利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

35 条记录 (耗时 0.018 秒)

    OPTOFLUIDIC MICROSCOPE DEVICE
    6.
    发明申请
    OPTOFLUIDIC MICROSCOPE DEVICE 审中-公开
    光学显微镜装置

    公开(公告)号：WO2005121749A2

    公开(公告)日：2005-12-22

    申请号：PCT/US2005/016876

    申请日：2005-05-12

    申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY ,  YANG, Changhuei ,  PSALTIS, Demetri

    发明人： YANG, Changhuei ,  PSALTIS, Demetri

    IPC分类号： G01N21/00

    CPC分类号： G01N21/6458 ,  B82Y10/00 ,  B82Y20/00

    摘要： An optofluidic microscope device is disclosed. The device includes a fluid channel having a surface and an object such as a bacterium or virus may flow through the fluid channel. Light imaging elements in the bottom of the fluid channel may be used to image the object.

    摘要翻译： 公开了一种光流体显微镜装置。 该装置包括具有表面的流体通道，诸如细菌或病毒的物体可以流过流体通道。 流体通道底部的光成像元件可用于成像物体。

    MULTIPLEXED FOURIER PTYCHOGRAPHY IMAGING SYSTEMS AND METHODS
    7.
    发明申请
    MULTIPLEXED FOURIER PTYCHOGRAPHY IMAGING SYSTEMS AND METHODS 审中-公开
    多重傅立叶成像系统和方法

    公开(公告)号：WO2016090331A1

    公开(公告)日：2016-06-09

    申请号：PCT/US2015/064126

    申请日：2015-12-04

    申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY

    发明人： HORSTMEYER, Roarke W. ,  ZHENG, Guoan ,  YANG, Changhuei

    IPC分类号： G02B21/36

    CPC分类号： G02B21/367 ,  G02B27/58

    摘要： Certain embodiments pertain to Multiplexed Fourier Ptychographic imaging systems and methods. In one example, the Multiplexed Fourier Ptychographic imaging system includes an LED array configured to illuminate a sequence of LED patterns for illuminating a sample being imaged. The system includes LED circuitry configured to independently control power to turn on multiple LEDs simultaneously in each LED pattern of the array. The system has a light detector that acquires a first set of lower resolution images of the sample each image acquired during exposure time during illumination by a unique LED pattern. The system uses the first set of lower resolution images to generate a second set of lower resolution images associated with each LED in the LED array and iteratively updates overlapping regions in the Fourier domain with the second set of lower resolution images to generate a higher resolution image.

    摘要翻译： 某些实施例涉及多路复用傅立叶Ptychographic成像系统和方法。 在一个示例中，多路复用傅立叶谱图成像系统包括被配置为照亮一系列LED图案以照射被成像的样品的LED阵列。 该系统包括配置成独立控制电源以在阵列的每个LED图案中同时打开多个LED的LED电路。 该系统具有光检测器，其通过独特的LED图案获得在照射期间的曝光时间期间获取的每个图像的样本的第一组较低分辨率图像。 该系统使用第一组较低分辨率图像来产生与LED阵列中的每个LED相关联的第二组较低分辨率图像，并且用第二组较低分辨率图像迭代地更新傅立叶域中的重叠区域以产生较高分辨率图像 。

    HIGH RESOLUTION IMAGING DEVICES WITH WIDE FIELD AND EXTENDED FOCUS
    8.
    发明申请
    HIGH RESOLUTION IMAGING DEVICES WITH WIDE FIELD AND EXTENDED FOCUS 审中-公开
    高分辨率成像设备，具有广泛的视野和扩展的焦点

    公开(公告)号：WO2011106327A2

    公开(公告)日：2011-09-01

    申请号：PCT/US2011/025762

    申请日：2011-02-22

    申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY ,  PAVANI, Sri Rama Prasanna ,  YANG, Changhuei ,  WU, Jigang

    发明人： PAVANI, Sri Rama Prasanna ,  YANG, Changhuei ,  WU, Jigang

    IPC分类号： G01B11/24 ,  G01N21/00

    CPC分类号： H04N13/207 ,  G02B21/16 ,  G02B21/361 ,  G02B27/2242 ,  G02B27/2285 ,  H04N13/221 ,  H04N13/254

    摘要： Embodiments of the present invention relate to a high-resolution imaging device with wide field and extended focus comprising a beam generator for generating a plurality of nondiffracting beams and a scanning mechanism for moving the plurality of nondiffracting beams relative to the object to illuminate a volume of the object. The high-resolution imaging device also comprises surface element and a body having a light detector layer outside the surface element. The light detector layer has a light detector configured to measure light data associated with the plurality of nondiffracting beams illuminating the volume of the object. In some cases, the high-resolution imaging device also includes a lens inside of the light detector layer. The lens is configured to focus the light on the light detector surface.

