-
公开(公告)号:WO2015197082A1
公开(公告)日:2015-12-30
申请号:PCT/DK2015/050191
申请日:2015-06-29
申请人: GLYCOM A/S
发明人: SAMAIN, Eric , PELTIER-PAIN, Pauline , BYCH, Katrine , JOHANSON, Ted , CHAMPION, Elise , DEKANY, Gyula
CPC分类号: C12P19/18 , C07K14/245 , C12N9/1029 , C12N9/1051 , C12N9/1205 , C12N9/2402 , C12N9/2471 , C12N15/52 , C12Y203/01018 , C12Y204/01149 , C12Y302/01023 , C12Y302/01026
摘要: The invention relates to a genetically modified microorganism for making a recombinant oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source. The one or more genes encoding a sucrose utilization system are preferably one or more genes encoding a heterologous PTS-dependent sucrose utilization transport system, such as the scr genes.
摘要翻译: 本发明涉及用于制备重组寡糖的转基因微生物,优选3-8个单糖单元,更优选3-5个单糖单元,特别是包含编码蔗糖利用系统的一个或多个基因的HMO,因此微生物 可以使用蔗糖作为碳源和能源。 编码蔗糖利用系统的一种或多种基因优选是编码异源PTS依赖性蔗糖利用转运系统(例如scr基因)的一种或多种基因。
-
公开(公告)号:WO2022013143A1
公开(公告)日:2022-01-20
申请号:PCT/EP2021/069310
申请日:2021-07-12
申请人: GLYCOM A/S
发明人: PEDERSEN, Margit , PAPADAKIS, Manos , BECKER, Peter , SAMAIN, Eric , PELTIER-PAIN, Pauline , KAMPMANN, Katrine Bych , JOHANSON, Ted , CHAMPION, Elise , DEKANY, Gyula
IPC分类号: C12P19/00 , C12P19/04 , C12P19/12 , C12P19/18 , C12P19/26 , C07K14/255 , C07K14/26 , C12N9/12 , C12N9/24 , C12N15/52
摘要: The invention relates to a genetically modified microorganism for making an oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source.
-