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1.发明申请3-OXA-10-AZA-PHENANTHRENES AS PDE4 OR PDE3/4 INHIBITORS 审中-公开3-OXA-10-AZA-PHENANTHRENES作为PDE4或PDE3 / 4抑制剂
公开(公告)号：WO2006027344A3
公开(公告)日：2006-07-27
申请号：PCT/EP2005054364
申请日：2005-09-05
申请人： ALTANA PHARMA AG , FLOCKERZI DIETER , KAUTZ ULRICH , HATZELMANN ARMIN , ZITT CHRISTOF , WOHLSEN ANDREA , MARX DEGENHARD , KLEY HANS-PETER , CHRISTOFFERS JENS , ROSIAK ANNA
发明人： FLOCKERZI DIETER , KAUTZ ULRICH , HATZELMANN ARMIN , ZITT CHRISTOF , WOHLSEN ANDREA , MARX DEGENHARD , KLEY HANS-PETER , CHRISTOFFERS JENS , ROSIAK ANNA
IPC分类号： C07D491/04 , A61K31/435 , C07D309/14 , C07D309/30
CPC分类号： C07D491/04
摘要： Compounds of a certain formula 1, in which R1, R2 and R3 have the meanings indicated in the description, are novel effective PDE4 inhibitors.
摘要翻译： R1，R2和R3具有说明书中所示含义的某种式1的化合物是新的有效的PDE4抑制剂。
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公开(公告)号：WO2006082185A1
公开(公告)日：2006-08-10
申请号：PCT/EP2006/050557
申请日：2006-01-31
申请人： ALTANA Pharma AG , KAUTZ, Ulrich , SCHMIDT, Beate , FLOCKERZI, Dieter , CHIESA, Maria Vittoria , HATZELMANN, Armin , ZITT, Christof , BARSIG, Johannes , WOHLSEN, Andrea , MARX, Degenhard , KLEY, Hans-peter
发明人： KAUTZ, Ulrich , SCHMIDT, Beate , FLOCKERZI, Dieter , CHIESA, Maria Vittoria , HATZELMANN, Armin , ZITT, Christof , BARSIG, Johannes , WOHLSEN, Andrea , MARX, Degenhard , KLEY, Hans-peter
IPC分类号： C07D401/04 , A61K31/473 , A61P11/06
CPC分类号： C07D401/04
摘要： Compounds of a certain formula I, in which R1, R2, R3, R31, R4, R5, R51 and Har have the meanings indicated in the description, are novel effective PDE4 inhibitors.
摘要翻译： 其中R1，R2，R3，R31，R4，R5，R51和Har具有说明书中所示含义的某种式I的化合物是新的有效的PDE4抑制剂。
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3.发明申请6 -HETEROARYL-1, 2, 3,4,4A, 1OB-HEXAHYDRO-PHENANTHRIDINES AS PDE-4 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISORDERS 审中-公开6 -HETEROARYL-1,2,4,4,4A，1-B-HEXAHYDRO-PHENANTHRIDINES作为治疗炎症性疾病的PDE-4抑制剂
公开(公告)号：WO2006092417A1
公开(公告)日：2006-09-08
申请号：PCT/EP2006/060370
申请日：2006-03-01
申请人： ALTANA PHARMA AG , KAUTZ, Ulrich , SCHMIDT, Beate , FLOCKERZI, Dieter , CHIESA, Maria Vittoria , HATZELMANN, Armin , ZITT, Christof , WOHLSEN, Andrea , MARX, Degenhard , KLEY, Hans-peter
发明人： KAUTZ, Ulrich , SCHMIDT, Beate , FLOCKERZI, Dieter , CHIESA, Maria Vittoria , HATZELMANN, Armin , ZITT, Christof , WOHLSEN, Andrea , MARX, Degenhard , KLEY, Hans-peter
IPC分类号： C07D401/04 , C07D401/14 , A61K31/473 , A61P29/00 , A61P11/00
CPC分类号： C07D401/04
摘要： Compounds of a certain formula (I), in which R1 , R2, R3, R31, R4, R5, R51 and Har have the meanings indicated in the description, are novel effective PDE4 inhibitors.
摘要翻译： 其中R1，R2，R3，R31，R4，R5，R51和Har具有说明书中所示含义的某种式（I）的化合物是新的有效的PDE4抑制剂。
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4.发明申请COMBINATION OF HMG-COA REDUCTASE INHIBITORS WITH PHOSPHODIESTERASE 4 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY PULMONARY DISEASES 审中-公开HMG-COA还原酶抑制剂与磷酸二酯酶4抑制剂联合治疗炎性肺部疾病
公开(公告)号：WO2008003701A3
公开(公告)日：2008-03-13
申请号：PCT/EP2007056683
申请日：2007-07-03
IPC分类号： A61K31/44 , A61K31/22 , A61K31/277 , A61K31/343 , A61K31/352 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/437 , A61K31/4439 , A61K31/453 , A61K31/502 , A61K31/505 , A61P11/00
CPC分类号： A61K31/505 , A61K31/22 , A61K31/277 , A61K31/343 , A61K31/352 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/437 , A61K31/44 , A61K31/4425 , A61K31/4439 , A61K31/453 , A61K31/502 , A61K45/06 , A61K2300/00
摘要： The invention relates to the combined use of a PDE4 inhibitor with a HMG-CoA reductase inhibitor for the preventive and curative treatment of an inflammatory pulmonary disease.
