AUTOPLATELET CARTRIDGE DEVICE
    5.
    发明申请

    公开(公告)号:WO2019013993A1

    公开(公告)日:2019-01-17

    申请号:PCT/US2018/040120

    申请日:2018-06-28

    Abstract: Embodiments of a platelet testing system include an analyzer console device and a blood testing cartridge configured to releasably install into the console device. The cartridge device is configured with one or more measuring chambers and one or more mixing chambers that are fluidically connected within the cartridge device that enable the mixing of saline and a blood sample to a desired dilution. Additionally, the cartridge device is further configured with a cartridge slider that provides a reagent bead to the saline and blood mixture at a desired time. As such, one or more platelet activation assays can be conducted by measuring, through cartridge electrodes of the cartridge device, the detectable changes in platelet activity within the blood and saline mixture.

    CONTROLLED BLOOD DELIVERY TO MIXING CHAMBER OF A BLOOD TESTING CARTRIDGE
    6.
    发明申请
    CONTROLLED BLOOD DELIVERY TO MIXING CHAMBER OF A BLOOD TESTING CARTRIDGE 审中-公开
    控制血液输送到血液测试盒混合室

    公开(公告)号:WO2018045114A1

    公开(公告)日:2018-03-08

    申请号:PCT/US2017/049505

    申请日:2017-08-30

    Abstract: Embodiments of a blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site. In some embodiments, the blood coagulation testing system includes a single-use cartridge component configured to measure and mix reagents with blood received from a blood sample reservoir. A mixing chamber in the single-use cartridge includes different reagent beads that, when exposed to a pre-determined volume of blood, dissolve and mix specific reagents with the blood. The assembled blood cartridge further includes configurations that are designed to prevent blood from prematurely mixing with reagent beads in the mixing chamber and to guide blood flow in the mixing chamber to dissolve reagent beads in a desired order. Thus, the mixture obtained from the mixing chamber can be readily utilized to generate results for the blood coagulation testing system.

    Abstract translation: 血液凝固测试系统的实施例可以作为例如在护理点处特别有用的自动血栓弹性测量系统进行操作。 在一些实施例中,血液凝固测试系统包括一次性药筒组件,该一次性药筒组件被配置成用从血液样本容器接收的血液来测量和混合试剂。 一次性药筒中的混合室包含不同的试剂珠,当暴露于预定体积的血液时,溶解并混合特定试剂与血液。 组装的血液盒还包括设计成防止血液过早地与混合室中的试剂珠混合并且引导混合室中的血流以期望的顺序溶解试剂珠的构造。 因此,从混合室获得的混合物可以容易地用于生成血液凝固测试系统的结果。

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