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    ELECTRODE ASSEMBLY FOR MEASUREMENT OF PLATELET FUNCTION IN WHOLE BLOOD
    5.
    发明申请
    ELECTRODE ASSEMBLY FOR MEASUREMENT OF PLATELET FUNCTION IN WHOLE BLOOD 审中-公开
    电极组件用于测量全血中的血小板功能

    公开(公告)号：WO2016196236A1

    公开(公告)日：2016-12-08

    申请号：PCT/US2016/034501

    申请日：2016-05-27

    Applicant: CA CASYSO AG ,  HILLMAN, Robert

    Inventor： HILLMAN, Robert ,  GORIN, Michael M. ,  McCLUSKEY, Cory Lee

    IPC: G01N27/02 ,  G01N27/06 ,  G01N27/07

    CPC classification number: G01N33/48707 ,  G01N27/07

    Abstract: A platelet impedance measurement system including an electrode assembly allows for measurement of platelet function in blood. The assembly includes a substrate that acts as a substantially rigid base and includes an electrode. A portion of the electrode is exposed such that, when the electrode is placed in blood, the exposed portion is in contact with the blood for measuring impedance changes as platelets adhere to the electrode. Wires of the electrode can be attached to each end of the substrate and can run within a groove along a portion of the substrate. The substrate includes an open area where the wires in the groove exit and re¬ enter the substrate at the end of the substrate, allowing the wires to be exposed to the blood. The open area includes a brace, ensuring that the exposed wires are held in the appropriate placement relative to each other and to the cuvette.

    Abstract translation: 包括电极组件的血小板阻抗测量系统允许测量血液中的血小板功能。 组件包括用作基本上刚性的基底并包括电极的基底。 电极的一部分被暴露，使得当电极放置在血液中时，暴露部分与血液接触，用于测量血小板粘附到电极上的阻抗变化。 电极的电线可以附着到基底的每个端部，并且可以沿着衬底的一部分在沟槽内延伸。 衬底包括开口区域，其中沟槽中的电线在衬底的端部处退出并进入衬底，允许电线暴露于血液。 开放区域包括支架，确保暴露的电线相对于彼此和比色杯保持在适当的位置。

    AUTOPLATELET CARTRIDGE DEVICE
    6.
    发明申请
    AUTOPLATELET CARTRIDGE DEVICE 审中-公开

    公开(公告)号：WO2019013993A1

    公开(公告)日：2019-01-17

    申请号：PCT/US2018/040120

    申请日：2018-06-28

    Applicant: CA CASYSO GMBH ,  HILLMAN, Robert

    Inventor： HILLMAN, Robert ,  GORIN, Michael, M. ,  McCLUSKEY, Cory, Lee ,  SCHWAIGER, Hubert, Martin

    IPC: A61J1/05 ,  A61K35/19 ,  B01L3/00 ,  C12M1/36 ,  C12Q1/56 ,  G01N33/86

    Abstract: Embodiments of a platelet testing system include an analyzer console device and a blood testing cartridge configured to releasably install into the console device. The cartridge device is configured with one or more measuring chambers and one or more mixing chambers that are fluidically connected within the cartridge device that enable the mixing of saline and a blood sample to a desired dilution. Additionally, the cartridge device is further configured with a cartridge slider that provides a reagent bead to the saline and blood mixture at a desired time. As such, one or more platelet activation assays can be conducted by measuring, through cartridge electrodes of the cartridge device, the detectable changes in platelet activity within the blood and saline mixture.