摘要翻译： 本发明涉及PDE4抑制剂与HMG-CoA还原酶抑制剂组合用于预防性和治疗性治疗炎性肺病。
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公开(公告)号：WO2006027345A2
公开(公告)日：2006-03-16
申请号：PCT/EP2005054365
申请日：2005-09-05
申请人： ALTANA PHARMA AG , FLOCKERZI DIETER , KAUTZ ULRICH , HATZELMANN ARMIN , ZITT CHRISTOF , WOHLSEN ANDREA , MARX DEGENHARD , KLEY HANS-PETER , CHRISTOFFERS JENS , ROSIAK ANNA
发明人： FLOCKERZI DIETER , KAUTZ ULRICH , HATZELMANN ARMIN , ZITT CHRISTOF , WOHLSEN ANDREA , MARX DEGENHARD , KLEY HANS-PETER , CHRISTOFFERS JENS , ROSIAK ANNA
CPC分类号： C07D495/04
摘要： Compounds of a certain formula 1, in which A, R1, R2 and R3 have the meanings indicated in the de- scription, are novel effective PDE4 inhibitors.
摘要翻译： 其中A，R1，R2和R3具有说明中所示含义的某些式1化合物是新型有效的PDE4抑制剂。
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公开(公告)号：WO2008138939A1
公开(公告)日：2008-11-20
申请号：PCT/EP2008/055867
申请日：2008-05-14
申请人： NYCOMED GMBH , SCHMIDT, Beate , SCHEUFLER, Christian , VOLZ, Jürgen , FETH, Martin P. , HUMMEL, Rolf-Peter , HATZELMANN, Armin , ZITT, Christof , WOHLSEN, Andrea , MARX, Degenhard , KLEY, Hans-Peter , OCKERT, Deborah , HEUSER, Anke , CHRISTIAANS, Johannes A. M. , STERK, Geert Jan , MENGE, Wiro M. P. B.
发明人： SCHMIDT, Beate , SCHEUFLER, Christian , VOLZ, Jürgen , FETH, Martin P. , HUMMEL, Rolf-Peter , HATZELMANN, Armin , ZITT, Christof , WOHLSEN, Andrea , MARX, Degenhard , KLEY, Hans-Peter , OCKERT, Deborah , HEUSER, Anke , CHRISTIAANS, Johannes A. M. , STERK, Geert Jan , MENGE, Wiro M. P. B.
IPC分类号： C07D401/14 , C07D405/14 , C07D413/14 , C07D417/14 , A61K31/444 , A61K31/4155 , A61P1/00 , A61P11/00 , A61P17/00
CPC分类号： C07D401/14 , A61K31/4152
摘要： The compounds of a certain formula (1), in which R1, R7, R8, R9 and n have the meanings as given in the description, are novel effective inhibitors of the type 4 phosphodiesterase.
摘要翻译： 其中R1，R7，R8，R9和n具有如说明书中给出的含义的某种式（1）的化合物是4型磷酸二酯酶的新型有效抑制剂。
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7.发明申请COMBINATION OF HMG-COA REDUCTASE INHIBITORS WITH PHOSPHODIESTERASE 4 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY PULMONARY DISEASES 审中-公开HMG-COA还原酶抑制剂与磷酸二酯酶4抑制剂联合用于治疗炎症性肺炎
公开(公告)号：WO2008003701A2
公开(公告)日：2008-01-10
申请号：PCT/EP2007/056683
申请日：2007-07-03
CPC分类号： A61K31/505 , A61K31/22 , A61K31/277 , A61K31/343 , A61K31/352 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/437 , A61K31/44 , A61K31/4425 , A61K31/4439 , A61K31/453 , A61K31/502 , A61K45/06 , A61K2300/00
摘要： The invention relates to the combined use of a PDE4 inhibitor with a HMG-CoA reductase inhibitor for the preventive and curative treatment of an inflammatory pulmonary disease.
摘要翻译： 本发明涉及PDE4抑制剂与HMG-CoA还原酶抑制剂的组合使用，用于预防和治疗炎性肺部疾病。
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公开(公告)号：WO2006027345A3
公开(公告)日：2006-03-16
申请号：PCT/EP2005/054365
申请日：2005-09-05
申请人： ALTANA PHARMA AG , FLOCKERZI, Dieter , KAUTZ, Ulrich , HATZELMANN, Armin , ZITT, Christof , WOHLSEN, Andrea , MARX, Degenhard , KLEY, Hans-Peter , CHRISTOFFERS, Jens , ROSIAK, Anna
发明人： FLOCKERZI, Dieter , KAUTZ, Ulrich , HATZELMANN, Armin , ZITT, Christof , WOHLSEN, Andrea , MARX, Degenhard , KLEY, Hans-Peter , CHRISTOFFERS, Jens , ROSIAK, Anna
IPC分类号： C07D495/06 , A61P11/00 , A61K31/4745
摘要： Compounds of a certain formula 1, in which A, R1, R2 and R3 have the meanings indicated in the de- scription, are novel effective PDE4 inhibitors.
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公开(公告)号：WO2006027344A2
公开(公告)日：2006-03-16
申请号：PCT/EP2005/054364
申请日：2005-09-05
申请人： ALTANA PHARMA AG , FLOCKERZI, Dieter , KAUTZ, Ulrich , HATZELMANN, Armin , ZITT, Christof , WOHLSEN, Andrea , MARX, Degenhard , KLEY, Hans-Peter , CHRISTOFFERS, Jens , ROSIAK, Anna
发明人： FLOCKERZI, Dieter , KAUTZ, Ulrich , HATZELMANN, Armin , ZITT, Christof , WOHLSEN, Andrea , MARX, Degenhard , KLEY, Hans-Peter , CHRISTOFFERS, Jens , ROSIAK, Anna
CPC分类号： C07D491/04
摘要： Compounds of a certain formula 1, in which R1, R2 and R3 have the meanings indicated in the description, are novel effective PDE4 inhibitors.
摘要翻译： R1，R2和R3具有说明书中所示含义的某种式1的化合物是新的有效的PDE4抑制剂。
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