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    DEVICE AND METHOD FOR REPLACING MITRAL VALVE
    4.
    发明申请
    DEVICE AND METHOD FOR REPLACING MITRAL VALVE 审中-公开
    用于更换麻药阀的装置和方法

    公开(公告)号：WO2009134701A2

    公开(公告)日：2009-11-05

    申请号：PCT/US2009/041754

    申请日：2009-04-27

    Applicant: EDWARDS LIFESCIENCES CORPORATION ,  ROWE, Stanton, J. ,  CHAU, Mark ,  NGUYEN, Son, V.

    Inventor： ROWE, Stanton, J. ,  CHAU, Mark ,  NGUYEN, Son, V.

    IPC: A61F2/90 ,  A61F2/24

    CPC classification number: A61F2/2418 ,  A61B17/0401 ,  A61B2017/00243 ,  A61B2017/0417 ,  A61B2017/0496 ,  A61F2/2427 ,  A61F2/2436 ,  A61F2/2457 ,  A61F2/90 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0078 ,  A61F2250/0039 ,  A61L27/3625 ,  A61L27/50 ,  A61L2430/20

    Abstract: A prosthetic mitral valve assembly and method of inserting the same is disclosed. In certain disclosed embodiments, the prosthetic mitral valve assembly has a flared upper end and a tapered portion to fit the contours of the native mitral valve. The prosthetic mitral valve assembly can include a stent or outer support frame with a valve mounted therein. The assembly can be adapted to expand radially outwardly and into contact with the native tissue to create a pressure fit. One embodiment of a method includes positioning the mitral valve assembly below the annulus such that the annulus itself can restrict the assembly from moving in an upward direction towards the left atrium. The mitral valve assembly is also positioned so that the leaflets of the mitral valve hold the assembly to prevent downward movement of the assembly towards the left ventricle.

    Abstract translation: 公开了一种假体二尖瓣组件及其插入方法。 在某些公开的实施例中，假体二尖瓣组件具有扩张的上端和锥形部分以适应天然二尖瓣的轮廓。 假体二尖瓣组件可以包括其中安装有阀的支架或外部支撑框架。 组件可以适于径向向外膨胀并与天然组织接触以产生压力配合。 方法的一个实施例包括将二尖瓣组件定位在环空下方，使得环空本身可以限制组件向上朝向左心房移动。 二尖瓣组件也被定位成使得二尖瓣的小叶保持组件以防止组件朝向左心室向下移动。

    DEVICE FOR RESHAPING HEART ANATOMY
    5.
    发明申请
    DEVICE FOR RESHAPING HEART ANATOMY 审中-公开

    公开(公告)号：WO2020176212A1

    公开(公告)日：2020-09-03

    申请号：PCT/US2020/016942

    申请日：2020-02-06

    Applicant: EDWARDS LIFESCIENCES CORPORATION

    Inventor： NIA, Nima, V. ,  ROWE, Stanton, J. ,  MIRI, Behnood ,  MOYEDI, Zahra

    IPC: A61F2/24

    Abstract: A cardiac device comprises a first elongate member configured to contact a first area of tissue of a heart and a second elongate member configured to apply pressure to a second area of tissue of the heart. At least a portion of a ventricle is between the first area of tissue and the second area of tissue. The cardiac device further comprises a delivery mechanism configured to press the second elongate member towards the first elongate member to reduce a distance between the first area of tissue and the second area of tissue.

    DEVICES AND METHODS FOR REDUCING CARDIAC VALVE REGURGITATION
    9.
    发明申请
    DEVICES AND METHODS FOR REDUCING CARDIAC VALVE REGURGITATION 审中-公开
    减少心脏瓣膜注射的装置和方法

    公开(公告)号：WO2013173587A1

    公开(公告)日：2013-11-21

    申请号：PCT/US2013/041359

    申请日：2013-05-16

    Applicant: EDWARDS LIFESCIENCES CORPORATION

    Inventor： ROWE, Stanton, J. ,  SCHWARTZ, Robert ,  VAN TASSEL, Robert ,  KHALIL, Vivian ,  SPINNER, Erin ,  ZIMMERMAN, Neil ,  SIEGEL, Alexander, J. ,  NGUYEN, Son, V.

    IPC: A61F2/24 ,  A61M39/22 ,  A61F2/02

    CPC classification number: A61F2/2427 ,  A61F2/2424 ,  A61F2/2454 ,  A61F2/246 ,  A61F2/2463 ,  A61F2/2466 ,  A61F2210/0061 ,  A61F2230/0023 ,  A61F2250/0003 ,  A61F2250/001

    Abstract: The present invention relates to devices and methods for improving the function of a defective heart valve, and particularly for reducing regurgitation through an atrioventricular heart valve - i.e., the mitral valve and the tricuspid valve. For a tricuspid repair, the device includes an anchor deployed in the tissue of the right ventricle, in an orifice opening to the right atrium, or anchored to the tricuspid valve. A flexible anchor rail connects to the anchor and a coaptation element on a catheter rides over the anchor rail. The catheter attaches to the proximal end of the coaptation element, and a locking mechanism fixes the position of the coaptation element relative to the anchor rail. Finally, there is a proximal anchoring feature to fix the proximal end of the coaptation catheter subcutaneously adjacent the subclavian vein. The coaptation element includes an inert covering and helps reduce regurgitation through contact with the valve leaflets.

    Abstract translation: 本发明涉及用于改善有缺陷心脏瓣膜功能的装置和方法，特别涉及通过房室心脏瓣膜 - 即二尖瓣和三尖瓣瓣来减少反流。 对于三尖瓣修复，该装置包括部署在右心室的组织中的锚，在通向右心房的孔中，或锚定到三尖瓣。 柔性锚杆连接到锚固件上，导管上的接合元件越过锚杆。 导管附接到接合元件的近端，并且锁定机构固定接合元件相对于锚固轨道的位置。 最后，有一个近端锚固特征，将接合导管的近端固定在毗邻锁骨下静脉的位置。 接合元件包括惰性覆盖物，并通过与瓣膜传递接触来帮助减少反流。

    LOW-PROFILE HEART VALVE AND DELIVERY SYSTEM
    10.
    发明申请
    LOW-PROFILE HEART VALVE AND DELIVERY SYSTEM 审中-公开

    公开(公告)号：WO2011109801A3

    公开(公告)日：2011-09-09

    申请号：PCT/US2011/027351

    申请日：2011-03-07

    Applicant: EDWARDS LIFESCIENCES CORPORATION ,  BENICHOU, Netanel ,  ROWE, Stanton, J. ,  CHOW, Sean

    Inventor： BENICHOU, Netanel ,  ROWE, Stanton, J. ,  CHOW, Sean

    IPC: A61F2/24 ,  A61F2/82 ,  A61M29/02 ,  A61M25/01

    Abstract: Disclosed replacement heart valves can be designed to be delivered to a native valve site while crimped on a delivery catheter. The crimped profile of the replacement valve can be minimized by, for example, separating a frame or stent structure from a leaflet structure, along the axial direction. Disclosed replacement valves can be transitioned from a delivery configuration, in which the crimped profile can be minimized, to an operating configuration. The replacement valve can be fully assembled in both the delivery and operating configurations. In some embodiments, the leaflets can be positioned outside of the stent in the delivery configuration, and positioned inside of the stent lumen in the operating configuration. Disclosed replacement valves can include a flexible sleeve coupling the leaflets to the stent and facilitating the transition to the operating configuration. Methods of implanting said replacement valves are also disclosed.

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