    SYSTEM, METHOD AND APPARATUS FOR ERROR CORRECTION IN MULTI-PROCESSOR SYSTEMS
    7.
    发明申请
    SYSTEM, METHOD AND APPARATUS FOR ERROR CORRECTION IN MULTI-PROCESSOR SYSTEMS 审中-公开
    用于多处理器系统中错误校正的系统，方法和装置

    公开(公告)号：WO2012058597A1

    公开(公告)日：2012-05-03

    申请号：PCT/US2011/058394

    申请日：2011-10-28

    Applicant: MAXWELL TECHNOLOGIES, INC. ,  HILLMAN, Robert ,  WILLIAMSON, Gale

    Inventor： HILLMAN, Robert ,  WILLIAMSON, Gale

    IPC: G06F11/00

    CPC classification number: G06F11/073 ,  G06F11/0724 ,  G06F11/0763 ,  G06F11/1658 ,  G06F11/184 ,  G06F2201/83

    Abstract: This disclosure provides apparatus, methods and systems for error correction in multi processor systems. Some implementations include a plurality of computing modules, each computing module including a processor. Each processor may include processing state. In some other implementations, each computing module may also include a memory. Upon receiving a signal to perform a partial re-synchronization, a hash of each processor's state data may be performed. In some embodiments, a hash of at least a portion of each computing module's memory data may also be performed. The hashes for each processor are then compared to determine majority hashes and possible minority hashes. Upon identifying a minority hash, the computing module that produced the minority hash may receive new processing state data from one of the computing modules that produced a majority hash.

    Abstract translation: 本公开提供了用于多处理器系统中的纠错的装置，方法和系统。 一些实施方式包括多个计算模块，每个计算模块包括处理器。 每个处理器可以包括处理状态。 在一些其他实现中，每个计算模块还可以包括存储器。 在接收到执行部分重新同步的信号时，可以执行每个处理器的状态数据的散列。 在一些实施例中，还可以执行每个计算模块的存储器数据的至少一部分的散列。 然后对每个处理器的散列进行比较，以确定大多数散列和可能的少数散列。 在识别少数散列时，产生少数散列的计算模块可以从产生多数散列的计算模块之一接收新的处理状态数据。

    CONTROLLED BLOOD DELIVERY TO MIXING CHAMBER OF A BLOOD TESTING CARTRIDGE
    8.
    发明申请
    CONTROLLED BLOOD DELIVERY TO MIXING CHAMBER OF A BLOOD TESTING CARTRIDGE 审中-公开
    控制血液输送到血液测试盒混合室

    公开(公告)号：WO2018045114A1

    公开(公告)日：2018-03-08

    申请号：PCT/US2017/049505

    申请日：2017-08-30

    Applicant: CA CASYSO GMBH ,  HILLMAN, Robert

    Inventor： HILLMAN, Robert ,  GORIN, Michael, M. ,  McCLUSKEY, Cory, Lee ,  SCHWAIGER, Hubert, Martin

    IPC: B01L3/00 ,  A61M39/00 ,  G01N33/48

    Abstract: Embodiments of a blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site. In some embodiments, the blood coagulation testing system includes a single-use cartridge component configured to measure and mix reagents with blood received from a blood sample reservoir. A mixing chamber in the single-use cartridge includes different reagent beads that, when exposed to a pre-determined volume of blood, dissolve and mix specific reagents with the blood. The assembled blood cartridge further includes configurations that are designed to prevent blood from prematurely mixing with reagent beads in the mixing chamber and to guide blood flow in the mixing chamber to dissolve reagent beads in a desired order. Thus, the mixture obtained from the mixing chamber can be readily utilized to generate results for the blood coagulation testing system.

    Abstract translation: 血液凝固测试系统的实施例可以作为例如在护理点处特别有用的自动血栓弹性测量系统进行操作。 在一些实施例中，血液凝固测试系统包括一次性药筒组件，该一次性药筒组件被配置成用从血液样本容器接收的血液来测量和混合试剂。 一次性药筒中的混合室包含不同的试剂珠，当暴露于预定体积的血液时，溶解并混合特定试剂与血液。 组装的血液盒还包括设计成防止血液过早地与混合室中的试剂珠混合并且引导混合室中的血流以期望的顺序溶解试剂珠的构造。 因此，从混合室获得的混合物可以容易地用于生成血液凝固测试系统的结果。

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