专利检索 ap:("GRÜNENTHAL GMBH") AND inv:"RIDER, David" 第 1 页

1.

发明申请
PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL 审中-公开

公开(公告)号：WO2019170904A1

公开(公告)日：2019-09-12

申请号：PCT/EP2019/055947

申请日：2019-03-11

申请人： GRÜNENTHAL GMBH

发明人： JAKOB, Florian , MERLA, Beatrix , RIDER, David , DUNKERN, Torsten , WAGENER, Markus

IPC分类号： C07D401/14 , C07D401/04 , C07D401/12 , C07D409/12 , C07D417/12 , C07D417/14 , C07D211/58 , C07D211/76 , A61K31/451 , A61K31/4535 , A61K31/4545 , A61P29/00

摘要： The present invention relates to a compound according to general formula (I) which acts as a modulator of FPR2 and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by FPR2.

2.

发明申请
6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL 审中-公开
标题翻译：用尿素和苯基取代6元环胺或内酰胺

公开(公告)号：WO2018054549A1

公开(公告)日：2018-03-29

申请号：PCT/EP2017/025264

申请日：2017-09-21

申请人： GRÜNENTHAL GMBH

发明人： JAKOB, Florian , NORDHOFF, Sonja , RIDER, David , WAGENER, Markus , BAHRENBERG, Gregor , DUNKERN, Torsten

IPC分类号： C07D401/12 , A61K31/445 , A61K31/45 , A61K31/4545 , C07D211/16 , C07D211/56 , C07D211/94

摘要： The present invention relates to a compound according to general formula (I) which acts as a modulator of FPR2 and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by FPR2.

摘要翻译： 本发明涉及通式（I）的化合物，其充当FPR2的调节剂并且可用于治疗和/或预防至少部分由FPR2介导的病症

3.

发明申请
NOVEL SUBSTITUTED 3-INDOLE AND 3-INDAZOLE COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS 审中-公开

公开(公告)号：WO2018234354A1

公开(公告)日：2018-12-27

申请号：PCT/EP2018/066357

申请日：2018-06-20

申请人： GRÜNENTHAL GMBH

发明人： KONETZKI, Ingo , JAKOB, Florian , WAGENER, Markus , DUNKERN, Torsten , RIDER, David , WELBERS, André

IPC分类号： C07D401/14 , C07D403/04 , C07D471/04 , A61K31/505 , A61K31/5377 , A61P25/00 , A61P29/00

摘要： The invention relates to novel 3-indole and 3-indazole compounds characterized in that the compound has general formula (I) in which the chemical groupings, substituents. variables and indices are as defined in the description, and to their use as medicaments, in particular as medicaments for the treatment of conditions and diseases that can be treated by inhibition of the PDE4 enzyme.

4.

发明申请
NOVEL SUBSTITUTED INDOLE AND INDAZOLE COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS 审中-公开

公开(公告)号：WO2018234353A1

公开(公告)日：2018-12-27

申请号：PCT/EP2018/066355

申请日：2018-06-20

申请人： GRÜNENTHAL GMBH

发明人： KONETZKI, Ingo , WAGENER, Markus , DUNKERN, Torsten , RIDER, David , WELBERS, André

IPC分类号： C07D401/14 , C07D401/04 , A61K31/444 , A61K31/4439 , A61P29/00 , A61P25/00

摘要： The invention relates to novel indole and indazole compounds characterized in that the compound has general formula (I), in which the chemical groupings, substituents, variables and indices are as defined in the description, and to their use as medicaments, in particular as medicaments for the treatment of conditions and diseases that can be treated by inhibition of the PDE4 enzyme.