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公开(公告)号：WO2021133614A1
公开(公告)日：2021-07-01
申请号：PCT/US2020/065383
申请日：2020-12-16
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： MA, Minh, T. , DELGADO, Sergio
IPC: A61F2/24 , A61B17/122 , A61F2/246 , A61F2/2466
Abstract: A valve repair device includes a pair of paddles and at least one leak control extension. The device can also include a spacer or coaption element. The pair of paddles can be coupled to the spacer or coaption element. The pair of paddles are movable between an open position and a closed position and are configured to attach the valve repair device to the native valve of the patient. The at least one leak control extension extends from the spacer and is configured to block retrograde blood flow along, adjacent, near, and/or around the device, for example, sides of the spacer or coaption element.
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公开(公告)号：WO2019139643A1
公开(公告)日：2019-07-18
申请号：PCT/US2018/045985
申请日：2018-08-09
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： METCHIK, Asher, L. , TYLER, Gregory, Scott, II , WINSTON, Matthew, T. , DELGADO, Sergio , FRESCHAUF, Lauren, R. , DIXON, Eric, Robert , SIEGEL, Alexander, J.
CPC classification number: A61F2/246 , A61F2/2466 , A61F2220/0016 , A61F2220/0025 , A61F2230/0013 , A61F2230/0045
Abstract: A system for implanting a repair device onto a native valve of a natural heart to repair the native valve of a patient during a non-open-heart procedure. The system includes a base assembly having a plurality of pivoting links, a pair of paddles attached to the base assembly, a pair of gripping members attached to the base assembly, and at least one coaptation or spacer element disposed between the pair of gripping members. Movement of the pivoting links of the base assembly causes the paddles to move between an open position and a closed position. The paddles and the gripping members are configured to attach to valve leaflets of the patient. The coaptation or spacer element is configured to fill at least a portion of a gap between the valve leaflets of the patient.
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公开(公告)号：WO2019182790A1
公开(公告)日：2019-09-26
申请号：PCT/US2019/021662
申请日：2019-03-11
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： STEARNS, Grant, Matthew , BAK-BOYCHUK, Gregory , DELGADO, Sergio
IPC: A61F2/24
Abstract: A coronary artery check valve (110A, 310, 410, 510) includes a stent (112, 312, 412, 512) configured to attach to an inner wall of a coronary artery of a living subject, and a tapered helical coil (116, 316, 416, 516) coupled to the stent (112, 312, 412, 512) and configured to regulate blood flow in the coronary artery. The coronary artery check valve (110A, 310, 410, 510) is configured to prevent retrograde flow of the coronary blood supply during diastole by closing during systole of the heart when the tapered helical coil (116, 316, 416, 516) compresses longitudinally, and opening when the tapered helical coil (116, 316, 416, 516) expands longitudinally to permit blood flow into the coronary artery when a coronary pressure of the living subject drops below diastolic blood pressure.
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公开(公告)号：WO2018195215A3
公开(公告)日：2018-10-25
申请号：PCT/US2018/028189
申请日：2018-04-18
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： DELGADO, Sergio , DIXON, Eric Robert , TAYLOR, David M. , METCHIK, Asher L. , WINSTON, Matthew , STEARNS, Grant Matthew , SOK, Sam , MARR, Devin H. , NGUYEN, Tam Van , DARABIAN, Sirous , TYLER, II, Gregory Scott , FRESCHAUF, Lauren R. , SIEGEL, Alexander J. , CHEN, Jensen , MORATORIO, Guillermo W. , KWON, Rhayoung
Abstract: An exemplary implantable prosthetic device has a coaption element and at least one anchor. The coaption element is configured to be positioned within the native heart valve orifice to help fill a space where the native valve is regurgitant and form a more effective seal. The coaption element can have a structure that is impervious to blood and that allows the native leaflets to close around the coaption element during ventricular systole to block blood from flowing from the left or right ventricle back into the left or right atrium, respectively. The coaption element can be connected to leaflets of the native valve by the anchor.
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公开(公告)号：WO2016183485A1
公开(公告)日：2016-11-17
申请号：PCT/US2016/032462
申请日：2016-05-13
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： CHAU, Mark , TAYLOR, David, M. , SIEGEL, Alexander, J. , OLSON, Christopher, J. , DELGADO, Sergio , COOPER, Alexander, H. , FRESCHAUF, Lauren, R. , METCHIK, Asher, L. , WINSTON, Matthew, T. , HERNANDEZ, Cristobal, R. , KARAPETIAN, Emil , KHUU, Bao , DIXON, Eric
IPC: A61F2/24
CPC classification number: A61F2/246 , A61F2/2454 , A61F2/2463 , A61F2/2466 , A61F2220/0016 , A61F2310/00023
Abstract: In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion, wherein the prosthetic device is movable between a compressed configuration, in which the spacer body portion is radially compressed and is axially spaced relative to the anchor portion, and an expanded configuration, in which the spacer body portion expands radially outwardly relative to the compressed configuration and overlaps at least a portion of the anchor portion.
