公开(公告)号：WO2023278798A1

公开(公告)日：2023-01-05

申请号：PCT/US2022/035859

申请日：2022-06-30

Applicant: CEPHEID ,  NANDURI, Harika ,  WEITSMAN, Andrew ,  GLASS, Jennifer ,  WEI, Michelle ,  NOYES, Tina

Inventor： NANDURI, Harika ,  WEITSMAN, Andrew ,  GLASS, Jennifer ,  WEI, Michelle ,  NOYES, Tina

IPC: B01L3/00 ,  B01L2200/0647 ,  B01L2200/10 ,  B01L2300/0681 ,  B01L2400/06 ,  B01L2400/0644 ,  B01L3/502715 ,  B01L3/502738 ,  B01L3/502761 ,  B01L3/563

Abstract: Sample cartridge, valve assembly and processing methods for providing mechanical lysis, chemical lysis or both for a given fluid sample are provided herein. Such systems can include a sample processing cartridge having a valve assembly configured for transport of the processing of fluid sample within the sample cartridge. The valve assembly can include a valve body and cap that secure a filter therebetween and facilitate inflow of mechanical or chemical lysing agents as needed for a fluid sample. Assay workflows for performing both mechanical and chemical lysis of a fluid sample within the same workflow of a single universal sample cartridge are also provided.

公开(公告)号：WO2014052671A1

公开(公告)日：2014-04-03

申请号：PCT/US2013/062042

申请日：2013-09-26

Applicant: CEPHEID

Inventor： CHIANG, Yuh-Min ,  DORITY, Doug ,  DICKENS, Dustin ,  GLASS, Jennifer ,  VAN ATTA, Reuel

IPC: G01N35/08 ,  G01N33/487 ,  C12M1/38

CPC classification number: C12Q1/6876 ,  B01L3/502 ,  B01L3/5027 ,  B01L3/50851 ,  B01L7/52 ,  B01L2200/0642 ,  B01L2200/0673 ,  B01L2300/0636 ,  B01L2300/0819 ,  B01L2400/0406 ,  B01L2400/0487

Abstract: A honeycomb tube with a planar frame defining a fluidic path between a first planar surface and a second planar surface. A fluidic interface is located at one end of the planar frame. The fluidic interface has a fluidic inlet and fluidic outlet. The fluidic path further includes a well chamber having an well-substrate with a plurality of wells. The well chamber is arranged in the planar frame between the first or second surface and the well-substrate.

Abstract translation: 一种蜂窝管，其具有限定在第一平面和第二平面之间的流体路径的平面框架。 流体界面位于平面框架的一端。 流体界面具有流体入口和流体出口。 流体路径还包括具有多个孔的具有良好基底的井室。 阱室布置在第一或第二表面和阱基板之间的平面框架中。