OLIGOSACCHARIDE PRODUCTION
    1.
    发明申请
    OLIGOSACCHARIDE PRODUCTION 审中-公开
    低聚糖生产

    公开(公告)号:WO2015197082A1

    公开(公告)日:2015-12-30

    申请号:PCT/DK2015/050191

    申请日:2015-06-29

    申请人: GLYCOM A/S

    IPC分类号: C12P19/18 C12N1/21

    摘要: The invention relates to a genetically modified microorganism for making a recombinant oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source. The one or more genes encoding a sucrose utilization system are preferably one or more genes encoding a heterologous PTS-dependent sucrose utilization transport system, such as the scr genes.

    摘要翻译: 本发明涉及用于制备重组寡糖的转基因微生物,优选3-8个单糖单元,更优选3-5个单糖单元,特别是包含编码蔗糖利用系统的一个或多个基因的HMO,因此微生物 可以使用蔗糖作为碳源和能源。 编码蔗糖利用系统的一种或多种基因优选是编码异源PTS依赖性蔗糖利用转运系统(例如scr基因)的一种或多种基因。