Abstract translation: 在一个代表性的实施例中，可植入假体装置包括被配置为设置在心脏的天然传播单元之间的间隔体本体部分和被配置为将天然传单固定在间隔体主体部分上的锚定部分，其中假体装置可在压缩 配置，其中间隔件主体部分被径向压缩并且相对于锚固部分轴向间隔开，并且膨胀构型，其中间隔件主体部分相对于压缩构造径向向外扩张并与锚定部分的至少一部分重叠 。
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Patent Agency Ranking
公开(公告)号：WO2015077610A1
公开(公告)日：2015-05-28
申请号：PCT/US2014/066895
申请日：2014-11-21
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： DELGADO, Sergio , SCHNEIDER, Ralph , ROWE, Stanton, J. , WU, Ming, H. , JAFARI, Mohammad , BOOMGARDEN, Jon
IPC: A61B17/03 , A61B17/12 , A61M25/01 , A61M25/088
CPC classification number: A61B17/0057 , A61B17/0401 , A61B17/0644 , A61B17/068 , A61B17/3209 , A61B17/3423 , A61B17/3431 , A61B17/3462 , A61B17/3468 , A61B17/3478 , A61B2017/00247 , A61B2017/00252 , A61B2017/00477 , A61B2017/00526 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00623 , A61B2017/00668 , A61B2017/00867 , A61B2017/00986 , A61B2017/0414 , A61B2017/0427 , A61B2017/0464 , A61B2017/0641 , A61B2017/0645 , A61B2017/3425 , A61B2017/3458 , A61B2017/346 , A61B2017/3464
Abstract: Embodiments of the present disclosure are directed to implantable sealing devices, delivery apparatuses, and methods of their use, for closing surgical openings or defects in a sidewall of a vessel in a subject. In several embodiments, the disclosed implantable sealing devices, delivery apparatuses, and methods can be used to close a surgical opening in a sidewall of the heart.
Abstract translation: 本公开的实施例涉及可植入密封装置，递送装置及其使用方法，用于封闭受试者中血管侧壁中的手术开口或缺陷。 在几个实施例中，所公开的可植入密封装置，递送装置和方法可用于封闭心脏侧壁中的手术开口。
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公开(公告)号：WO2014039392A1
公开(公告)日：2014-03-13
申请号：PCT/US2013/057555
申请日：2013-08-30
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： CHAU, Mark , OBA, Travis , DELGADO, Sergio , TAFT, Robert, C. , ROWE, Stanton, J. , COOPER, Alexander, H.
CPC classification number: A61F2/2436 , A61F2/2412 , A61F2/243 , A61F2/2433 , A61F2/2442 , A61F2/2445 , A61F2/2454 , A61F2/2457 , A61F2/246 , A61F2/2463 , A61F2/2466 , A61F2230/0069 , A61F2250/0003
Abstract: This disclosure pertains generally to prosthetic devices and related methods for helping to seal native heart valves and prevent or reduce regurgitation therethrough, as well as devices and related methods for implanting such prosthetic devices. In some cases, a spacer having a single anchor can be implanted within a native heart valve. In some cases, a spacer having dual anchors can be implanted within a native heart valve. In some cases, devices can be used to extend the effective length of a native heart valve leaflet.
Abstract translation: 本公开总体上涉及用于帮助密封天然心脏瓣膜并防止或减少反流的假体装置和相关方法，以及用于植入这种假体装置的装置和相关方法。 在一些情况下，具有单个锚的间隔物可以植入天然心脏瓣膜内。 在一些情况下，具有双重锚的间隔物可以植入天然心脏瓣膜内。 在一些情况下，可以使用装置来延长天然心脏瓣膜小叶的有效长度。
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公开(公告)号：WO2023278663A2
公开(公告)日：2023-01-05
申请号：PCT/US2022/035672
申请日：2022-06-30
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： FRESCHAUF, Lauren R. , OBERWISE, Eric Michael , STEARNS, Grant Matthew , OKOS, Chris J. , HOFFER, Eran , NAWALAKHE, Rupesh Gajanan , PAWAR, Sandip Vasant , DELGADO, Sergio , ELTAL, Munir Hicham
IPC: A61F2/24 , A61F2/246 , A61F2/2466
Abstract: An implantable device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. The implantable device or implant can include a paddle frame that is adjustable in width. A coupler can be configured to allow for width adjustment of the paddle frame and to set or fix the width of the paddle frame. A cover can be configured to prevent or inhibit regurgitant blood flow regardless of the selected width of the paddle frame.
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公开(公告)号：WO2018209021A1
公开(公告)日：2018-11-15
申请号：PCT/US2018/031959
申请日：2018-05-10
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： MARR, Devin, H. , DELGADO, Sergio , DIXON, Eric, Robert , TAYLOR, David, M. , METCHIK, Asher, L. , WINSTON, Matthew, T. , STEARNS, Grant, Matthew , SOK, Sam , NGUYEN, Tam, Van , KWON, Rhayoung , WU, Victoria, Cheng-tan , WHITE, Amanda, Kristine, Anderson
Abstract: An implantable prosthetic device can include a spacer member, a plurality of anchors, and a plurality of clasps. The spacer member can be configured to be disposed between native leaflets of a heart. The anchors can be coupled to the spacer member and configured to secure the native leaflets against the spacer member. The clasps can be coupled to a respective anchor and configured to secure the native leaflets to the anchors. The clasps can be independently movable between an open configuration and a closed configuration.
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公开(公告)号：WO2018195201A1
公开(公告)日：2018-10-25
申请号：PCT/US2018/028171
申请日：2018-04-18
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： DIXON, Eric Robert , CHEN, Jensen , MORATORIO, Guillermo W. , CAO, Hengchu , DOMINICK, Douglas Thomas , DELGADO, Sergio , FRESCHAUF, Lauren R.
IPC: A61F2/24
Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are moveable from a closed position to an open position. The clasps are also moveable from an open position to a closed position. The implantable prosthetic device can be used to repair a naitive valve, such as a native mitral valve.
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