公开(公告)号：WO1998009872A2

公开(公告)日：1998-03-12

申请号：PCT/US1997014644

申请日：1997-08-29

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  COELHO, Philip, H. ,  WOLF, Ludwig, Jr. ,  FISHER, David, P. ,  WONS, Allen, R. ,  BRATTEN, William

IPC: B65D00/00

CPC classification number: A61J1/10 ,  A61J1/12 ,  B29C35/041 ,  B29C65/04 ,  B29C66/0242 ,  B29C66/1122 ,  B29C66/3452 ,  B29C66/53262 ,  B29C66/71 ,  B29C66/8242 ,  B29C66/8322 ,  B29L2031/7148 ,  B29K2023/06 ,  B29K2023/083 ,  B29K2023/086 ,  B29K2023/12 ,  B29K2027/06

Abstract: A flexible, three-dimensional container is made by a prescribed vacuum-molding and heat sealing process. The container possesses a precise, defined geometry before and during use. The container is formed from first and second walls. The first wall has a planar area and a vacuum-molded cavity area drawn out of the plane of the planar area into a predefined three-dimensional geometry. A second wall overlies the first wall to close the cavity area and thereby forms an interior compartment. A thermal seal joins the two walls together. The seal is formed by heating the second wall and the first wall in the planar area, while assuring that the cavity area of the first wall is not subject to heating and possible deformation of its precise vacuum-molded geometry.

Abstract translation: 通过规定的真空成型和热封工艺制成柔软的三维容器。 容器在使用之前和使用期间具有精确的定义的几何形状。 容器由第一和第二壁形成。 第一壁具有平面区域和从平面区域的平面引出到预定义的三维几何形状的真空模制空腔区域。 第二壁覆盖第一壁以封闭空腔区域，从而形成内部隔室。 热封将两个墙壁连在一起。 密封件通过加热平面区域中的第二壁和第一壁而形成，同时确保第一壁的空腔区域不受其加热和其精确的真空模制几何形状的可能的变形。

公开(公告)号：WO1995015681A1

公开(公告)日：1995-06-15

申请号：PCT/US1994001664

申请日：1994-02-17

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  MARTINSON, Jeffrey ,  BRATTEN, William ,  WANG, Li, Ming ,  CHAPMAN, John

IPC: A01N01/02

CPC classification number: G01N33/56983 ,  B01D17/0217 ,  B01D21/2405 ,  B01D21/2444 ,  B01D21/245 ,  B01D21/26 ,  B01D21/262 ,  B01D2221/10 ,  C12Q1/6806 ,  C12Q1/70 ,  G01N1/40 ,  G01N33/491 ,  G01N33/5091 ,  G01N33/5094 ,  G01N33/56972

Abstract: A method and apparatus for creating a leukocyte rich sample from a mixed population of blood cells. The method comprises the steps of: separating an amount of blood into layers that include a buffy coat layer having a mixed population of blood cells including plasma and red blood cells; providing a chamber having an opening for receiving a fluid; causing the buffy coat layer to enter the chamber; centrifuging the chamber to separate the buffy coat layer into at least a plasma containing layer, a leukocyte containing layer, and a red blood cell containing layer; and separating the leukocyte containing layer from the other layers in the chamber.

Abstract translation: 一种用于从血液细胞的混合群体中产生富含白细胞的样品的方法和装置。 该方法包括以下步骤：将一定量的血液分离成包括具有包括血浆和红细胞在内的混合血细胞群的血沉棕黄层; 提供具有用于接收流体的开口的室; 使血沉棕黄层进入腔室; 离心室以将血沉棕黄层分成至少含血浆的层，含白细胞的层和含红细胞的层; 并将所述含白细胞的层与所述室中的其它层分离。

公开(公告)号：WO1995002325A1

公开(公告)日：1995-01-26

申请号：PCT/US1994007508

申请日：1994-07-06

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  WOLF, Ludwig, Jr. ,  BRATTEN, William ,  FOLEY, John

IPC: A01N01/02

CPC classification number: A61L2/0052 ,  A61K35/14 ,  A61K35/16 ,  A61L2/0011 ,  A61L2/0088 ,  A61L2/08 ,  A61L2202/22 ,  A61M1/3616

Abstract: A method and apparatus for virally inactivating a body fluid wherein a mixture including a therapeutically effective amount of methylene blue and an amount of a body fluid is formed in a container under sterile conditions and then the container is irradiated with a light field of a suitable intensity and wavelength for activating the methylene blue for a time sufficient to inactivate viruses in the mixture, while maintaining the mixture in a substantially static state within the container.

Abstract translation: 一种用于病毒灭活体液的方法和装置，其中在无菌条件下在容器中形成包含治疗有效量的亚甲基蓝和一定量体液的混合物，然后用适当强度的光场照射容器 和用于激活亚甲蓝的时间足以使混合物中的病毒灭活的时间，同时将混合物保持在容器内基本上静止的状态。