极晶体管的半导体器件。 该器件具有肖特基偏置p-n结。

公开(公告)号：WO2011064603A1

公开(公告)日：2011-06-03

申请号：PCT/GB2010/051988

申请日：2010-11-30

Applicant: PIPELINE INNOVATIONS LIMITED ,  HILL, Rennie ,  THOMPSON, David ,  WARD, Peter

Inventor： HILL, Rennie ,  THOMPSON, David ,  WARD, Peter

IPC: F16L55/28 ,  F16L55/40

CPC classification number: F16L55/28 ,  F16L55/40

Abstract: An instrumented pig comprises a foam body having an outer surface and an inner cavity in which, in use, is located a sealed unit housing at least a part of a parameter measurement apparatus configured to measure at least one parameter from which the extent of deflection of the outer surface of the foam body may be derived, the sealed unit including at least one sensor configured to generate an output signal representative of the at least one measured parameter.

Abstract translation: 仪表式猪包括具有外表面和内腔的泡沫体，在使用中，所述发泡体位于密封单元中，所述密封单元容纳参数测量装置的至少一部分，所述参数测量装置被配置成测量至少一个参数， 可以导出泡沫体的外表面，密封单元包括至少一个被配置为产生表示至少一个测量参数的输出信号的传感器。

公开(公告)号：WO2009016407A2

公开(公告)日：2009-02-05

申请号：PCT/GB2008050641

申请日：2008-07-30

Applicant: SENSL TECHNOLOGIES LTD ,  JACKSON JOHN CARLTON ,  HUGHES PADRAIG JOSEPH ,  WARD PETER JOHN

Inventor： JACKSON JOHN CARLTON ,  HUGHES PADRAIG JOSEPH ,  WARD PETER JOHN

IPC: H01L27/146 ,  H01L23/498

CPC classification number: H01L27/14634 ,  H01L27/14609 ,  H01L27/14636 ,  H01L27/1469 ,  H01L31/107 ,  H01L2224/45144 ,  H01L2224/48091 ,  H01L2924/01077 ,  H01L2924/01079 ,  H01L2924/09701 ,  H01L2924/10253 ,  H01L2924/00014 ,  H01L2924/00

Abstract: A method is provided of forming a light sensing array for use in a light sensor. The method comprises tiling a plurality of individual light sensing elements on a carrier, each element having a notch formed in an edge thereof, the notch being adapted to provide space, when the elements are tiled together, for an electrical connection to be made between the carrier and a surface of the element arranged to faced away from the carrier. Each element may comprise Silicon Photomultiplier (SPM) circuitry.

Abstract translation: 提供一种形成用于光传感器的光感测阵列的方法。 该方法包括在载体上平铺多个单独的光感测元件，每个元件具有形成在其边缘中的凹口，所述凹口适于在元件平铺在一起时提供空间，用于在 载体和元件的表面布置成面向远离载体。 每个元件可以包括硅光电倍增管（SPM）电路。

公开(公告)号：WO2009006246A1

公开(公告)日：2009-01-08

申请号：PCT/US2008068465

申请日：2008-06-27

Applicant: ALEA THERAPEUTICS CORP ,  PATERSON BLAKE ,  WARD PETER ,  FASANO ALESSIO

Inventor： PATERSON BLAKE ,  WARD PETER ,  FASANO ALESSIO

IPC: A61K38/04 ,  C07K5/00 ,  C07K7/00

CPC classification number: C07K7/06 ,  A61K9/007 ,  A61K38/00 ,  A61K38/08 ,  A61K45/06

Abstract: The present application provides compositions and methods for treating acute lung injury and acute respiratory distress syndrome. The methods include administering one or more tight junction antagonists to the lung of a subject in need thereof.

Abstract translation: 本申请提供治疗急性肺损伤和急性呼吸窘迫综合征的组合物和方法。 所述方法包括向有需要的受试者的肺部施用一个或多个紧密连接的拮抗剂。

公开(公告)号：WO2007062455A1

公开(公告)日：2007-06-07

申请号：PCT/AU2006/001779

申请日：2006-11-24

Applicant: SPA ELECTRICS PTY LTD ,  WARD, Peter

Inventor： WARD, Peter

IPC: F21V29/00 ,  F21L4/00 ,  H01L33/00 ,  B60Q1/00 ,  F21S2/00 ,  H05B37/02 ,  B60Q1/08 ,  F21S8/04

CPC classification number: F21V29/89 ,  F21S8/00 ,  F21V23/0442 ,  F21V25/10 ,  F21W2131/401 ,  F21Y2115/10 ,  Y10S362/80

Abstract: An underwater luminaire including a lighting element in thermal communication with a heat dissipating means, the heat dissipating means (35) being configured to dissipate heat through water surrounding the luminaire, the heat dissipating means being associated with an electrical power limiting means (58) that includes a temperature detector (59) wherein the electrical power limiting means limits the electrical power supplied to the lighting element in the event the temperature detector indicates a temperature that exceeds a predetermined limit.