    摘要翻译： 本发明的实施例涉及一种具有宽视野和扩展焦点的高分辨率成像装置，其包括用于产生多个非衍射光束的光束发生器和用于相对地移动多个非衍射光束的扫描机构 到物体照亮物体的体积。 高分辨率成像装置还包括表面元件和在表面元件外具有光检测器层的主体。 光检测器层具有光检测器，光检测器被配置成测量与照射对象的体积的多个非衍射光束相关联的光数据。 在一些情况下，高分辨率成像装置还包括在光检测器层内部的透镜。 镜头配置为将光线聚焦在光检测器表面上。

    WAVEFRONT IMAGING SENSOR
    9.
    发明申请
    WAVEFRONT IMAGING SENSOR 审中-公开
    WAVEFRONT成像传感器

    公开(公告)号：WO2010141702A2

    公开(公告)日：2010-12-09

    申请号：PCT/US2010/037235

    申请日：2010-06-03

    申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY ,  CUI, Xiquan ,  YANG, Changhuei

    发明人： CUI, Xiquan ,  YANG, Changhuei

    IPC分类号： G01J9/00

    CPC分类号： G01J9/0215 ,  G02B21/0004 ,  G02B21/0092

    摘要： Embodiments of the present invention relate to a wavefront imaging sensor (WIS) comprising an aperture layer having an aperture, a light detector having a surface, and a transparent layer between the aperture layer and the light detector. The light detector can receive a light projection at the surface from light passing through the aperture. The light detector can also separately measure amplitude and phase information of a wavefront at the aperture based on the received light projection. The transparent layer has a thickness designed to locate the surface of the light detector approximately at a self-focusing plane in a high Fresnel number regime to narrow the light projection.

    摘要翻译： 本发明的实施例涉及一种波前成像传感器（WIS），其包括具有孔径的孔径层，具有表面的光检测器和在孔径层和光检测器之间的透明层。 光检测器可以从穿过孔的光接收表面的光投影。 光检测器还可以基于接收到的光投影单独测量孔径处的波前的幅度和相位信息。 透明层具有设计成将光检测器的表面大致位于具有高菲涅尔数状态的自聚焦平面上以使光投影变窄的厚度。

    OPTOFLUIDIC MICROSCOPE DEVICE WITH PHOTOSENSOR ARRAY
    10.
    发明申请
    OPTOFLUIDIC MICROSCOPE DEVICE WITH PHOTOSENSOR ARRAY 审中-公开
    带有光电传感器阵列的光学显微镜装置

    公开(公告)号：WO2009111573A2

    公开(公告)日：2009-09-11

    申请号：PCT/US2009/036045

    申请日：2009-03-04

    申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY ,  CUI, Xiquan ,  HENG, Xin ,  LEE, Lap Man ,  YANG, Changhuei

    发明人： CUI, Xiquan ,  HENG, Xin ,  LEE, Lap Man ,  YANG, Changhuei

    IPC分类号： G02B21/32

    CPC分类号： G01N21/53 ,  G01N21/6458

    摘要： Embodiments of the present invention relate to techniques for improving optofluidic microscope (OFM) devices. One technique which may be used eliminates the aperture layer covering the light detector layer. Other techniques retain the aperture layer, reversing the relative position of the light source and light detector such that light passes through the aperture layer before passing through the fluid channel to the light detector. Another technique adds an optical tweezer for controlling the movement of objects moving through the fluid channel. Another technique adds an optical fiber bundle to relay light from light transmissive regions to a remote light detector. Another technique adds two electrodes at ends of the fluid channel to generate an electrical field capable of moving objects through the fluid channel while suppressing rotation. These techniques can be employed separately or in combination to improve the capabilities of OFM devices.

    摘要翻译： 本发明的实施例涉及用于改进光流体显微镜（OFM）装置的技术。 可以使用的一种技术消除了覆盖光检测器层的孔径层。 其他技术保留孔径层，反转光源和光检测器的相对位置，使得光在通过流体通道之前通过孔层，到达光检测器。 另一种技术增加了用于控制移动通过流体通道的物体的运动的光学镊子。 另一种技术增加了光纤束将光从透光区域转移到远程光检测器。 另一种技术在流体通道的端部添加两个电极，以产生能够通过流体通道移动物体同时抑制旋转的电场。 这些技术可以单独使用或组合使用以提高OFM设备的能力。