Abstract translation: 一种包括与散热装置热连通的照明元件的水下照明装置，所述散热装置（35）构造成通过围绕所述照明装置的水散热，所述散热装置与电力限制装置（58）相关联，所述电力限制装置 包括温度检测器（59），其中在温度检测器指示超过预定极限的温度的情况下，电力限制装置限制供应给照明元件的电力。

公开(公告)号：WO2004024728A3

公开(公告)日：2004-10-21

申请号：PCT/EP0311814

申请日：2003-09-12

Applicant: GLAXO GROUP LTD ,  ALLEN DAVID GEORGE ,  COE DIANE MARY ,  COOK CAROLINE MARY ,  DOWLE MICHAEL DENNIS ,  EDLIN CHRISTOPHER DAVID ,  HAMBLIN JULIE NICOLE ,  JOHNSON MARTIN REDPATH ,  JONES PAUL SPENCER ,  KNOWLES RICHARD GRAHAM ,  LINDVALL MIKA KRISTIAN ,  MITCHELL CHARLOTTE JANE ,  REDGRAVE ALISON JUDITH ,  TRIVEDI NAIMISHA ,  WARD PETER

Inventor： ALLEN DAVID GEORGE ,  COE DIANE MARY ,  COOK CAROLINE MARY ,  DOWLE MICHAEL DENNIS ,  EDLIN CHRISTOPHER DAVID ,  HAMBLIN JULIE NICOLE ,  JOHNSON MARTIN REDPATH ,  JONES PAUL SPENCER ,  KNOWLES RICHARD GRAHAM ,  LINDVALL MIKA KRISTIAN ,  MITCHELL CHARLOTTE JANE ,  REDGRAVE ALISON JUDITH ,  TRIVEDI NAIMISHA ,  WARD PETER

IPC: A61K31/437 ,  A61P11/00 ,  A61P29/00 ,  C07D221/00 ,  C07D231/00 ,  C07D471/04

CPC classification number: C07D471/04

Abstract: The invention relates to a compound of formula (I) or a salt thereof: wherein:R1 is C1-4alkyl, C1-3fluoroalkyl, -CH2CH2OH or -CH2CH2CO2C1-2alkyl;R2 is a hydrogen atom (H), methyl or C1fluoroalkyl;R3 is optionally substituted C3-8cycloalkyl or optionally substituted mono-unsaturated-C5-7cycloalkenyl or an optionally substituted heterocyclic group of sub-formula (aa), (bb) or (cc); in which n1 and n2 independently are 1 or 2; and in which Y is O, S, SO2, or NR10; or R3 is a bicyclic group (dd) or (ee): ; and wherein X is NR4R5 or OR5a. The compounds are phosphodiesterase (PDE) inhibitors, in particular PDE4 inhibitors. Also provided is the use of a compound of formula (I), or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the treatment and/or prophylaxis of an inflammatory and/or allergic disease in a mammal such as a human, for example chronic obstructive pulmonary disease (COPD), asthma, or allergic rhinitis.

Abstract translation: 本发明涉及式（I）化合物或其盐：其中：R 1为C 1-4烷基，C 1-3氟烷基，-CH 2 CH 2 OH或-CH 2 CH 2 CO 2 C 1-2烷基; R 2为氢原子（H），甲基或C 1-3氟烷基; （aa），（bb）或（cc）的任选取代的C 3-8环烷基或任选取代的单不饱和-C 5-7环烯基或任选取代的杂环基; 其中n1和n2独立地为1或2; 并且其中Y是O，S，SO 2或NR 10; 或R3是双环基团（dd）或（ee）： 并且其中X是NR 4 R 5或OR 5 a。 这些化合物是磷酸二酯酶（PDE）抑制剂，特别是PDE4抑制剂。 还提供了式（I）化合物或其药学上可接受的盐在制备用于治疗和/或预防哺乳动物例如人的炎症和/或过敏性疾病的药物中的用途， 例如慢性阻塞性肺病（COPD），哮喘或过敏性鼻炎。

公开(公告)号：WO0230408A3

公开(公告)日：2003-11-06

申请号：PCT/US0131501

申请日：2001-10-10

Applicant: UNIV NORTH CAROLINA ,  THAKKER DHIREN R ,  WARD PETER D

Inventor： THAKKER DHIREN R ,  WARD PETER D

IPC: A61K45/00 ,  A61K31/353 ,  A61K31/37 ,  A61K31/56 ,  A61K31/58 ,  A61K31/661 ,  A61K31/685 ,  A61K45/06 ,  A61P1/14 ,  A61P25/00 ,  A61P43/00 ,  A61K31/00 ,  A61K47/22 ,  A61K47/24 ,  A61K47/28

CPC classification number: A61K45/06 ,  A61K31/353 ,  A61K31/37 ,  A61K31/58 ,  A61K31/685 ,  Y10S514/946

Abstract: Compositions and methods for enhancing paracellular permeability at an absorption site in a subject are disclosed. The method includes: (a) administering an effective amount of a phospholipase C inhibitor to a subject at a time in which enhanced paracellular permeability is desired; and (b) enhancing paracellular permaeability in the subject at the the absorption site through the administering of the effective amount of the phospholipase C inhibitor. The disclosed compositions and methods provide enhanced absorption of a hydrophilic drug in a subject.

Abstract translation: 公开了用于在受试者的吸收部位增强细胞旁渗透性的组合物和方法。 该方法包括：（a）在需要增加细胞旁渗透性的时间向受试者施用有效量的磷脂酶C抑制剂; 和（b）通过施用有效量的磷脂酶C抑制剂来增强受试者在吸收部位的细胞旁通能力。 所公开的组合物和方法提供了受试者中亲水药物的增强的吸收。

公开(公告)号：WO2002090221A1

公开(公告)日：2002-11-14

申请号：PCT/GB2002/002061

申请日：2002-05-03

Applicant: RMC (U.K.) LIMITED ,  HODDLE, Stephen ,  WARD, Peter

Inventor： HODDLE, Stephen ,  WARD, Peter

IPC: B65G53/66

CPC classification number: B60P1/60 ,  B65G53/22 ,  B65G53/66

Abstract: A transport container (10) defining a storage volume (11) for particulate matter having an outlet, means for pressurising (18) the storage volume (11) and means for aerating (16, 17) the particulate matter therein and a discharge valve (23) for regulating the flow of the aerated particulate matter through the outlet, wherein the container (10) further comprises a sensor (50) for detecting vibrations during discharge of said particulate matter and for thereby producing a signal indicating that the discharge valve (23) should be closed so as to prevent over-pressurisation of a receptacle (40) receiving said particulate matter.

Abstract translation: 限定用于具有出口的颗粒物质的储存容积（11）的运输容器（10），用于加压储存容积（11）的装置和用于将颗粒物质充气（16,17）的装置和排出阀（ 23），其用于调节通过出口的充气颗粒物质的流动，其中容器（10）还包括传感器（50），用于在所述颗粒物排出期间检测振动，从而产生指示排出阀（23 ）应当封闭，以便防止接收所述颗粒物质的容器（40）的过度加压。

公开(公告)号：WO1997016700A1

公开(公告)日：1997-05-09

申请号：PCT/GB1996002692

申请日：1996-11-01

Applicant: BRITISH GAS PLC ,  CORDES, Paul ,  McGONNELL, Philip ,  WARD, Peter ,  FRASER, Andrew, John

Inventor： BRITISH GAS PLC

IPC: G01B15/02

CPC classification number: G01B15/02

Abstract: A measuring device for determining the thickness of a non-homogenous medium such as the thickness or a road structure. The device includes a radar transmitter Tx and two spaced receivers Rx1, Rx2. Information on the timing of the transmitted signal as well as the signals received by the two receivers is used to calculate the material thickness whilst eliminating signal drift.

Abstract translation: 用于确定诸如厚度或道路结构之类的非均匀介质的厚度的测量装置。 该装置包括雷达发射机Tx和两个间隔开的接收机Rx1，Rx2。 关于发送信号的定时以及由两个接收机接收的信号的信息用于计算材料厚度同时消除信号漂移。

公开(公告)号：WO1994013893A1

公开(公告)日：1994-06-23

申请号：PCT/AU1993000618

申请日：1993-12-03

Applicant: WARD, Peter, John

IPC: E03D09/04

CPC classification number: F01D1/32 ,  E03D9/04 ,  F03B13/00 ,  F04D25/04 ,  F24F7/013 ,  F24F2005/006

Abstract: An exhaust fan is driven by a water turbine. The water turbine is connected between the water supply and point of use so that when the water is used, e.g., shower, bath, toilet, the fan is driven by the water turbine.

Abstract translation: 排风扇由水轮机驱动。 水轮机连接在供水和使用点之间，使得当使用水时，例如淋浴，浴室，马桶，风扇由水轮机驱动。